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Item type:Item, Localização de centros de auxílio e distribuição de suprimentos em operações de respostas a desastres(Universidade Federal de São Carlos, 2015-09-15) ;Moreno, Alfredo Daniel Arteaga ;Alem Junior, Douglas José ;https://lattes.cnpq.br/074444826415006https://lattes.cnpq.br/8809415112629602The recent natural disasters around the world have shown the difficulties of the various organi- zations in effectively manage post-disaster operations. These difficulties reflect the complexity of the activities involved in those situations. Among the many decisions that must be made quickly in disaster situations, the location of relief centers and the distribution of supplies are essential to the survival of the affected community. On the other hand, operation as fleet sizing are also relevant since it is a scarce resource the available vehicles to perform the distribution of commodities. Although many studies in the literature have developed mathematical models to assist such decisions, few authors have integrated these decisions to get solutions that are more efficient. In the present work this integration is studied, they are developed mixed integer stochastic programming models to support location decisions, distribution and fleet sizing in a multi-period, multi-product and multi-modal context, and considering some uncertainties that are common in disasters, such as number of victims, availability of supplies, proportion of available inventory and arc availability. Also, it is considers the transportation time and social costs in the objective function. Decomposition heuristics were developed to solve large instances of the problem. Models and heuristics were analyzed based on the megadisaster in the Mountain Region of Rio de Janeiro in Brazil in 2011. The results indicate that the developed mathematical models provide efficient solutions from a practical point of view and that the implemented heuristics are efficient to solve practical instances of the modelsItem type:Item, Entre os documentos e as retomadas : movimentos da luta pelo território em Brejo dos Crioulos (MG)(Universidade Federal de São Carlos, 2015-09-15) ;Costa, Pedro Henrique Mourthé de Araújo ;Vianna, Anna Catarina Morawska ;https://lattes.cnpq.br/2245801371286766https://lattes.cnpq.br/7997930341504935It has been seventeen years of struggle since the opening of the legal procedures for the recognition of Brejo dos Crioulos - a community located in the Outback North Miner, on the border of three cities - São João da Ponte, Verdelâ ndia and Varzelâ ndia -, as a “quilombo remnant territory”. Victims of a violent territorial expropriation process since the mid-1930s, the quilombolas started retaking their territory in 1998, with confrontations inside and outside the quilombo with the aim of pushing forward the process of land titling. Due to the slowness of the State in dispossessing the farmers who have ocupied the region ilegally, the quilombolas haved used two strategies in their confrontations: the retomadas [land retaking] and the mobilization of a partners network and of documents - legal proceedings, reports, anthropological report, decrees, correspondence, notes, projects, inquiries and police inquiries - in different institutions and in various courts, featuring a bureaucratic universe that is actuated at various moment. This landscape of conflict is composed by an interweaving of various political forces. This dissertation deals with the various movements that make up the struggle for the territory in Brejo dos Crioulos, which was only recognized as a “quilombo remnant” by the Palmares Cultural Foundation (FCP) in 2004, by describing ethnographic encounters between the quilombolas, anthropology and State in the course of the titling process.Item type:Item, Modelagem de dados de sistemas reparáveis com fragilidade(Universidade Federal de São Carlos, 2015-09-15) ;Feitosa, Cirdêmia Costa ;Tomazella, Vera Lucia Damasceno ;https://lattes.cnpq.br/8870556978317000https://lattes.cnpq.br/9062816668207162The usual models in repairable systems are minimal, perfect and imperfect repair, and, in the literature, the minimum repair model is the most explored. In repairable systems it is common that the same type of components are studied and in these cases is relevant to verify the heterogeneity between them. According to Vaupel et al. (1979), the standard methods for analysis of repairable systems data ignore the heterogeneity not observed and in some cases this should be considered. Such variability can be estimated from frailty models, characterized by using a random e ect. It is proposed that the minimum repair model with frailty in order to estimate the heterogeneity not observed between systems. For this model it was conducted a simulation study in order to analyze the frequentist properties of the estimation process. The application of a real data set showed the applicability of the proposed model, in which the estimation of the parameters were determined from maximum likelihood and Bayesian approaches.Item type:Item, Uma abordagem para construção de sistemas fuzzy baseados em regras integrando conhecimento de especialistas e extraído de dados(Universidade Federal de São Carlos, 2015-09-17) ;Lima, Helano Póvoas de ;Camargo, Heloisa de Arruda ;https://lattes.cnpq.br/0487231065057783https://lattes.cnpq.br/4850820391832869Historically, since Mamdani proposed his model of fuzzy rule-based system, a lot has changed in the construction process of this type of models. For a long time, the research efforts were directed towards the automatic construction of accurate models starting from data, making fuzzy systems almost mere function approximators. Realizing that this approach escaped from the original concept of fuzzy theory, more recently, researchers attention focused on the automatic construction of more interpretable models. However, such models, although interpretable, might not make sense to the expert. This work proposes an interactive methodology for constructing fuzzy rule-based systems, which aims to integrate the knowledge extracted from experts and induced from data, hoping to contribute to the solution of the mentioned problem. The