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Ações de professores de escolas regulares com crianças com transtorno do espectro autista
(Universidade Federal de São Carlos, 2016-05-25)
Gallo, Giulia Calefi
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Aiello, Ana Lúcia Rossito
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https://lattes.cnpq.br/7544189440874179
;
https://lattes.cnpq.br/7049557014338455
The main characteristics of Autistic Spectrum Disorder (ASD) are deficits in communication, socio-emotional reciprocity, non-verbal communication and development. In addition, they present restricted and repetitive patterns of behavior, interests or activities, insistence on the same subject, ritualized patterns of verbal and nonverbal behavior, fixed interest with unusual focus or intensity. Although people with ASD are considered persons with disabilities (Act No. 12764) being subject to the same laws and possess the rights to be included in regular education, it is still a very incipient practice in Brazil. Considering the ASD characteristics and their impact on interactions in the classroom and the unpreparedness of the professionals dealing with ASD child behavior characteristics in the classroom, are found in the literature the Evidence-Based Practices, identified as effective in teaching children with ASD. However, due to the lack of studies that demonstrate the use of these Evidence-Based Practices in Brazil, the aim of this study was to evaluate the practices used by regular rooms teachers in interventions with ASD children. Five teachers from two regular schools with ASD students participated of the research. Six interaction observations sessions of 40 minutes each in average were made with each of the teachers and children with ASD. Every teacher's action directed at children with ASD was dictated in low voice to the recorder. Subsequently, the speeches were transcribed and those transcriptions sought to identify the actions used by teachers based on a protocol. These observations were analyzed by the rate of responses to the applied practices. The results showed that the main behaviors issued by teachers in relation to children with ASD were general instruction to the room; direct question to the student (physically distant); direct question to the student (physically close); direct instruction - verbal cue (physically distant); direct instruction - verbal cue (physically close); Teacher provides physical assistance; Teacher provides physical tip (involves sign tip and tip by model); Teacher ignores the child's behavior; Teacher physically approaching the child; "Containment" physical (safe in the arm / hand / leg) for the child does not leave the room / wheel / activity. Only one of five teachers offered educational activities tailored to the student with ASD. Teachers use the same actions regardless of the needs of the student. Consequently, it follows the need to modify the perspectives before these children, making possible changes in the actions and procedures used with these children in the classroom to promote learning.
Estudo da eletrodeposição da liga Fe-Mo a partir de um banho à base de sorbitol. Caracterização física, química e morfológica dos eletrodepósitos Fe-Mo
(Universidade Federal de São Carlos, 2016-05-25)
Zacarin, Maria Gabriela
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Carlos, Ivani Aparecida
;
https://lattes.cnpq.br/1666217445807782
;
https://orcid.org/0000-0003-4878-9381
;
https://lattes.cnpq.br/6122251297187148
Study of the electrodeposition of Fe-Mo alloy from a sorbitol bath. Physical, Chemical and the morphological characterizations of Fe- Mo eletrodeposits. An alkaline solution for the electrodeposition of Fe-Mo alloys was developed with sorbitol as the complexing agent for Fe(III) ions. The Fe-Mo voltammetric profile showed two cathodic peaks c1 and c2 which were, respectively, associated with the reduction of [Fe(OH)2(sorbitol)2]3- to [Fe(OH)2(sorbitol)2]4- and its further reduction to Fe concomitantly with reduction of Mo oxides/hydroxides to Mo and also with hydrogen evolution reaction (HER) observed by the analysis of voltammetric curves together with the energy-dispersive X-ray spectroscopy (EDS) results. Scanning electron microscopy (SEM) of Fe-Mo electrodeposits with electrodeposition charge density (qd) of 5,30 C cm-2 and 510,20 C cm-2 potentiostatically produced, showed smooth films or with cracks, depending on the deposition potential (Ed). Energy-dispersive X-ray spectroscopy (EDS) analysis of Fe-Mo electrodeposits produced with qd of 5,30 C cm-2 showed that the Mo content varied with Ed from 4,88 wt% (Ed = -1,20 V) to 18,92 wt% (Ed = -1,80 V) and with qd of 510,20 C cm-2 from 25,38 wt% (Ed = -1,60 V) to 37,74 wt% (Ed = -1,40 V). X-ray diffraction (XRD) analysis of the Fe-Mo electrodeposits indicated the presence of Fe3Mo phase independently of Ed and qd values.
