Browsing by Issue Date, starting with "2008-04-30"

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Análise de mapas conceituais elaborados por alunos da oitava série do ensino fundamental a partir de aulas pautadas na teoria da aprendizagem significativa : a argila como tema de estudo
(Universidade Federal de São Carlos, 2008-04-30)
Lourenço, Ariane Baffa
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Hartwing, Dácio Rodney
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https://lattes.cnpq.br/1241656328850074
In this work we analyze how and where extension student of the eighth series of the basic education of two public schools of the city São Carlos, conceptual maps from theoretical and experimental lessons elaborate, based in the theory of the Significant Learning, having as study subject the material clay. For the accomplishment of the research an initial study of characterization of two types of school clay was made, a white and another red. The results of this study had served as base for the elaboration of the course Clay, given in the regular period of lessons, in real situation of education in room. As instrument of evaluation of the learning reports and text had been used to elaborate by the students, questionnaire and conceptual maps. For the results we had that the use of texts and lessons elaborated based in the theory of the Significant Learning and the use of conceptual maps had assisted the learning of the students. The conceptual map was an efficient tool in the teach-learning process, therefore it allowed the students to identify and to relate the concepts between itself, and with too much concepts and examples, already existing in its cognitive structure, and to get a panorama of as its knowledge was structuralized. For the researcher, the map made possible to identify mistake ideas of the students, being able these to be worked individually, besides serving as evaluation instrument. For the results gotten in this work we evidence that it is possible to the teacher to use conceptual maps in its lessons, because this is a tool that assists in the process of teach-learning of the students, can be used as evaluation instrument and has good acceptance for the students.
Participação da área septal medial nas respostas sialogoga, dipsogênica e cardiovascular induzidas pela pilocarpina
(Universidade Federal de São Carlos, 2008-04-30)
Paulin, Renata Fabris
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Colombari, Débora Simões de Almeida
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https://lattes.cnpq.br/2906710955922416
Peripheral injection of pilocarpine (PILO, 1 mg/Kg of body weight), muscarinic cholinergic agonist, induce salivation, water intake and pressor response. The medial septal area (MSA) is an important brain area involved in cardiovascular regulation and hydroelectrolytic control. In this present study, we investigated: 1) the effect of MSA electrolytic lesion or the blockade of muscarinic cholinergic receptors into MSA on salivation, water intake and cardiovascular responses induced by peripheral pilocarpine; 2) the role of the sympathetic nervous system and/or vasopressin on the cardiovascular responses induced by peripheral pilocarpine; 3) the effect of injection of pilocarpine into MSA on salivation, water intake and cardiovascular responses. Male Holtzman rats weighing 280 to 320 g were submitted to 1 or 15 days MSA electrolytic lesion (2 mA x 5 s) or stainless steel guide cannulas were stereotaxically implanted into the MSA. We observed that peripheral pilocarpine (1 mg/kg of body weight) induces salivary secretion, water intake and an increase in mean arterial pressure (MAP) . This increase in MAP is due to an activation of simpathetic nervous system, since it was significantly reduced by previous treatment with prazosin (1 mg/kg of body weight), but not by vasopressin V1a receptor antagonist (10 µg/kg of body weigh). The salivary secretion and dipsogenic response induced by peripheral pilocarpine was reduced by MSA eletrolytic lesion or MSA muscarinic cholinergic blockade. Nonetheless, the pressor response induced by peripheral pilocarpine was not depend of MSA, since MSA eletrolytic lesion or muscarinic cholinergic receptors blockade did not change this response. Pilocarpine injection into MSA induced water intake (200 e 500 nmol/0,5 µL), salivary secretion (500 nmol/0,5 µL) and MAP increase (500 nmol/0,5 µL). Our results show that peripheral or MSA injection of pilocarpine induce salivary secretion, water intake and pressor response. The pressor response induced by peripheral pilocarpine is due to sympathetic activation. The MSA and its muscarinic cholinergic receptors are involved in the salivary secretion and water intake, but not in the control of pressor response induced by peripheral pilocarpine, suggesting that MSA has a differencial control on the responses induced by peripheral pilocarpine.
