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Obtenção do sistema nanoestruturado livre de chumbo (Na0,5Bi0,5)0,94Ba0,06TiO3 (NBT-BT6) via rotas químicas
(Universidade Federal de São Carlos, 2020-09-16)
Silva, Gislayne Rayane Alves da
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Perdomo, Claudia Patricia Fernández
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https://lattes.cnpq.br/0062895903351287
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Kiminami, Ruth Herta Goldschmidt Aliaga
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https://lattes.cnpq.br/7643216999108223
Perovskites based on sodium bismuth titanate (Na0.5Bi0.5TiO3) are promising candidates for replacing some ceramic materials based on lead due to piezoelectric properties. The solid solution 0.94(Na0.5Bi0.5)TiO3-0.06BaTiO3 (NBT-BT6) can be highlighted as it shows the morphotropic phase boundary in this composition, where its dielectric and ferroelectric properties are maximized, as well as the piezoelectric coefficient. Most studies report the solid-state reaction as a method of obtaining this nanostructured system, which compromises its stoichiometry. Thus, this dissertation aims at the study the achievement of the NBT-BT6 through conventional hydrothermal synthesis and microwave-assisted routes and polymeric precursor - Pechini. In the hydrothermal synthesis, the study of the variation of the mineralizing concentration , time and temperature was carried out, whereas in the polymeric precursor - Pechini method, the temperature of the heat treatment of the dehydrated resin was the analyzed variable. In powders obtained under hydrothermal conditions, both conventionally and assisted by microwaves, the presence of the NBT and BT phases, and the anatase and brookite phases, after synthesis, were identified. Particles in cubic shapes and fibers were formed in both synthesis methods. The powders obtained via microwave-assisted hydrothermal route showed particles with a smaller average size and morphology with a greater presence of fibers, obtained in only 4% of the synthesis time, and after sintering at 900 °C for 2 hours they presented the NBT- BT6 phase and relative density of 87%. In samples synthesized by the polymeric precursor -Pechini method, the NBT-BT6 phase without secondary phases was obtained at 650 °C. In addition, the transformation of the phase at 260 °C, from rhombohedral to tetragonal, was observed for the formation of the solid solution NBT-BT6 indicating the presence of the morphotropic phase boundary and the beginning of crystallization at 450 °C, the lowest temperature reported in the literature.
Um estudo de caso sobre como a introdução de comportamentos adaptativos em uma aplicação web legada impacta a cobertura de código
(Universidade Federal de São Carlos, 2020-09-16)
Gentil, Rogerio Jeronimo
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Ferrari, Fabiano Cutigi
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https://lattes.cnpq.br/3154345471250570
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https://lattes.cnpq.br/7939047455945748
Context: Self-managing computer systems, also known as self-adaptive systems, are an alternative to get IT professionals free from details of operation and maintenance. Web applications can incorporate characteristics of a self-adaptive system, such as adaptation behavior at runtime, to respond to user needs, or to changes in context, in order to make them autonomous. However, one of the challenges of software engineering is to transform a legacy system into a self-adaptive system, in view of the costs and risks to replace a legacy system. Furthermore, as with any software evolution process, the introduction of adaptive behavior can lead to the insertion of faults in the legacy system. This way, the code coverage information produced by software tests assist in activities related to the evolutionary maintenance of the system. Objective: In this work, we analyzed, through the comparison of coverage metrics, how the introduction of adaptive behaviors in a real world legacy web application impacted code coverage. Method: In order to have a minimum percentage of coverage, for each scenario implemented, a set of test cases was created in the legacy version of the web application. Then, evolutionary versions were develop with the introduction of the adaptive behaviors to the application. The versions (legacy and adaptive) were organized into branches of the version control system so that adaptive implementations have evolved in two technological ways. The coverage metrics for each version of the web application were collected, after re-running the set of test cases created, and tabulated to allow data analysis. Results: The coverage of six versions of the web application with behavior characteristic of self-adaptive systems, in addition to the legacy version, were analyzed and compared between the respective implementation scenarios. Conclusion: The results indicate that the impact on the total code coverage is relevant, where even relatively small changes can considerably affect, either positively or negatively, the percentage of coverage of the changed unit.
