Browsing by Issue Date, starting with "2017-05-09"

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Efeitos de um derivado semissintético do [6]-gingerol na autofagia e apoptose em células de câncer de mama
(Universidade Federal de São Carlos, 2017-05-09)
Dulcey, Liany Johanna Luna
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Cominetti, Márcia Regina
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https://lattes.cnpq.br/3725318894555272
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https://lattes.cnpq.br/1841833705087719
In this work, we describe a semisynthetic derivative of [6]-gingerol called SSi6, which induces cytotoxic effects on the MDA-MB-231 breast tumor, showing a greater selectivity for these cells when compared to the non-tumor MCF-10A , In addition, the substance was determined to induce autophagy and apoptosis in tumor cells, with less pronounced effects on non-tumor cells. The coexistence of both events (autophagy and apoptosis) was demonstrated by flow cytometry, which evidenced an increase in the percentage of apoptotic cells after 24 hours of treatment, these results were also confirmed by the analysis of the gene and protein expression of caspase-3 using Real-time PCR and western blotting respectively. Induction of autophagy in SSi6-treated cells has been demonstrated through acid vesicle organelle (AVOs) detection assays and the expression of genes encoding the LC3-I and II microtubule-associated proteins to quantify the abundance of autophagosomes in MDA-MB-231 cells. Thus, these results indicate that SSi6 has the potential to induce autophagy and apoptosis, as well as antitumor and antimetastatic properties in MDA-MB-231 breast tumor cells.
Regressão não linear quantílica para classificação de sítio em povoamentos de Eucalyptus sp.
(Universidade Federal de São Carlos, 2017-05-09)
Santos, Carlos Juliano
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Thiersch, Cláudio Roberto
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https://lattes.cnpq.br/8791966697254106
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https://lattes.cnpq.br/6499460352099237
The productive capacity is conventionally estimated by anamorphic or polymorphic calculated site curves; however, these curves have some limitations. Due to these limitations, the objective of this work was to evaluate the creation of growth curves for site classification by the nonlinear quantile regression method and to compare them with the curves generated by the algebraic difference method. The database was collected in two mesoregions of the state of São Paulo (Paulista and Bauru Metropolitan Macro), with 460 measurements in 98 plots with distinct periods in Eucalyptus sp. The site curves were adjusted according to the Chapman-Richards model using the algebraic difference method for anamorphic and polymorphic curves and nonlinear quantum regression (RNLQ). The results of this work allowed to conclude that the site curves adjusted by the RNLQ method are superior to the curves generated by the algebraic difference method by graphical analysis of the residuals with smaller ranged of the errors and greater homogeneity and residual standard error with lower values in the classes in general.
Propostas de pagamento no estudo de matemática financeira : análise de uma abordagem prática
(Universidade Federal de São Carlos, 2017-05-09)
Francisco, Marcelo Sabbadini
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Malagutti, Pedro Luiz Aparecido
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https://lattes.cnpq.br/5462523657624050
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https://lattes.cnpq.br/9478680093249519
The objective of the project and research was to apply and conjecture about a practical approach to the study of payment methods, using commercial proposals of students' daily routine of a technical course in the management area. Assessing the historical and conceptual aspects, as well as associating them to students' daily life, in order to assist the student and the technical future in their future commercial transactions, whether private or professional, and enable them to conceptually and critically evaluate the methods of payment offered in the acquisition of a property, were the main strands developed in the application of the research proposal, as recommended by various scholars in the area of financial education, among them GRANDO and SCHNEIDER (2011). The work was developed, according to the theoretical presuppositions of didactic engineering, in stages, among them the study of conceptual and historical aspects of the amortization system, analysis of everyday situations and the application of questionnaires. The researcher professor conducted the study in the 1st module of technical course in finances at a state technical school in Jaú city. The results obtained in the questionnaires from the students finances course were compared with the results from the students in the first module of the management technical course. However in the management class the content was developed by exposing the theory and solving problem situations. The guiding question for our research was: “Does a practical approach to the study of financing systems help the student by comparing the methods of payment opt for the most economical option?” The analysis of the results presented a favorable framework for the proposal of a practical approach, prioritizing the use of everyday situations, to the study of payment methods besides it offered a more critical learning to the detriment of a reproductive bias normally observed in the teaching of financial mathematics.
Transformação e permanência : regionalismo e representação da mulher em Faca, de Ronaldo Correia de Brito
(Universidade Federal de São Carlos, 2017-05-10)
Santos, Élide Mendonça dos
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Pellegrini, Tânia
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https://lattes.cnpq.br/0280434883580627
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https://lattes.cnpq.br/1860491964988052
This work aims the investigation of the permanence of a contemporary Brazilian regionalism tradition, based on some tales of the book Faca, published in 2003 by the cearense writer Ronaldo Correia de Brito. These tales are: “A espera da volante”, “Faca”, “Redemoinho”, “A escolha”, “Mentira de Amor” e “Cícera Candoia”. It is proposed to line a possible trajectory for a women’s representation in different kinds of regionalism that comes out in different moments in our literary panorama, basing on canonical works about this subject. Our own work is also based on the critical theory studies to comprovate our hypotheses and objectives. Our choice for this work is justified by the fact that the feminine characters, established in the author’s universe, revisit and reiterate some tradicional codes about genre, but also include new codes that are related with the present time. It reaffirms, in this way, the own survival of the recent regionalism, once that the characters assumed contravention roles, different from that is verified in ulterior phases, engendering the turn of the XIX century. Besides, our hypothesis is the effect of transgression, subversion and punishment, always present in stories and characters in the regionalism expression; it has coming a bit of consuming in the contemporary, to indict, in a certain way, the sociocultural transformations lived in our time.