approach consists of six steps. Feature selection, fuzzy partitions definition, expert rule base definition, genetic learning of rule base, rule bases conciliation and genetic optimization of fuzzy partitions. The optimization and learning steps used multiobjective genetic algorithms with custom operators for each task. A software tool was implemented to support the application of the approach, offering graphical and command line interfaces and a software library. The efficiency of the approach was evaluated by a case study where a fuzzy rule-based system was constructed in order to offer support to the evaluation of reproductive fitness of Nelore bulls. The result was compared to fully manual and fully automatic construction methodologies, the accuracy was also compared to classical algorithms for classification.Item type:Item, Participação dos receptores purinérgicos P2 no núcleo do trato solitário sobre as respostas cardiorrespiratórias induzidas por hipóxia(Universidade Federal de São Carlos, 2015-09-18) ;Marques, Naira ;Paula, Patrícia Maria de ;https://lattes.cnpq.br/0201361251312074https://lattes.cnpq.br/9275522584355383Cardiorespiratory responses to hypoxia are controlled by brainstem areas including the nucleus of the solitary tract (NTS). In the present study, we investigated the effects of suramin (a non-selective purinergic receptor antagonist), MRS 2179 (a selective P2Y1 purinergic receptor antagonist), PPADS (P2 purinergic receptor antagonist), alpha,beta-meATP (a selective P2X purinergic receptor agonist) and MRS 2365 (a selective P2Y1 purinergic receptor agonist) injected into the NTS on cardiorespiratory responses to hypoxia in conscious rats. Male Holtzman rats (290-310g, n=5-9/group) with stainless steel cannulas implanted into the NTS were used. We recording mean arterial pressure (MAP) and heart rate (HR) in conscious rats. Respiratory frequency (fR), tidal volume (Vt) and ventilation (VE) were recorded by whole-body plethysmography. VE, fR, Vt, MAP and HR were recorded in hypoxia (7% O2 for 35 min). Rats received bilateral injections of suramin (2 nmol/100 nL), MRS 2179 (1 nmol/100 nL), PPADS (2 nmol/100 nL), alpha,beta-meATP (2 nmol/100 nL), MRS 236 (1nmol/100 nL) or saline into the NTS 10 min before starting the hypoxia. Hypoxia reduced MAP (97 ± 3 mmHg, vs. normoxia: 119 ± 4 mmHg, p < 0.05) and increased HR (448 ± 17 bpm, vs. normoxia: 392 ± 18 bpm, p < 0.05) and VE (917 ±46 mL.min-1.Kg-1, vs. normoxia: 492 ±26 mL.min-1.Kg-1, p < 0.05). Bilateral injections of suramin into the NTS reduced Vt during hypoxia (7.1 ± 0.4 mL.Kg-1, vs. saline: 8.6 ± 0.5 mL.Kg-1, p = 0.046) resulting in a decrease in the hypoxia-induced hyperventilation (843 ± 66 mL.min-1.Kg-1, vs. saline: 1073 ± 98 mL.min-1.Kg-1, p = 0.05) without changing tachypnea induced by hypoxia (117 ± 3 breaths.min-1, vs. saline: 123 ± 6 breaths.min-1, p > 0.05), MAP (88 ± 5 mmHg, vs. saline: 94 ± 6 mmHg, p > 0.05) and HR (411 ± 19 bpm, vs. saline: 444 ± 20 bpm, p > 0.05). Furthermore, bilateral injections of MRS 2179 into the NTS reduced Vt during hypoxia (6.1 ± 0.5 mL.Kg-1, vs. saline: 7.4 ± 0.4 mL.Kg-1, p = 0.031) and hypoxia-induced hyperventilation (763 ± 77 mL.min-1.Kg-1, vs. saline: 917 ± mL.min-1.Kg-1, p = 0.043), without changing tachypnea (125 ± 10 breaths.min-1, vs. saline: 124 ± 4 breaths.min-1, p > 0.05), MAP (93 ± 1 mmHg, vs. saline: 97± 3 mmHg, p > 0.05) or HR (420 ± 23 bpm, vs. saline 448 ± 17 bpm, p > 0.05) during hypoxia. Bilateral injections of PPADS, alpha,beta meATP and MRS 2365 into the NTS did not change VE, MAP and HR on hypoxia condition. The present data show that P2 purinergic receptors, especially P2Y1, in the NTS are involved in the respiratory responses induced by hypoxia.Item type:Item, Azedinha (Rumex acetosa L.) : caracterização morfológica, requerimento nutricional e qualidade sensorial(Universidade Federal de São Carlos, 2015-09-18) ;Lima, Maria Angélica Suedan Souza ;Soares, Marcio Roberto ;Sebastiani, Renata ;https://lattes.cnpq.br/6337462438517339Fontanetti, AnastáciaAzedinha (Rumex acetosa L.) has pleased the consumer for its sour taste. Considered an unconventional vegetable, their redemption becomes important to allow notable gains from the nutritional, social, cultural, economic and environmental point of view. The objective was to characterize morphologically copies of azedinha obtained from seeds, determine their sensory characteristics and acceptance, as well as analyze some physicochemical parameters, and determine the absorptions of macro and micronutrients and biometric parameters during 60 days after transplanting (DAT). The experiment was conducted at the Centro de Ciências Agrárias, belonging to the Universidade Federal São Carlos - UFSCar in the city of Araras - SP. Biometric parameters were evaluated (length of the leaf, relative leaf area, fresh and dry weight of shoots) and the macro and micronutrients absorption march from plants collected at 15, 20, 25, 30, 35, 40, 50 and 60 DAT. They evaluated the length, width and length / width ratio of leaf blade; petiole length and width close to the blade; diameter of the stump; the shoot length; length of ochreas; shape of the leaf blade; kind of apex; base form; type of veining and type of margin of the leaf blade; type of ochreas; characterization of the stem; length and diameter (neck) of the root. It also determined the levels of ascorbic acid, phenolic compounds and chlorophyll parameter. For sensory analysis was used the Quantitative Descriptive Analysis (QDA). Sensory analysis of acceptance was conducted with 52 judges, in relation to vii appearance, aroma, flavor, texture and overall impression, as well as purchase intent. The biometric parameters increased over time after transplantation and most markedly after the recommended times for harvest (20 and 35 DAT). The maximum levels of macro and micronutrients accumulated in the shoot, in descending order were as follows: K > N > Mg > P and Fe > Mn > Zn > Cu. The morphological descriptors with greater discriminatory power for azedinha were the types of margin and venation of the leaf blade, the characterization of the stem, the presence of ochrea and shape of the leaf blade, ranging from sagittate the hastate. It also infers that