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Influência de complexos polipiridínicos de Ru(II) no processo de agregação do peptídeo beta amiloide
(Universidade Federal de São Carlos, 2023-02-27)
Most neurodegenerative diseases are associated with abnormal protein aggregation. Amyloid proteins are highly prone to aggregation and, consequently, accumulate in the brain, disrupting synapses and causing neurotoxicity. ...
Influência do tipo de lipídeo e peptídeo beta amiloide sobre a perturbação da membrana e consequências na toxicidade de células neuronais observadas pelas respostas luminescentes do complexo RuApy
(Universidade Federal de São Carlos, 2023-08-28)
One of the hypotheses for the cause of Alzheimer's disease is the accumulation of amyloid-beta peptide (Aβ) aggregates in the brain that lead to severe synaptic and cognitive dysfunctions resulting in neurodegenerative ...