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Derivação de células tronco pluripotentes induzidas a partir de pacientes com doenças mitocondriais como modelo de estudo da herança mitocondrial
(Universidade Federal de São Carlos, 2015-11-30)
Mitochondrial dysfunctions caused by mutations in the mitochondrial DNA (mtDNA) represent an important group of human pathologies. However, it is not possible to predict with accuracy the risk of a woman with mutant mtDNA ...