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Qualidade de vida relacionada à saúde de homens submetidos à prostatectomia radical: comparação Brasil - Espanha
(Universidade Federal de São Carlos, 2019-11-28) Gomes, Cassia Regina Gontijo; Eduardo, Aline Helena Apolloni; https://lattes.cnpq.br/9804415222026713; Napoleão, Anamaria Alves; https://lattes.cnpq.br/8539664594837249; https://lattes.cnpq.br/9011528755378674
ntroduction: Prostate cancer (PC) is the third most common cancer in the general population, and the second most frequent among men from all over the world. Radical prostatectomy (RP) stands out as a therapeutic option for the localized PC. The main disadvantages of performing the surgery are the occurrence of urinary incontinence (UI) and sexual dysfunction (SD), which significantly impacts the health-related quality of life (HRQOL) of patients. Objective: To compare the HRQOL of Spanish and Brazilian men submitted to RP. Method: Multicentric, quantitative, descriptive, comparative and cross-sectional study conducted in Asturias (Spain) and Minas Gerais (Brazil). This study included patients undergoing RP after the removal of the bladder catheter and less than 24 months postoperatively. Data collection occurred through a socio-demographic, clinical and surgical characterization instrument, as well as two QOL instruments validated in Spain and Brazil, the World Health Organization Quality Life-Bref (WHOQOL-Bref) and the Expanded Prostate Cancer Composite Index (EPIC). Results: 160 prostatectomized Spanish and 165 Brazilians were evaluated. Among the participants in Spain, the averages of the scores of the general scale and of each WHOQOL-brief domain were: general (69.9), physical (80.0), psychological (79.2), social relations (63.1) and environment (88.5). In Brazil, the following averages were found: general (73.6), physical (78.0), psychological (82.2), social relations (68.0) and environment (81.1). In relation to the EPIC domains, the average values of the participants in Spain and Brazil were respectively: urinary (83.6 and 82.0), intestinal (97.0 and 98.7), sexual (31.9 and 38.6) and hormonal (90.9 and 94.5). In Spain, the aspects that most contributed to a better assessment of QOL were financial resources, access to information and opportunities for leisure activity. In Brazil, the factors that most favor a better perception of QOL by the participants were the absence of frequent feelings of bad mood, anxiety and depression, as well as a demonstration of resignation in relation to the decline in sexual function. Conclusions: In this study a better perception of HRQOL was found among Brazilian prostatectomized patients than among the Spanish.
Planejamento da rede de distribuição de medicamentos considerando custos logísticos e de ICMS
(Universidade Federal de São Carlos, 2019-11-28) Ramos, Cindy; Toso, Eli Angela Vitor; https://lattes.cnpq.br/6663631731115739; https://lattes.cnpq.br/3140066557446256
Medicines distribution planning in Brazil involves decisions of logistics network configuration, related to the location of distribution centers (DCs) and product flow among facilities. Medicines distribution planning in Brazil faces some challenges, due to medicines have many different characteristics, concerning to physical attributes (weight and volume), demand patterns and high value-added of the products. Other relevant issue is the Tax on Circulation of Goods and Services (ICMS). This tax depends on the value-added of the products and can significantly affect the distribution network planning. The ICMS is a non-cumulative tax, with rates that vary among states and results in a differentiated tax structure along the supply chain. In this work, we proposed an optimization model to support decisions of DCs location and the customer demand allocation to these DCs. We considered transportation costs, products of different values, interstate and intrastate rates and the matching credit (a tax benefit) offered by some Brazilian States. We used real data from a previous study and analyzed the solutions model to understand the relationships between logistics costs and taxation costs for each region/state. The allocation of lower value-added products depends more on logistics costs, while the allocation of higher value-added products is determine by the tax costs. However, a detailed assessment of the relationship between costs demystifies the advantage of tax benefits, especially for products where unit transport costs are higher than ICMS unit costs.
Uma proposta de introdução do aplicativo calculadora gráfica do geogebra para alunos do ensino médio
(Universidade Federal de São Carlos, 2019-11-28) Nogueira, Gabriel Nunes; Caetano, Paulo Antonio Silvani; https://lattes.cnpq.br/0370219014539994; Barbosa, Grazielle Feliciani; https://lattes.cnpq.br/5368292206467565; https://lattes.cnpq.br/6987783331238077
This dissertation presents the idealization, the application and the results of activities using the application "GeoGebra Graphing Calculator" for students of first and third years of high school in two schools in São Paulo State, Brazil, linked to Technical Education, addressing basic content of Analytical Geometry involving Points and Straight Lines. As an additional product of this work, several video lessons were developed to give virtual support to the idealized activities.