Recuperação de reservatórios eutrofizados por atividades antrópicas : estudos em microcosmos
(Universidade Federal de São Carlos, 2016-05-25)
Pantano, Glaucia
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Fadini, Pedro Sérgio
;
https://lattes.cnpq.br/3255060531838427
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https://lattes.cnpq.br/2316956259144120
The economic development of a country depends on good quality of water available, so the conservation and restoration of water bodies are strategic conditions for this to happen. However, water resources have become scarce over the past decades, in quantitative and qualitative terms. A variety of human activities have caused serious problems to the aquatic environment, and eutrophication is one of the most responsible for the degradation of the quality of water bodies, mainly caused by the artificial enrichment of nutrients, especially phosphorus and nitrogen. There are currently two contrasting scenarios: the excessive presence of phosphorus in aquatic ecosystems and, the depletion of phosphate rock deposits, which endangers the water security and the global food security. In this context the development of technologies aimed at the recovery of the quality of aquatic ecosystems and phosphorus contained in these compartments is of fundamental importance, since the global stock of phosphate rocks is a finite resource and may be close to being exhausted. Various technologies for the remediation of eutrophic environments have been studied, however none of which aims to reuse of phosphorus in agriculture. Thus, the aim of this study was to evaluate the sawdust as biosorbent material to phosphorus aiming the recovery of the quality of water resources and its later use as fertilizer in agriculture. The experiments were conducted in two stages, first were assembled microcosm with water and sediment samples from eutrophic reservoir Ibirité/MG, the total incubation time was 159 days, in this time various parameters (physicochemical and chemical) were monitored in the water column, interstitial water and sediment. After the end of this first experiment arose any question about the phosphorus adsorption in sawdust, what motivated the development of a new experiment with samples of the Barra Bonita/SP. This experiment was performed with sterile and non-sterile samples as well as that had or not a previous addition of iron in the sawdust, the incubation time was 240 and 247 days, respectively for non-sterile and sterile experiment. The results of the first experiment (Ibirité) showed that there was a reduction of 90.5% of orthophosphate in the water column of the microcosms and sawdust adsorbed 16.2 μg g-1, this adsorption occurred mostly after 113 days of incubation. In the second experiment results showed that prior to addition of iron not conducive to increased adsorption in the non-sterile experiments, and the main adsorption mechanism may be not via the action of bacteria oxidizing Fe (II). The higher adsorption in the second experiment took place in sterile microcosm, where sawdust adsorbed 66.9 μg g-1 in the period of 247 days. Knowing that the success in the recovery of water bodies depends on the reduction of external phosphorus sources, the studied technology has a good potential application as a remediation technique and phosphorus reuse as fertilizer, mainly because it is an inexpensive technique and easy to use.
(Des)construindo persona
(Universidade Federal de São Carlos, 2016-05-25)
Schwarz, Pedro Max
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Monzani, Josette Maria Alves de Souza
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https://lattes.cnpq.br/0505156751073470
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https://lattes.cnpq.br/2805976848926110
The purpose of this research is to make an analysis of the themes and aesthetics of the film Persona, from Ingmar Bergman, 1966. The first chapter is my analysis of the work, following the model of the writers Anne Goliot-Lété and Francis Vanoye, and the second chapter discusses the critical texts, analysis and interviews connected to the film. I also discussed the difficulties related to the interpretation of movies, and I tried in my own analysis to be very close to the movie itself, despite the tentations to invent more.
Rede temática de atenção às urgências e emergências na perspectiva de gestores hospitalares
(Universidade Federal de São Carlos, 2016-05-25)
Fonseca, Erika da
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Lima, Valéria Vernaschi
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https://lattes.cnpq.br/7945420582384290
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Sampaio, Sueli Fatima
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https://lattes.cnpq.br/0737750473446351
This study aims to analyze the integration of hospitals in the Thematic Network of Attention to Emergencies and Emergencies of the Regional Health Department III of the State of São Paulo - Heart region, from the perspective of their managers. Therefore, the research had based on the assumptions of qualitative research, using semi-structured interviews as the main tool for data collection and content analysis technique for the analysis of interviews. The population consisted of five hospital managers from the four participating municipalities. By analyzing, the data from the reports of managers emerged two categories of analysis: potential (1) and limitations (2). From this definition and following the axes of health care management (axis 1), health management (axis 2) and management in education (Axis 3), subcategories were organized; being identified in the potential three (axis 1), two (2 axis) and two (axis 3) and the limitations two (axis 1), three (axis 2) and (3 axis). For this research, the following considerations had obtained the study allowed not only to identify the perception of managers regarding the Thematic Network Emergency Department and its relationship with its equipment manage, but also the possibility of identifying strengths and weaknesses for effectiveness of proposals proposed regarding the network design. It confirmed the need for strategies to boost the creation / consolidation of the Thematic Network Emergency Department in the Region Heart. Finally, the continuous and permanent reflection of professional, local, municipal, state and federal managers can be a strategy for the consolidation of the Thematic Network.
