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Avaliação comportamental de camundongos expostos ao teste de aversão condicionada ao contexto induzida pela interação social agressiva
(Universidade Federal de São Carlos, 2018-09-18)
Penagos Gil, Jeimmy Marion
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Souza, Ricardo Luiz Nunes de
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https://lattes.cnpq.br/2475842684688693
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https://lattes.cnpq.br/1550425716406903
Rodents exposed to social defeat stress exhibit hormonal, behavioral, and autonomic responses called defense reactions. This study sought to conduct a behavioral validation of a context aversion generated by social defeat test. Ninety-eight male albino Swiss mice were habituated for 10 minutes for three consecutive days to an apparatus, containing a tunnel-bound burrow, which leads to a surface (divided by a wire mesh) that has two parts of the same dimensions : Surfaces A (site of social interactions with physical contact) and surface B (location of social interactions without physical contact). The burrow, the tunnel and the surface A are separated from each other by guillotine doors. From the 4th to the 7th day, the animals were distributed in: (a) control group (animals exposed to social interaction with non-aggressive conspecific), (b) defeated group (animals exposed to social interaction with a dominant conspecific), exposed to 5 minutes of sensory interaction. In this interaction an aggressor or non-aggressor mouse was placed on surface B separated from the other animal by the wire mesh, followed by social defeat or non-aggressive interaction on surface A for 3 minutes. Subsequently, aggressive or non-aggressive animals were placed on surface B for a further 5 minutes, to the adapted test of interaction with the conspecific (same context where they were habituated). Following the same protocol, but in a new context (social interaction box), group (c) control - new context was exposed to social interaction with a non - aggressive cospecific, and group (d) defeated - new context was exposed to interaction with a dominant co-specific. On the eighth day, all animals were individually exposed to the Adapted test of interaction with the conspecific for 10 minutes, without the presence of the coespecific, but containing a portion of the sawdust of their housing cage. On the third day of Habituation and on the Day of Reexposure, the following measures were recorded: frequency of entrances and time spent in the burrow, tunnel and surface A; frequency and time of rising and grooming; SAP total time and time to dig on the surface. When compared to the Hab stage, on the eighth day the GD had a decrease of rising, the permanence time on surface A and excavation of the sawdust, as well as increase in the frequency and time of grooming in the burrow and in the frequency of total SAP stretched. Analysis of the results did not reveal any signs of environmental avoidance in GC, GDn or GCn animals. Our results showed that the use of four social defeats preceded by or followed by sensory exposure to the aggressor opponent causes aversion conditioned to the context of the clash.
Delegacia Eletrônica: uma inovação da polícia civil do estado de São Paulo
(Universidade Federal de São Carlos, 2018-09-18)
Florencio, Patricia Fernandes de Souza
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Fonseca, Sérgio Azevedo
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https://lattes.cnpq.br/2879240108726907
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https://lattes.cnpq.br/1311549900424023
The concept of the Electronic Government (e-gov) leads us to consider that the Information and communication technology (ICTs) are applied at various levels of government, especially the evolution of public services. The entrepreneurial State appropriates the theories of innovation and is a fundamental player in the development of society. The search for excellence in the provision service led to the creation of the Electronic Police Station by the Civil Police of the State of São Paulo. Seeking to contribute with the innovation studies in the public management. This work identifies solutions adopted to overcome of difficulties encountered in the implementation of this pioneer project in the State of São Paulo to serve as a reference for future developments, provide context within the models of public management, and address innovation paradigms. Through of qualitative research of exploratory character, the single case study was used by interviews and access to several documents. As a result, after the content analysis, we have the presentation typification of the object under the light of innovation, relating it with the management models and demonstrating the way of overcoming the barriers encountered.
Vozes do sucesso: uma análise dos discursos sobre os vícios e virtudes da voz na mídia brasileira contemporânea
(Universidade Federal de São Carlos, 2018-09-18)
Soares, Thiago Barbosa
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Piovezani Filho, Carlos Félix
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https://lattes.cnpq.br/1677609008094603
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https://lattes.cnpq.br/8919327601287308
This paper analyzes discourses about what can be called the voices of success produced and / or conveyed by the great contemporary Brazilian media. More precisely, we describe and interpret the process of meaning production in statements made and formulated by Brazilian media discourses that manifestly deal with the voice of subjects whose success stems from their vocal performance, especially in the context of music. Thus, when we consider the postulate of the Discourse Analysis formulated by Pêcheux (2009) that subject and meaning are at the same time constituted in the historical movement, we understand that the words about the voice of success produce, at the same time, the senses and the subjects inside. Before this picture, we investigate what is said and how the voice is stated in the discourse of success in the current Brazilian society and the differences in the treatment of the voice of those who figure in the media world. Specifically, we aim to understand what distinctions may exist in terms of the production of meanings of the voices of success when disseminated by specialized or traditional, conservative or progressive vehicles of medium and large circulation. To do so, we analyzed a corpus consisting of texts from Rolling Stone, Billboard, Carta Capital e Veja and the Folha de São Paulo and O Estado de S. Paulo newspapers, published between January 2010 and December 2015. From this, we verified which is said of the voice, especially in the mainstream media, in order to reproduce inequalities and support various effects of sense of success in texts with massive circulation. In view of this, we find that there is a silencing of stigmatized voices within the media universe and, as one of its repercussions, there is a symbolic constellation in the collective imaginary, on which the reproduction of the statements of the voices of media success weighs. We observe the existence of a vocal aesthetic whose origin is at the junction of the cultural entertainment industry with the mainstream media, aiming at the dissemination of the voices of success. The methodological procedures adopted in the development of this study are based on qualitative research, in the realization of which we seek to identify regularities / irregularities, continuities and discontinuities of linguistic-discursive units of utterances within relatively distinct ideological orientations concerning speeches about subjects' voices of media success.
