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Análise toxicológica da nanopartícula de óxido de ferro misto (NP Fe3O4) com ligantes de sulfonato de sódio (SO3)-Na+): in vitro e in vivo
(Universidade Federal de São Carlos, 2022-10-25)
Known for their biocompatible potential and magnetic property, iron oxide nanoparticles are the target of several studies for different applications. However, the synthesis of new nanoparticles with different physicochemical ...
Expressão recombinante e ensaios de atividade de duas thaumatin-like proteins do Maqui (Aristotelia chilensis)
(Universidade Federal de São Carlos, 2022-10-24)
Thaumatin-like Proteins (TLP) are members of the Pathogenesis-Related Proteins family 5 (PR-5), and are present in fungi, plants and invertebrates. In plants, these proteins are involved both in the host’s defense, often ...
Expressão recombinante de endo-beta-1,4 xilanase identificada no meta-transcriptoma de cupins da espécie Heterotermes tenuis para produção de bioetanol
(Universidade Federal de São Carlos, 2022-02-22)
The search for alternative energy sources to the consumption of petroleum and the attention to the environment has awakened the use of new bases in biofuels. In line with this is second-generation ethanol (E2G), which can ...
Efeito citotóxico e pró-apoptótico do composto [6]-Shogaol contra células de câncer de bexiga (MB49), in vitro
(Universidade Federal de São Carlos, 2021-05-24)
Bladder cancer is considered one of the most aggressive malignancies due to its profile of recurrence and progression, and even with the improvement in methods of diagnosis and treatment, the mortality rate has not shown ...
Análise dos transcriptomas de Paspalum notatum Flúggé e Paspalum vaginatum Swartz em condição de déficit hídrico
(Universidade Federal de São Carlos, 2020-02-19)
Drought is one of the abiotic stresses that most affect plant growth and productivity. Grasses of the genus Paspalum are used successfully in pastures and lawns, and some ecotypes of Paspalum notatum (bahiagrass) have good ...
Clonagem e caracterização das isoformas de luciferases de lanternas e corpo gorduroso do vagalume Aspisoma lineatum (Lampyridae: Cratomorphini): origem estrutural e evolutiva das luciferases pH-sensitivas mais eficientes à partir de ancestrais pH-insensitivas
(Universidade Federal de São Carlos, 2020-10-31)
Firefly luciferases emit yellow-green light with high efficiency at physiological pH. However, under acidic conditions, in the presence of heavy metals or high temperatures, they emit red light. To understand the structural ...
Estudo dos efeitos antiangiogênicos da desintegrina-símile Alternagina-C (ALT-C) em células endoteliais (HUVEC), tendo como alvo a integrina α2β1
(Universidade Federal de São Carlos, 2020-03-04)
Angiogenesis is a crucial process in tumor progression, and it is mainly regulated by the vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. Studies have shown that VEGF/VEGFR2 axis signaling is directly ...