Repository logo
Communities & Collections
Entire repository
About
English
العربية
বাংলা
Català
Čeština
Deutsch
Ελληνικά
Español
فارسی
Suomi
Français
Gàidhlig
ગુજરાતી
हिंदी
Magyar
Italiano
Қазақ
Latviešu
മലയാളം
मराठी
Nederlands
ଓଡିଆ
Polski
Português
Português do Brasil
Русский
Srpski (lat)
Српски
Svenska
తెలుగు
தமிழ்
Türkçe
Yкраї́нська
Tiếng Việt
繁体中文
Have you forgotten your password?
  1. Home
  2. Browse by Date

Browsing by Issue Date, starting with "2014-08-25"

Filter results by year or month
Now showing 1 - 20 of 16947
  • Results Per Page
  • Sort Options
  • Loading...
    Thumbnail Image
    Item type:Item,
    Insight : uma abordagem guiada pela informação para análise qualitativa com suporte de visualização e mineração de texto
    (Universidade Federal de São Carlos, 2014-08-25)
    Hernandes, Elis Cristina Montoro
    ;
    Fabbri, Sandra Camargo Pinto Ferraz
    ;
    https://lattes.cnpq.br/2204086299921323
    ;
    https://lattes.cnpq.br/0950017449730821
    Usually, experimental studies that are conducted to generate evidences on the different scientific fields produce many qualitative data to be analyzed by researchers. For instance, this is the case of defects lists generated from the software inspection activity, which defects consist of qualitative data that should be discussed and classified. This scenario was experienced during the Readers Project, where defects lists have token long time to be analyzed, sometimes hours or days, making the decisions about defects difficult. Moreover, feedback questionnaires deserved a careful analysis, since they carried relevant information about the experimental study. Aim: Driven by the described situation this research aimed to support the qualitative analysis conduction in an information-guided way, using visualization and text mining techniques to enable it. This approach allows software inspection defects described similarly be analyzed together, due to the use of these techniques, which may allow the homogeneity of the decisions about them. The same happens in the context of feedback questionnaires. Methodology: Based on the objective, the ways that visualization and text mining could contribute to become qualitative analysis more effective and efficient were investigated and designed. Considering it, the Insight tool was developed to enable the information-guided qualitative analysis. Experimental studies were conducted to validate and evaluate the approach on different contexts. Results: Four experimental studies were conducted: (i) a feasibility study conducted with text documents which gave evidences that the use of visualization and text mining met previous expectations and was feasible to be employed; (ii) a study in the context of software inspection which, although the quantitative data did not present statistical significance, the descriptive statistics and feedback questionnaires analysis gave evidences that visualization and text mining makes the qualitative analysis effective and efficient; (iii) a study in the context of questionnaires, which results were similar to the previous study; (iv) a case study in the context of qualitative analysis of long text documents which gave evidences about the utility and ease of use of the approach. Conclusion: Under the different contexts of evaluation, the Insight, an information-guided qualitative analysis approach that is based on visualization and text mining, gave evidences about the improvements on efficiency and effectiveness. Adding to its relevance in software engineering area, this research also contributes to other scientific fields, which often claim for technological support to conduct their research.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Desenvolvimento de filmes de carboximetilcelulose com nanopartículas de prata e avaliação de sua atividade antimicrobiana e toxicidade
    (Universidade Federal de São Carlos, 2014-08-25)
    Furlanetto, Maria Célia Siqueira
    ;
    Mattoso, Luiz Henrique Capparelli
    ;
    https://lattes.cnpq.br/5839043594908917
    ;
    https://lattes.cnpq.br/4909984450124700
    One alternative for new packagings is the use of renewable materials as raw materialin the development of films, with the challenge of maintaining the quality of the product. Polysaccharides are abundant and renewable origin, and its derivatives, such as carboxymethylcellulose, widely used in the food industry, have potential use as new materials in the form of films. However, there are challenges adequacies of mechanical properties and incorporation of new features (as antimicrobial) in carboxymethylcellulose films to make her suitable for packaging use. A promising system to modify the characteristics of these films is the incorporation of nanostructures. However, in Brazil there is no legislation to nanomaterials and the increased use of