Mecanismos linguísticos e relações intersubjetivas na produção de textos : atividades enunciativas na prática de ensino
(Universidade Federal de São Carlos, 2017-05-11)
Barros, Solange Christiane Gonzalez
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Valentim, Helena Topa
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Onofre, Marilia Blundi
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https://lattes.cnpq.br/4908382415301882
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https://lattes.cnpq.br/3171777102805120
In this study called Linguistic mechanisms and intersubjective relations in textual production: enunciative activities in the teaching practice, the aim is to recall questions from the Master’s degree, such as the difficulty that students have to insert notions of qualification as explicit marks of intersubjective regulation (commented world) in their textual productions. Analysing, now, a practical work to be done in school contexts and considering the difficulties observed in the students’ textual production, we have the objective to i. explore more deeply the process of constitution of enunciative plans which involve linguistic mechanisms as marks of intersubjective regulation, especially the appreciative modality, which marks the enunciator’s point of view – favourable or unfavourable – about a content that is constructed linguistically; ii. determine and analyse the use of the appreciative modality in a corpus constituted of narrative texts, especially fables; iii. propose linguistic practices to be applied in the exercise of textual production aiming to explore, in the language teaching, the language process which can promote the students’ linguistic-cognitive development. It is used in this work the Theory of Predicative and Enunciative Operations proposed by the French linguist Antoine Culioli.
Seletividade de herbicidas aplicados em pré-emergência e pós-emergência sobre Crotalaria ochroleuca, Cajanus cajan e Raphanus sativus
(Universidade Federal de São Carlos, 2017-05-12)
Pereira, Laís Molinari
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Monquero, Patricia Andrea
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https://lattes.cnpq.br/2766526793830455
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https://lattes.cnpq.br/9612469769486531
Green manure has been widely diffused because of the benefits it brings to the chemical, physical and biological characteristics of the soil. However, the adoption of this practice by farmers depends on the definition of management strategies that allow the full development of these crops in the field. Among the strategies, the definition of selective herbicides is a fundamental point in helping the development of the crop. The objective of this work was to evaluate in the greenhouse if pre-emergence and post emergence herbicides are selective for the three green manure species: forage turnip (Raphanus sativus L. cv. CATI AL 1000), dwarf pigeon pea (Cajanus Cajan (L) Millsp cv. IAPAR 43) and crotalaria (Crotalaria ochroleuca L. comun cv.). In the field evaluate if the herbicides defined as selective in greenhouse will damage crops, in relation to phytomass production. The herbicides applied in greenhouses in pre-emergence were atrazine, saflufenacil, sulfentrazone and metribuzin. Separately, post-emergence bentazon, fluazifop-p-butyl, fomesafem, chlorimuron ethyl, mesotrione, imazethapyr, nicosulfuron, clomazone and imazapique. The doses were 0.5, 0.75, 1 and 1.25 of the commercial dose. The three species of green manure were planted in cups with a capacity of 0.5 L. The application of pre-emergence herbicides was performed one day after sowing, and the post-emergence herbicides were applied when the plants had 2 to 3 Pairs of definitive leaves. Phytotoxicity evaluations were performed at 7, 14, 21 and 28 days post-emergence (DAE) for pre-emergent herbicides and 7, 14, 21 and 28 days after application (DAA) for post-emergence herbicides. At 28 DAE / DAA the aerial part of the plants were collected to determine the dry biomass. In greenhouse the herbicides considered selective for Cajanus cajan were fluazifop-p-butyl, bentazon, imazethapyr, clomazone, imazapique, mesotrione and nicosulfuron. For Crotalaria ochroleuca: fluazifop-p-butyl, imazethapyr, bentazon, clomazone, fomesafem and mesotrione. No herbicide was selective for Raphanus sativus. In the field experiment were used the herbicides that were selective in the greenhouse, in the case only for the crotalaria and dwarf pigeon pea. The experimental design was a randomized block design with 4 replicates for treatments and controls. When the crotalaria plants were with up to 3 pairs of true leaves were sprayed with the herbicides bentazon, fluazifopp-butyl, fomesafem, mesotrione, clomazone and imazethapyr. The application in pigeon pea occurred at the same phenological stage with the herbicides bentazon, fluazifop-p-butyl, mesotrione, imazethapyr, nicosulfuron, clomazone and imazapique. Phytotoxicity of the crops was evaluated weekly until flowering corresponding to 42 DAA for pigeon pea and 56 DAA for sunflower. In the field only the mesotrione in the crotalaria crop caused 100% of phytotoxicity, in the other treatments all herbicides selected in greenhouse were also selective in the field, allowing the complete cycle of the crop and producing significant biomass
Práticas de Produção Mais Limpa e sua relação com o desempenho financeiro das empresas de manufatura listadas na BM&FBOVESPA
(Universidade Federal de São Carlos, 2017-05-12)
