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Ser caiçara em Ilhabela: as construções de identidade nas tensões entre o passado e o presente
(Universidade Federal de São Carlos, 2008-08-11)
Campos, Silmara Elena Alves de
;
Gonçalves Junior, Luiz
;
https://lattes.cnpq.br/7824385449132217
This survey was conducted with caiçaras of Ilhabela, a city-archipelago located in the northern coast of the State of São Paulo - Brazil. This social group is understood as part of social, economic, cultural and historical relations, which allows them to take ownership, learn and interpret the values and behaviors related to their own time and place. The question of this research study was: "What teaches the caiçara being caiçara in Ilhabela? The central objective was to understand the processes involved in educational development of the caiçara , taking into account its routine (ways to live, work, play , movie, teach and learn). The methodology used was phenomenological inspiration, and methodological procedures as daily field (16 descriptions) and interviews (13 descriptions). From the interviews transcription and subsequent analysis, 4 categories were established: "The caiçara world attacked"; "Being Caiçara ", "Resistance", "Recovering the caiçara culture" which allowed the completion of construction of combining results interviews with the field notes. In the considerations, it can be highlighted that despite the aggression and educational processes imposed to the caiçara world, these generate reactions contrary to them, such as those described by educational processes pertaining the fight for freedom, for a better world, in actions of solidarity, cooperation, resistance. We emphasize that at all times, it has been tried to impose to the caiçara people a pattern of language, social behavior, habits and customs, which will disrupt their way of life and that there, so there is a need for a political project that valorize the caiçara knowledge, the respect for diversity, ethical attitude, sustainable environmental responsibility and therefore humanitarian. Furthermore, we believe that the identity is not static, it is being-with-the-other-to-the-world.
Efeito do decanoato de nandrolona associado ao exercício de carga na expressão do fator de crescimento de endotélio vascular (VEGF) no músculo sóleo de ratos
(Universidade Federal de São Carlos, 2008-08-11)
Paschoal, Milena de Moura
;
Araújo, Heloísa Sobreiro Selistre de
;
https://lattes.cnpq.br/4065824911933203
;
https://lattes.cnpq.br/8452484361374652
Androgenic-anabolic steroids have been used both for performance improvement and aesthetic reasons. It is well know that high doses of AAS can raise serious adverse effects such as skeletal muscle injuries including increase in the rate of muscle strains/ruptures. The aim of this study was to investigate VEGF mRNA expression in the rat soleus muscle after jumping training associated with androgenic-anabolic steroids (AAS) administration. Wistar rats were grouped into: sedentary (S); trained without AAS (T); nandrolone decanoate (ND)-treated sedentary (AAS); and trained with AAS (AAST). The trained groups have carried out jumps in water at 32°C.: 4 series of 10 jumps each, with a 30-second interval among series, for 7 weeks, with 50- 80% overload of the animal corporal mass. The AAS (Decadurabolin® - 5mg/kg) was injected via subcutaneous in animal back twice a week. Real-time PCR analyses have shown that training significantly increased VEGF mRNA expression in comparison with the S, AAS groups. When training exercise was associated with nandrolone decanoate, the VEGF mRNA expression was inhibit compared with T group. The inhibited expression of VEGF by AAS administration could cause diminished angiogenesis in skeletal muscle. These results suggest that the AAS may be strongly prejudicial to muscle remodeling and performance.
Os agentes indígenas de saúde do Alto Xingu
(Universidade Federal de São Carlos, 2008-08-12)
Novo, Marina Pereira
;
Cardoso, Marina Denise
;
https://lattes.cnpq.br/6756345089486258
In the context of restructuring the indigenous health policies over the last 20 years in Brazil, and the consequent creation of the Special Sanitary Indigenous Districts since 1999, the Indigenous Health Agents appear as central elements of this new model for indigenous health attention, since they are understood as possible links or translators between the traditional systems and the official biomedicine. Considering this context, my intention was, through the presentation of ethnographic data about the formation process and the performance of the Indigenous Health Agents at the Upper Xingu, to question the role attributed to them, as well as the model of differentiated attention where this role was proposed. Exactly because they occupy a border position between different medicaltherapeutic systems, the agents performances are involved in several ambiguities and conflicts, which result from the imprecise definition of their functions, as well as from the effective existing conditions for their acting in the spaces attributed to them. I intend to show that the Indigenous Health Agents have their role redefined twice: by the non-indigenous professionals who think of them as transmitters of the biomedical knowledge to the attended populations as well as by the indigenous themselves, who see them as sources of goods and services from national society, in the general context of the political appropriation of this role and its acting spaces by the upper-xinguanos and local leaders themselves.
