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Integração de padrões organizacionais e de processo ao método ágil Scrum
(Universidade Federal de São Carlos, 2006-05-17) Costa Filho, Edes Garcia da; Penteado, Rosângela Aparecida Dellosso; https://lattes.cnpq.br/4061946080136286
Due to the increasing importance of software in society, the software engineering area has devoted continuous effort to improve the software products development process. Today, even with the technological progress, organizations are facing problems to build software within establishing time and costs. Organization and process patterns supply proven solutions to recurring software development process. These pattern categories allow reuse in higher abstract levels, that is, in organizational and process levels. However, else than improve and organize the software development process, organizations must speed up that process to attend market demands. Agile development methods such as Scrum and Extreme Programming (XP) are being often utilized due to the proposal of delivering quality software in less time. In that context, this paper proposes an organized form to use organizational and process patterns together with the Scrum agile method, to allow its extension or adaptation according to the needs of the organization that will use it. Based in use experience and using the SPEM metamodel, phases of integration of organizational and process patterns to Scrum have been proposed and used to create a Scrum extension. Scrum, as other agile methods, presents some weak points that need alternatives to improve them. So, using the phases devised, some organization and process patterns have been integrated to Scrum in order to deal with questions not approached by it. The result of a pilot evaluation study conducted to verify the advantages of that integration and of the SPEM modeling, has indicated the convenience to do them. After the application of the integration phases with some patterns and Scrum, the possibility of guidelines creation to integrate organizational and process patterns to other agile methods has been noted.
Estudo fitoquímico de Rauia sp e Conchocarpus macrophyllus (Rutaceae) e avaliação da atividade antiparasitária de extratos e substãncias isoladas
(Universidade Federal de São Carlos, 2006-05-17) Albarici, Tatiane Regina; Vieira, Paulo Cezar; https://lattes.cnpq.br/8923844563320377; https://lattes.cnpq.br/2400181407309870
This work involved the study of plant extracts of the Rutaceae species. Among 16 extracts tested in assays carried out with T. cruzi gGAPDH and L. tarentolae APRT enzymes and trypomastigote forms of T. cruzi, four showed significant activities at least in one of them. The petroleum ether extract of stems of Conchocarpus macrophyllus (CMCF) and the methanolic extract of leaves of Rauia sp (RFM) showed 94% and 75% of parasitic lyses on trypomastigote forms of T. cruzi. The methanolic extract of leaves of Rauia sp1 (RF1M) showed 74% of inhibition of gGAPDH enzyme and the dichloromethane extract of stems of Conchocarpus macrophyllus (CMCD) showed 74% of inhibition of APRT enzyme. The methanolic extract of leaves of Rauia sp1 (RF1M) showed 67,9% of inhibition on the APRT enzyme assay. The phytochemical study of Rauia sp allowed the isolation of 30 substances among them 4 are described for the first time, the coumarins 3-ethylrauianin and 5-methoxyrauianin and the alkaloids 7-hydroxy-8-methoxy-N-methylflindersine and 8- hydroxy-Nmethylflindersine that is described as a natural product at first time. Among them 26 have already been described in the literature the coumarins murranganone, 7- methoxy-8-(2-acetyloxy-3-methyl-1-oxobut-2-enyl)-coumarin, isomurranganone, murralongin, murrangatin, munomicrolin, murrangatin diacetate, rauianin, umbeliferone e isoescopoletin, the alkaloids N-methyl-4-methoxy-2-quinolone, mirtopsine, dictamine, γ-fagarine, skimmianine, Z-dimethylrhoifolinate, zantobungeanine, zantodioline and veprissine, the amides paprazine and N-transferuloyltyramine, the flavone 3,7,4 -trimethoxy-5-hydroxyflavone, the lignan siringaresinol, the fenolic coumpound vanilic acid and the steroids β-sitosterol and stigmasterol. The phytochemical study of Conchocarpus macrophyllus allowed the isolation of 4 substances the alkaloids arborinine and methylarborinine and the steroids β-sitosterol and stigmasterol. Among the substances tested in one or more assays none of them showed satisfactory results, leading to conclude that either the active compounds have not been isolated or their activity is related to the combination effects.