Silva, Thiago Lopes da
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Mergulhão, Ricardo Coser
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https://lattes.cnpq.br/0598720328915137
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https://lattes.cnpq.br/2516968651757684
Sustainable development raises at present days a number of challenges to manufacturing, precisely in order to make production more sustainable, equating economic and financial issues with environmental and social issues. Cleaner Production represents one of the approaches which can be used by manufacturing companies in the attempt to achieve this purpose, rightfully represent this a strategy oriented to the reduction of negative impacts arising from production processes in all its extension. As a direct result of the implementation of cleaner production practices, enhances the efficiency of the production process, thus increasing competitiveness of enterprises, whether in terms of increases in manufacturing capacity, both in terms of better prospects of generating financial results. However, in the case of the Brazilian context, are relatively sparse theoretical-empirical evidence that greater intensity as the implementation of cleaner production practices on the part of corporations effectively shown able to influence your financial performance. Under such circumstances, the objective of the present study is to assess whether the greater or less intensity about the implementation of cleaner production practices by manufacturing companies listed on the BM&FBOVESPA shown effectively able to provide significant differences in terms of financial performance. To this end, a survey research was undertaken by the manufacturing companies listed on the BM&FBOVESPA, whose research instrument was constituted in the questionnaire. The collected data were subjected to statistical analysis by means of appropriate software to such purpose, by use of Multivariate Statistical technique called multiple Linear Regression. Finally, the survey results point to the perception that some of the cleaner production practices seem to influence corporate financial performance, profitability, and profitability, than be seen to be viable your implementation under the economic-financial point of view.
Newsminer: um sistema de data warehouse baseado em texto de notícias
(Universidade Federal de São Carlos, 2017-05-12)
Nogueira, Rodrigo Ramos
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Gonzalez, Sahudy Montenegro
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https://lattes.cnpq.br/9826346918182685
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https://lattes.cnpq.br/0327974399448757
Data and text mining applications managing Web data have been the subject of recent research. In every case, data mining tasks need to work on clean, consistent, and integrated data for obtaining the best results. Thus, Data Warehouse environments are a valuable source of clean, integrated data for data mining applications. Data Warehouse technology has evolved to retrieve and process data from the Web. In particular, news websites are rich sources that can compose a linguistic corpus. By inserting corpus into a Data Warehousing environment, applications can take advantage of the flexibility that a multidimensional model and OLAP operations provide. Among the benefits are the navigation through the data, the selection of the part of the data considered relevant, data analysis at different levels of abstraction, and aggregation, disaggregation, rotation and filtering over any set of data. This paper presents Newsminer, a data warehouse environment, which provides a consistent and clean set of texts in the form of a multidimensional corpus for consumption by external applications and users. The proposal includes an architecture that integrates the gathering of news in real time, a semantic enrichment module as part of the ETL stage, which adds semantic properties to the data such as news category and POS-tagging annotation and the access to data cubes for consumption by applications and users. Two experiments were performed. The first experiment selects the best news classifier for the semantic enrichment module. The statistical analysis of the results indicated that the Perceptron classifier achieved the best results of F-measure, with a good result of computational time. The second experiment collected data to evaluate real-time news preprocessing. For the data set collected, the results indicated that it is possible to achieve online processing time.
Avaliação dos efeitos antitumorais do complexo de rutênio [Ru(GA)(dppe)2]PF6 em células não-tumorais e tumorais de mama cultivadas in vitro
(Universidade Federal de São Carlos, 2017-05-12)
Naves, Marina Araújo
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Cominetti, Márcia Regina
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https://lattes.cnpq.br/3725318894555272
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https://lattes.cnpq.br/6398544243407478