Lipases imobilizadas em suportes híbridos como biocatalisadores para a produção de ésteres de açúcares
(Universidade Federal de São Carlos, 2016-05-25)
Vescovi, Vinicius
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Mendes, Adriano Aguiar
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https://lattes.cnpq.br/2926571414651131
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Tardioli, Paulo Waldir
;
https://lattes.cnpq.br/0808991927126468
The use of lipases in large scale processes is limited due to their high cost. The reuse of the catalyst can contribute to make the enzymatic process more attractive. Hydrophobic supports are the mostly used for lipase immobilization, due to the mechanism of interfacial activation in the presence of hydrophobic interface. However, enzyme physically adsorbed to the support does not allow high operational stability. Therefore, in this work was evaluated the immobilization of commercial lipases from Candida antarctica type B (CALB), Thermomyces lanuginosus (LTL) e Pseudomonas fluorescens (LPF) on hybrid supports, that enable the hydrophobic adsorption, followed by covalent linkage between the adsorbed enzyme and the activated support. Silica was activated with trietoxy(octyl)silane (OCTES), (3-aminopropyl)trietoxysilane (APTES) e 3-glycidyloxypropyl)trimetoxysilane (GPTMS), aiming to produce supports with different functionality, as following: silica containing octyl groups (octyl-silica, OS), octyl and aldehyde groups (octyl-silica-glyoxyl and octyl-silicaaldehyde, OSGlx and OSGlu, respectively), and silica containing octyl and epoxy groups (octyl-silica-epoxy, OSEpx). From adsorption assays using the hydrophobic dye Rose of Bengal it was found that the modification of the silica with OCTES significantly increased the hydrophobicity of all the supports. Silica modified with OCTES groups showed to be 4 times more hydrophobic than non-modified silica. The support OSGlu yielded more active CALB biocatalyst, while OS yielded more active biocatalysts prepared with PFL and TLL. All the biocatalysts showed high stability in tert-butanol, specially CALB immobilized on OSGlu (OSGlu-CALB), maintaining 95% of its initial activity after 168 h at 60 ºC. CALB-OSGlu was successfully used in the synthesis of fructose oleate at 55ºC, yielding up to 70% conversion after 9 cycles of 6 hours, while the commercial biocatalyst Novozyme 435 retained around 53%. TLL and PFL were used in the synthesis of fructose oleate at 35ºC in presence of different amounts of water. All biocatalysts showed excellent performance in the ester synthesis when small amount of water (1%, v/v) was added to the organic phase, except for the lipases immobilized on silica modified with octyl and epoxy groups (OSEpx). Small amount of water increased around 5-times the ester productivity compared to reaction without water. Conversions around 70% were achieved at low temperature (35ºC) and short time of reaction (30 min). These results represent an advance in this field from of industrial point of view, where productivity is a relevant parameter for large-scale processes. Finally, porcine pancreatic lipase (PPL) immobilized on OS was used in the synthesis of xylose oleate and xylose caprilate, because it is the most inexpensive lipase commercially available. The results showed to be promising, because conversions around of 70% were achieved after 2 h of reaction at 60 oC. Generally, this work showed that the chemical modification of the silica surface with different active groups allowed the preparation of biocatalysts with different microenvironment, which exhibits an important role in the activity and stability of the immobilized enzymes. Besides, the biocatalysts prepared in this work showed excellent performance and operational stability in syntheses of sugar esters, showing to have potential for industrial application.
O intérprete de libras no contexto de conferência : reflexões sobre sua atuação
(Universidade Federal de São Carlos, 2016-05-25)
Santos, Kátia Andréia Souza dos
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Lacerda, Cristina Broglia Feitosa de
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https://lattes.cnpq.br/9468232016416725
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https://lattes.cnpq.br/5119057767581541
The Brazilian Sign Language (Libras) interpreters are already recognized in the country, its importance has been valued in academia and the professional is increasingly sought in the labor market due to greater integration of the deaf in society. Thus, this research addresses issues related to the interpretive act and it aims to better understand the Libras interpreter's role in the conference context. To this end, a descriptive qualitative approach was developed using the method of simple self-confrontation. Three professional Libras interpreters who worked in a national scientific event in the field of special education agreed to participate in this research. The data collection was made individually, during and after the interpretative act by video, and the speeches of the participants then transcribed for analysis. The study showed that conferences are an extremely complex context of action for these professionals, regarding: (i) time, which is limited and generates the need for interpreters take quick decisions to do a good job; (ii) exposure, which due to the prominence given to this professional, that usually stay next to the speaker and under the eyes and judgments of the audience must learn to deal with constraints; (iii) position, which complicates the work of the interpreter, because they need to see the slides projected behind them and the speaker gestures; and (iv) preparation, so important for the appropriate transmission of ideas during the interpretative act, but cannot be always do by the interpreter for various reasons. In addition, it stands out as the method of simple self-confrontation proved to be an interesting tool to self-reflections of the participants of this study.