Cálculo e detalhamento prático de pilares para edificações de pequeno e médio porte
(Universidade Federal de São Carlos, 2008-08-12)
Miranda, Lucas Rodrigo
;
Carvalho, Roberto Chust
;
https://lattes.cnpq.br/3633394168236221
;
https://lattes.cnpq.br/1325545379168027
Even the small buildinging column may have a buckled. It s denoted the difficulty to design and detail this type of element. So this work intends make a description and application of a several simplified process of presizing and column s design. The stability building procedures of the parameters a e γz are analyzed are applied to this kind of structure. Also it s detailing how the wind forces are important in the internal forces and how to consider it in the column s design. The reinforced and the wind force are calculate by using a free program obtains at the internet. Several examples are made considering a characteristic building with one, two, tree and four pavements showing how to analize the stability, the presizing and column s design and showing too the final results. All this samples are solved and compared with a professional program and the it show that all results are too close. Finally a lot of commentary how to design the columns are made to aided engineers to make a good column s design for small and medium buildinging.
O erro corrigível e a ilusão inevitável na Crítica da Razão Pura de Kant
(Universidade Federal de São Carlos, 2008-08-13)
Dutra, Elias Sergio
;
Santos, Paulo Roberto Licht dos
;
https://lattes.cnpq.br/1681044854219924
;
https://lattes.cnpq.br/6964560647390588
The purpose of this work is to examine the problem of error and transcendental illusion in Kant s Critique of Pure Reason as two correlate, but sharply distinct aspects of his critique on dogmatic metaphysics. Following Kant s indications, we analyze his paradoxical doctrine that error is avoidable even if its positive source, transcendental illusion, is considered natural and inherent to human reason. Accordingly, we first analyze the status of error as a property of judgments in general Kant s thesis is that error can be explained in terms of a double influence that, if unnoticed, deviates the judgment from truth: imagination and sensibility. Under each of these influences, the human understanding helds merely subjective for objective principles of knowledge, thereby attaining error instead of true cognition. Secondly, applying this general analysis of error to one specific case, we focus our analyze on the issue of transcendental illusion involved in the transcendental idea of God In this particular case, we try to show how the legitimate demand of reason for a complete explanation (underlying the concept of God as an ens realissimum) allows room for a dialectic illusion, which holds that this concept of reason for a necessarily real and existing being. Finally, we try to point out the positive contribution to metaphysics which arises from Kant s distinction between judgmental error and transcendental illusion.
Análise de estruturas de rede neocognitron para aplicação no reconhecimento facial
(Universidade Federal de São Carlos, 2008-08-13)
Santana, Cristiane Oliveira de
;
Saito, José Hiroki
;
https://lattes.cnpq.br/7065615446493390
;
https://lattes.cnpq.br/5850109313490132
The present work consists in the use of the combination of neocognitron networks for the face recognition tasks integrating a system of face recognition, categorized as holistic method, by the fact of to approach all the face in the extration of the characteristics of the input image. The use of the face as biometric attribute in the recognition of individuous has grown mainly to its characteristic that dispense their cooperation for analysis. The great challenges in the area of face recognition are about the application in non-controlled environments in which the variation of illumination and pose can decrease the performance of the system. In order to work the challenges (variation of illumination and distortion in the patterns) it was used frontals images of CMU-PIE (University Carnegie Mellon - Pose, Illumination and Expression) database using the advantage of illumination and expression variations. The neural network model applied in the work is the neocognitron network that is capable to recognize patterns without its capacity of recognition been affected by deformations, changes in the size or position, of the input pattern. With the goal of to get the structure more adjusted of the neocognitron for the face recognition task, inside of a set of structures, it was analyzed some structures of neocognitron network with one output class and with different images resolutions. The best result corresponds to a recognition rate of 78% for a set with 30 classes with thirty and six patterns each one in the recognition phase. To improve the results it was applied combination of classifiers using: Decision Templates and the Modified Decision Templates method developed in this work. The performance of the classifiers was analyzed through the error estimation using the hold-out method and the Kappa coefficient. The final results pointed that the combination of classifiers applied to this model did not result in significant improvements due the inherent characteristics of the applied model.
