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Desenvolvimento de um banco de dados de SNPs humanos relacionados a doenças virais
(Universidade Federal de São Carlos, 2022-07-27)
Viruses are agents that can cause several human diseases, but the individual response can be distinct. Genetic factors can affect the susceptibility and host therapy response to certain viral diseases. The research for ...
Análise da expressão gênica e conteúdo proteico de ABCB10, APEX1 e HMGB1 em pacientes com beta talassemia maior e intermediaria
(Universidade Federal de São Carlos, 2017-09-04)
Beta thalassemias (BT) are a group of hereditary diseases characterized by the partial or total suppression of beta globin chains synthesis. Clinically, it manifests itself in three distinct forms: minor (BTm), intermedia ...
Estudo sobre a expressão da metaloproteinase de matriz 7(MMP-7), a infecção pelos vírus HPV e EBV e o grau de malignidade de lesões do colo uterino
(Universidade Federal de São Carlos, 2016-04-20)
Cervical cancer is the second largest cause of deaths from malignant cancer
among women worldwide. Many studies show the importance of the HPV virus
in the onset of cervical cancer, but because of the monoclonal nature ...
Estudos transcricionais em leucócitos de portador da síndrome de Down, através da técnica de análise serial da expressão gênica (SAGE).
(Universidade Federal de São Carlos, 2004-01-22)
Estudos funcionais e estruturais da proteína recombinante humana UBE2G2 (Ubiquitin-conjugating enzyme E2G2).
(Universidade Federal de São Carlos, 2005-06-10)
The ubiquitin system represents a selective mechanism for intracellular
proteolysis in eukaryotic cells that involves the sequential activity of three
enzymes, E1 (Ubiquitin activating enzyme), E2 (Ubiquitin-conjugating
enzyme), ...
A integrina a2b1 na progressão tumoral mamária: papel no microambiente tumoral e na metástase
(Universidade Federal de São Carlos, 2019-08-23)
The harmonic functioning of cells involves an orchestrated synchronization of signaling that maintains the balance between proliferation and cell death in healthy tissues. Eventually, gene mutations can occur and the ...
Efeito do tratamento com hidroxiureia sobre a expressão gênica de ATF4, MSN, PBXIPI e SNCA em pacientes com anemia falciforme e em células K562
(Universidade Federal de São Carlos, 2020-03-06)
Our study aimed to analyze the expression and protein content of four genes (ATF4, MSN, PBXIP1 and SNCA) by qPCR and Western Blotting in individuals with sickle cell anemia treated and not treated with hydroxyurea (HU) in ...