Linha de montagem para a produção de habitações em light steel frame : projeto e otimização
(Universidade Federal de São Carlos, 2016-05-25)
Vivan, André Luiz
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Paliari, José Carlos
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https://lattes.cnpq.br/9387796929252598
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https://lattes.cnpq.br/7191823459864289
The Construction Industry (CI), regarding the production of single-family housing in Brazil, is still characterized by the use of techniques and technologies that are highly dependent on knowledge and manpower experience. Thus, in most projects involving the construction of single-family housing, there are handcraft features when the building site is understood as a production system. Thus, it is common to observe the pathological manifestations appearance in post-occupational analysis, in addition to non-compliance with deadlines and budgets. In this sense, this thesis suggests that the CI breaks with some technical and cultural paradigms from the use of an industrialized building system, such as Light Steel Frame (LSF) and from the use of assembly lines, focusing the industrialization of singlefamily housing production. This proposal is based on four steps involving theoretical and experimental approaches. The theoretical approaches involved the structuring of a systematic literature review, which were identified gaps in scientific knowledge and the research hypothesis, besides the development of basic theoretical framework, the product definition and production system design. The experimental approach was represented by activities related to computer simulation of the production system and its subsequent optimization. The computer simulation was performed with the ProModel® software where was simulated the production of five hundred housing units from the programming logic of the designed system. Seven scenarios were simulated, with the results of its simulation it was possible to identify the most efficient configuration from optimizing the use of some resources, identified by layout B. In addition, the main results of the simulations show that it is possible to assembly the housing unit designed at 11.14 hours, with a cycle time of 5.56 hours, with the settings of scenario seven. The purpose of this thesis and the results can be considered relevant because promote innovation for both the consumer market and to the academy, since it deals with concepts little used or known in the CI. It also enables greater speed and volume of production, facing the Brazilian housing deficit, with significant quality improvements.
O trabalho como princípio educativo : uma análise do Programa Ensino Médio Inovador (ProEMI) nas escolas públicas de Sorocaba-SP
(Universidade Federal de São Carlos, 2016-05-30)
Dias, Camila Mantovani
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Ferreira Junior, Amarilio
;
https://lattes.cnpq.br/0748545841167046
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https://lattes.cnpq.br/4170767206090346
This dissertation is as study on the Ensino Médio Inovador Program (ProEMI), created by the Federal government by ordinance n.º 971, from October 9, 2009. The aim is to debate if this educational policy strengths the early professional development of young students who attend the regular public high schools. Work here is understood as an educational principle, and this study try to investigate the ProEMI in face of the historical and social necessity involved in currently high school education and in the whole youth formation nowadays. The first part focus on the Marxist theoretical and methodological references regarding to the fields of work and education, specially the contribution of the Italian communist Antonio Gramscie. The second part presents a bibliographic review of the history of the high school in Brazil. The objective is to understand how education was structured, its identity and how high school education posited itself in face of the social conflicts and the demands for education and training in the productive world. The second chapter also analyzes the legislation related to the ProEMI, mainly focusing on the first decade of the 21st Century. At the end of this study, the last and final chapter presents a field research at Sorocaba School Board (SP). Three public schools were selected by the grades obtained in the IDESP (Educational Development Index of the State of São Paulo). The research techniques employed were questionnaire and interviews with the school management body and students in the 12th-grade where ProEMI takes place. This study intend to contribute to the unveiling of the public policies for high schools, relating to the necessities involved in this stage of youth training and formation, based on principles of Brazilian theorists in Education, who keep alive the spark of a school for all and of high-quality.
