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Complexos semi-sanduíche de RuII/areno e produtos naturais: uma promissora combinação para novos metalofármacos
(Universidade Federal de São Carlos, 2020-10-15)
This thesis presents the synthesis, characterization and evaluation of antitumor activity of nineteen neutral and monocatonic organometallic complexes containing ligands derived from natural products. The complexes were ...
Influência do grupo carboxílico na atividade citotóxica e na interação de novos complexos de rutênio com DNA e HSA
(Universidade Federal de São Carlos, 2016-02-25)
The purpose of this work is evaluate how the position of a free carboxyl group can affect the interaction with DNA and HSA, and the cytotoxic profile against tumor and normal cells and Mycobacterium tuberculosis, for a set ...