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Estudos sobre a síntese de ftalocianinas anfifílicas com baixa agregação em solução
(Universidade Federal de São Carlos, 2013-01-16)
The present dissertation describe the studies conducted on the synthesis and photophysical properties of phthalocyanine dyes. The main propose of this work was to produce amphiphilic structures with low aggregation in ...
Síntese de clorinas anfifílicas com potenciais aplicações em terapia fotodinâmica
(Universidade Federal de São Carlos, 2012-10-26)
The main objective of this work was to construct amphiphilic chlorins with low aggregation in a physiological environment. The synthesis and structural characterization of the target compounds were carried out, and preliminary ...
Estudo fitoquímico de Conchocarpus marginatus (Rutaceae), e avaliação do potencial biológico dos compostos isolados
(Universidade Federal de São Carlos, 2013-03-27)
The specie Conchocarpus marginatus is native from Espírito Santo. This plant, that was recently reclassified by PIRANI e KALLUNKI, does not show chemical or biological data in literature yet. In this way, the phytochemical ...
Estudo da atividade biológica do motivo ECD do domínio tipo-desintegrina da botropasina
(Universidade Federal de São Carlos, 2011-05-10)
Integrins are cell surface receptors that mediate cell adhesion and platelet aggregation, although they do part of important physiological processes in the organism, are also related pathologies such as tumorigenesis, ...
Emprego da organocatálise como uma ferramenta da química verde em reações de adição conjugada : estudos visando a síntese de anéis indólicos
(Universidade Federal de São Carlos, 2012-03-30)
Organocatalysis has emerged as a powerful synthetic paradigm and has accelerated the development of new methods to make diverse chiral molecules. In addition, the small chiral organic molecules used to accelerate asymmetric ...
Planejamento de inibidores da cruzaína baseado em fragmentos
(Universidade Federal de São Carlos, 2011-07-27)
The Chagas disease, described in 1909 by the Brazilian sanitary physician, scientist and bacteriologist Dr. Carlos Chagas, is caused by the Trypanosomatid parasite Trypanosoma cruzi. Current treatments involve the use of ...
Atividade inseticida de espécies de trichilia frente à lagarta-do-cartucho do milho spodoptera frugiperda
(Universidade Federal de São Carlos, 2008-07-18)
This work presents the phytochemical study and biological assays carried out with organic extracts of fruits and seeds
from Trichilia claussenii, T. elegans and inflorescence from T. catigua against S. frugiperda. Among ...
Estudo químico e biológico de micro-organismos endofíticos associados às frutas banana, pêra e goiaba
(Universidade Federal de São Carlos, 2010-03-05)
Studies about interaction between microorganisms and plants are focused mainly in the vegetal tissues like roots, steam and leaves. Fruits are a right target for microorganism attacks. Nevertheless, endophytic microorganisms ...
Estudo fitoquímico de Rauia sp e atividades sobre formigas cortadeiras e sobre a lagarta-do-cartucho do milho
(Universidade Federal de São Carlos, 2009-09-11)
The control of agriculture plague is relevant to Brazil that has large crop area. The control, by natural product, generally low toxic to humans and to animals and specific to target plague, is recommended. This work ...
Ensaios bioquímicos e celulares para a identificação de novos inibidores de TcGAPDH seletivos à HsGAPDH
(Universidade Federal de São Carlos, 2011-08-11)
Chagas disease is a tropical neglected illness; nearly 10 million people are infected, in 2008 it was responsible for the deaths of about 10 thousand people. At present, only two medicines (benznidazol and nifurtimox) are ...