this technology, it is important to value the impact of these new materials from development to the final consumer, to better direct the search. In this context, the objective of this study was to develop carboxymethylcellulose films with PVA-silver nanoparticlesand evaluate their antimicrobial activity and toxicity. Silver nanoparticles were synthesized and incorporated in carboxymethylcellulose, via solution, obtaining films by casting. The following techniques to characterize films/solutions were used: spectrophotometry UV-Vis, Analysis of Particle Size, Zeta Potential, Water Vapor Permeability, Infrared Spectrophotometry, Thermal Analysis (Thermogravimetry and Differential Scanning Calorimetry), Mechanical Testing Tensile, Film Solubility in Water, Scanning Electron Microscopy (SEM / FEG) and Colorimetry. Generally, the addition of nanoparticles modified the characteristics of films, increasing mechanical properties at 66.7%. Evaluated the antimicrobial activity of the nanostructured system by Minimum Inhibitory Concentration (MIC) and inhibition zone, using Gram-positive bacteria (Enterococcus faecalis) and Gram-negative (Escherichia coli).MIC values showed the high effectiveness of the incorporation of the nanoparticles of CMC films (0,12^g mL-1), demonstrating the potential of this material for use in antimicrobial packages. In valuation of the toxicity of this nanostructured system, in vivo tests were performed in cultured cells (cyto and genotoxicity in Allium cepa), ingestion in Wistar rats and ecotoxicity in microcrustacean Daphnia similis. In meristematic cells of A. cepa, no result of cytotoxicity was verified in A. cepa. The analysis of chromosomal aberrations indicated predominance of abnormalities such as bridges chromosome in anaphase, verifying a clastogenic action of PVA-silver nanoparticles. Tests with rats have suggested the toxicity of nanostructured system, causing vacuolation in the liver and intestine crypt dilation, with accumulation of PVA-silver nanoparticles in ileum. Results of ecotoxicity have suggested a toxic potential of silver nanoparticles to aquatic invertebrates (CE5024 and 48 h equal to 0,0015 e 0,0012^g mL-1, respectively). The results of this study indicate that, even at low concentrations, PVA-silver nanoparticles can induce cellular damage in exposed organisms. Due to its increasing use, these data reinforce the importance of performing studies with silver nanoparticles as part of nanostructured systems.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Uma porta, várias saídas: análise do processo de reorientação da atenção à saúde mental de pessoas com transtorno mental em conflito com a lei através do Programa de Atenção Integral ao Louco Infrator (PAILI)
    (Universidade Federal de São Carlos, 2014-08-25)
    Costa, Lucio
    ;
    Leite, Kelen Christina
    ;
    https://lattes.cnpq.br/1659051697095067
    ;
    Garcia, Marcos Roberto Vieira
    ;
    http://lattes.cnpq.br/3911188481669270
    -
  • Loading...
    Thumbnail Image
    Item type:Item,
    A formação continuada de professores formadores do Cefapro de Barra do Garças (MT): um olhar sobre o processo formativo com enfoque na construção de saberes profissionais
    (Universidade Federal de São Carlos, 2014-08-26)
    Leão, Dinahmara Hild Ribeiro
    ;
    Nascimento, Fabrício do
    ;
    https://lattes.cnpq.br/3496410597486943
    ;
    https://lattes.cnpq.br/1205084360555950
    This study has as object of research the continuing education of the teacher trainers of the Training Centre of the State of Mato Grosso (CEFAPRO), aiming to investigate how the training process is composed in the Cefapro of Barra do Garças, with emphasis in the construction of professional knowledge. The study considered the continuing education process in progress and the teacher trainers were used as research subjects. The data were collected through interviews and theoretical arguments were used for their analysis to introduce the debate on the continuing education of teachers in the public policies for education, assuming that continued education includes the educational reforms in Brazil. We sought to understand the formation process in different dimensions and contexts, with theoretical foundation based on Nóvoa (1992, 1994, 1995, 1996, 2009), Marcelo García (1999, 2009), Imbernon (2002, 2009, 2010), Prada (1997, 2010), Tardif (2012), Freire (1979, 1982, 1996, 2001), among others. It is said that the continued formation of the Cefapro as a participatory proposal did not consolidate its training room for the construction of professional knowledge by the teacher trainers. The challenge for the continuing education of the Cefapro is to meet the educational policy, advancing beyond the limitations that it addresses to the practices committed to the transformation of the society
  • Loading...
