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Investigação dos mecanismos envolvidos na herança mitocondrial: o papel da dinâmica mitocondrial
(Universidade Federal de São Carlos, 2020-10-08)
Diseases caused by mutations in mitochondrial DNA (mtDNA) are the most common genetic diseases in humans. Despite this, there is no effective treatment for these diseases and the mechanisms of inheritance are not fully ...
Cistatinas de cana-de-açúcar: produção recombinante em vacúolos de cana-de-açúcar transgênica (e outros sistemas de expressão em plantas) e estudos de interação com uma pseudo protease do coleóptero Sphenophorus levis
(Universidade Federal de São Carlos, 2021-03-29)
Sphenophorus levis (Curculionidae: Coleoptera) is one of the major pests of sugarcane crop in Brazil and presents cysteine proteases as main digestive enzymes. In this project, we report the characterization of Sl-CathL-CS, ...
Nova proposta didática para o ensino de biologia molecular na educação básica
(Universidade Federal de São Carlos, 2022-04-07)
The teaching of science and biology in basic education aims to provide minimum content so that individuals can deal with new information and are able to understand, question and position themselves in the face of ethical ...
Avaliação de três nanopartículas funcionais com atividade citotóxica para o tratamento do câncer de Bexiga
(Universidade Federal de São Carlos, 2022-04-20)
Bladder cancer is considered one of the most frequent neoplasms in the world. Although chemotherapy, surgery, immunotherapy and therapy have been accepted and practical methods for decades, they may not respond to due to ...
Identificação de ligantes e substratos do complexo E3 ubiquitina-ligase SCF(FBXL17)
(Universidade Federal de São Carlos, 2022-02-10)
Fbxl17 is one of the 69 F-box (Fbx) proteins in humans capable of interaction with SKP1,
Cullin 1 and Rbx1 to form the E3 ubiquitin ligase complex SCF(Fbxl17). The SCF(Fbxl17)
complex is the major class of human E3 ...
Caracterização fisiológica e avaliação do transcriptoma de linhagens de Saccharomyces cerevisiae termotolerantes isoladas durante a produção industrial de etanol
(Universidade Federal de São Carlos, 2022-12-02)
The use of thermotolerant yeast strains can improve productivity in the ethanol production process, allowing fermentation to occur at temperatures above 40°C. This characteristic can benefit, for example, the production ...