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Caracterização fisiológica e avaliação do transcriptoma de linhagens de Saccharomyces cerevisiae termotolerantes isoladas durante a produção industrial de etanol
(Universidade Federal de São Carlos, 2022-12-02)
The use of thermotolerant yeast strains can improve productivity in the ethanol production process, allowing fermentation to occur at temperatures above 40°C. This characteristic can benefit, for example, the production ...
Caracterização funcional e bioquímica do fator de transcrição HsfA e estudo da termotolerância, composição lipídica e integridade da parede celular de Aspergillus fumigatus
(Universidade Federal de São Carlos, 2022-02-02)
The filamentous and saprophytic fungus Aspergillus fumigatus is the main causative pathogen of invasive pulmonary aspergillosis (API) in immunocompromised individuals. One of its most important determinants of virulence ...
Estudos cromossômicos clássicos e moleculares no complexo de espécies Astyanax scabripinnis (Characiformes, Characidae)
(Universidade Federal de São Carlos, 2020-08-26)
Astyanax is a fish genus of Characiformes and currently is classified as incertae sedis. Astyanax scabripinnis, one of these species, is recognized as a species complex, which is composed of 33 species. This study propose ...
Viabilidade de grãos de pólen de espécies de Paspalum após a criopreservação visando seu uso em programas de melhoramento genético
(Universidade Federal de São Carlos, 2020-02-28)
Paspalum is a genus of the Poaceae family, native to America, of which many species have forage potential. The high natural genetic diversity observed in the genus can be used to obtain and launch new cultivars. For ...
Eficácia da instilação de células da linhagem MB49 e gel polimérico termorreversível na imunização contra o carcinoma urotelial de bexiga
(Universidade Federal de São Carlos, 2020-09-24)
Among the various types of malignant neoplasms, those originating in the bladder can be considered highly impactful due to their prevalence and high recurrence rates, demonstrating the importance of studies involving new ...
Investigação dos mecanismos envolvidos na herança mitocondrial: o papel da dinâmica mitocondrial
(Universidade Federal de São Carlos, 2020-10-08)
Diseases caused by mutations in mitochondrial DNA (mtDNA) are the most common genetic diseases in humans. Despite this, there is no effective treatment for these diseases and the mechanisms of inheritance are not fully ...
Avaliação de três nanopartículas funcionais com atividade citotóxica para o tratamento do câncer de Bexiga
(Universidade Federal de São Carlos, 2022-04-20)
Bladder cancer is considered one of the most frequent neoplasms in the world. Although chemotherapy, surgery, immunotherapy and therapy have been accepted and practical methods for decades, they may not respond to due to ...
Genômica populacional do Mico-Leão-Preto (Leontopithecus chrysopygus, Mikan 1823): uma espécie ameaçada de extinção
(Universidade Federal de São Carlos, 2021-12-01)
The species Leontopithecus chrysopygus, endemic to the Atlantic Forest of the state of São Paulo, is considered endangered by the IUCN and IBAMA. It is estimated that currently the free-living population of this species ...
Estratégias para o desenvolvimento de produtos contra o desgaste dentário erosivo por meio da engenharia de película adquirida com CaneCPI-5: translação das ciências básicas para a clínica
(Universidade Federal de São Carlos, 2022-09-30)
Currently, the scientific development of sugarcane-derived cystatin (CaneCPI-5) has gained strength in the control of erosive tooth wear (ETW). However, for this recombinant protein to be commercially used, it is important ...
Papel das integrinas αvβ3 e α5β1 na migração de células de tumor de mama triplo negativo e células endoteliais em hipóxia
(Universidade Federal de São Carlos, 2022-04-14)
Breast tumors show high incidence and mortality for female oncologic cases in 2020. Tumor microenvironment presents several elements, such as extracellular matrix (ECM). ECM proteins bind to cells through receptors such ...