Promocão do letramento emergente de crianças com Síndrome de Down
(Universidade Federal de São Carlos, 2016-05-30)
Dias, Mirian Vieira Batista
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Rose, Tânia Maria Santana de
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https://lattes.cnpq.br/3726292298571344
;
https://lattes.cnpq.br/8831040739825039
The literature highlights the importance of Emerging Literacy and the development of knowledge about writing and its functions acquired by children in the period of early childhood education for success in literacy. The research shows that, through contacts with actions of reading and writing conducted by adults, young children with typical development and non-typical develop: 1) interest in books; 2) interest in stories read by the adult; 3) active participation while reading; 4) knowledge about the book handling; 5) direction of reading; 6) concepts about writing conventions; 7) distinction between written and unwritten; 8) functions of writing; 9) recognition of global and common words in the environment; 10) recognition of the first name; 11) reading pretends; 12) tracing and evidence of the alphabetic foundation. The main objective of the study was to examine the development of knowledge, skills and attitudes of the emerging literacy of students with intellectual disabilities exposed to a contact experience with reading books and encouragement to participate in activities that stimulated the different components of emergent literacy. This study is characterized as a single subject design. Study participants were two students with intellectual disabilities and Down syndrome attending the resource room of a public school in ordinary school with kindergarten rooms. The activities were conducted individually by the proposer of the study. Participant 1 had the opportunity to participate in 15 sessions of weekly activities and Participant 2 in 11 stimulating sessions, of different components of emerging literacy. As a result of the program, the study participants were able to become familiar with the components of emergent literacy through shared reading, the autonomy to choose the books, hear a variety of stories with effective participation, and participation in activities that contributed to the understanding of conditions which appears necessary for the acquisition of emergent literacy components occurred during the sessions. The participants demonstrated a reduced evolution relative to the emerging literacy regarding the writing activities, which were not present in the repertoire of the participants at the beginning of the intervention.They identify conditions that may have contributed to the results that were not consistent with results obtained in similar studies.
Trabalho pedagógico na educação especial: o professor de sala de recursos e sua implicação na escolarização dos alunos com baixa visão
(Universidade Federal de São Carlos, 2016-05-30)
Oliveira, Lígia Maria Nogueira
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Caiado, Kátia Regina Moreno
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https://lattes.cnpq.br/0803778280883949
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https://lattes.cnpq.br/2911367601684468
Confirmação matemática do efeito Aharonov-Bohm no modelo sem interação com a fronteira do solenóide
(Universidade Federal de São Carlos, 2016-05-30)
Romano, Renan Gambale
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Oliveira, César Rogério de
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https://lattes.cnpq.br/5485204156806697
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https://lattes.cnpq.br/2317413965575635
We study the Aharonov-Bohm effect model by adding a scalar potential in the initial Hamiltonian. Using known techniques of quantum confinement, we show that under certain conditions of divergence on this potential, the family of self-adjoint extensions is reduced to a single operator, which would then be the Schrödinger operator for this situation. The lack of boundary conditions to define this operator is interpreted as no particle interaction with the boundary of the solenoid. We checked the possible manifestation of the Aharonov-Bohm effect in this model without interaction with the solenoid border by studying the dependence of the first eigenvalue associated with the Schrödinger operator with respect to a parameter directly related to the magnetic flux by the solenoid. We have shown that this dependence is non-trivial and periodic, which strictly confirms the Aharonov-Bohm effect for this situation. We also study some particular cases whose explicit solution can be achieved, the solenoid with zero radius in a limited and unlimited region of the plane.
Contribuições de encontros de diálogo ao longo do pré-natal
(Universidade Federal de São Carlos, 2016-05-30)
Corrêa, Carla Regina de Almeida
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Wernet, Monika
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https://lattes.cnpq.br/6056127658896265
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https://lattes.cnpq.br/3124744942291736
The gestation period is known as a time full of great transformations, such as physical, hormonal or emotional ones. In this period, most women experience some anxiety about themselves and the baby care, making it a space favorable to achieve and/or modify knowledge about it. This study had as object “A meeting for some dialogue and its repercussion to maternity”; and, based on this, it proposes to understand the influence of these dialogues during the prenatal in the parentally process, paying attention to the use of a social network. The theoretical reference adopted is George-Hans Gadamer‟s Hermeneutics and the methodological reference is the Thematic Content Analysis.Data were collected by a semi-structured questionnaire, obtaining a deep and complete narrative based on the starting question “Tell me about the opportunity to talk during the prenatal. What was your perception?” Participated of the study seven women who went to the meetings more than three times and accepted to take part of it. The meetings for some dialogue occurred from October, 2014 to August, 2015, in the countryside of a city in the state of Sao Paulo, Brazil; data were collected in a period between forty-five and sixty days after the childbirth. Data analysis showed two themes: “Informational Support” and “Emotional Support and Acknowledgment of Themselves”It was identified that the participation inthese meetings for some dialogue during the prenatal was important for women who built a dialogic movement in the acknowledgment of themselves and the others as an emotional and informational social support. These dialogues emancipate the pregnant mothers to take decisions on how to take care of their children, promote a social network increase and contribute for the acceptanceof the support received.Besides, these meetings permitted that these women, individually, developed the process of parentally building, recognizing themselves as mothers and creating opportunities for the fathers approaching in this auto recognizing movement.