the best harvest time is between 20 and 35 DAT. The average content of ascorbic acid was 10,25 mg 100g-1 sample, total phenolic 291,46 mg of gallic acid 100 g-1 dry weight and chlorophyll parameter was 36,6 SPAD units. As for the quantitative descriptive analysis, the leaves of azedinha framed up closer to dark green; most have arrow or spear shape; smooth; with sharp aroma of grape skin; more acid flavor, such as green blackberries; there was no residual bitterness; they were folding; wrinkle free; soft to chew and thin. Regarding the acceptability test, the notes to the variable color, flavor, texture and overall acceptability were high and most judges would buy this vegetable.Item type:Item, Atividades sobre progressões aritméticas através do reconhecimento de padrões(Universidade Federal de São Carlos, 2015-09-19) ;Mantovani, Haroldo ;Salvador, José Antonio ;https://lattes.cnpq.br/2487171069472158The importance of the development of sequences that are arithmetic progressions in the high school was observed in learning situations which the students could investigate and identify patterns in numerical and geometric sequences, building the algebraic language to describe them. This work contributes for the student to build the idea of algebra as language to express irregularities, that is one of the proposed issues by the National Curricular Parameters (PCNs) for the math teaching in the fourth cycle of high school, which contrasts, nowadays, with the scarcity of activities involving observed arithmetic progressions in at least twelve years of experience as a math teacher in these cycles. The elaboration of a teaching product, in the way of activity sheets that, through the recognizing of numerical and geometric patterns, takes the student to the comprehension of the concept of arithmetic progression which could be tested through the application of these activity sheets in two classrooms of the ninth year of high school in a public municipally school. The obtained results of these applications were analyzed and compared to the previous analyzes in raised hypothesis during the elaboration of the activity sheets, using, as investigation methodology, the Didactic Engineering. The students did the activities in groups of two or three, were well motivated and participated as principal character during the application of all steps proposed in the paper, which guaranteed the good development of the activity. In according to the evaluation learning, the students reaching the proposed goals and noting that the produced teaching material works. It is believed that the elaborated material can be useful for other teachers who want to develop, in their classes, arithmetic progressions through the recognizing of patterns, adapting it to the reality of their classrooms. This work contributes hugely to the author, bringing a big professional evolution that starts with the issue choice, continued in the elaboration of the didactic sequence and the application of the activity sheets and finished with the reflection of what have been done and is registered here.Item type:Item, Síntese e caracterização de filmes finos de TiNb sobre o aço AISI 316L para aplicações biomédicas(Universidade Federal de São Carlos, 2015-09-21) ;Cruz, Ernesto David Gonzalez ;Afonso, Conrado Ramos Moreira ;https://lattes.cnpq.br/2176215981291453 ;Nascente, Pedro Augusto de Paulahttps://lattes.cnpq.br/1387043320265189Titanium and its alloys have been widely used in biomedical devices and components. The commercially pure titanium and Ti-6Al-4V (Ti64) are the biomaterials most widely used for implants, due to its characteristics regarding corrosion resistance, biocompatibility and commercial production. However, in the case of the Ti64 alloy, aluminum and vanadium present problems associated with cytotoxic effects in tissues and adverse reactions such as Alzheimer's disease and other neuropathies. The β type Ti alloys used in orthopedic devices have excellent properties such as low density, high mechanical strength and outstanding corrosion resistance, besides being biocompatible. The β phase in Ti alloys is obtained by adding alloy elements such as Nb, Ta, Zr and Mo. The coatings in form of thin films made by magnetron sputtering - MS have been successfully employed for the surface treatment of metallic biomaterials for ‘applications in the medical industry, with the advantage that low dimensionality coating does not alter the structural properties of the prosthesis to be implanted, thereby allowing improvement of their surface properties and therefore the use in the human body. A new class of Ti alloys employs niobium as a stabilizer of the β phase. The Ti-Nb binary alloys are promising candidates for biomedical applications. Therefore, an interesting option to adjust the surface feature is the thin film technology. Thus, in this dissertation, nanostructured thin films were produced by sputtering on the surface of stainless steel AISI 316L, with the purpose of analyzing the influence of niobium content on the behavior of the films. The produced films were mechanically, morphologically, crystallographically, chemically and electrochemically characterized, presenting the Ti-β phase for all the concentrations along with good mechanical properties and corrosion resistance for its potential use in the manufacture of medical implantation devices.Item type:Item, Síntese e propriedades de sílicas híbridas contendo surfactantes catiônicos(Universidade Federal de São Carlos, 2015-09-21) ;Campos, Ana Flavia Pinheiro de ;Cardoso, Dilson ;https://lattes.cnpq.br/2462847535959232https://lattes.cnpq.br/7465177122348197The control of pore geometry and pore diameter of silica mesoporous materials is necessary for application of these materials, mainly in industrial process that depends on the shape selectivity. This way, considerable efforts have been devoted to control pore structure of these materials. In this study it has been found the influence of cetyltrialkylammonium and alkyltripropylammonium (CnPr3Br, n = 14-22) surfactants in the formation and properties of mesoporous silicas and subsequently microporous silicas. Regarding the mesoporous silicas synthesized through cetyltrialkylammonium surfactants, it was