Estudo de associação entre microssatélites localizados no cromossomo OAR3 e características de crescimento e resistência aos nematódeos gastrintestinais em ovinos
(Universidade Federal de São Carlos, 2008-08-15)
Gouveia, João José de Simoni
;
Regitano, Luciana Correia de Almeida
;
https://lattes.cnpq.br/6229827330214755
The sheep production has been growing surprinsingly in the last years in Brazil, but in despite of this, it can not be considered competitive yet, principally because the lack of structure and organization of the sector. Among the problems faced by the Brazilian sheep producers we could cite the gastrointestinal parasites and the relatively low productivity of the native breeds when compared with the exotic ones. The knowledge of the genetic factors controlling these traits can help in the improvement of then without impair the correlated traits. Through molecular biology and statistical technics is possible to identify genes/chromosomal regions associated with these traits and once the region is confirmed as really important in the control of the characteristic this information could be used in breeding programs through marker assisted selection. Many regions were identified as candidate for growth and nematode resistance traits in sheep and other ruminants, and among of them is the Q arm of the sheep chromosome OAR3. Because of this, the aim of this study was to investigate three microssatelite markers located in the Q arm of the OAR3 and its relationship with growth and nematode resistance traits in sheep from three genetic groups: Santa Inês X Santa Inês, Dorper X Santa Inês e Suffolk X Santa Inês. The association analysis revealed two alleles of the BL4 marker with significative effect in the Santa Inês x Santa Inês genetic group and one allele form the same marker with significative effect in the genetic group Dorper x Santa Inês on birth weight. It was also observed one allele from the BL4 marker associated with slaughter weight in the Santa Inês x Santa Inês genetic group. We did not observe any association between the markers studied and nematode resistance. Our results suggest that there are one or more genes in the studied region related with growth traits, but more studies are required to confirm the importance of this region in the control of these traits and to identificate the candidate genes.
As reformas educacionais de Benjamim Constant (1890-1891) e Francisco Campos (1930-1932): o projeto educacional das elites republicanas
(Universidade Federal de São Carlos, 2008-08-17)
Delaneze, Taís
;
Ferreira Junior, Amarilio
;
https://lattes.cnpq.br/0748545841167046
;
https://lattes.cnpq.br/8635772073038414
The study objects of this work are two educational reforms derived from the Public Federal Administration, namely the Reforms by Benjamim Constant (1890-1891) and Francisco Campos (1930-1932). Both are characterized by a series of decrees that legislated on several aspects of education and its degrees. The former was limited to regulating education in the Federal Capital (Rio de Janeiro), with the exception of high education, which was regulated nationwide. The later regulated the national education, thus representing a landmark in this sense. The Reform by Benjamim Constant was a product of the Proclamation of the Republic; and the one by Francisco Campos was the expanding of the conflagration of 1930. These two moments in the Brazilian political-economic context are the portrait of the same process: the bourgeois revolution in Brazil, which had not been finished in 1930, but, rather, had been provided with new impulses. The revolution that took place in Brazil did not follow the classical ways , which characterized, for example, the French Jacobinism. The process acclimated to Brazil was singular, but its analysis suggests similarities that are evidenced in the terms created by Lenin and Gramsci Prussian way and passive revolution, respectively. These two categories, which can be used as interpretative criteria for the Brazilian bourgeois revolution, develop the idea of conservative modernization, composed of modern and renewed elements that cause no revolutionary disruptions. While modernization is prompted by a segment of the conservative dominant class, revealing the reaction against the possibility of an effective transformation, it also absorbs part of the popular demand. In Brazil, the bourgeois spirit emerged from the agrarian aristocracy, which was responsible for the Modern State and contributed towards the capitalist development. In summary, the educational reforms resulting from this bourgeois context in Brazil, which were implemented by those conservative elites, reflected the educational thoughts by such elites. The primary education, essentially considered as the education for the people, was limited to Rio de Janeiro in the Reform by Benjamim Constant and not even mentioned in the Reform by Francisco Campos. Therefore, the education project of the republican elites included no expansion of the primary education, long retarding the establishment of both a public school, open to the subaltern classes, and a National Education System.