    Thumbnail Image
    Item type:Item,
    Caracterização magnética de compósitos multiferróicos particulados Pb(Zr0,52Ti0,48)O4/CoFe2O4
    (Universidade Federal de São Carlos, 2014-08-26)
    Jimenez, Korllvary Rhanddy Charles Parra
    ;
    Oliveira, Adilson Jesus Aparecido de
    ;
    https://lattes.cnpq.br/4640148190073166
    ;
    https://lattes.cnpq.br/9545814170516633
    This work was studied the magnetic and electrical properties of particulate multiferroic composite Pb (Zr0,52Ti0,48) O4 / CoFe2O4 (PZT / CFO) (0-3 type) prepared by the polymeric method of Pechini and sintered by ultra-rapid method in microwave and conventional oven, with two molar concentration (80/20 and 50/50). These samples were characterized by ferroelectricity measurements as a function of applied electric field. And magnetization, magnetostriction and magnetoelectric effect as a function of magnetic applied. The main goal of our study was to analyze and characterization of the magnetic and magnetoeletric dependence of particulate composites PZT / CFO, where these samples exhibits two different grains size distribution of cobalt ferrite when compared of grain size average of PZT matrix, with two methods of sintering. We observed these samples present a dependence of the magnetic properties with the methods of sintering and the average grain size of ferrimagnetic phase. This effect was observed in the electric polarization of the ferroelectric PZT. In addition, differences were observed in the magnetic properties 5K and 300K, especially in the coercive field, for samples of cobalt ferrite and composite PZT / CFO 50/50, associated to differences of apparent densities.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Novas perspectivas para a comercialização de produtos agroecológicos: um estudo de caso em Hojarasca Carmen de Viboral, Colômbia
    (Universidade Federal de São Carlos, 2014-08-26)
    Souza, Gabriela Ferreira de
    ;
    Bertazzo, Cláudio José
    ;
    https://lattes.cnpq.br/1154385746854757
    ;
    https://lattes.cnpq.br/1398115392612782
    The systematization of an agroecological transition and the local-regional markets is extremely important to build knowledge on this area. This systematization enable people, who are involved on this work, to have more precise information, increasing the success in the whole process. The present study systematizes a marketing initiative of agroecological products in Carmen de Viboral, Colombian, Antioquia department, from its agroecological transition, the development, until the concretion and stability of its initiative. The methodological approach was based on a notorious local peasant´s narrative, named Carlos Osorio, it was analyzed the reasons that induced him to work with agroecology, the emergence of a marketing channel, and the meeting with consumers, was take into consideration. It was also observed his present structural and organizational aspects; distinguishing its consumers and the strategies that he used to establish the initiative. It makes use of a semi-structured interview, a questionnaire and Diagnostic Rural Participative. The theoretical framework used was Van der Ploeg (2008) and the Stiologia Zaoual theory (2006). This case study shows the reasons that induced a person to change radically not only his life, but the relation he has taking care of the soil, agriculture, and also their lives. The peasant was succeed of closing a cycle, from its production until finding an autonomous commercialization channel for his agroecological products using mechanisms of symmetric reciprocity; enhancing important values, that our society relativized or even forget about, such as, confidence, solidarity, ethics, love, honesty and long-term planning.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Termalização de qubits sujeitos à ação de reservatórios coletivos markovianos
    (Universidade Federal de São Carlos, 2014-08-26)
    Diniz, Emanuel Cardozo
    ;
    Villas-Bôas, Celso Jorge
    ;
    https://lattes.cnpq.br/5700887540085418
    ;
    https://lattes.cnpq.br/6386818101091884
    We are interested in understanding the process of Markovian thermalization in quantum systems when we have one or two qubits interacting with a quantum electromagnetic field mode, using the Rabi model, in situations where there is interaction with a reservoir modeling the environment surrounding the system. This analysis of the thermalization is based on the calculation of the eigenvalues of the Liouvillian of the Markovian master equation. We will focus mainly on situations where there is interaction with independent and collective reservoirs, for cases where the subsystems interact with reservoirs at T=0K and T >0K. We investigate situations where there is no thermalization of the system and how this may influence interesting physical properties, such as the statistical properties of the field in the ultra strong scheme using the theory of input-output and quantum correlations between qubits collectively interacting with Markovian reservoirs.
  • Loading...
    Thumbnail Image
    Item type:Item,
    A cultura punk e o underground: um estudo no cenário de duas cidades do interior paulista
    (Universidade Federal de São Carlos, 2014-08-26)
    Oliveira, Bruno Pereira de
    ;
    Dinis, Nilson Fernandes
    ;
    DINIS, N. F.