Cancers have become an increasingly relevant problem of public health in the last decades. Within neoplastic diseases, breast cancer is one of the most incidental in female population and related to a high mortality rate. Within types of breast cancer, triple-negative is the most aggressive one and prone to form metastasis to lung and brain. Because they do not express hormone receptors, triple-negative tumors do not have an auxiliary target therapy, thus, treatment is hampered and chemotherapy is the only option of treatment remaining for metastatic cases of this tumor type. However, chemotherapy drugs currently used, in some cases are not selective to tumor cells, acting only on the proportion of cells exposed to treatment or cells that are at certain stages of the cell cycle. Thus, non-tumor cells are affected and some neoplastic cells remain intact, characterizing tumor recurrences and resistance to treatment. Rosenberg and colleagues, in 1964, were responsible for the discovery of cisplatin, a metal and antiproliferative compound still widely used in therapies against various types of tumors, but despite its effectiveness, it has several side effects. Therefore, the search for more selective antitumor drugs for neoplastic cells and with fewer adverse effects is critical to advances in the treatment of cancer. With the limitations of cisplatin, new researches have been developed with ruthenium complexes. Ruthenium has properties that may justify its antitumor potential and selectivity for tumor cells; within them, the ability to imitate iron binding to many biomolecules, including transferrin and albumin. Previous studies have suggested the antitumor effects of ruthenium both in vitro and in vivo. Therefore, the aim of this study was to evaluate the chemosensitizing ability of the ruthenium complex [Ru(GA)(dppe)2]PF6, which we called Ru(GA), as well as its antitumor activity on triple-negative breast cancer cells (TNBC). In addition, differences between the in vitro behavior of cells treated with the compound and untreated cells were verified, as well as differences between the activity on tumor and non-tumor cells used in this study. The results demonstrated that the complex Ru(GA) was more efficient in inhibiting the proliferation of triple negative breast cancer cells MDA-MB-231, compared with the non-tumor cell line MCF-10A, which was more resistant to the complex. Furthermore, the compound was able to reduce the number and size of colonies, to modify the cytoskeleton and act inhibiting the migration ability of tumor cells. The complex also induced apoptosis by increasing the expression of pro-apoptotic genes such as Bax, Caspase-9, Caspase-3 and decreasing anti-apoptotic genes Bcl-2 in TNBC cells. Moreover, Ru(GA) was able to increase the expression of apoptotic proteins and sub-G1 phase distribution on tumor cells. Interaction assays with Ru(GA) and transferrin showed that this protein has a strong participation in the contact between ruthenium complexes and tumor cells, increasing their effectiveness. These results show that the complex Ru(GA) has antitumor potential against breast tumor cells and it might be a good alternative drug for the treatment of cancer.
Participação de pequenos grupos neurais seletivamente ativados do córtex pré-límbico na reinstalação da autoadministração de etanol induzida pelo contexto
(Universidade Federal de São Carlos, 2017-05-12)
Palombo, Paola
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Cruz, Fábio Cardoso
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https://lattes.cnpq.br/4804337113083801
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Planeta, Cleopatra da Silva
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https://lattes.cnpq.br/2514762545280942
Context-induced reinstatement of drug seeking is an animal model for assessing the neural mechanisms underlying context-induced drug relapse, a major factor in human drug addiction. Neural activity in prelimbic cortex has been implicated in context-induced reinstatement drug seeking. Here, we report a new and feasible training procedure for context-induced reinstatement of alcohol seeking to explore the role of prelimbic cortex in context-induced relapse to alcohol seeking. Long-Evans rats were first given home-cage access to 10% ethanol. Using a saccharin fading technique, rats were first trained to self-administer 10% ethanol in one context. Next, lever pressing in the presence of the discrete cue was extinguished in a different context. Subsequently, context-induced reinstatement of drug seeking was assessed by re-exposing rats to the drug-associated or extinction context under extinction conditions. Re-exposure to the alcohol-associated context reinstated alcohol seeking and increased expression of the neural activity marker Fos in the prelimbic prefrontal cortex. The percentage of neural activation in this brain region was 3.4 % in extinction context and 7.7 % in drug associated context. Reversible inactivation of neural activity in prelimbic prefrontal cortex using GABA agonists muscimol and baclofen attenuated context-induced reinstatement. Based on previous findings of the literature that Fos-expressing neurons play a critical role in conditioned drug effects, we assessed whether context-induced reinstatement was associated with molecular alterations selectively induced within context-activated Fos-expressing neurons. We used fluorescence-activated cell sorting to isolate reinstatement-activated Fos-positive neurons from Fos-negative neurons in prelimbic cortex and used quantitative PCR to assess gene expression within these two populations of neurons. Context-induced reinstatement was associated with increased expression of the GABAα5 gene and decrease in the AMPA receptor subunit genes GluR1 and GluR2 in only Fos-positive neurons. Our results demonstrate an important role of prelimbic cortex in context-induced reinstatement of alcohol seeking and that this reinstatement is associated with unique gene alterations in Fos-expressing neurons.