O trágico como limiar do desencanto: o apocalipse em O livro dos homens sem luz, de João Tordo
(Universidade Federal de São Carlos, 2020-09-17)
Ruy, Igor Fernando
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Valentim, Jorge Vicente
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https://lattes.cnpq.br/4427303771174064
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https://lattes.cnpq.br/6524414036072929
This essay presents the sensations of the end of the world in the novel O livro dos homens sem luz (2004), by the contemporary Portuguese writer João Tordo (1975-). At first, it approaches the Portuguese author in the opening, mentioning his strategy of literary insertion, through a universal thematic of disenchantment with the human condition, whose strategy of rereading of the past allows a different and less utopian look at the advances in contemporary times. This perception obviously passes through artistic production and, thus, realization in literature, through the exercise of verisimilitude with fiction, the utopian impact of a demand for a social transformation of well-being that has not been completely consolidated. As a result, this essay deals with the construction of this theme through the tragic as a conductive element of a dysphoric action in postmodernity. It discusses the configuration of the end of the world feelings based on losses that lead to the tragic action. João Tordo’s novel, therefore, leads to a reflection on the representation of space and time in the narrative and the conditioning forces in the elaboration of the end of the world, with triggering processes of the type of conduct in the presence of tragic action, in addition to the tendency to rupture with the social ordering processes, determined in the moral sphere, thus thematizing an anti-utopian discourse. Finally, the network of ambiences and catastrophic environments result in a critical look at social relations that, although configured in the fictional scope, reflects the disbelief in the resolution of the frustrations interposed in daily life, establishing melancholy as a connecting thread to the notion that we are near the end of the world.
Resistência ao escorregamento de revestimentos cerâmicos: avaliação por diferentes métodos, correlações com a topografia e o desgaste da superfície durante o uso
(Universidade Federal de São Carlos, 2020-09-17)
Lot, Ana Virgínia
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Melchiades, Fábio Gomes
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https://lattes.cnpq.br/4469106561041487
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Boschi, Anselmo Ortega
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https://lattes.cnpq.br/3259846931278607
The development of ceramic floors for safe use in environments associated with slip and fall accident risks, which are even higher in the presence of water and contaminants, deals with the following difficulties: 1) although some roughness increase may contribute to the slip resistance of the surfaces, on the other hand, this can make them more susceptible to grime and wear. 2) there is a wide variety of methods for evaluating and classifying tiles as recommended or not for use in slip-risk areas and results of different methods may disagree between them. 3) satisfactory slip performances of floors measured before installation may not be maintained during their use. In this sense, the objective of this work was to contribute to the development of safe and durable ceramic floors by identifying the characteristics of the surfaces related to their performance and investigating how they vary over time. Several types of commercial floors were characterized regarding their slip resistance - with the DS, BOT-3000 and Pendulum devices - and staining resistance. The results were correlated with roughness parameters obtained by profilometers for the identification of the surface’s characteristics relevant to their performance. The samples were subjected to heavy traffic, to accelerate their wear and grime, and re-evaluated. Surface changes were observed, such as reductions in average roughness and profile amplitude and inclination, as well as the increase in the spacing between irregularities and rounding of their shapes. Consequently, all the high initial slip resistance surfaces presented a deterioration of this property in the three methods of evaluation. Surface aspects were also associated with tendency to grime and a new complementary analysis to the usual laboratorial method for predicting ceramic floors cleanability was proposed.
O Centro Educacional São José Operário em São Luís do Maranhão (1988-2015): confessionalidade e laicidade
(Universidade Federal de São Carlos, 2020-09-17)
Rodrigues, Maria José Lobato
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Nunes, Iran de Maria Leitão
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https://lattes.cnpq.br/2313634756775278
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Bittar, Marisa
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https://lattes.cnpq.br/3059723520472948
This study analyzes the trajectory of Centro educacional São José operário (CESJO), founded by the Congregation Poor Servants of Divine Providence, in Maranhão capital, in 1988, to attend the sons of poor families from the periphery of São Luís. As a philanthropic confessional school, the CESJO express, by one side, elements that fundament the educative and caritive intentions of the catholic church, and, by other, when being financed with public resources, the secularity of the state. In this sense, the analysis is justified by permit comprehend the catholic interaction present in the school inside of the context of secularity of the state in the education. The study self insert in the field of history of education and, more specifically, in the line of the educational institutions where we search for theoretical. Methodolocally, we stablished as temporal mark the period of time between 1988 and 2015 (27 years) by the possibility to reconstruct the tragetory of the institution and the transformations in which it passes nowadays. The study self insert in the field of history of education and, more specifically, in the line of the educational institutions, Aiming documental intersection using different sources, among them, the writings, iconographicals and orals, being that the interviews were of absolute importance especially by the fact of many pratices and experiences lived by different individuals in the school being only registred in their memories.The Congregation when creating the school found in the sucularity of the State the guarantees to offer for the society assistencial support and confessional school education that stablished their bases in the work as educative principle. CESJO’s confessional identity was marked by a set of rites and practices (disciplining, prayer, religious teaching classes, sacred symbols, religious festivities, congregational charism, spiritual formation), which, in turn, built own school culture that influenced the identity and worldview of their subjects. CESJO over three decades has changed its relationship with the State: between 1988-2003 it was configured as a philanthropic confessional school that received public resources; in 2004 it was inserted in the public education network; in 2015 the school building was rented to SEDUC-MA. The relationship he established with the public authorities since 2004 and the socio-cultural influences interfered with his confessional character and christian identity, making him characterized as a public school with elements of catholic confessionality. CESJO’s trajectory shows that the State-religion relationship produced a secularity in education marked by the influence and manifestation of religious elements in public spaces, what sustain the validity of christian educaction inside the education system.