A motivação de alunos na preparação e demonstração de experimentos para a divulgação de química: um olhar a partir da teoria da autodeterminação
(Universidade Federal de São Carlos, 2018-09-19)
Faitanini, Beatriz Derisso
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Bretones, Paulo Sérgio
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https://lattes.cnpq.br/0016646045895716
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https://lattes.cnpq.br/4716307148937666
This research had as its main objective the study of the motivational profile of students from the first year of High School in a private school of São Carlos during the completion of a choice process, preparation and demonstration of experimental practices of Chemistry. For understanding of the motivation in the school context it was used as a theoretical reference the Self-Determination Theory, outlining six motivational levels which an individual may present, proposing a self-determination continuum of self-determination. To collect data two questionnaires were used, an open-ended and the other using the Likert scale, applied before and after the completion of a process, and the meetings filming. The open-ended questionnaire aimed to evaluate the satisfaction of the basic psychological needs of the students during the research; the questionnaire using the Likert scale aimed to obtain the students' motivational profile. The data analysis showed that before the implementation of this project the students had higher MR values for the Integrated Regulation and lower for the less self-determined motivational forms. After the project was carried out, the MR values for Integrated Regulation and Intrinsic Motivation increased even more, while the values for less self-determined forms, such as amotivation, decreased, showing that there were – in reference of learning motives - a significant variation in the students' motivational profile. The individual analysis of the students showed that there was a significant change in the motivational orientation of three students, while the others remained with the same motivational orientation, mainly because they were students who declared themselves motivated to study Chemistry even before the implementation of the project. We also observed that the data provided elements that confirm that the occurrence of situations that favor the satisfaction of the basic psychological needs brings the enthusiasm of the students in situations considered favorable to the promotion of intrinsic motivation. Thus, the data collection instruments showed themselves as adequate for the objectives of this work, but it is still important to continue research on the motivation of students in chemistry classes, mainly to understand how the satisfaction of basic needs can influence this change of motivational profile and what factors influence the satisfaction of these needs.
Estudo de microscopia eletrônica de transmissão in situ de nanoestrutura de óxidos mistos em altas temperaturas
(Universidade Federal de São Carlos, 2018-09-19)
Maya Johnson, Santiago
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Leite, Edson Roberto
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https://lattes.cnpq.br/1025598529469393
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https://lattes.cnpq.br/1898909730588076
This work addresses the characterization of the high temperature reactions between different nanoparticles oxides, CeO2-ZrO2 and CeO2-SnO2, by the direct observation of the phenomenon by in situ Transmission Electron Microscopy (TEM). The nanoparticles were synthesized via three different synthesis methods, hydrothermal, solvothermal, and solvent-control. The changes in the size and morphology of the nanoparticles, the interactions that lead to processes of sintering / densification, and the phase transformations that occur during the experiments were documented. Also, a detailed study of the influence of the electron beam current density on the sample, and its synergism with the temperature during the in situ experiments was performed. The interactions between the oxide metal nanoparticles and the films of the TEM grids showed a great influence during the in situ tests at high temperature. For the experimental setups tested in this work, the main mechanism of interaction between the nanoparticles was oriented attachment.