Estudo do efeito da Alternagina-C, uma desintegrina do veneno de Bothrops alternatus e de um peptídeo sintético derivado de sua estrutura, sobre a expressão de fatores de crescimento, angiogênese e cicatrização de lesão em pele de rato
(Universidade Federal de São Carlos, 2008-05-07)
Sant'Ana, Estela Maria Correia
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Araújo, Heloísa Sobreiro Selistre de
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https://lattes.cnpq.br/8749163000663076
Angiogenesis and wound repair are mediated by several growth factors that are strictly released. Alternagin-C (ALT-C), a disintegrin-like protein from the venom of Bothrops alternatus induces in vivo angiogenesis as well as the cyclic peptide derived from its primary structure, with the ECD motif (ALT-C PEP). This study investigated the effects of ALT-C and ALT-C PEP on angiogenesis and expression of growth factors in a model of wounded rat skin. The rats were anaesthetized; one cutaneous excision (4 mm diameter) was made on the back of each animal, close to the cervical area. Animals were then divided into 7 groups (five rats/group): control (treated with vehicle); locally treated with 10, 60 and 100 ng ALT-C or 10, 20 and 100 ng ALT-C PEP ALT-C PEP for 1, 3, 5 or 7 consecutive days. At the end of experiments animals were killed, the skin was removed; the cranial portion was used for histological analysis and from the caudal portion; protein were extracted, separated by SDS-PAGE and VEGF, FGF-1, TGFβ1, PDGF, IGF1 e TGFα expression was analyze a by Western blotting. The results show that both, ALT-C and ALT-C PEP induced the formation of new vessels, stimulate collagen synthesis and modulated the expression of growth factors, mainly VEGF and FGF1. The increase in VEGF expression could be detected up to 7 days after injury. FGF1 was also significantly increased, but at a lesser extension than VEGF. In conclusion, we present a protein belonging to the disintegrin group of snake venom toxins stimulates angiogenesis and collagen synthesis in an injured tissue. ALT-C may exert its effects via integrin binding and growth factor modulation. As angiogenesis is an important event for wound healing, ALT-C and ALT-C PEP could be candidates to the development of a new drug for wounded skin repair or regeneration.
A construção da gestão compartilhada da reserva extrativista do Mandira, Cananéia, SP
(Universidade Federal de São Carlos, 2008-05-07)
Cardoso, Thaís Almeida
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Nordi, Nivaldo
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https://lattes.cnpq.br/8168865557947289
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https://lattes.cnpq.br/1975625195000271
This study arose from the proposal of fisheries co-management, based on the sharing of decisions and responsibilities between the State, user groups and other local organizations. The research was developed in the Mandira Extractive Reserve, Cananéia, SP, Brazil, with the objective of contextualizing the way of life and use of resources by the beneficiaries and, using the Research-action, to build up the co-management of the Protect Area. The process was developed by the collective action, of a group of local residents and technicians, looking for the involvement of the other beneficiaries for the effective participation in the management of the Mandira Extractive Reserve. We took as a basis for process analysis the management of the oyster (Crassostrea brasiliana), the main resource used by the local residents, which was frightened by super-exploitation. From the structure of the co-management mechanisms in the Protect Area and of the formulation of simple rules, created in a participative way and contextualized to the local reality, we obtained important results, which involved since the empowerment of the community, in search of autonomy and legitimacy, to the recovery of the stock of the oyster in the Reserve. It is important to emphasize that for the consolidation of this process, making it effective along the time and applicable to other fishing resources used inside the Mandira Extractive Reserve, the strengthening of the local organizations, as well as the implementation of other monitoring mechanisms, with the support of the administrating agency, adopting them as public police, should be maintained.