    ;
    https://lattes.cnpq.br/8750733554832790
    This essay is the result of the analysis of history fragments and Punk culture, as well as some artistic productions by the members of this movement, as zines and musics utilized by the Punks to defend their ideals and to establish its position before a hegemonic culture imposed on then. The productions analysed are the main sources of data for the fulfillment of this research, because the sources selected allow for an analysis considering the proximity between the Punk culture and the Underground scene from some similarities found during the research, as the influence of the Counterculture and the fight before the imposed standards. With the intention to elaborate a bibliographic review, considering the possible relations between the Punk movement and the Underground, being these elements present in most urban centers, this research is directed to two cities from São Paulo inland, Atibaia and Bragança Paulista, each one with its own culture and behavior. In this essay other movements besides the Punk are cited merely as comparative elements, because the Punk movement, its Underground component allies and all it's set of practices and actions, provide the minimally necessary data for the analysis of the proximity between the Punk culture and the Underground.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Interação entre osmorreceptores e mecanismos colinérgicos e angiotensinérgicos prosencefálicos no controle da ingestão de sódio
    (Universidade Federal de São Carlos, 2014-08-26)
    Roncari, Camila Ferreira
    ;
    Menani, José Vanderlei
    ;
    https://lattes.cnpq.br/0745253037526203
    Sodium intake is induced by facilitatory signals, such as angiotensin II (ANG II) and aldosterone. Hyperosmolarity and central cholinergic activation, classic antinatriorexigenic stimuli, also induce NaCl intake when the inhibitory mechanisms of the lateral parabrachial nucleus (LPBN) are deactivated. In the present study, we investigated the possible interaction between osmoreceptors and cholinergic and angiotensinergic mechanisms in the control of water and NaCl intake induced by different dipsogenic and/or natriorexigenic stimuli combined with the blockade of LPBN inhibitory mechanisms. Rats with stainless steel cannulas implanted in the lateral ventricle (LV) or subfornical organ (SFO) and bilaterally into the LPBN were used to study the effects of injections of atropine (muscarinic cholinergic antagonist), losartan or ZD 7155 (AT1 receptor antagonists) into the LV or SFO on water and 0.3 M NaCl intake induced by bilateral injections of moxonidine (α2- adrenoceptor/imidazoline agonist) into the LPBN combined with a) plasma hyperosmolarity induced by intragastric (ig) 2 M NaCl; b) injections of carbachol (cholinergic agonist) into the LV or SFO; c) subcutaneous injections of furosemide (FURO) and captopril (CAP); d) injection of ANG II into the LV. Additionally, we also investigated whether acute application of osmotic, angiotensinergic and cholinergic stimuli would activate cultured SFO dissociated cells and if the same cell would be activated by different stimuli. In rats treated with ig 2 M NaCl, injections of moxonidine (0.5 nmol/0.2 μl) into the LPBN increased water and 0.3 M NaCl intake. Injections into the LV or SFO of atropine (20 nmol/1.0 μl and 2 nmol/0.1 μl, respectively) or losartan (100 μg/1.0 μl and 1 μg/0.1 μl, respectively) abolished water and 0.3 M NaCl intake in rats treated with ig 2 M NaCl combined with moxonidine into the LPBN. Moxonidine injected into the LPBN also increased water and 0.3 M NaCl intake induced by FURO + CAP, injections of ANG II (50 ng/1.0 μl) and carbachol (4 nmol/1.0 μl) into the LV or carbachol (0.5 nmol/0.1 μl) into the SFO. The blockade of AT1 receptors with injections of losartan into the LV or ZD 7155 (1 μg/0.1 μl) into the SFO abolished water and 0.3 M NaCl intake in rats treated with carbachol into the LV or SFO combined with LPBN injections of moxonidine. However, atropine injected into the LV, despite reducing water intake, did not change 0.3 M NaCl intake in rats treated with FURO + CAP or injection of ANG II into the LV combined with injections of moxonidine into the LPBN. Injections of losartan into the LV reduced 0.06 M sucrose intake, but did not change food intake induced by 24 h of food deprivation. Finally, in vitro studies showed that osmotic, angiotensinergic and cholinergic stimuli activate SFO dissociated cells and that different stimuli can activate the same SFO cell. Therefore, the results of the present study suggest that different stimuli, such as hyperosmolarity and central cholinergic activation, facilitate NaCl intake through activation of central angiotensinergic mechanisms.