Predicting the direction, maximum, minimum and closing price of daily/Intra-daily bitcoin exchange rate using batch and online machine learning techniques
(Universidade Federal de São Carlos, 2018-09-19)
Arguelles, Dennys Christian Mallqui
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Fernandes, Ricardo Augusto Souza
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https://lattes.cnpq.br/0880243208789454
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https://lattes.cnpq.br/6617444730810557
Bitcoin is the most accepted cryptocurrency in the world, which makes it attractive for investors and traders. However, the great challenge in predicting the Bitcoin exchange rate is its high volatility. Therefore, the prediction of its behavior is of great importance for financial markets. In this way, in recent years, Few studies were proposed based on the use of machine learning techniques to predict the direction of their exchange rate, albeit with low precision. Therefore, as a first contribution of this paper, it can be highlighted the analysis and identification of internal and external variables/attributes considered as relevant for predicting the Bitcoin exchange rate in daily and intra-daily time frequencies. The increased use of machine learning techniques to predict time series and the acceptance of cryptocurrencies as financial instruments motivated the present study to seek more accurate predictions for the Bitcoin exchange rate. For this purpose, it was used different techniques of attribute selection to candidate variables. In relation of internal variables is proposed to use Blockchain information and generate technical indicators commonly used by traders. About external variables is proposed to use international economic indices and social trends extracted from Google and Wikipedia. As a second contribution, a methodology is proposed to predict the direction of the Bitcoin exchange rate against the dollar. In addition, it was explored the possibility of directly predict the maximum, minimum and closing prices, including these information to predict the trend. For this, Artificial Neural Networks, Recurrent Neural Networks, Support Vector Machines and Ensemble models (combining regression and clusterization) were used. As a third contribution for intra-daily time frequency, the data-stream learning methods are explored under the hypothesis that Bitcoin price presents a non-stationary behavior. Thus, it is observed that in long term, Bitcoin behaves more like a traditional instrument and, therefore, is increasingly affected by the international context and economic fundamentals. Likewise, the results showed that the selected attributes and the best machine learning model achieved an improvement of more than 10% in accuracy, for the price direction predictions with respect to the state-of-the-art papers, using the same period of information. In relation to the maximum, minimum and closing Bitcoin prices regressions, it was possible to obtain Mean Absolute Percentage Errors between 1% and 2%. Finally, in the prediction of intra-daily price movement, through the use of data-stream learning techniques, is obtained a result that improves more than 6% in accuracy to other previous studies.
Comparação entre o custo de capital aplicado pela ANEEL nas revisões tarifárias e o custo de capital das distribuidoras de energia elétrica para o período de 2015 a 2017
(Universidade Federal de São Carlos, 2018-09-20)
Bueno, Emilene Francisco
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Albuquerque, Andrei Aparecido de
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https://lattes.cnpq.br/9667573506903226
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https://lattes.cnpq.br/8556284258528916
The formation of electric energy tariffs in Brazil involves a series of procedures and regulations, and the regulatory agency (ANEEL) role is to establish and review the methods adopted. One of the methodologies involved in the calculation of tariffs is the remuneration of the capital invested by distribution concessionaires in the sector, obtained through the regulatory capital cost determination (WACC). This cost is calculated during the tariff review processes to which the distributors are subject periodically, and directly influences the index of it repositioning passed on to the consumer, as well as serving as economic parameter for the investments in the sector. Considering the existence of specific aspects of regulatory acts in the calculation used by ANEEL, this work has as a goal to verify if the cost of regulatory capital and the cost of capital of the electric energy distributors, calculated from six different models, are statistically similar or if there is a possible overvaluation or devaluation of the index set by the regulatory agency. Because of the disclosure by ANEEL of two regulatory WACC values, a so-called "before tax" and "after tax", comparisons are made from the two indexes in order to verify their peculiarities. It is used as sample 10 electric power distribution companies from public capital that had their definitive processes of fee revision concluded during the triennium 2015-2017. To verify the hypothesis of this study, we performed analyzes of absolute and relative deviations and non-parametric single-sample tests (Wilcoxon's test). The results indicated that both the "before tax" regulatory WACC and the so-called "after tax" WACC are higher than the average results obtained for the capital cost from 10 distributors, but the first index (which is actually used in the remuneration distributors' capital) shows a greater discrepancy. These two ways of calculation and dissemination of indices "before" and "after tax" by the regulatory agency itself already is a difficulty factor in the process of comparison between the cost of regulatory capital and the calculated using other models. Watching the main objective, this research finds that the regulatory rate of return is generally overestimated by the regulator, that is, the State has provided the investor with a profitability higher than the adequate cost of capital. This causes a greater attractiveness for the investments, but it charges the consumer more by repositioning the tariffs. Finally, considering that ANEEL estimates the WACC for up to 3 years, it can be observed that the method used does not following the oscillations of the Brazilian economic market. This makes both investor or consumer be harmed or benefited, depending on the year analyzed.
A educação profissional técnica de nível médio: visão dos professores sobre um programa especial de formação pedagógica de formação continuada na modalidade EAD
(Universidade Federal de São Carlos, 2018-09-20)
Ferrari Junior, José
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Rink, Juliana
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https://lattes.cnpq.br/5772465855816353
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https://lattes.cnpq.br/7850059028966559
This work was performed with teachers working in the Professional Technical Education (PTE) of two State Technical Schools, located in different municipalities of the interior of the state of São Paulo, and who attended the Special Pedagogical Training Program (SPTP) of-fered by the Paula Souza Center in the distance modality, in the editions of 2014, 2015 or 2016. The objective of this study was investigate and analyze the view that these teachers have on the continuous formation mediated by a Virtual Learning Environment, as well as to discuss the potentialities and weaknesses of a continuous training in the distance modality. Regarding methodological procedures, in addition to documentary analysis, a field research was carried out with thirteen teachers who attended the referred training program. The data collection instrument was a questionnaire structured in four axes: General Profile, General Training, Continuing Education and Specific Training through the Special Pedagogical Train-ing Program. For purposes of data analysis, the discursive textual analysis was use. The results show that approximately 60% of the participants have, on average, 3 to 4 years of teaching experience in the institution and about 2/3 have other work in parallel to the role of teacher. Most stated that they had little or no contact with pedagogical knowledge in the initial for-mation. For 85%, the time factor is the main obstacle to attending a continuous training and more than half claimed the need to take courses according to the training in the technical area. Regarding the teachers' view of the SPTP in the Distance Learning (DL), the most highlighted potential was the possibility of using in their classes the methodological strategies addressed during the course, and the main advantages were flexibility and time management. On the other hand, the disadvantages were the lack of support on the part of the tutor, the evaluation and the impersonal character of a course in the DL modality. In addition, there were reports on the relevance of the knowledge of professional training for application in teaching practice. We expect that this study will contribute to the improvement of Continuing Education Pro-grams for the PTE and the promotion of new research on the subject.