observed that the silicas pore size increased and the structural ordering decreased as the head group of surfactants increased. In contrast, the increase of lkyltripropylammonium tail resulted in silicas with larger porous diameter and structural ordering. The mesoporous silica with the largest pore diameter (3,60 nm), synthesized with C22Pr3Br surfactant exhibited narrow pore-diameter distribution and a hexagonal organization characteristic of MCM-41 silica. The performance of alkyltripropylammonium surfactant as zeolitic structure directing agents was also investigated. The results showed the formation of a physical mixture between MFI and magadiite structures under different hydrothermal treatment temperatures. Only after addition of tetrapropylammonium cations to reaction mixture containing alkyltripropylammonium cations it was possible to obtain pure MFI structure. However, the presence of alkyltripropylammonium cations had strong influence on the crystals growth and consequently in the form of zeolite crystals obtained.Item type:Item, Trincamento induzido por hidrogênio em aços inoxidáveis supermartensíticos modificados pela ação de boro para aplicação em exploração de petróleo em águas profundas(Universidade Federal de São Carlos, 2015-09-21) ;Bertoldi, Daniel Brito ;Silva, Paulo Sérgio Carvalho Pereira da ;https://lattes.cnpq.br/4783514460488161 ;Ishikawa, Tomaz Toshimihttps://lattes.cnpq.br/5726055117451807The oil exploitation and production in deep water involves drilling risers with over 7 km deep. In this condition, the environments found in such wells are too adverse, acting under the exploration and production equipment, high pressures, low temperatures, severe conditions of corrosion, wear and enabling environments to hydrogen formation in the presence of H2S. Stainless steels, such as supermartensitic, duplex and super duplex have corrosion resistance and mechanical properties suitable for use in pipes in oil exploitation; however, such materials have low wear resistance. Recent studies in DEMa-UFSCar shown promising results related to supermartensitic stainless steel with boron addition, promoting the borides formation which, in turn, increases the wear resistance of these materials. In this situation, no studies have yet been performed in relation to another critical requirement in this type of request: the hydrogen permeation. It is known that hydrogen in its atomic form, when it diffuses through the steel is deleterious to the mechanical properties. Thus, a more detailed study is needed to assess the influence of this element in such properties, analyzing his performance in microstructural character. The materials produced were characterized by techniques with X-ray diffraction (XRD), optical microscopy (OM) and scanning electron microscopy (SEM). After this stage, tensile specimens were hydrogenated by electrolytic technique and tested with low strain rate. The results were compared with the same material without a prior hydrogenation and showed a major influence of the microstructure in relation to the reduction of the absolute value of some important mechanical properties.Item type:Item, Programa Vamos Cuidar do Brasil com Escolas Sustentáveis : análise de uma experiência na Escola Estadual Antonio Padilha no munícipio de Sorocaba-SP(Universidade Federal de São Carlos, 2015-09-21) ;Freitas, Maria Estela Maciel ;Freitas, Denise de ;https://lattes.cnpq.br/3330976062026878https://lattes.cnpq.br/4535850065796436Considering that the construction of sustainable social practices are central goals to guide the education of citizens in any learning context the Ministry of Education (MEC) has prepared the Progran “Let’s take care of Brazil” with sustainable schools which provides guidelines for the development of environmental education practices in schools. To participate in this program the school must present an ongoing project, addressing social and environmental issues in which the student is the subject of their learning in order to reach a personal, collective, conscious and critical training. Thus, among the objectives of this research are highlighted as follows: describe and analyze the development of the Program proposed by Ministry of Education (MEC) “Let’s take care of Brazil with sustainable schools / COM –VIDA” in school E.E. Antonio Padilha, located in Sorocaba-SP between the years 2013 and 2014, describe and analyze the practices developed by COM-VIDA and identify practices related to sustainability of those involved in the project. The methodology that leads this research is the study of qualitative case, as the case study focuses on a particular event revealing its peculiarities. For data collection were used different methods such as document analysis, participant observation, questionnaires and semi-structured interview. The Project began timidly in 2013 with the realization of practices that motivated students to participate in the IV National Children and Youth Conference for the Environment and as a result, we have the first group of students who started actions of environmental education at school. In 2014, such actions kept leading the construction of the COM-VIDA, a discussion space on environmental issues, providing carrying out actions to improve the quality of life and sustainability in the school environment. The implementation of the program and the construction of the COM-VIDA, provided to students of elementary school (6º to 9º years) practical experiences in environmental education focused on sustainability. The workshops COM-VIDA, guided in education for sustainability, the students had the opportunity to identify, discuss and propose solutions to local environmental and social problems. Among these activities are the awareness Project “Sustainability without being cliché” about the waste and proper disposal of garbage with the implementation of selective collection in our school, and growing food in the school garden. All activities were designed by the students themselves are the main protagonists in this process. Through these experiences for building theory knowledge about sustainability, it has been built their environmental identities. The move COM-VIDA has made the theme enter therein in the school