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Now showing items 11-20 of 210
Efeito do knockout da Mitofusina 1 sobre a fertilidade de oócitos murinos
(Universidade Federal de São Carlos, 2018-08-31)
Fertility is directly related to oocyte developmental competence. In this context, oocyte mitochondria play a crucial role and have become an important target in assisted reproduction therapies. However, the molecular ...
Efeito modulador do extrato total do Paenibacillus polymyxa RNC-D em macrófagos e Leishmania (Leishmania) amazonensis in vitro
(Universidade Federal de São Carlos, 2018-04-20)
Leishmaniasis is an infection caused by Leishmania gender protozoa. The treatment of the disease is generally problematic, as the drugs used on clinical practice are toxic. One of the paths in the search for new therapeutic ...
SNPs no gene da HSC70 e suas implicações na carcinicultura e conservação dos estoques de camarão-da-amazônia (Macrobrachium amazonicum)
(Universidade Federal de São Carlos, 2013-06-14)
Macrobrachium amazonicum is an endemic species in South America, which has been exploited by artisanal fisheries in northern and northeastern Brazil. The overexploitation of this species has led to the decline of its natural ...
Fitocistatinas: caracterização bioquímica e aplicação na transformação genética de cana-de-açúcar
(Universidade Federal de São Carlos, 2018-02-27)
Cystatins are tight-binding, competitive cysteine-peptidase inhibitors. In plants, these proteins are part of natural defense mechanism, regulating endogenous and exogenous peptidases. In humans, cystatins are responsible ...
Expressão gênica no desenvolvimento adulto de operárias de Frieseomelitta varia
(Universidade Federal de São Carlos, 2018-06-04)
Global declines in pollinators have served as the impetus for the widespread study of hymenopterans. The molecular processes controlling detoxification and antioxidant pathways are of supreme importance to insects that are ...
O efeito da desintegrina DisBa-01 e do silenciamento da integrina avB3 e na interação de células tumorais e endoteliais in vitro
(Universidade Federal de São Carlos, 2013-02-27)
Metastasis depends on several physiological processes such as cell adhesion, transendothelial cell migration and proliferation. These events are mediated mostly by integrins, which are adhesion receptors present on cell ...
Comparação transcricional dos túbulos de Malpighi e corpo gorduroso de Zophobas morio: função de AMP-CoA ligases nos túbulos e relação com lanternas de Arachnocampa luminosa
(Universidade Federal de São Carlos, 2017-10-27)
The Malpighian tubules in insects play an essential role in osmoregulation, performing transport of ions and fluids during the formation of primary urine, whereas fat body is usually associated with the intermediary ...
Efeito do mentol e da mentona e sua complementação ao praziquantel no processo inflamatório durante a esquistossomose murina
(Universidade Federal de São Carlos, 2018-02-28)
Schistosomiasis is an infectious disease caused by helminths of Schistosoma genus. Around 206 million people worldwide are infected and 200,000 die. In Brazil, only S. mansoni is found and causes mansonic schistosomiasis. ...
Análise do transcriptoma da glândula venenífera de Rhinocerophis alternatus (Bothrops alternatus): identificação de metaloproteases e desintegrinas
(Universidade Federal de São Carlos, 2011-03-04)
The desintegrinas are cys-rich polypeptides without enzymatic activity, some found in snake venoms with an adhesive motif to integrin, unleashing distinct responses. Several research groups have been studying snake venom ...
Papel do domínio desintegrina da ADAM9 humana na modulação da migração e invasão de células tumorais
(Universidade Federal de São Carlos, 2011-02-25)
Cancer metastasis is the major cause of death, consequently studies to understand the molecular mechanisms involved in this process are essential to the knowledge of this disease. Cell migration and invasion are part of ...