Clínica ampliada na infância : a compreensão de profissionais da estratégia de saúde da família
(Universidade Federal de São Carlos, 2016-05-30)
Romano, Diana Carla
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Carbol, Maristela
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https://lattes.cnpq.br/9852217198710064
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Joaquim, Regina Helena Vitale Torkomian
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https://lattes.cnpq.br/7719481657895650
The crisis in care management is evident over the new challenges of modern epidemiology, which comprises the complex phenomenon that links the biological to the psychological, social and ecological factors. Hence, the "Clinica Ampliada"(CA) is committed to offer high standards on health care considering the subject as a whole. The childhood years were chosen due to the relevance of this phase to the development of society. The aim of this study is to acknowledge the "Estratégia de Saúde da Família" team members perception about "Clinica Ampliada" over childhood. This is a scoping, descriptive study with a qualitative approach. Participants are nurses, doctors, dentists, nurses assistants, community health workers and dental assistants of family health units. For data collection a semi-structured interview guide was utilized, and from the CA theoretical foundation, the analysis by thematic categories was conducted. From a total of 32 participants, 50 per cent of the professionals have between 25 and 35 years of age, mostly female and work at USF more than five years. It was found that 19 subjects have already heard about the CA term and professionals with higher education were the ones who described the concept with more facility and coherence. A gap was evidenced between what they noted as CA and what they do or can do in their day to day routine. Therefore, the subjects pointed out to elements that contribute to the implementation of CA in childhood, such as enlargement of the object's concept, health care model, support management and emotional support. The participants recognized the positive contribution that the ESF scenary provides for the expansion and clinic better quality, mainly for working with the principles of comprehensive care, teamwork, home care and intersectionality. It was concluded that the path for the CA consolidation in childhood is the strengthening of child role and EPS.
Desenvolvimento e validação de um novo método analítico para quantificação de resíduo de eprinomectina no leite bovino
(Universidade Federal de São Carlos, 2016-05-30)
Ré Filho, Antonio Oscar
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Lopes, Norberto Peporine
;
https://lattes.cnpq.br/1357061371579771
;
Montanari, Carlos Alberto
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https://lattes.cnpq.br/9200533791228786
Brazil is one of the biggest producers and consumers of milk around the globe. To ensure the productivity and profitability of the cattle, the use of antiparasitic plays an important role in strategic control of worm infections in dairy cows. The justification for such effect on milk’s production is based on the reduced appetite of infected animals caused by gastrointestinal nematodes. As known, any reduced appetite has a major impact on the production of dairy cow. Eprinomectin is an antiparasitic that has been used in dairy cows, however, the use of this product should be done properly respecting its withdrawal period, so that it is impossible to find its residue in milk above their Maximum Residue Level (MRL). In order to ensure consumer’s safety, national and international agencies have set Maximum Residue Level. Thus, this study aims at the development and validation of an analytical method for the determination of Eprinomectin residue in milk (EPRI) by liquid chromatography coupled with sequential mass spectrometry with electrospray ionization (LC-ESI-MS / MS), and subsequent determination of the withdrawal period of the veterinary drug from Ouro Fino Saúde Animal. The residual depletion study is necessary for the veterinary medicinal product registration in the Ministry of Agriculture, Livestock and Supply (MAPA). Ivermectin (IVER) was used as internal standard in the analytical method. In development of the extraction method it out a comparative study was carried out in terms of recovery between QuEChERS and liquid-liquid methods with low temperature partition (ELL-PBT). The optimization of the two extraction methods was made by factorial design. The best recovery was observed in ELL-PBT method. Acetonitrile was used as extractor solvent, the partition phase between organic and aqueous phase was made by freezing the samples at -20 ° C for 12 hours and in the clean up step hexane was used as solvent. The analytical validation parameters will be evaluated according to standards established by the Guarantee Manual of Analytical Quality of MAPA (MAPA/ ACS, 2011). The method was linear for eprinomectin in the range of concentration of 10.0 to 50.0 ug L-1, the linear correlation coefficient (r) was in accordance with the guidelines for bioanalytical methods (r ≥ 0,98). The repeatability was evaluated in three levels of fortification being performed for three consecutive days. Good intra-laboratory reproducibility was obtained, with coefficient of variation (CV) of 8,6 % for the fortification of MRLS. The recovery was above 80.0% for the three levels of fortification, being of 94.8 % for the level of MRLS. Satisfactory values for the decision limit (CCα) and detection capability (CCβ) were obtained, being CCα 22,1 µg L-1 and CCβ 24.2 µg L-1. The limits of detection (LOD) and the limits of quantification (LOQ) were determined from the data of the calibration curve. The LOD showed the value of 1.9 ug L-1 and the LQ of 5.9 UG L-1. Thus, the value of LOQ was below the MRL and of the first level of concentration of the analytical curve.