Eficácia da utilização da solução custodiol versus a solução celsior como métodos de preservação do enxerto no transplante cardíaco
(Universidade Federal de São Carlos, 2020-09-17)
Fernandes, Marcio Pimentel
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Machado, Regimar Carla
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https://lattes.cnpq.br/1310723429860987
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https://lattes.cnpq.br/4775278598894188
Heart transplantation may be the only treatment opportunity for those individuals with end-stage heart disease. Heart preservation is currently limited to 4 hours in cold ischemia storage using preservation solutions, and is an indispensable factor for graft function and survival in transplantation. The mortality rate is mainly related to graft failure in transplantation, so that techniques capable of improving graft function can directly influence the patient's survival. Objective: To analyze in the scientific literature the efficacy between custodyol versus celsior solution as the best method of graft preservation in heart transplantation. Method: This is an integrative review of the literature, directed according to the structure of PICOS, followed by research in the electronic databases: Pubmed, Virtual Health Library and Embase, to research the articles. As keywords we use heart transplantation and its synonyms, Celsior, and Cutodiol and its synonyms. Results: In all, 22 studies were analyzed, of which only 4 were included in the review, one clinical trial, one meta-analysis and two retrospective studies. Mortality and myocardial dysfunction after heart transplants were investigated. Conclusion: After the analysis of the articles under study, it was not possible to identify between the two solutions Celsior and Custdiol a superiority of one over the other in post-transplant mortality and graft dysfunction after transplantation.
Influência do uso e cobertura do solo sobre a ictiofauna de riachos das cabeceiras do Alto Rio Paranapanema
(Universidade Federal de São Carlos, 2020-09-17)
Almeida, Rodrigo da Silva
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Cetra, Maurício
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https://lattes.cnpq.br/6775493342513120
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https://lattes.cnpq.br/4423449163037358
Human activities have generated unprecedented impacts on aquatic biodiversity. Thus, knowing the impacts generated by these activities is extremely important, as fish from the Neotropical regions represents approximately 1\5 of the world's fish species, or perhaps 10% of all vertebrate species on the planet. Agricultural activities cause changes in the landscape and, depending on land use, they can reduce permeabilization and percolation, increase runoff, increase in sedimentation, fragmentation of forests, and the entry of pollutants into the watercourse. These effects cause changes in the stream structure and, consequently, affect the fish communities. However, different types of land use do not promote identical changes in aquatic systems, so the effects on fish communities will be differentiated. Understanding the direct and indirect effects that affect the structure of fish assemblages is of great relevance, moreover, in studies that include several factors: land-use and land-cover (LULC), stream structure, geographic and spatial (watercourse distance). These types of studies promote the expansion of knowledge to support conservation measures. The present study aims to answer whether there is a relationship between land use for agricultural activities and fish assemblages and to test whether these relationships are dependent on the spatial scale. The study was conducted in the southeastern of the Rain Forest in an extension of approximately 240 km from the Upper Rio Paranapanema Basin. Sampling was carried out in 30 streams of headwaters that include stretches of 2nd to 5th order. Satellite images were acquired to carry out the classification of land-use and land-cover. Redundancy analyzes (RDA) were applied to test the relationship between land use and composition and paths analyses to test direct and indirect relationships between land use and the richness of stream fish species. The results showed that there is a relationship between land use and the composition and richness of fish species, but it is dependent on the spatial scale adopted. The analysis of partition of variance and redundancy showed that in the catchment scale most of the variation in LULC was explained together with by geographic and spatial factors indicating intercorrelation between these two sets of variables. There was a relationship between local environmental variables and LULC on the catchment scale. The RDA test showed that there is a relationship between composition and local environmental variables and spatial factors. There is an indirect relationship between the richness of fish species and land use, but it depends on the type of use practiced. The species were associated with the type of land use. Generalist species are more common in streams whose catchment has higher anthropic pressure. Our work indicates that the hierarchical concept is valid to identify the environmental factors that affect the composition of the fish assemblages. This study highlights the importance of catchment management in the preservation of stream fish. The work also indicates that agriculture has a greater indirect (negative) effect on the fish richness and that different types of land use indirectly affect the fish richness of streams, as the land use on the watershed scale contributes to the alteration of the stream structure, which consequently affects the assembly of stream fish.