environment both by students and by the managment staff causing small changes in individual and collective attitudes of the entire school community.Item type:Item, Gameta masculino de mico-leão-de-cara-dourada (Leontopithecus chrysomelas): parâmetros reprodutivos seminais e epigenéticos(Universidade Federal de São Carlos, 2015-09-23) ;Watanabe, Isabela Midori ;Valle, Rodrigo Del Rio do ;https://lattes.cnpq.br/2879780464444096 ;Peripato, Andréa Cristinahttps://lattes.cnpq.br/0657713343451089The Golden-headed lion tamarin (Leontopithecus chrysomelas) is an endemic monkey to Atlantic Forest. Nowadays, they are classified as threatened of extinction. Efforts on its conservation cover in situ and ex situ programs, and the application of the biotechnology of reproduction could assist populational manegement, hence ensuring the maintence of genetically healthy populations. Therefore, it is necessary to understand species reproductive characteristics, such as seminal parameters and variables that could influence them, and also the epigenetic mechanisms involved on genomic imprinting - once they are associated with reproductive success, and alterations on its patterns have been correlated with assisted reproduction technics. In the present study we investigated seminal and molecular parameters of golden-headed lion tamarins’ male gametes that are kept in captivity at São Paulo Zoological Foundation. Two main groups were outlined: seniors (mean age of 148.17 months; n=6) and young (mean age=50.14 months; n=6). Considering all animals, we could not find influence of weight on seminal parameters, as oppose to inbreeding coefficient variable, that showed negative correlation with total motility (R= -0.380, p<0.001), progressive motility (R= -0.443, p<0.001) and plasmatic membrane integrity (R= -0.270, p=0.018). Among seminal parameters, we found positive correlations between progressive motility and total motility (R=0.859, p=0.001), progressive motility and acrosome integrity (R=0.631, p=0.041), acrosome integrity and plasmatic membrane integrity (R=0.629, p=0.042). In addition, we found negative correlation between seminal pH and concentration (R= -0.612, p=0.029). There was only significant difference between seminal pH considering seniors and young males (t(9)=2.45, p=0.04), in which the seniors showed more alkaline pH. Molecular parameters investigated on these primates semen involved methylation analysis of two maternal imprinted genes: PEG3 and PEG1/MEST. Based on Callithrix jacchus genome, we inferred genes and its CpG islands to study them in L. chrysomelas. Through bisulfite sequencing, we investigated these regions of PEG3 and PEG1/MEST aiming to analyze putative DMRs. Among sampled animals, we could not find methylation differences on these regions, wherein all samples showed hypermethylated PEG3 region, and hipomethylated PEG1/MEST region. PEG3 CpG island is located in an exon, suggesting it is not involved in an imprinting control region. However, PEG1/MEST CpG island locates at a promoter region, showing hipomethylaton -as expected-, and align with PEG1/MEST promoter in humans, which could indicate a potential DMR. Our results are insipient to draw a conclusion about these imprinted genes in L. chrysomelas, but it was relevant as an initial approach to contribute to populational manegement of golden-headed lion tamarins kept in captivity.Item type:Item, O autorrelato de crianças expostas a contingências de competição e cooperação em atividades computadorizadas(Universidade Federal de São Carlos, 2015-09-23) ;Oliveira, Marlon Alexandre de ;Rose, Julio Cesar Coelho de ;https://lattes.cnpq.br/3386857761295187https://lattes.cnpq.br/6854732327669497The present research investigated whether contingencies of competition and/or cooperation, that could be set up on two distinct tasks (music and computer game) would affect the levels of accurate and non-accurate reports by typical children about their performances during those tasks. “Do” consisted in requiring children to play a computerized game or naming musical melodies while “say” consisted in reporting if the trial terminated with a hit or with a miss. Twelve typical children with ages ranging from seven to 11 years old were assigned to two groups with three kids for Experiment 1. Experiments 2 and 3 comprised one group with three children each. During baseline sessions from all the experiments points were presented contingent upon performances on both tasks. After the baseline, the competition contingency was on for Experiments 1 and 3 while cooperation contingency was on for Experiment 2 for its related task (music or game). Baseline contingency was still on for the other task. After some sessions the competition or cooperation contingency was set up to the other task too, thus an inter-task multiple baseline was achieved. On Experiment 3, cooperation contingency was set up for both tasks simultaneously. The points earned for correct responding on the competition contingency was exchanged by tokens that could be exchanged by gifts at the end of the session in depending of the child’s place on a rank (first place, second place and third place). The child that obtained the first place was given the chance to exchange tokens for the most preferred among the other reinforcers that were available. Children that obtained the second and third places were given chance to exchange tokes for the less preferred reinforcers only. On the other hand, the cooperation contingency specified that tokens could be exchanged by the most preferred reinforcers only if children consented in putting their tokens together. For four out of six participants the say-do correspondence decreased when the competition contingency was set up (Experiment 1). But, when cooperation contingency was set up on Experiment 2, the say-do correspondence increased for three children. It is important to notice that the increase on the levels of correspondence was observed only when cooperation contingency was set up for both tasks and not when this contingency was set up for only one task, while the other was under the same contingency as for baseline condition. Performances on the tasks and the levels of say-do correspondence were disturbed by the competition