Efeito do laser de baixa intensidade sobre a regeneração do músculo esquelético em camundongos através da análise de expressão gênica com branched de DNA(bDNA)1
(Universidade Federal de São Carlos, 2008-05-07)
Brasileiro, Olga Sueli Moreira
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Parizotto, Nivaldo Antonio
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https://lattes.cnpq.br/5527703735628408
Estudo do potencial de regeneração natural: uma análise da chuva de sementes e do estrato regenerante da vegetação ciliar na bacia hidrográfica do rio Taperoá, semiárido paraibano, Brasil
(Universidade Federal de São Carlos, 2008-05-12)
Barbosa, Francisca Maria
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Soares, João Juares
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https://lattes.cnpq.br/6093800182799882
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https://lattes.cnpq.br/0156776211731078
It was aimed at to study the natural regeneration in a ciliary area of Caatinga in the basin of the river Taperoá, semi-arid paraibano. The research was accomplished in the january/2004 period the december/2006 and it embraced the riverine area of the stream of Cazuzinha (7º26 13 S and 36º54 30 W; altitude 564-579 m). In that sense, the work understood the following stages: 1) characterization of the composition and of the contribution of the rain of seeds; 2) evaluation of the density, germination and flora of the bank of seeds of the soil in two differentiated stations and 3) analysis of the composition, structures and dynamics of the natural regeneration. In the first stage they were established 102 contiguous parcels of 10 X 10 m (1,02 ha). The collections were accomplished monthly. The collected material was conditioned in paper bags, which were identified with the number of the collector and the portion in the which was located. In the rain of seeds, 6.975 seeds belonging to 80 species were registered. The found density was of 775 seeds/m2/year. It was still verified for the community a pattern of having accentuated seasonality in the seeds production. The herbaceous having been the group that produced most of the sample seeds and the largest wealth of species. Like this, the seeds anemochorics were predominantly dispersed in the dry period. Most of the species zoochorics liberated your fruits in the rainy period, in other words, at that time of better conditions of ripening of the fruit, dispersion and seedling establishment. For the species autochorics the pick of dispersed seeds happened in the dry period. Related to the ecological groups the initial secondary species contributed with the percentile largest of species and liberated seeds. The index of diversity of Shannon was relatively inferior when compared with found for the bank of seeds of the soil. Particularly related to the bank of seeds, it is had that were collected in the 36 raffled parcels, for period amostral (dry and rainy), in each one of these, a sample of soil of 0,25 m2 to the depth of 5 cm. The florístic the identification of the species was based mainly on the morphology of the seedling. The density of the bank was evaluated by the method of seedling emergency. The composition floristc of the bank was represented by 165 species, being the end of the dry and rainy periods represented respectively by 122 and 124 species. The herbaceous ones composed 97% of the seeds germinated in the bank, being 95% in the end of the dry period and 99% in the end of the rainy station. The density of germinated viable seeds was larger in the end of the dry period (877 seeds/m2) than in the end of the rainy station (616 seeds/m2). Like this, it was verified that the end of the rainy period presented the largest wealth of species, however, in the end of the dry period it happened the largest seedling density for area. Does the analysis of the composition, structure and was dynamics of the natural regeneration verified with the distribution of 72 xviii parcels of 1 X 1 m along the course of water, enrolling the woody saplings with height ≥ 0,20 m and DNS < 3 cm. Rose 36 species and 380 individuals in the first inventory and 39 species and 391 individuals in the second. Most of the species belongs to the pioneers' ecological group and secondary initials, being the autochory and animal dispersal the predominant dispersal syndromes. Only three species happened in all the size classes in the two inventories and the largest indexes of natural regeneration were obtained by Croton rhamnifolioides, Combretum pisonioides, an indeterminate specie, Manihot glaziovii and Ziziphus joazeiro. The rates of ingrowths and mortality for the community were 13,8% and 11,3% respectively. The diversity values and equability in evaluations were 2,888 nats.ind.-1 and 0,806 and 2,879 nats.ind.-1 and 0,786 respectively. In general, the data demonstrate that in the ciliary areas of the semi-arid the saplings bank is of largest importance for the regeneration of those atmospheres, because it allows the establishment of pioneering species and secondary initials providing an increment in the wealth of woody species in the community.
Aspectos da pedagogia no século XVII: um estudo comparativo entre João Amós Coménio e Alexandre de Gusmão
(Universidade Federal de São Carlos, 2008-05-15)
Pereira, Aline de Cássia Damasceno
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Bittar, Marisa
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https://lattes.cnpq.br/3187024660814929
Aprendizagem e inovação nas pequenas empresas : um estudo multicasos no arranjo produtivo local do setor do vestuário de Cianorte-PR
(Universidade Federal de São Carlos, 2008-05-16)
Oliveira, Márcia Freire de
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Torkomian, Ana Lúcia Vitale
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https://lattes.cnpq.br/5410927608982362
In company clusters, the proximity between the agents in a common socioeconomic context can facilitate relationships among companies and between those companies and other actors (clients, suppliers, universities, associations, etc.), creating spaces for the exchange of knowledge and information, and fomenting the learning process. This process is intertemporal and cumulative, helping to enable those companies to incorporate innovations. In view of this context, the main objective of this work was to ascertain whether the different forms of learning (learning by using, learning by doing, and learning by interacting) contribute to the introduction of innovations (commercial, organizational, institutional and technological) by the small companies inserted in production clusters. We hypothesize that learning by interaction is the form that most favors the introduction of innovations on the part of small companies inserted in production clusters. This research is qualitative; hence, it is an exploratory study. The focus of our analysis is the case of the garment sector s LPC (local production cluster) in Cianorte, state of Paraná, Brazil. To achieve the proposed objective, a multicase study was made of four garment producers established in this city. The data collection technique consisted of a bibliographic review, documental analyses, notes taken at meetings of the Cianorte LPC, and nonstructured interviews with employees of the four companies whose activities involved the adoption of innovations. Our findings do not confirm the initial hypothesis, indicating, instead, that learning by using contributes the most toward the introduction of innovations. Moreover, learning by interaction could represent a greater contribution if the local businessmen were to engage in joint actions aimed at achieving collective gains for the cluster.