Relacionamento entre estrutura e função muscular periférica, inflamação sistêmica e regulação autonômica na capacidade funcional de adultos obesos com ou sem distúrbios metabólicos
(Universidade Federal de São Carlos, 2017-05-15)
Carvalho, Lívia Pinheiro
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Mendes, Renata Gonçalves
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https://lattes.cnpq.br/9634590922242052
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Silva, Audrey Borghi
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https://lattes.cnpq.br/4855616925791895
Obesity is considered a worldwide epidemic, exerting great impact on cardiometabolic morbidity and mortality. Obese individuals often present poor cardiorespiratory fitness (CRF), altered cardiac autonomic modulation (CAM) and muscle functioning and, therefore a higher risk of developing physical disabilities and life-threatening events later in life. However, a subpopulation, the so-called "metabolically healthy obese," appears to be less likely to develop such impairments because of a more favorable metabolic profile, despite excessive body fat. In this context, we proposed the accomplishment of three observational and cross-sectional studies that could contribute to the comprehension of the global capacity and physiological responses in young adults aged 20 to 45 years when submitted to different exercise tests, including the cardiopulmonary exercise testing (CPX), the gold standard method for evaluating CRF, and field functional tests, which are less costly and interesting because they mimic usual activities of daily living, such as the six-minute step test (6MST) (Study I) an the six-minute walking test (Study II). Thereafter (Studies II and III), we aimed to investigate whether there would be an influence of the metabolic profile, namely the association with Metabolic Syndrome (MetS), insulin resistance (IR) and systemic inflammation, in such clinical outcomes. The first study evaluated a sample composed only of sedentary normal-weight (NW) and obese (OB) women (n=31) to investigate the agreement between cardiorespiratory responses from the 6MST and CPX; to develop a predictive equation from the 6MST to estimate the maximal aerobic capacity (VO2peak in the CPX); and to investigate whether aerobic/functional capacities are related to muscle strength and power (knee extensor peak isokinetic/isometric torque, power and total work). We found that CRF, functional capacity (6MST), relative muscle strength and power were lower in OB than in NW women. We demonstrated that body mass index (BMI), age and performance (up-and-down cycles) in the 6MST explain 83% of maximal VO2peak total variance, and it was possible to elaborate the predictive equation. Moderate to strong correlations were found between CRF, functional capacity (6MST) and muscular strength and power. Study II (n=66) aimed at evaluating cardiorespiratory responses to exercise and CAM (at rest and during the submaximal six-minute walking test [6MWT] and 6MST) by linear and nonlinear indices of heart rate variability (HRV), and their associations with IR and systemic in NW and OB men and women, with or without MetS. We found that cardiorespiratory responses to exercise are affected by obesity per se and do not reflect the influence of MetS in obese patients. However, MetS seems to affect CAM at rest and in response to exercise, since we observed reduced parasympathetic modulation and overall HRV at rest as well as an altered complexity in response to exercise in the OB group with MetS. IR was associated with altered CRF, but not with HRV, and serum levels of IL-10 and TNF-α were associated with HRV. Finally, we demonstrated that the 6MST induces greater cardiovascular stress than the 6MWT, and may be applicable for MAC evaluation in clinical practice. Study III (n=61) aimed to compare the metabolic and inflammatory profile, especially the role of specific biomarkers (leptin, LP, adiponectin, ADP and myostatin, MSTN) and muscle function, energy expenditure and CRF between the same groups. The last group, however, was characterized by the association of MetS with IR. We concluded from this study that high levels of MSTN and LP-to-ADP ratio are associated with MetS and IR, low-grade chronic inflammation and low muscle mass. LP/ADP is associated with parameters of obesity alone and with CRF, and neither LP/ADP nor MSTN are associated with energy expenditure and muscle function, as suggested in previous studies in animal models.
A construção de conceitos sobre a pequenez humana : astronomia em aulas de filosofia no ensino médio
(Universidade Federal de São Carlos, 2017-05-16)
Nascimento, Carlos Alexandre do
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Bretones, Paulo Sérgio
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https://lattes.cnpq.br/0016646045895716
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https://lattes.cnpq.br/3524998299814162
This work analyzes the possibility that some of the contents of Astronomy would be introduced in Philosophy classes, verifying its applicability as a proposal for an interdisciplinary activity in high school. The aim of the project was to promote reflection and the creation of concepts with students about their own existence, the human condition on Earth and in the Cosmos. For this, a project was applied in seven classes for a first year high school group of the state school network, at the Francisco Gomes School, municipality of Cravinhos, state of São Paulo. The data was obtained through questionnaires, verbal and written reports and notes of the researcher. The acquisition of knowledge by students both in Astronomy and Philosophy contents is presented, as well as the analysis of this path, seeking the validation of the proposal, being the researcher the teacher of the class itself. The possible tangibility of Astronomy was a starting point to culminate in the inquiries and contents of Philosophy. It was found that both areas make it possible to think about the human condition, its smallness and other aspects related to the human being. In this way, it was verified that interdisciplinarity is possible, between the two convergent areas. A proposal of work in this way can become more attractive to the students, fostering the creation of concepts on the subject of the human being.
Estratégias de marketing de serviços B2B: estudo multicaso em empresas fabricantes de máquinas e equipamentos
(Universidade Federal de São Carlos, 2017-05-17)
Ribeiro, Ricardo Veloso
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Piato, Éderson Luiz
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https://lattes.cnpq.br/1439984077907071
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https://lattes.cnpq.br/0104274974337881
Machine manufacturers and operations between the integrated solut ions of products and services that meet the needs of customers. This sector is important for national sustainable economic development. However, there is little academic research on the strategy and management of services performed by these companies, as h ighlighted in the bibliometric analysis performed in the present study. Thus, a gift aims to identify and analys e how B2B services marketing strategy executed by companies manufacturing machines and equipment and alignment with a customer expectation. The Research was developed with 4 multinational companies, leaders in the segment in which they operate, and 9 client companies, with a total participation of 29 professionals that work in the areas of marketing, sales, projects, technical technique, HR, maint enance and production. The research has a qualitative approach and is developed throu gh multiple case studies, analys ing in the field, as a service marketing strategy from the perspective of the machine and equipment manufacturers and from the customer per spective, based on a literature review on Service M arketing And industrial marketing. As a result, a conceptual framework is presented which shows that the relationship can be affected by several elements of service marketing, such as product, distribution , people and price. However, the price of technical service does not affect the relationship, but the price of spare parts has been highlighted by some customers, such as motivation to look for another supplier. It is noted that it is industrial marketing as trust and commitment are also affected by other elements of marketing services such as communication, productivity and quality.
