Browsing Genética Evolutiva e Biologia Molecular - PPGGEv by Subject "TRAIL"
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Potencial antitumoral das proteínas TRAIL e IL-2 expressas e veiculadas por Salmonella Typhimurium atenuada em modelo de câncer colorretal
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, Câmpus São Carlos, 14/10/2019)Colorectal cancer is the third most diagnosed malignant disease and the fourth leading cause of cancer-related deaths in the world. Cancer treatments are not fully effective and low selectivity to tumor tissue has marked ... -
Imunoterapia com IL-2 e TRAIL expressas por Salmonella recombinante contra o câncer de bexiga
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, Câmpus São Carlos, 19/12/2022)IL-2 and TRAIL are therapeutic agents known for their antitumor role, but they can be rapidly cleared by the body or be toxic, compromising their function. To reverse this impasse, the synthesis of these agents by living ...