  • Loading...
    Thumbnail Image
    Item type:Item,
    FrAMC-i: um framework de apoio à produção de conteúdo multimídia complementar interativo
    (Universidade Federal de São Carlos, 2014-08-27)
    Rodrigues, Kamila Rios da Hora
    ;
    Penteado, Rosângela Aparecida Dellosso
    ;
    https://lattes.cnpq.br/4061946080136286
    ;
    https://lattes.cnpq.br/9035684997439778
    The television is the medium of information and entertainment most utilized by Brazilians. Despite its great reach, this vehicle, which should be an instrument to promote social inclusion, often causes the opposite effect. The manner some television programs are produced, in particular movies and series, combined with the lack of prior knowledge about certain subjects and contexts, trigger some viewers not to appreciate or enjoy enough of the programming, which may lead to a possible dissatisfaction in the audience. Cultural and educational matters may also accentuate the viewer's discontentment during a television session. New technologies such as the Interactive Digital TV (IDTV) allow the enrichment of television media with additional contents that may provide greater fruition of the narratives. This PhD project benefits from the flexibility and interactivity offered by the IDTV to propose a solution of accessibility based on the offer of additional specific contents, here denominated interactive Additional Multimedia Content (AMC-i). The AMC-i are extra information associated with the television media that may be offered to the main program considering different aspects, such as whether the offer: is synchronous or asynchronous, on demand or compulsory, with or without pausing the original program, by combining one or more media formats, among others. Through case studies, groups of spectators with distinct profiles, in different scenarios and interacting with varying kinds of media, were observed and had their interaction difficulties and experiences evaluated. This thesis proposes and presents the FrAMC-i, a framework consisting of a set of guidelines that support the production of AMC-i and emerged from the experience acquired during the observation of spectators in the studies. In addition to the guidelines, the FrAMC-i also provides tools for the enrichment of the media with AMC-i and a mobile application that enables the interaction with such contents by usage of a second screen. The framework was submitted to assessment by sixteen graduate students in Computer Science in the role of designers. These evaluators used the FrAMC-i artifacts to enrich media, given a provided fictional scenario. The results suggest a positive evaluation considering the utility, adherence to the proposed design solutions and usability of the artifacts supplied by the framework for the different stages of the production of the AMC-i.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Diretrizes, projetos, sala de aula: passos e descompassos da educação jurídica nos cursos de direito do estado de São Paulo
    (Universidade Federal de São Carlos, 2014-08-27)
    Mascaro, Arnaldo Braga
    ;
    Tagliavini, João Virgílio
    ;
    https://lattes.cnpq.br/6475591370235205
    This dissertation aims to demonstrate the steps and missteps in legal education in law courses in the state of São Paulo based on the analysis of Curriculum Guidelines and Political Pedagogical Projects (PPPs) and of their effectiveness in courses, through sampling. At this study s core is the concept that, at the level of discourse, the guidelines and PPPs are well developed and have content and methodology in accordance with the most recent findings in educational science. However, results have demonstrated the divergence between theory and practice. Taking into account that the state of São Paulo offers 220 of the nearly 1300 law degree programs available in Brazil, an analysis is performed of their necessity when less than half of college-aged Brazilians are enrolled in degree programs, a figure promised by the National Education Plan and the debate over inclusion with quality vs. exclusion. This analysis is done through a reading of the PPPs available at the Legal Education Commission of the Brazilian Lawyer s Order in São Paulo, which enabled an evaluation of the courses from 2010 to 2012, as well as interviews with members of the Commission. The present dissertation also draws from a thorough review of all law degree programs in the state of São Paulo, and their data was processed so as to be able to be accessed, altered and completed, thereby assisting researchers and the research group Education and Law in Contemporary Brazilian Society UFSCar, of which I am a member.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Descoberta dinâmica, sensível ao contexto, de serviços web
    (Universidade Federal de São Carlos, 2014-08-28)
    Silva, Victor Gomes da
    ;
    Prado, Antonio Francisco do
    ;
    https://lattes.cnpq.br/2668568143800755
    ;
    https://lattes.cnpq.br/1888388000918745