Parametric and semi-parametric cure rate models with spatial frailties for interval-censored data
(Universidade Federal de São Carlos, 2016-05-31)
Bao, Yiqi
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Cancho, Vicente Garibay
;
https://lattes.cnpq.br/3503233632044163
;
https://lattes.cnpq.br/9021028070787191
In this thesis, we extend some flexible cure rate models, such as the geometric, negative binomial and power series cure rate models, to allow for spatial correlations by including spatial frailties for the interval censored data setting. Parametric and semi-parametric cure rate models with independent and dependent spatial frailties are proposed and compared. The proposed models encompass several well-known cure rate models as its particular cases. Since these cure rate models are obtained by considering that the occurrence of an event of interest is caused by the presence of any non-observed risks, we also study the complementary cure model, which arises when the cure rate models are obtained by assuming the occurrence of an event of interest is caused when all of non-observed risks are activated. A new measure of model selection, based on the notion of predictive loss paradigm, for the interval-censoring data is also proposed. The MCMC method is used in a Bayesian inference approach and some Bayesian model selection criteria are used for model comparison. Moreover, we conduct an influence diagnostics to detect possible influential or extreme observations that can cause distortions on the results of analysis. Finally, the proposed models are applied to analyze a real dataset from a stop smoking study.
Nas tramas da revitalização : conflitos e movimentos na zona portuária do Rio de Janeiro
(Universidade Federal de São Carlos, 2016-05-31)
Costa, Flávia Carolina Da
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Toledo, Luiz Henrique de
;
https://lattes.cnpq.br/5366260223109463
;
https://lattes.cnpq.br/3624633716376418
This thesis focuses on the observation and analysis of the connections among memory, conflict and politics in social network associations, neighborhoods and local sociabilities in the context of the urban “revitalization" in the port area of Rio de Janeiro. Presuming that a story is an individual expression limited by a "general discourse" that classifies feelings, understandings and significations of experience from a dominant culturally provided structure, this thesis is guided by the understandings of a symbolic universe based on memories that combine past and present with official and non-official perceptions of the city, told in multiple ways by the interlocutors of this research. Throughout the study the term "revitalization" is analyzed according to circumstances in which dweller and association categories were observed in the course of fieldwork as a constant "movement" of different artistic, political and cultural investments in the context of social transformations. The nonfixity of the resident category is due to the notion of "testimonial memories" and ethnographically understood as the operator of a system that activates relations and "ways of inhabiting" in the port area, primarily from a political point of view.
A influência da morfologia do MgO nas propriedades catalíticas do SiO2/MgO para a formação de 1,3-Butadieno a partir de etanol
(Universidade Federal de São Carlos, 2016-05-31)
Souza, André Machado Ribeiro de
;
Bueno, José Maria Corrêa
;
https://lattes.cnpq.br/0157452280626031
;
https://lattes.cnpq.br/8321288977088061
Ethanol has been largely studied in the past few decades as a substitute to fossil fuels in the synthesis of a large variety of chemicals. 1,3-Butadiene, one of these compounds, is an important chemical intermediate and also a monomer for some polymers such as synthetic rubbers. It is mainly produced as a by-product from naphtha steam cracking, which has ethylene as the major product. As crude oil prices have been fluctuating in the latest years and with the discovery of shale gas in the US, a promising source for ethylene, there is an urgency for developing alternative routes to produce 1,3-Butadiene. Several studies have been carried since the 1940s trying to create viable processes and using many different catalysts, indicating MgO/SiO2 - with or without the addition of transition metals - as being the most promising one. However, there is still a lot of missing information on how does the interaction between silica and magnesia affect the yields and selectivity. In the present work it was studied how the morphology of the MgO affects the interaction with the SiO2 to generate active sites. The MgO with different morfologies were synthesized and then wet-kneaded with SiO2 to provide catalysts with different MgO/SiO2 ratio. The samples were calcined and catalytic tests were carried out. X-Ray Diffraction, Temperature Programmed Desorption of CO2 and Scanning Electron Microscopy were also performed on the catalysts. The obtained micrographs for the oxides confirmed the successful preparation of different morphologies, and the results for catalytic tests showed that there is some influence from the morphology over conversion and selectivity of SiO2/MgO. For the MgO morphologies at the temperature of 425 oC, ethanol conversions between 11.7% and 21.9% were obtained for different samples, with selectivities for butadiene between 5.6% and 30.4%. For SiO2/MgO catalysts, in the same temperature, different yields were obtained for distinct morphologies and Mg:Si ratios. For 3:1 catalysts, yields between 21.5% and 34.3% were observed, while for 7:1 catalysts the yields vary from 18.5% to 35.4%. Catalytic properties could not be clearly correlated to the TPD-CO2 and specific surface area, indicating that they are dependant on a complex set of factors, among them the accessibility of the surface for the SiO 2 contact. Variation of the silica content for all morphologies showed that the SiO2/MgO ratio is extremely important for the preparation of active and selective catalysts for the production of 1,3-butadiene.