Indicadores de sustentabilidade para gestão de resíduos sólidos urbanos
(Universidade Federal de São Carlos, 2008-08-18)
Polaz, Carla Natacha Marcolino
;
Teixeira, Bernardo Arantes do Nascimento
;
https://lattes.cnpq.br/1166854416745527
;
https://lattes.cnpq.br/3722828980684272
One way to operationalize the concept of sustainability is through the use of indicators that are useful in planning, monitoring and evaluation steps of Municipal Solid Waste (MSW) policies. They can also help the public managers in setting priorities and goals, providing subsidies for technical decision making. The core objective of this research was to contribute to the development of sustainability indicators for public management of MSW in São Carlos/SP, from the perspective of five dimensions - environmental, economic, social, political and cultural. Based on a prior model proposed by Milanez (2002), the strategy adopted for the indicators adjustment to the São Carlos context was the analysis of the application model process in two consecutive years (2006/2007), followed by the identification of priority problems for the MSW management. For this, managers from two municipal divisions of the São Carlos prefecture, who work in different sectors related to MSW management, were consulted through semi-structured interviews. After the systematization of information obtained from the consultations, an initial proposal of indicators was drawn up. Through a workshop, the first set of indicators was then submitted to some specialists analysis. Both consultation processes (managers and specialists) resulted in the final set, composed of 15 indicators predominantly qualitative, distributed in the five dimensions considered. Of these, seven indicators were kept of the proposed Milanez set, three were adapted from literature and five were drafted from the identification of priorities for the MSW management in São Carlos. For each indicator were characterized the parameters of trend, expressed in three possible conditions: favorable, unfavorable or very unfavorable to sustainability. Since future applications were required to validate this proposal, the results obtained so far showed that the implementing process of a local indicators system should involve the participation of different actors in the selection, review and characterization steps in order to legitimize the effective use of this important management tool. However, the main difference resulting from the adoption of this type of indicator, will be a change in the perception of the general situation of MSW management, in which principles and dimensions of sustainability will be considered.
Efeitos do envelhecimento e do exercício físico sobre o sistema cardiovascular de indivíduos saudáveis
(Universidade Federal de São Carlos, 2008-08-18)
Melo, Ruth Caldeira de
;
Catai, Aparecida Maria
;
https://lattes.cnpq.br/9437079385922873
The ageing process is known to affect different tissues and systems. It is well-established that age-associated changes in cardiovascular structure and function are related to the risk of cardiovascular diseases. Because of the vast amount of cardiovascular modifications observed with ageing, the present study focused on three important topics: heart rate variability (HRV), blood pressure variability (BPV) and endothelial dysfunction. Furthermore, we also investigated the effects of physical activity (endurance and strength) on the autonomic control of heart rate (HR), which might be used as non-pharmacological therapy. Thirty five young subject between 18 and 30 years old (14 sedentary men, 5 sedentary women and 16 active men) and thirty eight middleaged/older subjects between 55 and 70 years old (16 sedentary men, 14 sedentary women and 8 active men) were studied. In addition, the subjects are distributed among 3 different studies. In the first one, the effects of the ageing process and active life-style on the autonomic control of HR were investigated in young and middleaged/older subjects. Electrocardiogram was recorded during 15 minutes of rest and 4 minutes of controlled breathing (5 to 6 cycles/min) in the supine position. HR and RR intervals were analyzed by time and frequency domain methods. The active groups presented lower HR and higher HRV (time domain) than the sedentary groups, whereas both middle-aged/older groups showed lower HRV (frequency domain). Additionally, interaction between ageing and life-style effects was observed for respiratory sinus arrhythmia (ASR) indexes (calculated during the controlled breathing test). The sedentary middle-aged/older group presented lower ASR magnitude than the other groups studied. The results suggest that ageing reduces HRV, however, regular physical activity improves vagal modulation on the heart and, consequently, attenuates the effects of ageing on the autonomic control of HR. In the second study, we aimed to investigate if strength training is able to improve cardiac autonomic control in healthy middle-aged/older men. HRV was evaluated before and after 12 weeks of isokinetic eccentric strength training (2days/week, 2-4 sets of 8-12 repetitions at 75-80% peak torque), involving knee flexion and extension. Strength training decreased the systolic blood pressure and increased the torque. However, an autonomic imbalance towards sympathetic modulation predominance was induced by an unknown mechanism. In the third study, we evaluated the effect of ageing on the BPV and endothelial function. We also sought for correlations between increased BPV and impaired endothelium dependent-dilation (EDD) in the middle-aged/older group. Intra-brachial artery BPV and conduit vessel EDD (brachial artery flow-mediated dilation, FMD) were determined in healthy young and middle-aged/older subjects. Moreover, endothelial function of resistance vessels was evaluated by venous occlusion plethysmoghaphy in the middle-aged/older group. The young group presented lower systemic oxidative stress, lower systolic BPV and higher FMD compared with the middle-aged/older