Seleção de fornecedores sustentáveis utilizando Fuzzy DEMATEL-ANP
(Universidade Federal de São Carlos, 2017-05-18)
Rodrigues, Letícia Reis
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Ganga, Gilberto Miller Devós
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https://lattes.cnpq.br/9062191157466610
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https://lattes.cnpq.br/3334632821347924
The issue of sustainability, which is an increasingly important consideration in the day-to-day operations of businesses, needs to be addressed in the context of supplier selection. The use of multi-criteria approaches in decisions concerning the selection of sustainable suppliers can be a valuable approach for helping to resolve the complexity of this process. A systematic review of the literature highlighted gaps in the research in this area, such as the lack of a detailed description of multi-criteria methods, as well as a scarcity of sustainability criteria that take into account the three main perspectives (Economic, Environmental, and Social). This work describes the development and real case application of a DEMATEL (Decision-Making Trial and Evaluation Laboratory) and ANP (Analytic Network Process) fuzzy modeling technique for the selection of sustainable suppliers. The methodological approach used in the research was quantitative, descriptive, and empirical. The modeling and simulations were performed using MATLAB®. Incorporation of the specificities of the process of selection of sustainable suppliers makes the model a useful tool for use by both businesses and researchers concerned with the issue of sustainability. A systematic review of the published research highlights the main state-of-art methods and criteria used for the selection of green and sustainable suppliers. The model is described in a framework highlighting each step of the application. It was subsequently applied by a major glass packaging company, where the supply chain coordinator agreed to assist in the research. The outputs of the second phase of the model showed that the Economic cluster was most important and interacted with the Environmental cluster, while the Social cluster remained practically inert, without interactions with the other clusters. For the three perspectives, the three most influential criteria were as follows: cost, compliance, and quality (Economic perspective); environmental certifications/ISO 14001, reuse/recovery, and pollution control (Environmental perspective); and stakeholder rights, respect for policies, and encouragement of the development of self-sustainable recycling programs (Social perspective). Finally, a supplier was selected using the framework presented, and the criteria that most influenced the decision were highlighted. The procedure developed here offers a tool to assist businesses searching for sustainable solutions, as well as researchers in the scientific community concerned with the development of knowledge in this area.
Das fórmulas e/ou pequenas frases às aforizações em política: questões teórico-analíticas sobre o “Volta, Lula!”
(Universidade Federal de São Carlos, 2017-05-18)
Conti, Tamires Cristina Bonani
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Baronas, Roberto Leiser
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https://lattes.cnpq.br/4613001301744682
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https://lattes.cnpq.br/3442362906177938
La emergencia de la frase-acontecimiento “Vuelve, Lula!” se dio de manera institucional por declaraciones de Marta Suplicy en el 28 de abril de 2014 por medio del pronunciamiento del líder del Partido de la República (PR-MG) en la Cámara de Diputados, Santana de Vasconcellos (MG). En ese día, el diputado del PR anunció el apoyo de 20 de los 32 diputados de su sigla a la sustitución de Dilma por Lula en la carrera presidencial. En una rápida búsqueda en el sitio de búsquedas Google es posible constar que el enunciado “Vuelve, Lula!” se produce casi cien mil veces. Este enunciado, desde su irrupción, pasó a estar presente en los más variados tipos de texto y en la "boca" de los más diferentes enunciadores, que se inscriben en distintos posicionamientos discursivos. Una vista de los ojos en la literatura pertinente sobre las pequeñas frases en la política nos muestra que esta temática, aunque bastante relevante tanto para los estudios de la ciencia política y de la comunicación como para las ciencias del lenguaje, todavía fue poco tratada, sobre todo en el espacio académico brasileño. Nuestra preocupación inicial en esta investigación fue comprender lo que hace del “Vuelve, Lula!” una especie de pandemia discursiva (verbal e icónica) con casi cien mil ocurrencias. En concreto, en esta investigación, sobre la base de los trabajos de Krieg-Planque (2003, 2008, 2010 y 2012) sobre las pequeñas frases, de Maingueneau (2015), sobre la teoría de las “frases sin texto”, y de Moirand (2007, 2012), sobre las mots-événements, buscamos comprender las propiedades lingüístico-discursivas del enunciado de pequeña extensión “Vuelve, Lula!”, así como de algunas de sus variantes icónicas como “¡Vuelve, Lula! ¡Alguien necesita defender su largado, es decir, su legado! Le-ga-do”. Además, buscamos describir, por un lado, los cotextos y los contextos por los cuales ese enunciado y algunas de sus variantes icónicas circulan en el espacio mediático digital brasileño, más detalladamente en los periódicos Folha de S. Paulo y Estado de São Paulo y en algunos sitios especializados en política – entre los meses de marzo a diciembre de 2014 – período (pre) electoral – y, por otro, las razones coyunturales (políticas, sociales, históricas) que han posibilitado la emergencia de tal enunciado. En conclusión, dada la circulación de esta pequeña frase, en su modo primordial y variantes, entendemos que ella debe ser comprendida como una frase acontecimiento, que produce diferentes tipos de “acontecimientos morales” en la política brasileña.
