Browsing Química - PPGQ by Subject "Trypanosoma cruzi"

Now showing items 1-3 of 3

    • Busca de produtos naturais como inibidores específicos de enzimas 

      Severino, Richele Priscila (Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, , 24/10/2008)
      The present work describes the search of bioactive secondary metabolites isolated from plants, against enzymes: gGAPDH (glyceraldehydes-3- phosphate dehydrogenase from Trypanosoma cruzi and lysosomal cathepsins K, V, L and ...

    • Estudo computacional da enzima gGAPDH do Trypanosoma cruzi 

      Oliveira, Osmair Vital de (Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, , 05/06/2009)
      Theoretical methods in computational chemistry were used to study the gGAPDH enzyme from Trypanosoma cruzi. This protozoan is responsible by the Chagas diseases. Molecular dynamics simulations were performed to obtain the ...

    • Integração de métodos in silico e in vitro para o planejamento de inibidores da enzima cruzaína 

      Wiggers, Helton José (Universidade Federal de São Carlos, UFSCar, Programa de Pós-Graduação em Química - PPGQ, , 30/06/2011)
      Chagas disease, caused by the flagellate protozoan of the family Trypanosomatidae Trypanosoma cruzi, is endemic in Latin America. The available drugs are ineffective and cause severe side effects. Therefore, it is necessary ...