contingency during Experiment 3. This means that levels of say-do correspondence was altered while the accuracy on both tasks decreased. And the onset of the cooperation contingency resulted in increase of say-do correspondence for only one participant (music). It seems fair to assume that shifting a competition to a cooperation contingency can affect the performances on the tasks. But because of the variability on the data obtained on Experiment 2, it not possible to infer to which extent the disturbance in say-do correspondence can be attributed to shifts on contingencies or to the deterioration on task performances. In general, data from all experiments strongly suggests that the levels of say-do correspondence tend to be different when these behavior are measured under competition or cooperation contingencies. Future studies should verify the measurability of say-do correspondence in different experimental designs that could permit a more stringent experimental control over critical variables.Item type:Item, Análise proteômica e morfológica em fígado de ratos submetidos à exposição ao chumbo e suplementados com ferro(Universidade Federal de São Carlos, 2015-09-24) ;Fernandes, Mileni da Silva ;Buzalaf, Marília Afonso Rabelo ;https://lattes.cnpq.br/6461505420218183https://lattes.cnpq.br/1887340409738585Lead (Pb) is a heavy metal widely distributed in the environment, but it does not have any physiological role in the body. Due to its widespread use in the industry, it provides direct contamination of occupationally exposed people and, indirectly, through pollutants for the general. Thus, Pb contamination has become a public health problem. Studies have linked adverse health effects at low levels of Pb in the blood, even at concentrations below 10μg/dL. The effects range from cognitive impairment in children and peripheral neuropathy in adults, but there is little knowledge about its effects in the liver. It has been reported that iron (Fe) has a protective effect that can help in reducing the absorption of Pb in the body. In this sense, the aim of this study was to evaluate the protein profile and morphology in the liver of rats intoxicated by lead acetate (Pb(C2H3O2)2) submitted simultaneously to supplementation with iron sulfate (FeSO4) at 20 mg/Kg body weight. For this, 36 weanling male rats were divided into 6 groups (n=6) and treated for 6 weeks. The control group received deionized water; the first experimental group received deionized water and a solution of FeSO4 every two days; two experimental groups received 100 mg/L Pb(C2H3O2)2 in the drinking water and one of them was supplemented with FeSO4 every two days; two groups received 400 mg/L Pb(C2H3O2)2 in the drinking water, and one of them was supplemented with FeSO4 every two days. After euthanasia, blood samples and liver were collected for the analysis of Pb concentration by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Also, liver samples were collected for proteomic analysis using two-dimensional electrophoresis associated with MS (2D-PAGE-MS) and histomorphological analysis. The concentration of Pb in the blood and liver showed a dose-response effect with a reduction in 40-50% Pb in the groups supplemented with Fe (not significant). Histomorphological changes were observed in all intoxicated groups. Proteomic analysis identified 247 proteins with altered expression in relation to the control group. It was observed a decrease in antioxidant enzymes such as superoxide dismutase, catalase and glutathione peroxidase. The reduction of these enzymes leads to an increase of free radicals in the liver tissue and consequently to an in increase the levels of lipid peroxidation. The peroxidation affects the secretion of lipoproteins, mainly their release from the Golgi complex, which may have contributed to the changes observed in other proteins. The presence of Pb in some spots was confirmed by atomic absorption analysis, and this may have resulted in conformational changes that activate the protein degradation machinery. Based on the results, the present study highlights the deleterious role of Pb in the liver even at low dosage, and although Fe was associated with a reduced absorption of Pb, the results suggest that it should not be used as a prevention strategy to reduce the intoxication by Pb, since itself led to changes in the pattern of protein expression.Item type:Item, Discurso político, derrisão e heterogeneidade dissimulada na mídia contemporânea(Universidade Federal de São Carlos, 2015-09-25) ;Araújo, Lígia Mara Boin Menossi de ;Baronas, Roberto Leiser ;https://lattes.cnpq.br/4613001301744682https://lattes.cnpq.br/7893136450669304Cette thèse vise examiner la construction du discours politique dérisoire de quelques vidéos des politiques brésiliens dans le site YouTube, par moyen de l’Analyse du Discours franco-brésilienne. Pour ce faire nous avons choisi comme corpus des vidéo-montages dont les cibles de la dérision ont étés les politiques brésiliens Luiz Ignácio Lula da Silva et Dilma Roussef en tant que candidats aux élections présidentielles de 2006 et 2010, respectivement. Notre but a été de comprendre le pourquoi de la dérision portée sur eux. Cette dérision est partie évidemment des opposants des politiques cités : pour la transmettre, ils ont utilisé YouTube. Pour développer la recherche, nous avons puisé dans la notion d’hétérogénéité énonciative de Jacqueline Authier-Revuz (1990, 1998, 2004), qui est étudiée dans le Programme de Recherche en Analyse du Discours de l’UFSCar/Brésil, depuis sa parution, à la fin des années 70. Le concept en question s’est revèlé un outil de grande valeur pour notre recherche. Nous l’avons pris comme point de départ afin d’entamer une réflexion entre le discours e ses Autres constitutifs qui agissent dans le champs de l’humour politique. La notion d’hétérogénéité constitutive montrée et marquée (formulation dérivée de l’hétérogénéité énonciative) se prête bien aux recherches centrées sur des corpora politiques sérieux – par exemple, ceux qui sont véhiculés par des documents écrits, tels que la presse, les livres et les hebdomadaires. Mais, en ce qui concerne les corpora politiques non-sérieux divulgués par des sites à l’accès facile comme celui