Entre fios e teias de formação : narrativas de professoras que trabalham com matemática nos anos iniciais – constituição da docência e os desafios da profissão na educação pública estadual paulista frente aos programas de governo no período de 2012 a 2015
(Universidade Federal de São Carlos, 2016-05-31)
Montezuma, Luci Fátima
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Passos, Cármen Lúcia Brancaglion
;
https://lattes.cnpq.br/2297203444364327
;
https://lattes.cnpq.br/6424535625288505
This text comes from a doctoral research, with a qualitative approach, which included the participation of nine polyvalent and experienced teachers who teach math to the early years, work in São Paulo State Public Education and, over the years of 2012 to 2015, produced autobiographical narratives, written and/or oral, from narrative interviews, considering the experienced formative processes throughout their life stories, with focused eyes mainly for mathematics, facing the implementation of government programs with focus in this discipline in the early years: Mathematics Education for the early years-EMAI and National Pact for Literacy in the Correct Age-PNAIC-Mathematics. Considering that the way of "being" a teacher is related to the established culture and to what they experienced, the aim of this study was to understand how is the teaching constitution process of experienced teachers who teach Mathematics to the early years, facing the government programs that impacted the teaching of Mathematics in the early years in the São Paulo State Public Education in the period between the years of 2012-2015, entitled of EMAI and PNAIC Mathematics, trying to understand the teaching professionally constitution process of collaborators teachers over time and to raise evidences of professional development. In this context, this work tried to answer the investigative question how gives the process of teaching formation of experienced teachers, facing both programs, and find out what impacts were generated in the teaching practice of them, since such programs, substantially interfere in the daily life schools. The theoretical basis that supported the analysis are the narrative and autobiographical researches, mainly in Bolivar, Domingo and Fernandez; Connnelly and Clandinin; Josso; Passeggi, Souza and Vicentini; and the formation training of teachers in: Mizukami et al.; Tardif and Shulman. The analysis of the narratives reveals professional development evidences of teachers from established programs, but indicates that, in the practice of the classroom, with the students, in certain situations, in front of their views already entrenched historically, teachers came into conflict with the theoretical and methodological guidelines proposed, and they take practices that could be considered creative insubordination, when the teacher dares to create and dares in teaching with the desire to promote learning in which students attribute meanings to the knowledge. The analysis reveals that, as pointed out in the field training of teachers researches, the act of teaching is to make choices in full interaction with students, starting with the knowledge of teachers, their conceptions, the ethic and the professional commitment that they have with the exercise of being a teacher. It was also observed that teachers felt discomfort in front of professional precariousness, leaving them with fear about how will be the future of this category and sometimes even a teacher unease.
HGPRT: enzima recombinante de Schistosoma mansoni e sua ação na imunoterapia durante a esquistossomose murina
(Universidade Federal de São Carlos, 2016-06)
Fragelli, Bruna Dias de Lima
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Pereira, Humberto D'Muniz
;
https://lattes.cnpq.br/8681619250791832
;
Anibal, Fernanda de Freitas
;
https://lattes.cnpq.br/4918261968772806
Schistosomiasis is a chronic parasitic disease and neglected, caused by the flatworm Schistosoma sp and affects 240 million people around the world. In Brazil is considered expanding and reaches 19 states. Schistosoma mansoni can evade the host immune response in a way not fully understood. Thus, the search for new drugs for the treatment of schistosomiasis tends to become a new alternative for the control of infections caused by this parasite. The purine bases biosynthetic pathway is a key to drug development, because it is directly related to the maintenance of DNA and RNA synthesis. The recombinant enzyme Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) has an important function in the way of salvation of purine bases. Therefore, this study aimed to evaluate the potential of recombinant enzyme HGPRT treatment (Immunotherapy) in experimental schistosomiasis. The methodology used was Immunotherapy using the enzyme of S. mansoni recombinant HGPRT to treat female mice of the strain Swiss infected with S. mansoni with 3 doses after 28 days of infection. Later it was made the evaluation of egg in feces by the method Kato - Katz, cell count of peritoneal cavity lavage and blood, perfusion for the recovery of adult worms’ door-hepatic system and intestinal mesentery. The results were analyzed using statistical program GraphPad Prism 5.01. Infected animals and treated with the enzyme showed a marked decrease in the number of eggs, which is critical to reducing the morbidity related to parasitosis. There was also a reduction of the parasitic load and the number of eosinophils. The results demonstrate that treatment with recombinant S. mansoni HGPRT enzyme has potential for treatment of schistosomiasis. Thus, these results need to be better investigated to understand which mechanisms are involved in the control of schistosomiasis.