Avaliação do comportamento fluidodinâmico lı́quido-sólido em biorreatores de leito fluidizado utilizando técnicas de fluidodinâmica computacional (CFD)
(Universidade Federal de São Carlos, 2018-09-20)
Koerich, Daniela Maria
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Rosa, Leonardo Machado da
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https://lattes.cnpq.br/8828891443369274
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Lopes, Gabriela Cantarelli
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https://lattes.cnpq.br/5680967191791061
Anthropogenic actions have promoted technological challenges, for example, in the treatment of large quantities of wastewater, which can be done in fluidized bed bioreactors. For the study of these bioreactors, numerical techniques such as computational fluid dynamics (CFD) can be applied. However, in most of the literature available for multiphase systems, there are applications for gas-liquid or gas-solid systems. On the other hand, the dynamics in bioreactors is dominated by interactions between the liquid and solid phases. Thus, the aim of this study is to evaluate the hydrodynamic behavior of a liquid-solid fluidized bed bioreactor using CFD techniques. For the conduction of the simulations, a two-phase, Eulerian-Eulerian, transient and turbulent model was applied in a three-dimensional geometry, using the OpenFOAM code. Valid models have been established for the simulation of systems involving liquid-solid interactions, present in tapered fluidized bed bioreactors. Results showed the effect of the lift force on redistribution of bioparticles. Conversely, the coefficient of restitution did not affect significantly the height of the fluidized bed. The drag force estimate needed to be altered, and a dependency with the particles Reynolds number promoted good agreement of the fluidized bed height with experimental literature data. Using the validated model, it was observed that the study was conducted in the partially fluidized bed regime. None of the cases showed a meaningful presence of “dead zones”. Finally, it was noticed that both collisions between particles and shear stress (parameters that affect the biofilm thickness) occur concomitantly. Thus, greater bed expansion is not directly related to lower incidence of collisions between particles. The intensity of both parameters can be attenuated with the increased angle of the reactor.
Estudos fisiológicos, nutricionais e moleculares de variedades de cana-de-açúcar (Saccharum spp.) sob estresse por alumínio
(Universidade Federal de São Carlos, 2018-09-21)
Oliveira, Mariane de Souza
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Soares, Marcio Roberto
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https://lattes.cnpq.br/6337462438517339
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Fuentes, Andrea Soares da Costa
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https://lattes.cnpq.br/2426157257540389
Sugarcane is a crop of global importance and has been expanding to areas with soils containing high levels of exchangeable aluminum (Al), which is a limiting factor for crop development in acidic soils. The study of the sugarcane physiological and nutritional behavior, together with patterns of gene expression in response to Al stress, may provide a basis for effective strategies to increase crop productivity in acid soils. Sugarcane varieties were evaluated for physiological parameters, nutrient and Al content in leaves and roots and gene expression by qPCR, with the genes MDH, SDH, both related to the production of organic acids, and SOD, related to the oxidative stress. Al affected the varieties behavior in relation to the studied parameters. The RB928064 showed the highest decrease in nutritional content when submitted to Al stress, higher leaf metal content and decreased transpiration rate and stomatal conductance. The variety RB867515 was the most resilient in relation to nutrient content, with little variation between treatments. It presented higher Al content in the roots, and like the RB935744, did not suffer variation in stomatal conductance and transpiration. For the studied genes, in RB928034 occurred greater MDH expression in leaves and SOD in leaves and roots. In RB935744, SDH was more expressed in leaves and MDH and SOD in roots, whereas for RB867515 all genes were more expressed in the roots. The occurrence of distinct Al responses among the varieties may provide different management strategies, seeking to allocate the less susceptible varieties in the places with Al toxicity. The results contribute to the development of Al tolerant sugarcane varieties, aiming the expression of all its genetic potential with the lower demand of inputs.