d’YouTube, site qui permet la réalisation des vidéo-montages, la notion première d’hétérogénéité de J.Authier-Revuz mérite d’être reconfigurée. Dans les cas où il est question de la présence d’un autre satirique, moqueur, qui s’insère dans le fil du discours du « je » parlant, nous voyons les aspects railleurs de ce type de discours dissimulés dans un interdiscours. Ainsi, pour étudier ou faire une réflexion sur la dérision des hommes et des femmes politiques, par moyens des vidéos-montages véhiculées par des sites comme YouTube, il faut qu’on songe à élargir la notion d’hétérogénéité et, surtout, à la considérer comme hétérogénéité dissimulée (BARONAS, 2005). Ainsi, nous avons analysé notre objet d’étude en entremêlant la description et l’interprétation, soit: nous avons réalisé une description détaillée de la matérialité linguistique, imagétique et sonore des textes sélectionnés et, en même temps, nous avons étudié la façon par laquelle ces matérialités conçoivent et interprètent les événements politiques qui circulent dans le site YouTube. Cela a été notre objet de recherche. Finalement nous avons pu vérifier la présence de l’hétérogénéité et son action dans le fil du discours dérisoire quand il avait des attaques qui rehaussaient la soi-disant incompétence ou l’alcoolisme de Lula ou l'inaptitude et la dépendance de Dilma par rapport à Lula. Ces discours ont été attestés par le moyen du discours Autre et ont été légitimés dans le lieu d’un hors- discours, d’un interdiscours articulé à d’autres sémioses – comme l’image et la bande sonore des vidéos-montages- et là ils se sont présentés de façon dissimulée.Item type:Item, Permeabilidade de filmes plásticos com nanopartículas de prata utilizados na armazenagem de morangos(Universidade Federal de São Carlos, 2015-09-25) ;Carmelo, Luis Gustavo Paulino ;Corrêa, Daniel Souza ;https://lattes.cnpq.br/0461451015026948 ;Ferreira, Marcos Davidhttps://lattes.cnpq.br/6652079760634274Due to the high postharvest losses of fruit and vegetable, the development of new technologies, aiming to reduce losses and maintain quality has greatly increased. Improved packaging can bring great benefits to the whole production chain, including enhancing shelf life, ensuring quality, and increasing product sale potential. It is important to know each packaging material properties, such as the barrier properties. Moreover, recognizing and evaluating the potential use of new technologies, such as adding metallic nanoparticles to the materials used in packaging production, can improve their properties and contribute to reduce the high postharvest losses. This research aimed to develop a simple and effective method for evaluating permeability of plastic films containing silver nanoparticles used for food storage, as well as to evaluate their permeability in regular storage conditions. To determine the permeability of plastic films, permeation chambers were designed and constructed. Those chambers allow both the gas exchange through a plastic film and permeability measurements for each specific film. Low density polyethylene (LDPE) and polyvinyl chloride (PVC) films, with and without silver nanoparticle (NpAg) addition, were evaluated. The as-prepared permeation chambers were also used to evaluate the plastic film permeability during storage of strawberries. The results evidence that the permeation chambers as well as the developed method for measuring the permeability are efficient and convenient. Such chambers can also be used for many types of polymeric films. Likewise, the developed method for evaluating the permeability in storage conditions of fruits and vegetables is effective; thus, it can assist for planning modified atmosphere packaging applied to different produces. The difference found in permeability values of the tested films under storage conditions was up to 50% when compared to the values obtained under experimental conditions. However, there were no significant permeability differences in films with NpAg when compared to films without that additive.Item type:Item, Rede de transgênicos e combate à fome no Brasil : um estudo de caso sobre a rede RENORBIO(Universidade Federal de São Carlos, 2015-09-27) ;Sobral, Vivianne Caroline Santos ;Andrade, Thales Haddad Novaes de ;https://lattes.cnpq.br/5882842888759363https://lattes.cnpq.br/0209133621640634Assuming that the use of (GMOs) in agriculture is controversial, this paper discusses one of the strongest reasons in favor of such technology: as a mean to combat hunger. To assess this joint between transgenesis and combat hunger, the RENORBIO’s researchers network (“Rede de Biotecnologia do Nordeste” - Biotechnology Network in the Northeast) has been selected to this study for stating “the use of bioscience advances to reduce hunger "as one of its interests. The present work presents a sociological point of view on the advancement of technology in agriculture, seeking to understand the progression of GM farming in crops from some reading about modern techniques. Then the question of risk and how it is produced nowadays is discussed, and, after that, the Agroecology is presented as an alternative to transgenic agricultural management. Only then, the fight against hunger is questioned, as something controversial, whose solution options depend on different worldviews. Finally, are presented some major explanations of RENORBIO, its allies, its articulations and their researches on transgenesis.Item type:Item, Os documentários musicais brasileiros : uma análise do filme Nelson Freire(Universidade Federal de São Carlos, 2015-09-28) ;Amaral, Guilherme Gustav Stolzel ;Miranda, Suzana Reck ;https://lattes.cnpq.br/8566012598222563https://lattes.cnpq.br/2459914319882874This dissertation aims to analyze the documentary Nelson Freire seeking to explore the main aspects that distinguish this work from most of the musical documentaries made in Brazil between the years of 2000 and 2013. The peculiarities of Nelson Freire were detected and problematized establishing a dialogue between the film and three of the major trends that integrate the contemporary Brazilian scene of documentaries about music: the trend of record of intimacy and the everyday life, the trend of musical performance, and the