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Planejamento e avaliação de fragmentos moleculares como inibidores da enzima cruzaína
(Universidade Federal de São Carlos, 2015-08-24)
The available drugs for treating Chagas disease are not
effective, therefore the development of new therapies is needed. Cruzain is the major
Trypanosoma cruzi cysteine protease, the causative agent of the disease, and ...