Sistema baseado em redes neurais para composição musical assistida por computador
(Universidade Federal de São Carlos, 2008-05-16)
Corrêa, Débora Cristina
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Saito, José Hiroki
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https://lattes.cnpq.br/7065615446493390
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https://lattes.cnpq.br/7795579469691468
Several research studies have been realized in order to achieve a musical composition computational system that could, as much as possible, catch the human mind, skills, and creativity. More recently, artificial neural networks (ANNs), also have been deployed as auxiliary models for musical compositions. For musical computation, connectionist systems, as well as other systems that involve machine learning, are able to learn patterns and features available in the melodies of the training set and to generalize them to compose new melodies. Therefore, the use of neural networks in music learning and composition has attracted researchers and many approaches have been developed. The aim of this study is the proposal of a neural network based system for computer-aided musical composition. This system can be divided into four main processes: training, composition, evaluation and optimization. It is also proposed to complement the training and composition processes with a kind of inspiration, from Nature, using landscapes contours as additional information to the network. The neural networks used in the system are: BPTT (Back-Propagation Through Time) and LSTM (Long-Short Term Memory) networks. The results obtained are compared from both networks and it is observed that the LSTM network performs better. It is also proposed an approach that consists of optimizing the weight initialization process of the LSTM network in addition to an estimative of the ideal configuration of the hidden layer, that contributes to the obtained results.
Engenharia de interações e de reservatórios
(Universidade Federal de São Carlos, 2008-05-17)
Prado, Fabiano Oliveira
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Moussa, Miled Hassan Youssef
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https://lattes.cnpq.br/7828776012924524
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https://lattes.cnpq.br/3505195155149832
In this work we first present a protocol to build effective interactions between two cavity modes, considering a two-level atom under the action of classical fields. Bilinear Hamiltonians associated with parametric up- and down-conversion processes are derived, apart from nonlinear interactions associated with the degenerate parametric down-conversion process, resulting in the squeezing operation of a cavity mode. We also demonstrate how to construct nonlinear Hamiltonians related with a Kerr-type process for one or two cavity modes. In particular, we show how to implement, in the bimodal cavity, the Hamiltonian describing a two-specieis Bose-Einstein condensate in the two-mode approximation. Next, considering a two-level ion trapped in a cavity, under the action of classical amplification field, we show how to build an artificial reservoir for the electronic states of the ion. This reservoir is suited to protect nonstationary superpositions of the electronic levels, enabling us to measure the geometric phase acquired by these states under nonadiabatic evolutions of the system. Finally, we show how to construct squeezed reservoirs, either for a cavity mode or two-level atoms, by previously engineering an effective interaction between the atom(s) and the cavity mode which comprehends the simultaneous implementation of the Jaynes-Cummings and anti-Jaynes-Cummings Hamiltonians.