    Currently the Internet is one of the biggest media in the world, turning and accelerating forms of publishing and content consumption. At the same time, users have become more demanding for the content and the consumption of large amount of information that the Web provides. Since its inception, the Internet has gone through some phases, showing that the changes take place according to the requirements of users, such as the evolution of the Web to Web 2.0 which is marked by the interaction, collaboration and communication among users, who can publish and share their own content on the Internet. This reality has led to the need to build applications that support the large amount of information to users and different devices, arranged in multiple contexts of use, increasing the demand for software in Ubiquitous Computing, in which access to applications occurs anywhere, anytime and from different devices. The construction and maintenance of specific versions of applications for each context of use have become difficult due to the diversity of devices, users, access networks and other factors to be considered. Moreover, it is necessary for applications to be developed so that the compatibility of the contextual features of the environment in which they operate is maintained and does not impair the interaction of users. Motivated to overcome these challenges this work presents an architecture for Dynamic Discovery of Context-Sensitive Web Services that supports the creation of ubiquitous applications adaptive to different contexts. Applications driven by this architecture meet varying access networks in different contexts. The proposed architecture is based on the concepts of Service Oriented Architecture. The proposed architecture was evaluated with a case study and experimentation with users. The computational support that employs the proposed architecture has the advantage of discovering services at run time and can vary according to the context of the access network.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Controle preditivo não linear para sistemas de parâmetros distribuídos
    (Universidade Federal de São Carlos, 2014-08-28)
    Rodríguez, Diana Esperanza Sandoval
    ;
    Kwong, Wu Hong
    ;
    https://lattes.cnpq.br/0682354960749546
    In general, the chemical processes can be represented using mathematical models, in the case of lumped systems include ordinary differential equations, or, partial differential equations, when distributed parameter systems using methods is necessary in both cases numerical resolution in these models, with the purpose to simulate, analyze and control the process. The implementation of control systems in chemical processes, brings with it many advantages, among these, the improvement and stability in production rates, ensuring product quality and the possibility of a safe operation of the process. Thus, in the last 30 years, different control methodologies were developed, one of the most used techniques, the Model Predictive Control Based on. Its success is due to the fact that this type of control accepts constraints on input variables and process output, determining the future of this movement, while optimizing an objective function can lead to the output of the process until the desired set point. The objective of this project is to implement the Model Predictive Controller with Nonlinear (CPNL ) for a reactor pulp bleaching by the use of chlorine dioxide, whose mathematical model is comprised of partial differential equations, thus being a model parameter distributed. Implementation of the controller, the plant is discretized by the Finite Difference Method and the process model is solved with the technique of Orthogonal Collocation. The integration of the resulting ordinary differential equations systems is performed by the method of Runge-Kutta. The Predictive Controller was compared with a Controller Proportional-Integral (PI). Studies have shown that CPNL has better performance, with faster response and values of the Integral Absolute Error (IAE) and Integral Square Error (ISE) smaller than those calculated for the PI controller.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Estudos estruturais de duas 3 (Fenoximetil)-4-fenilbut-3-en-onas e docking no fator letal (LF) do bacillus anthracis (Antraz)
    (Universidade Federal de São Carlos, 2014-08-28)
    Nucci Junior, Paulo Roberto
    ;
    Moreira, Fernando Manuel Araújo
    ;
    https://lattes.cnpq.br/1809254923092721
    In this work the crystal structures of two 3 (phenoxymethyl)-4-phenylbut-3-en-ones were determined and the resulting 3D strutures were used as input for docking studies in the lethal factor (LF) of bacillus anthracis. The results were then compared with those of a known inhibitor.(3E)-3-(4-nitrophenoxymethyl)-4- phenylbut-3-en-2-one (1): the conformation about the C═C double bond [1.348 (2) Å] is E with the ketone group almost co-planar [C C C C torsion angle = 7.2 (2)°] but the phenyl group twisted away [C C C C =160.93 (17)°]. The terminal aromatic rings are almost perpendicular to each other [dihedral angle = 81.61 (9)°] giving themolecule an overall U-shape. The crystal packing feature benzene-C H O (aldehyde) contacts that lead to supramolecular helical chains along the b axis. These are connected by π π interactions between benzene and phenyl rings [inter-centroid distance = 3.6648 (14) Å] resulting in the formation of a supramolecular layer in the bc plane.