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Análises de compostos orgânicos não específicos no esgoto sanitário doméstico através das técnicas RMNq e HPLC-(UV/MS)-SPE-ASS-NMR
(Universidade Federal de São Carlos, 2014-10-10)
The growth of industrial deployment and urbanization play a major role in the degradation of global environmental and resource depletion mainly in countries in development such as Brazil. The problems regarding water ...
Estudos sobre a síntese de ftalocianinas anfifílicas com baixa agregação em solução
(Universidade Federal de São Carlos, 2013-01-16)
The present dissertation describe the studies conducted on the synthesis and photophysical properties of phthalocyanine dyes. The main propose of this work was to produce amphiphilic structures with low aggregation in ...
Síntese de clorinas anfifílicas com potenciais aplicações em terapia fotodinâmica
(Universidade Federal de São Carlos, 2012-10-26)
The main objective of this work was to construct amphiphilic chlorins with low aggregation in a physiological environment. The synthesis and structural characterization of the target compounds were carried out, and preliminary ...
Estudo químico de plantas do gênero Hortia, do fungo Guignardia citricarpa e avaliação de seus potenciais efeitos biológicos
(Universidade Federal de São Carlos, 2011-10-26)
The chemical investigation of plants belonging to the genus Hortia described here aimed at contributing to the chemosystematics of the family Rutaceae as well as to the correct placement of this genus within this family. ...
Applications of NMR techniques: Hyphenations (LC-SPENMR), affinity (DOSY) and NOE based (STD and Tr-OESY) to probe the binding interactions of ligands (synthetic and natural) towards protein
(Universidade Federal de São Carlos, 2014-01-17)
O foco principal desse trabalho foi a implementação, otimização e aplicações práticas de métodos de ressonância magnética nuclear (RMN) com o propósito de avaliar as interações entre moléculas de diferentes massas molares, ...
Estudo fitoquímico de Conchocarpus marginatus (Rutaceae), e avaliação do potencial biológico dos compostos isolados
(Universidade Federal de São Carlos, 2013-03-27)
The specie Conchocarpus marginatus is native from Espírito Santo. This plant, that was recently reclassified by PIRANI e KALLUNKI, does not show chemical or biological data in literature yet. In this way, the phytochemical ...
Estudo químico do fungo Colletotrichum acutatum e sua interação com Citrus sinensis
(Universidade Federal de São Carlos, 2014-11-06)
Brazil remains the world's largest orange producer, accounting for 32% of the total production of oranges and 50% orange juice. The State of São Paulo holds 97% of Brazilian exports of orange juice, possessing one of the ...
Integração de métodos in silico e in vitro para o planejamento de inibidores da enzima cruzaína
(Universidade Federal de São Carlos, 2011-06-30)
Chagas disease, caused by the flagellate protozoan of the family Trypanosomatidae Trypanosoma cruzi, is endemic in Latin America. The available drugs are ineffective and cause severe side effects. Therefore, it is necessary ...
Síntese e avaliação da atividade biológica de compostos N-Heterocíclicos
(Universidade Federal de São Carlos, 2011-07-28)
N-heterocyclic compounds have a large number of biochemical and medical applications and an important role in the discovery of new drugs, and many of best sellers, currently in use, contains one or more N-heterocyclic ...
Ressonância magnética nuclear ultrarrápida: implementação, desenvolvimento e aplicações
(Universidade Federal de São Carlos, 2011-11-24)
This work highlights the implementation, development and application of the Ultrafast Nuclear Magnetic Resonance (UFNMR) technique, proposed by Frydman and co-workers. Through this technique, it is possible to perform ...