Transição da criança com deficiência da Educação Infantil para o Ensino Fundamental: uma análise dos processos avaliativos no município de São Carlos-SP
(Universidade Federal de São Carlos, 2018-09-21)
Nascimento, Sandra Regina do
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Tomazzetti, Cleonice Maria
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https://lattes.cnpq.br/4821077407620769
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https://lattes.cnpq.br/9914728971207026
Esta investigación fue desarrollada en la Maestría del programa Pós-Graduación Profesional en Educación de la Universidad Federal de São Carlos. Tuvo por objetivo investigar y comprender como ocurre la transición del niño con deficiencia en la Educación Infantil y su enseñanza fundamental en la red municipal de enseñanza de Sao Carlos-SP y cómo se clasifica la relacion con ese proceso. Se tomo como objetivos específicos: 1. Analizar las orientaciones legales que relacionan la transición y validación entre las etapas de la educación infantil y la educación básica; 2. Identificar y analizar como sucede esta transición para los niños con deficiencia; 3. Indagar la fragilidad de esas prácticas; 4. Analizar como son realizados los procesos de validación en la educación infantil y educación básica en niños con deficiencia, por la profesora del salón de clases, y por fin 5. Analizar los documentos oficiales del ministerio de educación (MEC). Se inclino por algunos conceptos de la teoría histórica-cultural para explicar la protagonización de las fases de desenvolvimiento infantil en esta transición y la importancia de las experiencias vividas en la educación infantil para el desenvolvimiento integral de los niños. Como aporte metodológico, se sustenta el trabajo abordando el método de triangulación, con lo cual, se utilizaron tres procedimientos: revisión bibliográfica, análisis documental y investigación de campo cuyos datos surgieron de encuestas respondidas por profesores (de educación infantil y del primer año de enseñanza básica) y administradores (supervisores y director). También se busco los datos cuantitativos sobre las matriculas de niños con deficiencia en la red municipal de enseñanza de Sao Carlos. La investigación revelo las estrategias de docentes en la educación infantil y de enseñanza básica de acuerdo como sucede el registro de los procesos de desenvolvimiento de los niños con deficiencia en estas dos etapas de enseñanza; y recalcando la importancia de los registros validados y la documentación pedagógica para la continuidad de este proceso en su transición para la enseñanza básica. Como resultado se puede resaltar: el protagonismo de la validación de este proceso; la necesidad de formación inicial y continua de calidad que atiende la demanda de inclusión escolar; de constatar de BOOM en el diagnostico de TGD (trastorno global de desenvolvimiento) ya que , en las primeras etapas de educación infantil; y la escasez de acciones efectivas por parte del poder publico que dan soporte a esta transición, debido al desconocimiento/incumplimiento de algunos documentos mandatorios del MEC en las articulaciones de este proceso.
Equações de evolução com laplaciano fracionário: existência, unicidade, estimativas Lp-Lq, conservação generalizada de energia e espalhamento
(Universidade Federal de São Carlos, 2018-09-21)
Lourenço, Linniker Monteiro
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Ebert, Marcelo Rempel
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https://lattes.cnpq.br/2266906291626715
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https://lattes.cnpq.br/1692257129108144
In this thesis we study some sigma-evolution equations in the Petrowsky's sense. When the coefficients are constant we obtain Lp-Lq estimates for linear equations and apply them to obtain results of existence, uniqueness and Blow-up for a semilinear model. When we have time-dependent coefficients, we obtain Lp-Lq estimates, energy estimates and scattering for linear problems.
O bloqueio dos receptores glicocorticóides da região infralímbica do córtex pré-frontal medial facilita a aquisição, mas não a consolidação da memória de camundongos submetidos ao protocolo de teste e reteste no labirinto em cruz elevado
(Universidade Federal de São Carlos, 2018-09-21)
Fonseca, Aura Julieth Rodriguez
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Souza, Rimenes Rodrigues de
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https://lattes.cnpq.br/6635717840735635
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Souza, Azair Liane Matos do Canto de
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https://lattes.cnpq.br/2352004564367849
A single experience (test) in the elevated plus maze (EPM) increases the avoidance of open arms and impairs the anxiolytic efficacy of the midazolam benzodiazepine agonist (MDZ) in a subsequent re-esposition (retest). Phenomenon known in the literature as "one trial tolerance" (OTT). Studies consider that OTT is due to a memory of the first exposure that allows changes in the strategy adopted at retest or day 2. Glucocorticoid receptors in the infralimbic subregion (IL) of the medial prefrontal cortex (mPFC) have been described as important modulators of learning and cognition; however, their involvement in establishing OTT remains unknown. This study investigated the effects of bilateral injection intra- mPFC -IL of RU486 (glucocorticoid receptor antagonist, GR) in the acquisition and consolidation phases of the memory of mice submitted to the test and retest protocol on the EPM. Experiment 1 (acquisition phase): independent groups of Swiss male mice received either intra-IL bilateral vehicle injection or RU486 (0.3 or 1 ng / 0.1μL) 5 minutes before the test and were exposed to EPM for 5 minutes. Twenty-four hours later, the subjects received vehicle injections or MDZ (2 mg/kg) (i.p), 30 minutes before retest in the EPM. Experiment 2 (consolidation phase): similar to Experiment 1, except that the animals in each group were exposed to the EPM test for 5 minutes, and after received injection intra- mPFC -IL of vehicle or RU486. The analysis of variance (ANOVA) followed by Duncan's post hoc showed that in Experiment 1, prior to the test period, none of the doses of RU486 had an effect on OTT for MDZ, suggesting no effect on the phase of memory acquisition. However, the combined treatment was able to reduce behavioral parameters such as risk assessment (SAP) in the reexposure to EPM. For Experiment 2 after the test period, none of the doses of RU28318 had an effect on OTT for MDZ, suggesting no effect on the memory consolidation phase. These results indicate that RU486 does not play a role on the memory acquisition of a trial 1 in the EPM, however was observed attenuation on anxiety-like behaviors. Additionally, our data indicate that RU486 does not play a role on the memory consolidation of a trial 1 in the EPM. Taken together, the present results demonstrate that the glucocorticoid receptors located within the mPFC -IL are involved in the development of mnemonic aspects related to learning in aversive situations.
