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Telurooxetanas: estudos cristalográficos, modelagem molecular e cálculos de docking para aplicação biológica
(Universidade Federal de São Carlos, 2009-02-10)
This work is composed of 4 chapters. In Chapter 1 is a description of the problems addressed here, starting with the characteristics of the protein, its biological and social importance, and the interactions responsible ...
Estudos estruturais de compostos de telúrio e de docking em catepsinas B, K, L, S
(Universidade Federal de São Carlos, 2013-03-28)
Cathepsins are lysosomal cysteine proteases responsible for protein turnover in our organism. In non-lysosomal environment they are related to a number of diseases such as cancer, Alzheimer, autoimmune diseases and ...