Ferramentas quimiométricas aplicadas na avaliação de estratégias que visam a remoção de íons fluoreto em efluente de drenagem ácida de mina
(Universidade Federal de São Carlos, 2017-05-19)
Rodrigues, Fabio William
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Pereira Filho, Edenir Rodrigues
;
https://lattes.cnpq.br/3394181280355442
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https://lattes.cnpq.br/8761227302227960
The goal of this study is to provide improvements in the treatment of effluents from acid rock drainage (ARD) of the Mineral Treatment Unit (Caldas / MG) of the Nuclear Industries of Brazil (INB). Due to the presence of fluoride ions in the effluent, the costs of inputs and waste management are in the order of millions of reais per year. Thus, the search for alternative solutions or an optimized condition is of paramount importance, making the current treatment system more efficient from a financial, environmental and social point of view. Of the nine materials initially tested for fluoride removal, five were selected because of the best performance: gypsum, manganese dioxide, alumina, aluminum sulfate and aluminum polychloride. Following, a selection of variables that influence the removal of fluoride was done considering: Dosage of Hydrated Lime; Stage of Addition; Time and Material Dosage, by means of fractional factorial design for each material (5 x 23-1 ). Then, with the variables and materials selected, the work was directed to obtain a response surface that allowed identifying the optimum working region, considering the responses: final fluoride concentration, costs and mass generation of solids. For this, Doehlert type design was used with three variables (13 experiments + 3 replicates) and the evaluated responses were transformed, according to criteria, through desirability function. After obtaining the response surfaces and after the models validation for the best performance materials: gypsum and hydrated lime, the efficiency of the use of gypsum - solid effluent from the treatment of ARD - was tested on continuous scale by a pilot plant operation. It was concluded that the addition of gypsum in two different points in the treatment reached the objective of fluoride concentration (less than 10.0 mg / L) with lower cost of inputs. The proposal allows cost reduction in the order of hundreds of thousands of reais per year.
Preparação, caracterização e otimização de biocompósitos poliméricos comestíveis reforçados com fibras vegetais
(Universidade Federal de São Carlos, 2017-05-19)
Otoni, Caio Gomide
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Aouada, Márcia Regina de Moura
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https://lattes.cnpq.br/2870655742911951
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Mattoso, Luiz Henrique Capparelli
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https://lattes.cnpq.br/5839043594908917
The ever-growing environmental concern arising from the unrestricted exploitation of fossil raw materials for the massive production of non-biodegradable materials, guided by the rapid increase in the world population as well as in the demand for foodstuffs, encourages research on alternative materials from renewable sources. Herein, edible biocomposites based on peach puree or carrot processing waste (CPW) were produced. Hydroxypropyl methylcellulose (HPMC) and cellulose fibers were added to play ligand and mechanical reinforcement roles, respectively. Previously, the film-forming components were comprehensively studied separately. The effects of HPMC chemical structure were investigated in order to choose a grade – Methocel® E4M – that leads to suitable physical-mechanical performance. Cellulose fibers were miniaturized by high-pressure microfluidization and its dispersion within the HPMC matrix was optimized through a central composite design (CCD). Seven microfluidization cicles were found to be ideal for the mechanical reinforcement of the matrix. Once the behaviors of miniaturized cellulose fibers, peach puree, and CPW in the HPMC matrix were elucidated, ternary mixture designs were carried out to set up correlations among biocomposites’ formulations and their mechanical properties. Optimized formulations were used to produce (i) biodegradable biocomposites featuring suitable physical-mechanical properties for packaging applications – using CPW, HPMC, and cellulose fibers – and (ii) edible bioplastics having unique sensory and nutritional characteristics by means of combining peach puree and HPMC. Finally, the production protocols of both materials were successfully scaled-up towards a pilot scale through a continuous casting approach, being the influence of the processing protocols on materials’ properties investigated.
Análise do uso do pensamento estatístico e de técnicas estatísticas em empresas industriais do Estado de São Paulo
(Universidade Federal de São Carlos, 2017-05-19)
Santos, Heitor Alves dos
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Toledo, José Carlos de
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https://lattes.cnpq.br/9421627326330417
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https://lattes.cnpq.br/3300398608680709
In order to reduce variability and improve the performance of production systems, companies seek to apply improvement programs such as Lean Manufacturing (LM), Total Quality Management (TQM), Six Sigma (SS) , Lean Six Sigma (LSS) and TPM (Total Productive Maintenance), among others. According to Makrymichalos et al. (2005) it is necessary to verify the theoretical foundations that underlie these programs in order to be used more efficiently and consequently the companies achieve acceptable results. To that end, these programs at different levels are based on Statistical Thinking (ST) and Statistical Techniques (STech). This dissertation presents the results of a research survey, with 243 industrial companies from the Sao Paulo State, with the objective of analyzing the level of presence of ST and STech in the improvement programs and the perceived results with their use. A group called "Advanced Companies" representing 16.9% of the sample, was identified in the statistical analysis, the companies in this group are the most grounded in the use of ST and STech. In addition, 29.26% of them were able to obtain perceived operational results, 26.82% obtained subjective benefits perceived with the application of ST and STech principles and 17.07% obtained both perceived operational results and subjective benefits with the use of ST and STech. The companies in this group obtained these results mainly due to the use of SS and LSS for more than 5 years. These programs incorporate the ST principles more intensively and use the basic, intermediate and especially advanced STechs.
