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Síntese de porfirinas contendo grupos do tipo uracil fundidos nas posições β-pirrólicas
(Universidade Federal de São Carlos, 2014-07-28)
In this work the synthesis of new porphyrin derivatives were proposed. The preparations of new compounds containing uracil groups at β-pirrolic position were studied based on their interest in organics synthesis. We ...
Síntese de clorinas anfifílicas com potenciais aplicações em terapia fotodinâmica
(Universidade Federal de São Carlos, 2012-10-26)
The main objective of this work was to construct amphiphilic chlorins with low aggregation in a physiological environment. The synthesis and structural characterization of the target compounds were carried out, and preliminary ...
Fotocatálise e suas aplicações em reações de ciclização oxidativa e terapia fotônicas
(Universidade Federal de São Carlos, 2019-05-06)
In the chapter 1, studies on photocatalysed reactions were carried out by porphyrins and other photocatalysts aiming at the formation of radicals in amino aromatic systems for subsequent addition reaction. More specifically, ...
Avaliação in vitro da ação fotodinâmica antimicrobiana e antitumoral do complexo cis-[Ru(phen)2(pPDIp)]2+
(Universidade Federal de São Carlos, 2021-02-19)
Photodynamic therapy (PDT) activates a photosensitizer by visible or infrared light to generate cytotoxic oxygen species that lead to cell death. PDT is generally used in applications in superficial lesions and can be used ...
Sobre a síntese de pirróis 3,4-dissubstituídos e seus correspondentes derivados porfirínicos
(Universidade Federal de São Carlos, 2014-02-28)
In this work we have developed the synthesis of 3,4-disubstituted pyrroles, aiming at the preparation of strategically designed (continue...)
Complexo luminescente de Ru(II)-Perileno: avaliação da citotoxicidade e da fotocitotoxicidade em células de melanoma murino B16F10 in vitro e in vivo
(Universidade Federal de São Carlos, 2017-08-17)
Cutaneous melanoma is one of the most feared cancers worldwide due to resistance to treatments and the high capacity to develop metastases. Photodynamic therapy (PDT), a minimally invasive therapeutic modality, is a promising ...