Análise do comportamento e planejamento cultural: utopia ou distopia?
(Universidade Federal de São Carlos, 2018-09-24)
Rocha, César Antonio Alves da
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Laurenti, Carolina
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https://lattes.cnpq.br/0100195996020169
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Rose, Julio Cesar Coelho de
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https://lattes.cnpq.br/3386857761295187
The notion of science has undergone continuous transformations throughout history, from the Aristotelian conception of contemplative knowledge to the modern ideal of operative knowledge. The modern perspective on science as knowledge was received with antagonistic expectations in the philosophical sphere. On one hand, what is identified as a Promethean narrative highlights the potentiality of science as a means for the emancipation of humanity and the catalyzing of human progress; on the other, the Faustian narrative represents opposing expectations, alerting to the hazards involved in the employment of science and its by-products to the domain of the natural world. Taken to the extreme, these two tendencies symbolize what, in the literary context, can be identified as the established antithesis between utopia and dystopia. In principle applicable to science in general, this oppositional duality is paralleled in the manner in which the ideas of B. F. Skinner, theoretician of behavioral analysis and proponent of the notion of cultural design, were received. Seen with enthusiasm by some and suspicion by others, Skinner's ideas about the science of behavior in general and the management of life in society in particular have been the subject of controversies still unresolved today. This work aimed at a detailed examination of the affinities of the Skinnerian proposition of cultural planning with the notions of utopia and dystopia, with special attention to possible relations with the second notion, in order to answer the question presented in the title: would cultural design implie utopia or dystopia? As an analytical strategy, the Prometheus-Faustian duality was used as a key to read and examine the Skinnerian text, chapter by chapter, in search of inclinations for each of these tendencies. The path pursuited initially involved an analysis of the Skinnerian view on science, technology and behavioral control; then the target was the theoretical formulation of cultural design; later, it was investigated how the proposition was illustrated by the author in its fictional work, Walden Two; finally, starting from a panorama on the genesis and development of the notions of utopia and dystopia, affinities were probed between the proposal of cultural design and these two notions. The results reveal that it is possible to identify inclinations both to the notion of utopia and to the notion of dystopia, and that the complexity of Skinnerian thought prevents an unequivocal answer to the title question. This result led to a conclusion that proposes a re-reading about the proposal of cultural design that relativizes and conceives it outside the dyad utopia-dystopia. The thesis advanced in this work proposes a parsimonious perspective, which updates the proposition of cultural design in light of contextualist and pluralistic objections, preserving its most auspicious factors, such as the experimentalist attitude, and abandoning its anachronistic traits, such as the technocratic platform. Thus, the proposal of cultural design is conceived as a gradualist effort to test contingency arrangements alternative to those institutional arrangements then in development, focusing on small-scale reforms that prioritize, as far as possible, the controlo of people by people, not as means for radical transformations or the establishment of utopian scenarios.
