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Modelagem molecular de derivados pirimidínicos e estudos de docking nas enzimas ciclooxigenase 1 e ciclooxigenase 2
(Universidade Federal de São Carlos, 2010-11-23)
In this research molecular docking was used to study enzime-ligand complexes of Cyclooxygenase 1 (COX-1) and Cyclooxygenase 2 (COX-2) with pyrimidine derivatives, aiming at understanding the possible mechanisms of action ...
Docking de herbicidas na glutationa transferase tau4-4 de soja (Glycine max)
(Universidade Federal de São Carlos, 2011-03-30)
This study, based on molecular docking, describes the search for the most favorable conformations when complexes between herbicides, used in soybean cultivation, and an enzyme involved in the detoxification process are ...
Comparação entre histologia e espectroscopia de fluorescência para avaliação de atrofia cutânea induzida por glicocorticóide em ratos
(Universidade Federal de São Carlos, 2010-09-24)
The gold standard for evaluating skin atrophy is the histological study. When compared to the technique of Fluorescence Spectroscopy (FS), histology requires the physical removal of tissue and their processing in the ...
Análise da microbiota associada à ascídia Didemnum granulatum para a produção de metabólitos secundários bioativos
(Universidade Federal de São Carlos, 2010-06-01)
Studies of marine natural products in 20 years of research have revealed a wide variety of molecules with complex structures and hitherto unknown, and potent biological activities. The aims of this study were to isolate ...
Arsênio em amostras de sedimento da microbacia do Ribeirão Guamium, Piracicaba, SP e seu efeito em organismos zooplanctônicos
(Universidade Federal de São Carlos, 2010-09-09)
Arsenic is an essential chemical element for life, although it can be extremely toxic at concentrations slightly above those required for living organisms. In Brazil, generally well-standardized internationally test organisms ...
Efeito da imunização com enzimas recombinantes do metabolismo de nucleotídeos de Schistosoma mansoni sobre o desenvolvimento da esquistossomose mansônica experimental
(Universidade Federal de São Carlos, 2012-08-29)
Schistosimiasis mansoni is a neglected chronic parasitic disease that affects thousands of people worldwide, caused by the trematode Schistosoma mansoni. In the infected host the disease is characterized by the presence ...
Avaliação do efeito do extrato etanólico bruto de Harpagophytum procumbens em camundongos infectados com Toxocara canis
(Universidade Federal de São Carlos, 2012-02-29)
The Syndrome of Visceral Larva Migrans (VLMS) is a parasitic disease caused by Toxocara canis, one of the most common helminthes in dogs. In the definitive hosts are present in different morphological forms, embryonated ...
Caracterização estrutural e funcional de uma xiloglucanase de Xanthomonas campestris
(Universidade Federal de São Carlos, 2013-07-25)
Xyloglucanases (Xghs) are important enzymes involved in xyloglucan modification and degradation. Xanthomonas campestris (Xcc) is a phytopathogenic bacterium which produces a large number of glycosyl hydrolases (GH), but ...
Morfoanatomia do fruto de açaí em função do teor de água utilizando microscopia óptica e microtomografia de raios-X
(Universidade Federal de São Carlos, 2010-06-18)
Tendo em vista a escassez literária referente a frutos de açaí (Euterpe oleracea - Mart.), este trabalho foi desenvolvido com ênfase anatômica, recorrendo a técnicas usuais de microscopia de luz e microtomografia de raios-X. ...
Expansão de células mesenquimais estromais em frasco spinner e avaliação de aditivos para diminuir a aglomeração de microcarregadores
(Universidade Federal de São Carlos, 2013-04-29)
The increasing interest in the employment of multipotent mesenchymal stromal cells (MSCs) to applications in tissue engineering and cell therapy is mainly attributed to their plasticity and regenerative capacity. The MSCs ...