group. After split this group according to the BPV, lower FMD was observed in the middleaged/older group with higher BPV. In addition, FMD was inversely correlated to BPV. The lower BPV group showed a great reduction (55%) in the forearm blood flow responses when NG-monometyl-L-arginine (nitric oxide inhibitor) was co-infused with acetylcholine (vs 14% in the higher BPV group). The results suggest that ageing process increases BPV and reduces endothelial function. Additionally, middle-aged/older subjects with higher BPV also have impaired EDD compared with their peers with lower BPV. General Conclusions: the results from the studies described above suggest that ageing process causes decrease of HRV, increase of BPV and decrease of endothelial function. Moreover, aerobic exercise has a cardioprotector effect, since it was able to attenuate the ageing effects on the cardiac vagal modulation. This same benefit, however, was not observed after 12 weeks of eccentric strength training. On the other hand, the strength training program performed by healthy older subjects modified the sympato-vagal balance toward the sympathetic modulation. Finally, systolic BPV oscillations seem to have a narrow relationship with vasodilation mediated by nitric oxide. Then, more studies are needed to clarify the cause-effect relation between those important variables.
São Carlos e o Movimento Constitucionalista de 1932: poder local e cooptação ideológica
(Universidade Federal de São Carlos, 2008-08-20)
Gomes, Pablo Ferreira dos Santos
;
Villa, Marco Antonio
This case study aims to analyze the participation of the city of São Carlos at the Constitutionalist Movement of 1932. It begins from a theoretical reference which allows to understand the main political groups that articulate the Constitutionalist Movement, the ideological speech that conducts them and the artifices used on the co-optation of the social classes. First of all, it is developed a situation analysis, and after that, the study focuses the local approach, where the participation of the city of São Carlos at the Constitutionalist Movement makes sense considering local politics since the First Republic, specially under the influence of the fast social and political changes occurred between the 20 s and 30 s. Therefore, the study of the local approach allows to understand the contradictions of the Constitutionalist Movement of 1932, with the defense of the democratic principles coexisting with the authoritarian methods for the co-optation of the public opinion and the restriction the dissidences.
Produção recombinante e caracterização de uma cisteíno protease (tipo catepsina B) de cana-de-açúcar
(Universidade Federal de São Carlos, 2008-08-20)
Duarte, Simone Michelan
;
Silva, Flávio Henrique da
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https://lattes.cnpq.br/1757309852446263
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https://lattes.cnpq.br/3194291973874319
Liofilização de frutas tropicais
(Universidade Federal de São Carlos, 2008-08-21)
Marques, Luanda Gimeno
;
Freire, José Teixeira
;
https://lattes.cnpq.br/2270677706718167
;
https://lattes.cnpq.br/7633174114536012
The national and international markets of processed fruits have continually grown due to the improved quality of the marketed product, the convenience of ready-to-serve products and because the availability of seasonal commodities has been extended by the processing which acts as a preservation technique. Besides aggregating commercial value to the fruit, drying reduces the wastes and the posharvest losses. Freezing-drying is the best drying method for heat sensitive materials and for obtaining a high quality dried product. Consequently, it has mainly been employed in the dehydration of materials with high commercial value such as tropical fruits. In order to contribute with the studies on lyophilization, the objective of this research was to analyse the freeze-drying of five tropical fruits, namely pineapple, acerola, guava, papaya and mango. For this, specific studies were carried out involving the determination of both the freezing and sublimation fronts, the analysis of the freeze-drying kinetics, the determination of structural properties (true and apparent densities and porosity) as a function of moisture content as well as of thermal properties (specific heat, thermal diffusivity and thermal conductivity) of the freeze-dried and fresh fruits. The influence of the process on the product quality was also evaluated through the determination of glass transition temperature, the vitamin C, total carotenoids, calcium and phosphorus contents and rehydration characteristics of the freeze-dried fruits. Total content of carotenoids was related to the values of chromatic parameters (L*, a*, and b*). Sorption isotherms of freeze-dried acerola using three freezing techniques (freezer, liquid nitrogen and nitrogen vapor) were determined. Empirical e semi-empirical equations were evaluated to describe to describe freeze-drying and rehydration kinetics. From indices that take into account the quantity of water absorbed and the losses of solutes it was possible to fully characterize the rehydration process of the freeze-dried fruits. Their water uptake capacity was affected not only by injuries during moisture removal but also by structural collapse induced by the rehydration process itself, which was explained using the glass transition concept. The shrinkage magnitude and the thermal behaviour of freeze-dried fruits were also affected by the glass transition phenomenon. Finally, freeze-drying and convective drying were compared in terms of product quality attributes, such as shrinkage, vitamin C retention and rehydration characteristics. Freeze-dried fruits were characterized by highly porous structures, high water uptake rates and elevated preservation of nutrients. The improved quality of the product is one of the main reasons that can contribute for increasing the demand for freeze-dried fruits in the food industry.