Mapeamento do processo de nucleação e crescimento do peptídeo beta amilóide pelo complexo luminescente cis-[Ru(phen)2(Apy)2]2+
(Universidade Federal de São Carlos, 2018-09-24)
Cali, Mariana Pigozzi
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Carlos, Rose Maria
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https://lattes.cnpq.br/1589143355309943
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https://lattes.cnpq.br/7379451505839507
Amyloid beta (Ab) is a peptide fragment highly prone to aggregation that deposits in the extracellular medium and is directly associated with the development and progression of a number of nervous system diseases, in particular, Alzheimer's disease (AD). With this in mind, the objective of this work is to obtain a luminescent Ru(II) complex capable of mapping in real time the aggregation process of the amyloid beta peptide through light stimulus. The cis-[Ru(phen)2(Apy)2]2+ complex was synthesized for this purpose. The complex showed an intense and wide absorption band covering the region 350 to 600 nm with a maximum of 450 nm (molar absortivity = 9800 mol-1.L .cm-1) and broad emission with maximum at 655 nm, exhibiting a Stokes shift in the order of 4800 cm-1 and phosphorescence lifetime of 129 ns. The interaction of the complex with the Aβ1-40 peptide was analyzed by the luminescent responses of the complex throughout the course of aggregation. Interaction studies through changes in luminescence intensity were conducted. Luminescent images and changes in luminescence lifetimes during the aggregation process were obtained by confocal microscopy using the FLIM technique (Fluorescence Lifetime Imaging). The complex proved to be a good marker for the Ab peptide aggregation process. With the fluorescence lifetimes obtained from the luminescent images, it was possible to evaluate the interaction between the complex and Ab1-40. Ab1-40 images, with samples being prepared without the complex, have an average bi exponential lifetime of 3.5 ns. On the other hand, the images of the complex Ab1-40 have an average tri exponential lifetime of 4.8 ns, with a significant contribution of a third long lifetime of around 7 ns. Once the interaction between the complex and Ab1-40 was confirmed, the possible sites of interaction were investigated. Three fragments of the peptide were studied: Ab1-28, Ab11-22 and Ab29-40. The images of FLIM without and with complex proved to be quite different, as well as their lifetimes. After determining the interaction of the complex with the peptide, the ability of the complex to influence the peptide aggregation process was investigated. Studies of circular dichroism at different stages of aggregation showed a significant difference in the ellipticity of the beta-sheet signals formed throughout the aggregation, suggesting a possible inhibitory effect by the complex. Studies with transmission electron microscopy were also performed with the fragments Ab1-40, Ab1-28, Ab11-22 and Ab29-40. Studies with Ab1-40 in the 1:5 complex:amyloid ratio did not show significant change over the control group. On the other hand, studies in the 1:1 complex:amyloid ratio show smaller aggregates, again highlighting the possibility of an inhibitory effect of aggregation.
Comportamento informacional e mineração textual no Twitter
(Universidade Federal de São Carlos, 2018-09-24)
Pinto, Guilherme Franco Silva
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Furnival, Ariadne Chloe Mary
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https://lattes.cnpq.br/1291482506649810
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https://lattes.cnpq.br/1848085408867454
This work aims to explore the information behavior of social media users, on Twitter specifically, at the moment they are searching and sharing information on Copyright Laws and its related subjects. Taking in consideration the social, cultural and economic changes that social media has made possible, this project will explore how the adapted Copyright Laws to digital platforms affect the usability of these platforms, and how its users seek information related to those adaptations. The Twitter API was used to collect the posts (tweets) made on the platform that are about Copyright and its related subjects, such as open licenses, Creative Commons, public domain, etc. Then, using Text Mining analysis in the statistical computing environment R, it was possible to assess and relate the terms and words used on these posts with the most common doubts and questions regarding Copyright. Finally, in this data it was possible to identify instances of information behavior of Twitter users during their interactions with each other and the information available on Twitter.
Modificação química de poli(ácido láctico) com monômeros vinílicos, por processamento reativo, visando ajuste molecular e sua utilização em blendas poliméricas
(Universidade Federal de São Carlos, 2018-09-24)
Rigolin, Talita Rocha
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Costa, Lidiane Cristina
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https://lattes.cnpq.br/8246109223926480
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Bettini, Sílvia Helena Prado
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https://lattes.cnpq.br/3687551763124327
Poly(lactic acid) (PLA) was modified with maleic anhydride (MA) or glycidyl methacrylate (GMA) in the presence of peroxide to assess the physical and chemical changes of the polymer during the reactive processing. Chemical modification of polymers with vinyl monomers can be seen as a great scientific challenge in order to obtain a material with adjustable physical and chemical properties due to changes in acidity, functionality and molar mass. The type of vinyl monomer (GMA and MA), peroxide (dicumyl peroxide and 2,5-dimethyl-2,5-di- (t-butylperoxy) hexane), pure or dispersed in CaCO3, and the monomer and peroxide concentration used were evaluated through an experimental design. Molar mass and acidity content were analyzed. Maleic anhydride grafting onto poly(lactic acid) (PLA) showed a decrease in the polymer molar mass and an increase in the acid content. However, when GMA is used in the functionalization of PLA, an increase in molar mass is observed with reduction of acidity of the polymer. PLA/PBAT blends were obtained in order to evaluate the efficacy of the chemical modification and the feasibility of the applied use of the modified PLA, either as the compatibilizer for the blend or as the matrix, depending on its molar mass and acidity content, in addition to in situ compatibilization with the different monomers. Oscillatory shear rheological tests and transmission electron microscopy (TEM) were used to evaluate how the different modified polymers performed in the morphology development and rheological properties of these blends. The morphology obtained was predominantly co-continuous and the viscosity ratio between the components predominated over a possible reduction of interfacial tension with the introduction of the vinyl monomers in the system. Results also showed that similar morphologies can be formed with the use of both monomers, GMA and MA, and that the procurement methodology of the blends can be adapted for the different monomers.
