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Identificação de ligantes e substratos do complexo E3 ubiquitina-ligase SCF(FBXL17)
(Universidade Federal de São Carlos, 2022-02-10)
Fbxl17 is one of the 69 F-box (Fbx) proteins in humans capable of interaction with SKP1,
Cullin 1 and Rbx1 to form the E3 ubiquitin ligase complex SCF(Fbxl17). The SCF(Fbxl17)
complex is the major class of human E3 ...
Cistatinas de maqui: produção recombinante e inibição de cisteíno peptidases
(Universidade Federal de São Carlos, 2022-02-15)
Cystatins are tight binding competitive inhibitors of cysteine peptidases. In plants, they act regulating different physiological mechanisms, as well as defending from biotic and abiotic stresses, making them of potential ...
Evolução molecular e padrões de expressão de genes da família das proteínas ligantes a odores (OBPs) em duas espécies de moscas-das-frutas do grupo Anastrepha fraterculus
(Universidade Federal de São Carlos, 2016-04-18)
Odorant-binding proteins (OBPs) are of great importance for survival and reproduction
since they participate in initial steps of the olfactory signal transduction cascade,
solubilizing and transporting chemical signals ...
Evolução molecular da família gênica dos receptores de odores e proteínas ligantes a feromônios e genética de populações de genes quimiossensoriais em espécies de Anastrepha do grupo fraterculus
(Universidade Federal de São Carlos, 2016-05-02)
This dissertation is divided into three chapters. In the first chapter, we provide a concise
literature review that discusses key theoretical concepts, the rationale, and main objectives
outlined for this study. The ...
Enriquecimento ambiental e a modulação da emocionalidade, cuidado materno e metilação de genes em camundongos fêmeas LG/J
(Universidade Federal de São Carlos, 2022-08-30)
Environmental Enrichment (EE) can be considered as a set of environmental changes that can adjust the model of a species and favor well-being in captive animals. The present study intends to investigate the influence of ...
Caracterização da diversidade e estrutura genética de uma população invasora e investigação de possíveis híbridos entre as espécies ameaçadas Leontopithecus rosalia e Leontopithecus chrysomelas
(Universidade Federal de São Carlos, 2022-10-28)
The introduction of non-native species is an event that can jeopardize the conservation of native species. The introduction of alien species is usually based on a few individuals and is linked to impacts related to the ...
Evolução molecular dos genes doublesex e fruitless em moscas-das-frutas do grupo Anastrepha fraterculus (Diptera, Tephritidae)
(Universidade Federal de São Carlos, 2009-07-31)
Species of the Anastrepha fraterculus group are one of the most important agricultural pest from South America and form a group of closely related species whose identification is very difficult. It is problematic to establish ...
Potencial antitumoral das proteínas TRAIL e IL-2 expressas e veiculadas por Salmonella Typhimurium atenuada em modelo de câncer colorretal
(Universidade Federal de São Carlos, 2019-10-14)
Colorectal cancer is the third most diagnosed malignant disease and the fourth leading cause of cancer-related deaths in the world. Cancer treatments are not fully effective and low selectivity to tumor tissue has marked ...
QTLs associados com emocionalidade em fêmeas pós-parto de camundongos LG/J x SM/J
(Universidade Federal de São Carlos, 2012-02-14)
In mammals, newborns need parental care, mostly maternal care, to succeed in development. Mother emotionality may affect development at initial stages or even emotionality of the offspring in adulthood. In the present study ...
Filogeografia comparada e preditiva na divisão leste-oeste do Cerrado: teste de divergência simultânea e identificação de características preditoras de quebra filogeográfica
(Universidade Federal de São Carlos, 2022-09-02)
The Cerrado is a vast savanna formation in central Brazil currently included in the list of the main global hotspots for biodiversity conservation. Despite the recognition of its biological relevance, the biogeographic ...