biographical trend.Item type:Item, Synthesis of new cocrystal solid form of fluconazole-fumaric acid(Universidade Federal de São Carlos, 2015-09-29) ;Owoyemi, Bolaji Charles Dayo ;Carneiro, Renato Lajarim ;https://lattes.cnpq.br/8065852319463976https://lattes.cnpq.br/2811381246113757Pharmaceutical cocrystals are multicomponent crystalline solids comprised of an active pharmaceutical ingredient (API) and one or more co-formers interacting through hydrogen bonding or other weak interactions like the π-stack and van der Waals interactions. Fluconazole (FLZ) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. It is also used to prevent and treat meningitis. Cocrystallization is an alternative approach for enhancement of drug. It can be performed using neat grinding, solvent assisted grinding, solvent evaporation, cooling evaporation and slurry cocrystallization. In this work, a new cocrystal Fluconazol-Fumaric acid monohydrate was synthesized via 1:1 stoichiometric amount of FLZ and FUM at different conditions. The characterization of the synthesized cocrystals was achieved using Raman spectroscopy, differential scanning calorimetry, powder X-ray diffraction and single crystal X-ray diffraction. The results obtained for the characterization of the samples showed some obvious differences among the spectra, diffractograms and thermograms. The single crystal X-ray diffraction analysis of the new structure shows a cocrystal where the fluconazole molecules are attached to the fumaric acid and water molecules respectively through hydrogen bonds, gave unique cell dimensions for an assumed structure C17H18F2N6O6 with a space group of P21/n, a = 17.053(3) Å, b = 5.5995(10), c=21.154(3), α = 90°, β=105.418(4)°, γ= 90°, V = 1947.3(6) Å3. This work is the first to report a monohydrate cocrystal structure of fluconazole and fumaric acid.Item type:Item, Psicanálise Existencial, Existencialismo e História : a dimensão sócio-material e a autenticidade no processo da construção de si(Universidade Federal de São Carlos, 2015-09-29) ;Moura, Carlos Eduardo de ;Monzani, Luiz Roberto ;https://lattes.cnpq.br/2036732603638197https://lattes.cnpq.br/9919710226746652Toute existence implique deux structures déterminantes dans un processus subjectif: la temporalité et l'historicité. Le "temps humain" est connu historiquement et, par conséquent, il est nécessaire d'investir dans les potentialités de la subjectivité sans négliger l'individu sous le «poids» de l'histoire. La psychanalyse existentielle, l'existentialisme sartrien et le concept de l'histoire – couvrant les aventures philosophiques de Sartre dans L'être et le néant (EN), dans les Cahiers pour une morale (CM), dans les Questions de méthode (QM) et dans le L'idiote de la famille (IF) – permettra d'établir les chemins nécessaires pour comprendre une singularité concrète dans la perspective de la relation universelle-singulier: ce est la relation entre l'individu et la société comme l'expérience de la sociabilité. Ce sujet sera perçu comme un universel singularisé, universel concrétisé (incorporé) dans une singularité concrète, auto-constituée et constitué par la réalité de leur environnement. Comprendre la subjectivité est comprendre le processus de personnalisation, identifiant subjectivité et liberté pour que l'individu ne soit jamais une chose, mais une liberté donnée pour le prisme de l'action. Je ne penserai pas ici le sujet comme « entité subjective » (substance pensante), mais considérerai l'homme sur la perspective d'un processus de subjectivation, d’une liberté existant en acte (libre) visant un but qu’il désire réaliser (concrètement, dans le monde ). 5 Le " processus de personnalisation" est acte libre – il n'y a pas comme le sujet ne parviennent pas à agir – la personalization est mouvement (tension, action) et engagement avant des situations objectives. C’est dans ce sens que le sujet sera demandé de prendre une position avant des «résistances» que le monde offre à sa liberté. Le monde, étant «celui par lequel le choix de la liberté devient, pour la liberté, destin », existera comme un en-soi, mais en relation avec le pour-soi, acquérant de sens, signification et valeur. Il sera le sujet dans la présence des faits – par la médiation des représentations de ces faits – sans qu'il devient inessentiel devant eux: l'homme est l'être dont l'apparition fait qu’un monde existe et même l'imitation intérieure de l'extériorité, même l’aliénation , ils suposse la liberté. Le pour-soi, être dans le monde et désir d'être, el cherchera à instaurer en soi-même une « immobilité » ("stabilité", "inertie", "identité", "ἕξισ"), c’est-à-dire une particularité (singularité concrète) impliquant la complexité de l’universel et se devinant, devant elle, inerte: l'individu sera la synthèse vivante de l'universel qui, à son tour, le «déterminera» (projet inauthentique, mauvaise-foi). Dans ce contexte, parler de l'intériorisation et de l'extériorisation, nous allons trouver un problème: l’extériorisation se donnera par une praxis systématisé (institutionnalisé – système normatif –, structurée socialement, politiquement et économiquement). Ainsi, la psychanalyse existentielle (comme un moyen, discipline auxiliaire, instrument), l'existentialisme sartrien et l'Histoire iront construire l'image d'un sujet qui s’efforcera de se saisir à soi-même au-delà de l’ἕξις, ou plutôt à construire l'image d’un sujet (autonome et authentique) qui sera compris dans le mouvement dialectique entre les deux pôles indissociables: la liberté et la détermination. Cette relation dialectique entre le passé et la constitution de l'avenir traduira le caractère dialectique de la situation dans la relation fondamentale entre êtres humains qui se realisent dialectiquement dans le monde de la matière humanisée. Il sera, enfin, la psychanalyse existentielle qui encouragera le sujet a passer de l’ἕξις à la praxis et de penser sa singularité concrète comme «essentiel» et ne fait pas disparaître ce vécu réel quand il connaître ou percevoir (perpétuellement) son soi: la matérialité du monde et l'Histoire ne pourront pas anéantir les vécus. De cette manière, nous ne désirons pas, au moins, de préparer une société fondée sur la auto-domestication de l'homme, mais sur sa souveraineté.