Estimulação diafragmática elétrica transcutânea (EDET) em mulheres obesas mórbidas submetidas à derivação gástrica em Y de Roux (DGYR) com anel de contenção, por laparotomia
(Universidade Federal de São Carlos, 2008-05-19)
Forti, Eli Maria Pazzianotto
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Costa, Dirceu
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https://lattes.cnpq.br/2664184377228086
The bariatric surgery has been considered an effective procedure for weight and co-morbidities reductions and consequently for the life quality improvement. However, in the same way as all surgeries, it can bring complications and alterations in the pulmonary function meanly in obeses. In this way, the objective of this study was the evaluation of the pulmonary function, the respiratory muscular strength and the thoracic mobility after the physiotherapy treatment with transcutaneous electric diaphragmatic stimulation (TEDS) in patients submitted to Roux-en-Y gastric bypass (RYGB) and the quality of their lives after the weight reduction. Forty-four morbid obese women with BMI > 40kg/m2 were studied. The Ethics Committee of Researches properly approved this study. The obese women were evaluated through spirometry, manovacuometry and thoracic abdominal cirtometry in the pre-operative period and fifteen and thirty days after the surgery ; they were randomly separated into two groups of twenty-two each. The Control Group (CG) was submitted to the conventional chest physiotherapy (CCP), while Experimental Group (EG) was submitted to the conventional chest physiotherapy associated with the TEDS (CCP+TEDS). The assessment of the life quality occurred between the sixth and the sixteenth month of the post-operative period by the BAROS questionnaire. To the statistics analysis was used GraphPad InStat for Windows, 3.05 version, the test of Kolmorogov Smirnov, Friedman and Mann-Whitney. It was considered significant p<0.05. To the data analysis of the BAROS questionnaire, descriptive statistics tests like average, standard deviation, absolute numeral values and percentage were used. The results showed that there were no statistically significant differences to the flows and pulmonary volume measurements and to the MIP (p>0.05). Related to the MEP, there was a progressive and significant reduction from the pre to the thirty day after the surgery for the CG, but not to the EG. It was observed that the alterations in the thorax abdominal mobility were not significant to the CG in any evaluation. However, with the EG, the differences were significant at the three moments of evaluations and to the three evaluated locals. Finally, the result of the quality of life questionnaire BAROS application showed that the bariatric surgery got satisfactory results to 2,27%, good to 9,10%, very good to 36,36% and excellent to 52,27% of the patients. Based on these results it is possible conclude that both CCP and (CCP) associated with TEDS were effective in the maintenance of pulmonary flows and volumes, of the capacity of muscle endurance, and the maintenance of the strenght muscles at the post-operative period of the RYDG. However, the CCP associated with the TEDS revealed to be much more effective not only to the maintenance of the expiratory muscles strenght as to guarantee a greater thorax abdominal mobility by increasing the muscle contraction. The loss of overweighting contributes to the life quality improvement in morbid obese women.
SLOT: uma ferramenta dinâmica para escalonamento global de aplicações em grades computacionais
(Universidade Federal de São Carlos, 2008-05-19)
Rios, Ricardo Araújo
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Guardia, Hélio Crestana
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https://lattes.cnpq.br/1780902767520967
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https://lattes.cnpq.br/0427387583450747
The constant improvement in performance that computers and interconnection networks present has favored the use of distributed computational resources, and given rise to Grid Computing. This new approach uses heterogeneous and geographically distributed resources to resolve problems with high computational costs. The execution of applications in this environment is generally achieved with scheduling mechanisms that manipulate the task set and its interdependences, mapping the tasks on to the resources. However, existing schedulers generate the schedule of each application individually, not evaluating the impact on the execution of previously scheduled applications. In this sense, this work presents a global scheduling tool for the tasks submitted to the Grid, and also presents a scheduling algorithm that allocates tasks between previously scheduled slots of time. The use of the proposed tool and algorithm permit a reduction in the amount of time processors remain idle and therefore a more efficient execution of the applications.
Gestão da qualidade e do desenvolvimento de produtos nos arranjos produtivos locais de confecções do Paraná
(Universidade Federal de São Carlos, 2008-05-19)
Monteiro, Antonio Roberto Giriboni
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Martins, Manoel Fernando
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https://lattes.cnpq.br/3921504261628850
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https://lattes.cnpq.br/8225119267165636
Due to the need to improve business competitiveness and create jobs, has seen in the last decade, the emergence of Brazil Local Clusters (APLs), following a trend seen in other countries, mainly in Italy. These arrangements are characterized by similar productive and high degree of interaction between companies. In Paraná were identified 22 APLs, seven of which are linked to the textile sector, this sector which is responsible for the second largest generation of jobs in the state. Considering the importance of APLs and the textile sector for the Paraná, this work was aimed at reviewing the major general practice of quality management and the development of products made by companies in local productive arrangements. He had specific goals as the characterization and comparison of APLs on quality management and development of products and identifies the actions of the government or local governance that can contribute to the development of APLs. To achieve the goals was conducted through a search of seven case studies APLs in the textile sector of Paraná. The main outcome was possible identify a heterogeneity in the treatment of quality management and the development of products in APLs of the state and in general where there is investment in quality management and the development of products there is a strengthening of the companies that are becoming, this so, less susceptible to external competition.