Dinâmica do uso da terra e naturalidade do entorno da Floresta Nacional de Irati
(Universidade Federal de São Carlos, 2017-05-19)
Almeida, Dayana
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Bogaert, Jan
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Santos, José Eduardo dos
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https://lattes.cnpq.br/8533387365058570
;
https://lattes.cnpq.br/8099346855929913
Protected areas are an important strategy for the maintenance of biodiversity. However, land use dynamics of the protected areas buffer zones receive little attention in literature. The goal of this research was to identify the landscape constraints and modelers in order to maintain the naturalness of the scenarios surrounding Irati National Forest, based on the temporal and spatial dynamics of the land use and cover analysis and the Distance to Nature Index (D2N) application for the period from 1986 to 2016. The land use and cover dynamics for the study area was obtained by on-screen digitizing of LandSat-5 and LandSat-8 imagery for 1986, 1997, 2011, and 2016 in ArcGis 10.2 software, using the hemeroby scale. A trajectorie analises between the years 1986-1997, 1997-2011, 2011-2016, 1986-2016, and 1986-2016 were used to evaluate the landscape dynamics. The D2N index was applied to measure the anthropogenic impact on biodiversity based on the dynamics of land use and cover of the study area for the four years. To test the null hypothesis of the D2N index between 1986, 1997, 2011, and 2016, a multivariate permutation analysis with Euclidean distance was performed. There was an increase of the anthropisation in the surrounding Irati National Forest. However, the region still presents an expressive degree of naturalness, mainly when compared to others surrounding protected areas. The changes in the landscape presented a different dynamic regarding the different agricultural production systems in the study area. In this way, as the maintenance practices of Irati National Forest natural condition and its surroundings will also present different profiles of each production system. The statistical analysis of the D2N results shows that only 1997 presented a statistically significant difference. The results demonstrate that D2N can be an effective tool for monitoring and planning to identify a natural condition and areas with greater anthropogenic influence, proposing scenarios for biodiversity conservation.
Aluno com altas habilidades/superdotação: um estudo longitudinal a partir da teoria das inteligências múltiplas
(Universidade Federal de São Carlos, 2017-05-23)
Marques, Danitiele Maria Calazans
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Costa, Maria da Piedade Resende da
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https://lattes.cnpq.br/2791098416503955
;
https://lattes.cnpq.br/0940222268032312
The process of recognition, identification and attendance to the student with High Abilities is something still seen by the school system in a very complex way, full of barriers and exclusion to the most capable student. Given this reality, this thesis presents a general objective of longitudinal analysis of the process of recognition, identification and attendance of a student with indicators of High Abilities/Giftedness in the multifaceted view of Multiple Intelligences. Specific objectives include: (i) to explorer and evaluating student identification procedures in the precocity phase; (ii) to develop and describe a procedure for identifying and assisting students with High Abilities/Giftedness in the multifunctional resource room; (iii) to organize strategies that facilitate the pedagogical practice of the Special Education teacher in the care of the student with High Abilities/Giftedness; (iv) investigate the teacher's conception of the regular classroom in having a student with High Abilities/Giftedness; (v) to analyze the conception of the Special Education teacher in relation to the attendance of the student with High Abilities/Giftedness in the multifunctional resource room; (vi) to investigate the consequences of the process of acceleration in the trajectory of the student; (vii)to analyze the conception of the parents in relation to the academic trajectory of the student. The research took place from 2012 to 2016, during which time the student from five to nine years old was accompanied. This study was based on the Longitudinal Non-Experimental Survey, with case study delineation. Participants included a student, his parents, his teacher of Early Childhood Education, his teacher of the 2nd year of Elementary School and his teacher of Special Education. For data collection, interviews, questionnaires and questionnaires were used. The Research had as theoretical foundation the Theory of Multiple Intelligences. The data analyzes were carried out from a screening of student identification with high skills/gifted indicators and from interviews to ascertain the parents 'and teachers' conceptions about the student with High Abilities/Giftedness. As results, at five years of age, the student presented indicators of precocity. These characteristics were continuous and frequent; thus, it was concluded that the manifestation of precocity was one of the indicators for the identification of high skills/giftedness of the student. The process of acceleration according to the conception of parents and the teacher of Special Education occurred in a positive way, providing the student with motivation and enthusiasm to attend school. The Specialized Educational Attendance held in the multifunctional resource room occurred from 2012 to 2016, as a form of enrichment. From the evaluation triage the student was identified as a student with High Abilities/Academic giftedness, above average capacity in the areas of Language (oral and written), Mathematics, Space, Science and Technology.