Desenvolvimento de metodologias para determinação de Cd e Pb em amostras de lodo de esgoto e sedimentos com o emprego da espectrometria de absorção atômica com forno tubular na chama e aerossol térmico
(Universidade Federal de São Carlos, 2008-08-21)
Souza, Silvéria Neves de Paula e
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Pereira Filho, Edenir Rodrigues
;
https://lattes.cnpq.br/3394181280355442
;
https://lattes.cnpq.br/7529571557934296
In this work, Thermospray Flame Furnace Atomic Absorption Spectrometry (TS-FF-AAS) and Flame Atomic Absorption Spectrometry (FAAS) were employed in order to propose methods for determination of total and bioavailability concentration of Cd and Pb in environmental samples. The sediments were collected in the basin of the Jundiaí river and the sewage sludge (industrial and home) in the Jundiaí sewage treatment station. The metals bioavailability contents were determined by extraction using 1.0 g of sample and 25.0 mL HCl 0.1 mol/L for 2 hours in horizontal stirrer 600 rpm. The total concentrations were determined using pre-digestion step for 12h followed by a microwave digestion of 0.1 g sample with 2.0 mL mixture concentrated HNO3 HCl (1:3 v/v) and 1.0 mL of H2O2 using heating program for 34 minutes. In determinations by TS-FF-AAS, 200 μL of sample was carried out into a nickel atomization tube with a flow rate of 0.5 mL/min. During Cd and Pb determinations in extracts HNO3 0.014 mol/L solution was used as carrier. In the case of the digested samples, EDTA 0.5% (m/v) and Triton X-100 0.1% (v/v) solution was used as carrier. The method accuracy was checked by Cd and Pb determination in in three certified samples: NIST 2782 and NIST 146R (industrials sludge) and NIST 8704 (Buffalo river sediment). The bioavailability and total concentrations range in sediments were 0.08-1.7 and 0.44- 2.47 mg/kg for Cd; 2.91- 13.6 and 8.9-24.7 mg/kg for Pb, respectively. Limits of detection (LOD) and quantification (LOQ) for TS-FF-AAS were 1.13 and 3.75 μg/L for Cd, 16.5 and 55.1 μg/L for Pb, respectively (n=3). In FAAS, limits of detection and quantification were 63.0 and 210 μg/L for Cd, 119 and 395 μg/L for Pb, respectively (n=3). The repeatability and reproducibility obtained were 1.0-8.0% and 7.0-24% for Cd, 2.4- 14% and 5.4-32% for Pb, presented as relative standard deviation (RSD, %).