Metáforas e modelos da mente: das teorias do século XX à teoria modular de Jerry Fodor. O estatuto epistemológico das metáforas e modelos em filosofia da mente
(Universidade Federal de São Carlos, 2008-05-19)
Candiotto, Kleber Bez Birolo
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Teixeira, João de Fernandes
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https://lattes.cnpq.br/8864985279295912
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https://lattes.cnpq.br/3535420886883559
The aim of this research is to present a discussion and an analysis of the epistemological statute of the main theories regarding the philosophy of mind. In order to do that, we have developed some basic notions of the scientific investigation theory to determine the degree of assurance, certainty and scientificity that go with some of the descriptions, metaphors, models and theories concerning the philosophy of mind. After that, we organized an itinerary of the main models and metaphors in mind research, from the birth of 19th century Psychology to the Cognitive Sciences of the last three decades. We have identified the alternance criteria regarding the metaphors and models that have been used in research about the mind. Then, we reached what we have called a triple dominion of models, which has been used along the 20th and in the beginning of the 21st centuries: the representational and information processing model, deriving from the Cognitive Sciences; the Cognitive Neuroscience, which resumes philosophical issues such as mind and intentionality; and the biological model, specifically the one concerning Evolutionist Psychology. We have tried to demonstrate the epistemological and methodological bases and the competences of this new dominion of models, as well as their limits and reach. In this way, we come to the thesis itself: the proposition that Jerry A. Fodor s representational and modular notion of the mind is a perspective that converges on such triple dominion. We understand that Fodor s contributions are basic for a research program in the philosophy of mind, considering that the program aims at defining methodological strategies and it also reviews essential epistemological issues. Regarding the discussions about the mind, Fodor emphasizes that psychology requires philosophical support and that there should be a flow of theses from psychology to philosophy as well; in this way, reductionist theories and conceptual illusions would be avoided. Fodor s epistemological contribution is a reference regarding the explanation of mental states, avoiding the proliferation of terms and notions.
GRENJ: um framework obtido por um processo iterativo de reengenharia aplicando TDD
(Universidade Federal de São Carlos, 2008-05-21)
Durelli, Vinícius Humberto Serapilha
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Penteado, Rosângela Aparecida Dellosso
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https://lattes.cnpq.br/4061946080136286
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https://lattes.cnpq.br/8816910024419957
Software systems must satisfy the users requeriments and use current technologies. Thus, these systems are in constant evolution and several software maintenance tasks are carried out in order to adapt them to the user s requirements as well as to the current technologies. When there is a change in the technology used by these systems, an approach to their revitalization is reengineering, which is classified as a preventive maintenance. This research project presents the iterative process applied during the reengineering of the GREN framework, which is built based on the GRN pattern language. The GREN framework was originally implemented in Smalltalk, a very spread programming language, mainly within the academic community. In the proposed reengineering process the JavaTMlanguage and AspectJ, which is an aspect-oriented JavaTMextension, were used during the framework implementation resulting from the reengineering process. This new framework is called GRENJ. The proposed process can be used to reengineer systems developed with OO paradigm, in order to change its implementation language to another OO language. That process is iterative, incremental, and applies reverse engineering patterns, test-driven development and refactoring. The GRENJ framework has approximately twenty-eight thousand source code lines, of which approximately ten thousand are related to tests created during the development. The GRENJ framework documentation was generated using the javadoc tool. A hypothetical system that satisfies the basics requirements of a rental video store was instantiated using the GRENJ framework.
Avaliação do modelo de transtorno de estresse póstraumático (TEPT) e camundongos machos : efeitos do midazolam, sertralina e ausência de efeito da imipramina
(Universidade Federal de São Carlos, 2008-05-21)
Costa, Fernando de Souza Melo
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Souza, Azair Liane Matos do Canto de
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https://lattes.cnpq.br/2352004564367849
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https://lattes.cnpq.br/2982118089291826
The post-traumatic stress disorder (PTSD) affects a portion of subjects exposed to a traumatic event. This disorder leads to long-term alterations in the hypothalamus-pituitaryadrenal (HPA) axis, autonomic and cognitive function. The aim of our study was to evaluate whether the animal model of PTSD proposed for rats could be used in mice and, to evaluate the effect of benzodiazepine, tricycle antidepressant and selective serotonin reuptake inhibitor drugs in the PTSD model. For this we realized the following experiments: Experiment 1- The test consisted of exposure the male mice to inescapable electric footshock (0.3 mA) in the black side (BS) of the black-white box (BW). In the 7th, 14th and 21th day, mice were reexposed to the traumatic reminder on the white side (WS) or BS for 2 min, without footshock. In the 29th day, the animals were submitted to elevated plus-maze (EPM) for record the anxiety indexes [percentage of open arm entries (%OA) and percentage of open arm time (%OT) and as well as general locomotor activity, closed arm entries (CE)]. On day 34 the same animals were submitted to BW test for record the latency to escape (LE) from WS and time spent on WS of the BW box. Experiment 2 the same procedure of experiment 1 was performed, except that the animals were re-exposed at 7th, 14th e 21th days to reminder