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Evaluation of the biological activity of the disintegrin-like and cysteine-rich domains of Bothropasin, a metalloproteinase from Bothrops jararaca
(Universidade Federal de São Carlos, 2021-05-17)
Bothropasin is a 48kDa hemorrhagic class III Snake Venom Metalloproteinase (SVMP). As a multi-domain protein, it contains catalytic metalloproteinase (M), disintegrin-like (D), and cysteine rich domains (C). Integrins ...
Influência de complexos polipiridínicos de Ru(II) no processo de agregação do peptídeo beta amiloide
(Universidade Federal de São Carlos, 2023-02-27)
Most neurodegenerative diseases are associated with abnormal protein aggregation. Amyloid proteins are highly prone to aggregation and, consequently, accumulate in the brain, disrupting synapses and causing neurotoxicity. ...