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Expressão recombinante e ensaios de atividade de duas thaumatin-like proteins do Maqui (Aristotelia chilensis)
(Universidade Federal de São Carlos, 2022-10-24)
Thaumatin-like Proteins (TLP) are members of the Pathogenesis-Related Proteins family 5 (PR-5), and are present in fungi, plants and invertebrates. In plants, these proteins are involved both in the host’s defense, often ...
Caracterização funcional e bioquímica do fator de transcrição rlmA e da interação de PkcA e Hsp90 no fungo Aspergillus fumigatus
(Universidade Federal de São Carlos, 2017-12-18)
Aspergillus fumigatus is an opportunistic human pathogen that causes systemic infections, including invasive pulmonary aspergillosis in immunocompromised individuals. Survival of this fungus is highly dependent on the cell ...
Clonagem e expressão heteróloga de proteínas estruturais (C, prM, E) de Zika Virus (ZIKV)
(Universidade Federal de São Carlos, 2018-08-31)
Viruses are organisms which depend on the host cellular machinery to replicate,
and are relevant to human, livestock and plant health. The modern threat of emerging
pandemics is pressing and, in this scenario, Zika Virus ...
Validação de kit imunocromatográfico rápido para diagnóstico da Hepatite C
(Universidade Federal de São Carlos, 2019-09-17)
Hepatitis C is an infectious disease caused by the Hepatitis C Virus (HCV) and usually asymptomatic in the acute phase. Globally, an estimated 71 million people are infected with HCV and approximately 400,000 deaths happen ...
Efeito citotóxico e pró-apoptótico do composto [6]-Shogaol contra células de câncer de bexiga (MB49), in vitro
(Universidade Federal de São Carlos, 2021-05-24)
Bladder cancer is considered one of the most aggressive malignancies due to its profile of recurrence and progression, and even with the improvement in methods of diagnosis and treatment, the mortality rate has not shown ...
Expressão, purificação e caracterização das luciferases de Cratomorphus distinctus (Lampyridae) e Euryopa clarindae (Phengodidae) e sondagem de suas aplicabilidades
(Universidade Federal de São Carlos, 2024-08-02)
Luciferases are the enzymes that catalyze the bioluminescence reaction in organisms
such as beetles. Bioluminescence has been used for bioanalytical purposes for
decades, including ATP detection assays, enzymatic assays, ...