situation only in WS of BW box for 2 min, without footshock. On day 29th, the animals were exposed to EPM, 30 min after receiving treatment with midazolam. In 34th day the same animals after receiving treatment with midazolam were submitted to BW box test. Experiment 3, 4 and 5 - the same procedure was adopted from experiment 2, except that in 29th day, the animals were not submitted to EPM test and on 34th day 30 minutes after treatment with midazolam, imipramine and sertraline were submitted to BW box. Two-way ANOVA (stimulus x place remainder or treatment) followed by Duncan test showed that PTSD model increased anxiety in mice (P<0.05). The re-exposure in BS promoted anxiogenic-like effect extinction of the model. The midazolam treatment (1.0 and 2.0 mg/kg, i.p.) produced anxiolytic-like effect in maze-mice (P < 0.05) and the 0.5 mg/kg decreased latency to escape of WS (P < 0.05) of BW box and increased the exploratory activity, suggesting involvement of this GABA-benzodiazepine agonist on this PTSD modulation. The EPM test does not interfere in the evaluation of the BW test. It is important to note that no other behaviors were significantly altered by imipramine per se (P < 0.05). The sertraline (5.0 mg/kg), selective serotonin reuptake inhibitor, produced anxiolytic-like effect in the BW test (P < 0.05) and increase exploration activity. These results suggest that the employed PTSD model to study neurobiological disturbances associated with this disorder.
Quantificação de metacrilatos residuais e avaliação da liberação em saliva artificial a partir de resinas acrílicas para reembasamento imediato
(Universidade Federal de São Carlos, 2008-05-21)
Almeida, Fernando Gonçalves de
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Cass, Quezia Bezerra
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https://lattes.cnpq.br/9197210255594409
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https://lattes.cnpq.br/9535882123333210
This work reports the development of analytical methods, using High Performance of Liquid Chromatography (HPLC), to quantify unreacted monomers from dental reline autopolimerizing acrylic resins. The quantification of these unreacted methacrylates is directly related with theirs toxicity, once that these may not only be irritant to the mucosa, but may also cause allergic and inflammatory reactions. In addition to this, high concentrations of unreacted monomers may cause alterations in physical and mechanical properties. For this purpose, three experimental resins (RE1, RE2 and RE3) and a commercial resin, Tokuyama Rebase Fast II (TKY), were selected to be analyzed. The development of these experimental resins has been carried out in cooperation with Faculty of Dentistry, Araraquara (FOAr - Unesp) and the dental corporation VIPI Ltda (Pirassununga, SP). The relevance of development these new resins is related to the necessity to have a national confectioned resin, because all resins used for these treatments are imported and reducing the cost of treatment. For quantification of unreacted monomers was necessary to extract them from the resins, so the extraction procedure was carried out in an ice-bath using methanol as extraction solvent. This procedure was validated through extractions in replicates. The monomers quantified were acetoacetoxy ethyl methacrylate (AAEM) from TKY resin, ethylene glycol dimethacrylate (EDMA), buthanediol dimethacrylate (BDMA) and cyclo hexyl metharylate (CHMA) all from experimental resins. Higher concentrations were found for experimental resins which the unreacted monomers concentrations range were, approximately 120μg/mL to 500μg/mL, 150μg/mL to 500μg/mL and 100 to 300μg/mL for resins RE3, RE1 e RE2, respectively Only for TKY resin was carried out a procedure to evaluate the quantity of unreacted monomer leached out in vitro in artificial saliva. There were found concentration in the range from 5.00 to 64.0μg/mL, in view of that the higher concentrations were leached from resin in the first 24 hours and after one week of artificial saliva immersion it was not observed the leaching of AAEM monomer.
Vivendo a terceira idade em Vitória da Conquista : um estudo de caso acerca do impacto do programa da terceira idade da prefeitura municipal de Vitória da Conquista
(Universidade Federal de São Carlos, 2008-05-21)
Lima, Gabriel Azevedo Costa
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Mancuso, Maria Inês Rauter
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https://lattes.cnpq.br/9062169693386815
This research is about a case study assigned with old people from Vitória da Conquista, Bahia. These people participate in a program called Vivendo a Terceira Idade. This program belongs to Social Development Secretary from the Prefeitura Municipal de Vitória da Conquista and it was founded in 1997. Until the observation period which was occurred on the first semester in 2006, there were about four hundred old people participating in the program. The great part of these people came from popular districts and they were poor people. In living together groups, people participate by educative and leisure activities. These groups are situated in eight districts from the city and their meetings happen in their own districts or in the program space. The mainly objective by this research is understand what is the program influence in old people who participate. To make this work, the researcher chose inactive old people, who receive some periodic money from social security politics, like: retirement, pension, etc. This study was based in Pierre Bourdieu Sociology and our observation was about the familiar experiences from the old people in the program activities. Our discussion started from the facts raised by the participating observation, by the interviews, by the questionnaires and by the appreciation of the program documents. Besides, it was based in five analysis categories: gender, work, family, citizenship and resignifying. Through the adopted methodology, according to the theoretical referential, we tried to show how old people who participate in an Elderly program resignify their life references about identity and acquired social behavior. In general, this analysis suggest that old people pass to true reviewing life processes starting from the question about the values and the building of new priorities to drive their lives. This new reality redesigns the identities and provides changes in the center of the old people relationships with their families and with the society.
