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Papel das integrinas αvβ3 e α5β1 na migração de células de tumor de mama triplo negativo e células endoteliais em hipóxia
(Universidade Federal de São Carlos, 2022-04-14)
Breast tumors show high incidence and mortality for female oncologic cases in 2020. Tumor microenvironment presents several elements, such as extracellular matrix (ECM). ECM proteins bind to cells through receptors such ...
Identificação de ligantes e substratos do complexo E3 ubiquitina-ligase SCF(FBXL17)
(Universidade Federal de São Carlos, 2022-02-10)
Fbxl17 is one of the 69 F-box (Fbx) proteins in humans capable of interaction with SKP1,
Cullin 1 and Rbx1 to form the E3 ubiquitin ligase complex SCF(Fbxl17). The SCF(Fbxl17)
complex is the major class of human E3 ...