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Efeitos citotóxicos e genotóxicos de uma nova nanopartícula de titânio de interesse industrial - in vitro
(Universidade Federal de São Carlos, 2020-02-18)
Titanium dioxide nanoparticles (TiO2 NP) are included as one of the most used nanomaterials by industries in general; it is applied in coatings, pigments, and paints for its ability to offer opacity and brightness, in ...
Utilizando ferramentas da genética forense para investigar a origem dos indivíduos do canário-da-terra (Sicalis flaveola) mantidos em cativeiro
(Universidade Federal de São Carlos, 2020-03-31)
Wildlife protection is a global priority issue. International treaties, laws, national entities and organizations fight for the conservation of biodiversity and protection of wildlife, generating environmental awareness ...
Montagem e análise taxonômica-funcional de transcriptomas de espécies de cupins brasileiros
(Universidade Federal de São Carlos, 2020-02-28)
Termites (Isoptera) are eusocial insects that stand out for their hierarchical and structural organization, demonstrating complex social behaviors, numerous symbiotic interactions, and a great potential for bioprospecting ...
Impacto da deleção oócito-específica de Rad51 sobre o DNA mitocondrial e a divisão meiótica em murinos
(Universidade Federal de São Carlos, 2020-02-28)
RAD51 is a protein of eukaryotic organisms, with a central role in the DNA repair pathway by homologous recombination. Its function in the nucleus of somatic cells is well established, being necessary for the maintenance ...
Efeito do tratamento com hidroxiureia sobre a expressão gênica de ATF4, MSN, PBXIPI e SNCA em pacientes com anemia falciforme e em células K562
(Universidade Federal de São Carlos, 2020-03-06)
Our study aimed to analyze the expression and protein content of four genes (ATF4, MSN, PBXIP1 and SNCA) by qPCR and Western Blotting in individuals with sickle cell anemia treated and not treated with hydroxyurea (HU) in ...
Caracterização da antigenicidade e do efeito protetor em modelo murino de proteínas recombinantes de Erysipelothrix rhusiopathiae candidatas a antígenos vacinais
(Universidade Federal de São Carlos, 2020-02-18)
Erysipelothrix rhusiopathiae is a gram-positive, bacilliform, and encapsulated bacterium that
causes swine erysipelas, a disease characterized by skin lesions and other symptoms such
as septicemia, arthritis, and ...
Investigação dos mecanismos envolvidos na herança mitocondrial: o papel da dinâmica mitocondrial
(Universidade Federal de São Carlos, 2020-10-08)
Diseases caused by mutations in mitochondrial DNA (mtDNA) are the most common genetic diseases in humans. Despite this, there is no effective treatment for these diseases and the mechanisms of inheritance are not fully ...