Influência do método de preparação e performance catalítica para os catalisadores de Pd-La2O3-Al2O3 aplicados na reforma autotérmica do metano
(Universidade Federal de São Carlos, 2008-05-21)
França, Alexandre Bôscaro
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Bueno, José Maria Corrêa
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https://lattes.cnpq.br/0157452280626031
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https://lattes.cnpq.br/4539473355526849
Pd catalysts supported on Al2O3 and La2O3-Al2O3 (12 wt.% La2O3) were prepared by wetness impregnation method with aqueous solution of of palladium nitrate (1 wt.% Pd). The supports were obtained by conventional method (PdAl-Conv. and PdLaAl-Conv.) and two different sol-gel methods with Al-sec-butoxide/HNO3/Ethanol (PdAl-SG-Et. and PdLaAl-SG-Et) and Al-sec-butoxide/CH3COOH/sec-butanol (PdAl- SG-2But. and PdLaAl-SG-2But.). The catalysts were characterized by X-ray diffraction (XRD), BET surface area of catalysts were calculated from nitrogen absorption isotherm (SBET), FTIR-CO adsorption spectroscopy and autothermal reforming of methane (ATRM). XRD of precursors shows diffraction lines of boehmit for -SGEt. sample and shows diffraction lines of aluminum acetate for -SG-2But sample. No peaks of Pd or PdO were reveled in all catalysts samples. SBET for PdAl-SG-Et, PdLaAl- SG-Et and PdAl-SG-2But.catalysts shows type IV adsorption isotherm and H1 hysteresis and for PdLaAl-SG-2But catalyst shows type III adsorption isotherm and H3 hysteresis. FTIR-CO show that the adding of lanthana on γ-Al2O3 suppress CO adsorption in bridge form over Pd. The CO adsorption form is insensitive to presence of lanthana in catalysts obtained by sol-gel method. The intensity of bands of CO in bridge (LF) and linear (HF) show a LF/HF ratio of 4.8 to 2.3 for PdAl-Conv. and PdLaAl- Conv catalysts, respectively. The Pd catalysts supported on Al2O3 show higher deactivation with time on stream on ATRM reaction, which is assigned mainly to coalescence of Pd particle. La-containing catalysts are quite stable and H2/CO ratio depends to the synthesis method.
Identificando dificuldades e benefícios do uso do PSP apoiado por ferramentas de 3ª. geração
(Universidade Federal de São Carlos, 2008-05-22)
Montebelo, Renan Polo
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Fabbri, Sandra Camargo Pinto Ferraz
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https://lattes.cnpq.br/2204086299921323
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https://lattes.cnpq.br/8516218359157043
Background: The Personal Software ProcessTM (PSP) is a methodology that can be used by software developers to improve the predictability, the productivity and the quality of their personal work. However, the great number of activities and metrics involved in the PSP makes its application very laborious and difficult. Several PSP supporting tools have been proposed in order to make its application more feasible, and such tools evolved as more experiments were conducted with the PSP. There are now three generations of PSP supporting tools, whereas third generation supporting tools are characterized by being able to collect and analyze Software Engineering metrics automatically and unobtrusively. Objective: This study s objective is to determine the difficulties and benefits of using third generation tools to support the PSP application. Method: The GQM paradigm was used to set up two Case Studies, one being in the academic environment with undergraduate students and another in a small software development company. Both case studies featured the PSP application supported by third generation tools. Results: Results show that third generation supporting tools have some advantages over previous generations tools, especially in the coding phase. However, third generation tools have limited PSP activities support and introduce new adoption problems. Conclusion: For a successful long-term PSP application, it is necessary that the supporting tools are completely adapted and integrated in the developers work environment, with both second and third generations tools characteristics.