ListarQuímica - PPGQ por tema "Organocatálise"
Mostrando ítems 1-7 de 7
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Exploração da organocatálise na síntese de intermediários de compostos com potencial biológico
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, , 28/03/2013)In recent decades the use of small molecules acting as catalyst has emerged as a powerful tool to the synthesis of new molecules which have potential biological application. This new model of catalysis provides others ... -
Asymmetric induction on isocyanide-based transformations: development of stereoselective Ugi-type reactions
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 26/05/2023)The design of new synthetic transformations that rapidly allow construction of structurally complex molecules from simple starting materials under both concepts of diversity and function-oriented syntheses is extremely ... -
Síntese de derivados de chalconas e de 2-quinolinonas visando a busca por inibidores das enzimas cruzaína e da família BET bromodomain
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, , 12/09/2014)The first part of this work involved the synthesis of chalcone derivatives towards the development of inhibitors of the enzyme cruzain from Trypanosoma cruzi. Different green chemistry approaches were employed to functionalize ... -
Reações de adição conjugada de indóis e oxindóis empregando organocatálise
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, , 07/08/2014)Organocatalysis has emerged as a powerful synthetic tool which accelerated the development of new methods to obtain symmetric and asymmetric molecules. Furthermore, the use of small organic molecules such as amino acids ... -
Sintese e avaliação de peptidomiméticos contendo heterociclos de três membros como inibidores de catepsina L
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 01/12/2017)Cathepsin L is a lysosomal cysteine protease, that is related to many physiological processes, however overexpression and up- or downregulation may cause several pathologies. Therefore, cathepsin L became an interesting ... -
Adição de Michael de α,α-Diciano-Olefinas a Chalconas via organocatálise assimétrica empregando solvente derivado de biomassa
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 18/05/2018)In recent years, organocatalysed reactions have become an important field in asymmetric synthesis. Particularly, Michael addition reactions using various donors and acceptors have been explored to generate substrates that ... -
Organocatálise assimétrica e sistemas vinílogos: adição de 1,3-oxazolina-2-tionas a aldeídos a,b-insaturados
(Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, Câmpus São Carlos, 16/03/2017)The use of organic molecules in stereoselective transformations has emerged as a powerful tool for the efficient construction of chiral skeletons and complementing existing methods. Currently, a great variety of reactions ...