Ligação entre as propriedades estruturais, ópticas, eletrônicas e atividade fotocatalítica de Ag3PO4:Mo
(Universidade Federal de São Carlos, 2018-09-25)
Trench, Aline Barrios
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Longo, Elson
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https://lattes.cnpq.br/9848311210578810
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https://lattes.cnpq.br/5844795823690460
Silver phosphate (Ag3PO4) has received considerable attention from the scientific community due to photocatalytic and photoluminescent properties. However, some alternatives were sought to improve the performance of these properties by material modification, metal deposition, doping cation or anion or coupling with another semiconductor. In this sense, the objective of this study was the evaluation of the semiconductor Ag3(P1-xMox)O4 where Mo6+ was inserted in the crystalline structure in the form of doping. This process consists in the insertion of impurities in the structure of the solid at specific positions of the crystalline reticulum replacing the original structural units. It was also the objective of this study to synthesize the desired materials by chemical precipitation in aqueous medium and to relate the influence of the dopant on the structural, morphological, photoluminescent and photocatalytic properties together with theoretical calculations. The characterization of the samples was made by X-ray diffraction (XRD), ultraviolet-visible (UV-Vis) absorption spectroscopy, X-ray photoelectron spectroscopy, Raman spectroscopy, scanning electron microscopy (SEM), microscopy transmission electron microscopy (TEM), photoluminescence spectroscopy (PL) and theoretical calculations based on the Density Functional Theory. Photocatalytic tests were done for degradation of Rhodamine B under visible light irradiation. The samples with doping less than 2% did not present a second phase, demonstrating an effective doping, and changes in photoluminescence and band gap values showed that doping caused defects in the structure of the material, and these defects contributed to the photocatalytic improvement of the doped materials in comparison with pure material, the material being doped with 0.5% of Mo, which presented better results for degradation of Rhodamine B.
Efeito do treinamento de força realizado com duração de repetição controlada e auto-selecionada na força e massa muscular de homens jovens
(Universidade Federal de São Carlos, 2018-09-25)
Chaves, Talisson Santos
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Libardi, Cleiton Augusto
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https://lattes.cnpq.br/8953409094842074
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https://lattes.cnpq.br/8763654450242923
The aim of the study was to compare the effect of RD SELF, with and without total training volume equalized with RD CON, on muscle strength and hypertrophy. Twenty healthy untrained university students were recruited for this study. An intra-subject design was used in which the each participant’s leg was allocated in a randomized and balanced way: (1) Control RD (CON); (2) Self-selected RD with equalized volume (SELF-EV); Self-selected RD without equalized volume (SELF). All RT protocols were performed unilaterally using a conventional leg-extension machine, twice a week for 8 weeks. For the SELF and CON protocols, the participants performed 3 sets for muscle failure at 70% 1-RM, and 2 minutes rest period was granted between sets for both protocols. During SELF-EV, the same intensity and between-sets rest intervals were utilized, however, the number of sets varied (2-3 sets) due to TTV equalization with the CON group. Significant differences were found for TTV between protocols over 8 weeks (P = 0.0009), with SELF resulting in higher TTV compared to CON and SELF-EV. However, all training protocols showed significant increases in strength (P <0.0001) and muscle AST (P <0.0001), with no significant differences between groups (P> 0.05). In conclusion, resistance training with SELF RD, regardless of VTT, was equally effective in inducing increases in strength gains and muscle hypertrophy compared to RD controlled.
Sobrecarga dos cuidadores de crianças que necessitam de atenção especial à saúde: influência das demandas de cuidado e das práticas de atenção à saúde
(Universidade Federal de São Carlos, 2018-09-25)
Ferreira, Fernanda Yeza
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Okido, Aline Cristiane Cavicchioli
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https://lattes.cnpq.br/4358128584478380
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https://lattes.cnpq.br/4569284221808812
Objective: to explore the influence of care demands of children who need special attention to health and health care practices in the physical, emotional and social burden of caregivers. Method: observational, analytical, transversal design of a quantitative approach. 100 caregivers participated in the study, who answered the following research instruments: characterization tool; Burden Interview Scale for Informal Caregivers; Perception of Family-Centered Care- country version; Evaluation Instrument for Primary Health Care - Child Version. For statistical analysis, the Fisher's exact test, Spearman's correlation and univariate and multivariate linear regression analysis were used. Results: the majority of caregivers (57%) had moderate to severe overload. The mean score of physical, social and emotional overload was 47.99. Caregivers of children who require mixed care presented a 262.2 times greater chance of overload than caregivers of children who demand medication care. The domains of collaboration and support of the Family Centered Care Perception Scale - parents version, presented as factors associated with overload (p <0.05). In the multivariate linear regression model, the "longitudinality" variable maintained a significant relationship with the physical, social and emotional overload score of the caregivers of children who need special attention to health (p = 0.023). Conclusions: when recognizing the influence of care demands and health care practices on the caregivers' overload, the health professional can implement care strategies in order to reduce the burden and, consequently, increase the quality of care offered to these clients