(3E)-3-(2,4-dinitrophenoxymethyl)-4-phenylbut- 3-en-2-one (2): the conformation about the C=C double bond [1.345 (2) Å] is E, with the ketonemoiety almost coplanar [C C C C torsion angle = 9.5(2) °] along with the phenyl ring [C C C C = 5.9 (2) °]. The aromatic rings are almost perpendicular to each other [dihedral angle = 86.66 (7) °]. The 4-nitro moiety is approximately coplanar with the benzene ring to which it is attached [O N C C = 4.2 (2) °], whereas the one in the ortho position is twisted [O N C C = 138.28 (13) °]. The molecules associate via C H O interactions, involving both O atoms from the 2-nitro group, to form a helical supramolecular chain along [010]. Nitro nitro N O interactions [2.8461 (19) Å] connect the chains into layers that stack along[001]. The docking results, using as a target the lethal factor (LF) of bacillus anthracis, show that both Compound 1 and 2 located themselves in the same cavity where the known inhibitor is located, and making most of the interactions this last one does with the amino acid residues that are important for the enzyme activity, so that it can be postulated that they can be also inhibitors. Moreover, Compound 1adopts a pose closer to that of the inhibitor whereas Compound 2 is rotated so that an important interaction is missed, this may indicate that this last one can be a less effective inhibitor than Compound 1.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Consultas por similaridade e mineração de regras de associação: maximizando o conhecimento extraído de séries temporais
    (Universidade Federal de São Carlos, 2014-08-28)
    Andrade, Claudinei Garcia de
    ;
    Ribeiro, Marcela Xavier
    ;
    https://lattes.cnpq.br/0300141044144026
    ;
    https://lattes.cnpq.br/5690286318736653
    A time series analysis presents challenges. There is a difficulty to manipulate the data by requiring a large computational cost, or even, by the difficulty of finding subsequences that have the same characteristics. However, this analysis is important for understanding the evolution of various phenomena such as climate change, changes in financial markets among others. This project proposed the development of a method for performing similarity queries in time series that have better performance and accuracy than the state-of-art and a method of mining association rules in series using similarity. The experiments performed have applied the proposed methods in real data sets, bringing relevant knowledge, indicating that both methods are suitable for analysis by similarity of one-dimensional and multidimensional time series.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Trailer do filme Psicose, para além do marketing cinematográfico
    (Universidade Federal de São Carlos, 2014-08-29)
    Constantino, Maria Julia évora
    ;
    Monzani, Josette Maria Alves de Souza
    ;
    https://lattes.cnpq.br/0505156751073470
    ;
    https://lattes.cnpq.br/8654431191020019
    The objective of this dissertation is to study the narrative of the trailer of one of the most influential films in cinema history: Alfred Hitchcock´s Psycho (1960). The trailer will, therefore, be analyzed not only as a tool of movie marketing, but mostly as a 'shortmovie' which has a kind of parallel narrative and assist in the feature film, with a beginning, middle and end, trying to understand how that is constituted and how it still speaks to the disclosure´s posters and the opening credits of the film. Both 'core' sequence storyboard´s (trailer and movie) will also be used in this reading that seeks to comprehend the process of signification in the orbit of Psycho.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Bergson e o eu dividido
    (Universidade Federal de São Carlos, 2014-08-29)
    Ribeiro, Eduardo Soares
    ;
    Marques, Silene Torres
    ;
    https://lattes.cnpq.br/4822141288006918
    ;
    https://lattes.cnpq.br/1452378874288074
    This work is aimed at investigating the inner life in Bergson s first book, Time and Free Will An essay on the immediate data of consciousness (1889). We try to analyze especially the notions of duration and space in light of what we call the divided self , i.e., the division established by Bergson between the superficial self related to space, social life and language and the deap-seated self which concerns the pure duration of consciousness, the continuous multiplicity of interpenetration of psychological states and creating and unpredictability that constitutes each free act. At the end, and already in possession of the conclusions on the Essay, we will discuss the bergsonian intuitive method and its relationship with the divided self.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Análise de risco do aproveitamento da água de chuva para uso não potável em edificações
    (Universidade Federal de São Carlos, 2014-08-29)
    Bassanesi, Karine
    ;
    Barreto, Douglas
    ;
    https://lattes.cnpq.br/7369326190168139
    ;
    https://lattes.cnpq.br/4154058724586056
