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Efeito do mentol e da mentona e sua complementação ao praziquantel no processo inflamatório durante a esquistossomose murina
(Universidade Federal de São Carlos, 2018-02-28)
Schistosomiasis is an infectious disease caused by helminths of Schistosoma genus. Around 206 million people worldwide are infected and 200,000 die. In Brazil, only S. mansoni is found and causes mansonic schistosomiasis. ...
Estudos genético-populacionais em Astyanax aff. Scabripinnis da região da Serra da Mantiqueira
(Universidade Federal de São Carlos, 2018-10-19)
Genetic studies of natural populations have long been helping the scientific community and society in general to understand the evolution and conservation of both environments and communities. These studies have helped to ...
Degradação de matéria orgânica terrestre por microrganismos do rio Amazonas – Metagenômica e genômica populacional
(Universidade Federal de São Carlos, 2018-12-14)
Microbes from Amazon river basin represent an unexplored biodiversity, with a huge metabolic potential. This ecosystem receives large amounts of terrestrial organic matter (OM), which promotes heterotrophic microbial growth. ...
Efeito do nocaute da mitofusina 2 sobre a mitocôndria, o retículo endoplasmático e a mitofagia em oócitos murinos
(Universidade Federal de São Carlos, 2018-08-24)
Mitofusins 1 (MFN1) and 2 (MFN2) are transmembrane GTPases present in the outer mitochondrial membrane and involved in the regulation of mitochondrial fusion. Since MFN2 is also present in the membrane of the endoplasmic ...
Aspectos filogeográficos de Leporinus cf. friderici e da distribuição da diversidade genética em Leporinus cf. friderici Paraná e Megaleporinus obtusidens na bacia do Alto Paraná
(Universidade Federal de São Carlos, 2018-10-05)
The megadiversity of the Neotropical ichthyofauna has been associated to recent diversification processes, reflecting in subtle or lacking morphological differentiation between species, challenging the classical taxonomic ...
Efeito das enzimas recombinantes de Schistosoma mansoni Hipoxantina-Guanina Fosforibosiltransferase (HGPRT) e Purina Nucleosídeo Fosforilase (PNP) no tratamento da esquistossomose experimental
(Universidade Federal de São Carlos, 2018-02-26)
Schistosomiasis is a disease that affects a large number of people in 78 countries. The
number of cases has increased in recent years and there is no vaccine and new drugs, a
worrying aspect, since there is loss of ...
Evolução e integração de fenótipos complexos em insetos: estudo de caso em Teleopsis Dalmanni (Diptera:Diopsidae) e em espécies de Anastrepha do grupo Fraterculus (Diptera: Tephritidae)
(Universidade Federal de São Carlos, 2018-08-31)
Complex traits are affected by multiple traits and processes, whose interaction shape and determine their evolutionary patterns. This work uses quantitative evolutionary genetic methodologies to understand the evolutionary ...
Clonagem e expressão heteróloga de proteínas estruturais (C, prM, E) de Zika Virus (ZIKV)
(Universidade Federal de São Carlos, 2018-08-31)
Viruses are organisms which depend on the host cellular machinery to replicate,
and are relevant to human, livestock and plant health. The modern threat of emerging
pandemics is pressing and, in this scenario, Zika Virus ...
Caracterização fenotípica e molecular dos mecanismos de resistência aos beta-lactâmicos em linhagens clínicas de Klebsiella pneumoniae isoladas do Amazonas
(Universidade Federal de São Carlos, 2018-10-25)
Klebsiella pneumoniae resistant to beta-lactams are present in hospitals worldwide and reduce treatment alternatives. In this study, 40 K. pneumoniae isolates were characterized. All of them were resistant to beta-lactam ...
Estudos comparativos da interação de Hsp90 de diferentes organismos com nucleotídeos adenosina e caracterização da Aha4 de Plasmodium falciparum
(Universidade Federal de São Carlos, 2018-07-31)
Hsp90 (heat shock protein of 90 kDa) are among the most abundant proteins in non-stressed cells. They interact with proteins that are not in the native state, correcting their incorrect folding, they participate in signal ...