Estudo fitoquímico de Euxylophora paraensis e avaliação das substâncias isoladas frente à enzima gliceraldeído-3-fosfato desidrogenase de Trypanosoma cruzi
(Universidade Federal de São Carlos, 2008-08-22)
Isidoro, Marsele Machado
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Silva, Maria Fátima das Graças Fernandes da
;
https://lattes.cnpq.br/0457632122660653
;
https://lattes.cnpq.br/1150094034053409
This work describe the phytochemical study of bark and leaves of the specie E. paraensis (Rutaceae). This dissertation aims at contributing with the chemistry of the Rutaceae family and evaluation of the antichagasic activity of substances isolated. The phythochemical study allowed to isolate fifteen secondary metabolites belonging to different classes: two alkaloids: N-methylflindersine and skimmianine; the mixture of three steroids: β-sitosterol, stigmasterol e campestanol; the limonoid limonin; six coumarins, which are: marmesin, 8-methoximarmesin, isooxypeucedanin, prangol, isopimpinellin and xanthotoxin; and three glycosides flavonoids: quercetin-3-β-O-rhamnopyranoside, myricetin-3-β- O-rhamnopyranoside and hesperidin, while there is still no reports on the isolation of flavonoids in this specie. The isolated compounds were evaluated as the enzyme inhibitory activity in Ggapdh (glyceraldehyde-3-phosphate-dehydrogenase) of T. cruzi. However, a strategy was used for virtual screening based on physical and chemical properties of substances isolated by the computer program Volsurf 3.0. The ability of the inhibitory compounds pre-classified was tested by isothermal titration calorimetry (ITC), which has characterized the mechanism of action of active substances on the enzyme GAPDH. Through the standardized test the following compounds were tested front of GAPDH: Limonin, quercetin-3-α-O-rhamnopyranoside and prangol showed that the inhibition constant ranging between 91.8 (± 18.08) and 384.8 (145 ± , 05) μM; hesperidin and marmesin that have not submitted activity against the enzyme.
Apoio de gerência de configuração de software ao ARA-GAwCRe
(Universidade Federal de São Carlos, 2008-08-22)
Borges, Simone de Sousa
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Penteado, Rosângela Aparecida Dellosso
;
https://lattes.cnpq.br/4061946080136286
;
https://lattes.cnpq.br/9013853025023946
Software systems suffer countless modifications during all its life cycle. Software Configuration Management (SCM) is concerned with organizing, controlling and managing the development and evolution of those systems. GAwCRe is a web application generator built based on Software Product Line for the rehabilitation clinics management domain. The generator instantiation is made through a Modelling Language that is based on the pattern language SiGCli. An ad hoc process has been proposed in order to apply the GAwCRe application generator within Arcabouço de Reengenharia Ágil (ARA). The ARA has the purpose of migrating small and medium procedural systems to the OO paradigm. This research presents an approach of SCM along with ARA to support the Processo de Reengenharia Ágil de Sistemas Legados Utilizando Geradores de Aplicações. The proposed approach uses a process, that is based on the standard IEEE 828-2005, to guide the planning of the SCM activities. Three systems were used: version control, changes control and build management. Other systems and tools are foreseen to provide the integration of the work spaces. The proposed approach supports the employ of the Processo Ágil de Reengenharia Utilizando Geradores de Aplicações associated with the ARA, other generators of applications built based in pattern languages also can be used to aid the design and implementation of the resulting system. Two legacy systems were partially reengineered applying the proposed approach.
Síntese, caracterização e estudo das propriedades fotofísicas de SiO2-GeO2 VAD encapsulada com Eu2O3
(Universidade Federal de São Carlos, 2008-08-22)
Oliveira, Larissa Helena de
;
Rosa, Ieda Lucia Viana
;
https://lattes.cnpq.br/8086262254116449
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https://lattes.cnpq.br/1461337173265474
Some materials can be encapsulated with metals, inorganic solids and biomolecules, in a nanometric scale, to form a nanocomposite which has specific properties that can be open to research and technology works. In the literature, they are represented as core@shell. When silica particles are coated with a luminescent material, as the Eu2O3, the final material will have different properties from the core and the shell material. The silica used as a core in this work is the silica-germania VAD, synthesized by the Vapor-phase Axial Deposition (VAD) technique, which has been given by the PhD. Carlos K. Suzuki from FEM-UNICAMP. The luminescent properties of the Eu3+ ion in the SiO2-GeO2@Eu2O3 material, has been studied to get some information about the environment around this ion during the heat treatment process. The emission spectra of the samples presented the main Eu3+ characteristics 5D0→7FJ ( J= 0,1,2,3, 4) bands. The degradation of the polymeric shell which involves the Eu3+ ions degradation occurs as the temperature increases, causing structural changes around this ion. With its degradation, the Eu3+ ion is incorporated to the silica-germania matrix. The interaction between this ion and the matrix is through Ge-O-Eu linkages, which suppress the Eu3+ luminescence. The same luminescence behavior is observed for the SiO2@Eu2O3 and SiO2@Eu2O3 spherical samples heat treat in the same temperatures. The lifetime curves for these materials when they are excited in its respective maximum of emission and excitation, present a mono-exponential feature and the values are higher than Eu2O3 pure. This material presented some novel optical properties, which makes it in a potential candidate to be used in a photonic area.