    This master degree contains a literature review on the conservation of water, rainwater utilization, quality and water treatment, legislation and risk analysis. Was verified that rainwater utilization systems vary widely in type and would be important to be able to correlate the precipitated water, uses and models for each situation. And for this work was used the risk analysis focusing the preliminary hazard analysis. A bibliographic review carried out presented some guides and legislation that could complete quality control parameters for non-potable rainwater utilization, and determine the time to review these parameters to control the operation of the system. The study's preliminary analysis was used to study the greatest dangers in the use of rain-related water quality system, critical control points, the user risks, control measures and mitigation measures. For the case study was addressed the same preliminary hazard analysis for knowledge about the contamination of rainwater in relation to the control parameters and on their own knowledge of project development for rainwater utilization. Through the two analyzes a proposal of guidelines was performed for implantation of rainwater utilization system for the case study and there is a possibility of a real fitness for safe use.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Teores de nutrientes minerais e metais pesados em açúcar mascavo produzido por diferentes sistemas orgânicos e convencionais
    (Universidade Federal de São Carlos, 2014-08-29)
    Luchini, Paulo Dirceu
    ;
    Borges, Maria Teresa Mendes Ribeiro
    ;
    https://lattes.cnpq.br/1800048119205212
    ;
    https://lattes.cnpq.br/1639064301786387
    The levels of Cu, Zn, Mn, Fe, Pb and Cd were determined in brown sugar from sugar cane produced by different crop systems in the organic and conventional systems. Pb e Cd were determined by atomic absorption spectrometry with electro thermal atomization in graphite furnace (GFAA), and the mineral metals Cu, Zn, Mn and Fe were determined by flame atomic absorption spectrometry (FAAS). Cu, Zn, Mn and Fe were detected but in levels below the limits recommended by the World Health Organization. The brown sugar from the conventional system without limestone but with chemical fertilizer showed the highest concentration of Cu, Zn, Mn and Fe, and that from the organic system with liming and organic compost showed the lowest concentrations. The levels of Pb found in samples from: conventional system with organic amendment and chemical fertilizer, and with liming and chemical fertilizer, and from organic system with liming and organic compost were higher than the tolerable limit for the Brazilian National Health Surveillance Agency for sugar. Cd was never detected. The results indicate the need of constant monitoring studies of the brown sugar produced in organic systems to assure its food safety.
  • Loading...
    Thumbnail Image
    Item type:Item,
    Instituições participativas: audiências públicas para revisão do plano diretor no município de Araraquara
    (Universidade Federal de São Carlos, 2014-08-29)
    Lopes, Maira Gonçalves
    ;
    Lahuerta, Milton
    ;
    https://lattes.cnpq.br/9326718732298388
    ;
    https://lattes.cnpq.br/8027586789638304
    On the traversed course through the literature about institutional participation, it is possible to point distinct moments to deal with. In this dissertation was recovered the discussion approached by Carlos Estevam Martins, that in the end of the eighties and begin of nineties, bring forward the participation theme into the theory of the State and highlighted the relationship of participation and representation in this context. Following, we brought to the debate inspired research by the Habermasian theory, that pointed to an enthusiasm with the new forms of institutional participation. Subsenquently, research showed that was a large disparity between empiric bases and normative expectations in the literature until then. The last and current moment, focuses its efforts to the effective question of participation. During this period, many participation institutions (PIs) was analyzed and evaluated, however, the research about Public Hearings was rare. Based in the literature balance, this dissertation proposed to analyze Public Hearings, in the municipality of Araraquara-SP( Brazil), that was made throughout the revision process of the Master Plan of this city in 2013. The research point that the hearings, because of yours advisory character, worked as debate environments, but not as a political instrument of propositions and decisions. In addition, this Public Hearings operate as a subordinate participation instrument of government authority, because is that one who is able to incorporate or reject submitted suggestions by the population in this environment.
  • «
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 9
  • 10
  • ...
  • 848
  • »
Siga as redes sociais do SIBi
Contato

Repositório Institucional da UFSCar (RI UFSCar)

Av. Biblioteca Comunitária, Campus São Carlos

Rod. Washington Luís, km 235 - SP-310

São Carlos, SP, 13565-905 (16) 3351-8477

Email: repositorio@ufscar.br

Acessos ao repositorio.ufscar.br
Consultar estatísticas de acesso

DSpace software copyright © 2002-2026 LYRASIS

  • Accessibility settings
  • Privacy policy
  • End User Agreement