Os caminhos da docência na era digital: a utilização da sala de informática em escolas de São Carlos
(Universidade Federal de São Carlos, 2008-08-22)
Medeiros, Lilian Maria de
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Oliveira, Rosa Maria Moraes Anunciato de
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https://lattes.cnpq.br/3064136997342775
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https://lattes.cnpq.br/5485443089541989
In the present context, the continuous technological innovations and the emergence of new technologies allow the increase of the communication possibilities and the exchange of information and knowledge between people. In the educational field, we have contributions from recent studies with respect to the use of computers by teachers in the school context and its implications, as the studies by Valente, Barreto, Kenski, Beloni, Borba and Penteado, Fernandes, Monaco, and others. The present work is related to this field and seeks to answer the following question: What do the teachers think about the computer classrooms of the project School of the Future in São Carlos city for the students teaching and learning process? The goal of this work was to identify and to analyze the conceptions about the utilization of computers for the teaching-learning process in the school units where the project School of the Future is taking place. The main data source of this work was the answers to the questionnaire and interviews given by teachers who work in the school units where the project has been implemented. I analyzed the teachers perceptions on the possible contributions of the TICs to the work that has been carried out in the schools; on the students reactions to the use of computers in the classrooms; on the project School of the Future ; on the rules related to the use of the computer classrooms; and on the educational requirements for using the computers as a pedagogical tool. I used a questionnaire with open and close questions and semi-structured interviews in order to collect the data, which was analyzed later on in a qualitative way with the aim of establishing relations and identifying the perspectives of the research volunteers. For organization and systematization, some data is presented in graphs. To conclude, I realized that the teachers who took part in this research believe in the positive contribution of the use of computers in the school context, but they don t really use the available computers in the school due to lack of time, lack of skills or bureaucratic barriers. Also, many of them aren t aware of the school rules concerning the use of the computers, and in other cases, they believe that the computers classrooms should not be used by them. The data also revealed the necessity of some changes in the schools so that the teachers can use the available TICs, as well as more incentives by the education managers and the implementation of public policies for this practice.
Modelos de volatilidade estatística
(Universidade Federal de São Carlos, 2008-08-22)
Ishizawa, Danilo Kenji
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Moura, Maria Sílvia de Assis
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https://lattes.cnpq.br/9410151859448447
In the financial market usually notices are taken of the shares sequentially over the time in order to characterize them a time series. However, the major interest is to forecast the behavior of these shares. Motivated by this fact, a lot of models were created based on the past information considering constant averages and variance over time. Although, in financial series a feature often presented is called volatility, which can be noticed by the variance to vary in time. In order to catch this characteristic were developed the models of the family GARCH, that model the conditional variance through known information. These models were well used and have passed by many formulation modifications to be able to catch different effects, such as the effect leverage EGARCH. Thus, the goal is to estimate volatility patterns obeying the specifications of the family GARCH verifying which ones of them describe better the data inside and outside the sample.
Modelo I2P: recomendação de recursos baseando-se em preferências, interesses e popularidade
(Universidade Federal de São Carlos, 2008-08-22)
Gotardo, Reginaldo Aparecido
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Zorzo, Sérgio Donizetti
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https://lattes.cnpq.br/2523715806470871
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https://lattes.cnpq.br/2508538092205306
The development of technologies that assist in the teach-learning process is an rgued subject in some areas of knowledge. The great diffusion of Web-based Educational Systems (WbE-S) has been shown the popularization of distance learning and its support tools. The Tidia-Ae project, support by FAPESP, aim at the development of a WbE-S that can use the concept about high velocity internet. But, the WbE Systems don t have a personal treatment of user s necessities. So, the offers of personalization resources for systems aim at improving the teach-learning process using the treatment of real necessities of each user. The content recommendation, more specifically a recommendation system, is one of several techniques for that and it is a non-intrusive meaning of help user s in a system with a lot of information. This technique was used in Tidia-Ae environment to development of this thesis. This thesis presents the I2P model based on metrics of Interests, Preferences and Popularity which are acquired by the measuring of the relationship of users and system resources. These metrics provide a form to calculate the recommendation offers of resources. The calculation is done using Collaborative Filtering technique and the personalization is offered in collaborative form, considering the group learning.