Treinamento suspenso vs. treinamento de força tradicional: efeitos na massa muscular, força e desempenho funcional em idosos
(Universidade Federal de São Carlos, 2020-09-18)
Soligon, Samuel Domingos
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Libardi, Cleiton Augusto
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https://lattes.cnpq.br/8953409094842074
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https://lattes.cnpq.br/8700846438138378
Purpose We compared the effects of suspension training (ST) with traditional resistance training (TRT) on muscle mass, strength and functional performance in older adults. Methods Forty-two untrained older adults were randomized in TRT, ST (both performed 3 sets of whole body exercises to muscle failure) or control group (CON). Muscle thickness (MT) of biceps brachii (MTBB) and vastus lateralis (MTVL), maximal dynamic strength test (1RM) for biceps curl (1RMBC) and leg extension exercises (1RMLE), and functional performance tests (chair stand [CS], timed up and go [TUG] and maximal gait speed [MGS]) were performed before and after 12 weeks of training. Results MTBB increased significantly and similarly for all training groups (TRT: 23.35%; ST: 21.56%). MTVL increased significantly and similarly for all training groups (TRT: 13.03%; ST: 14.07%). 1RMBC increased significantly and similarly for all training groups (TRT: 16.06%; ST: 14.33%). 1RMLE increased significantly and similarly for all training groups (TRT: 14.89%; ST: 18.06%). MGS increased significantly and similarly for all groups (TRT: 6.26%; ST: 5.99%; CON: 2.87%). CS decreased significantly and similarly for all training groups (TRT: -20.80%; ST: -15.73%). TUG decreased significantly and similarly for all training groups (TRT: -8.66%; ST: -9.16%). Conclusion ST promotes similar muscle mass, strength and functional performance improvements compared to TRT in older adults.
UVC-based advanced oxidation processes for water treatment: laboratory and pilot plant scale studies
(Universidade Federal de São Carlos, 2020-09-21)
Sánchez Montes, Isaac José
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Aquino, José Mario de
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https://lattes.cnpq.br/8847710280926769
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https://lattes.cnpq.br/8426184376549148
The challenge of providing good-quality water free from contaminants of emerging concern (including organic microcontaminants; OMCs) and pathogens is one of the main hot topics worldwide. Thus, the efficiency of different UVC-based advanced oxidation processes (UVC AOPs) to remove organic pollutants and/or inactivate pathogens under distinct experimental conditions was investigated. At laboratory scale, UVC/HClO process showed the best performance for the degradation and mineralization of BPA containing solutions, while the UVC/S2O82– process had a better efficiency in comparison to UVC/H2O2. This behavior is due to the generation of high oxidation power radicals (mainly HO• and SO4•−) by the activation of H2O2, S2O82–, and HClO under UVC light. Considering the oxidation by-products generated, no organochlorine compounds were detected (after 6 h) using UVC/HClO contrasting to the results obtained using only HClO (two organochlorines were detected). In addition, taking into account the environmental (experimental and theoretical toxicity tests) and economical parameters investigated, the UVC/HClO method showed a higher efficiency under low operating costs. However, under complex experimental conditions, more mature technologies such as UVC/H2O2 and UVC/S2O82− are recommended. In this sense, simultaneous elimination of six OMCs (ACT, CAF, CBZ, TMP, SMX, and DCF) and three bacteria (E. coli, E. faecalis, and S. enteritidis) by UVC/H2O2 and UVC/S2O82− processes from a simulated municipal wastewater effluent were successfully investigated at pilot plant scale. UVC AOPs were compared in terms of the required treatment time to remove at least 80% of the sum of OMCs, bacterial inactivation and regrowth, and energy consumption. UVC treatment alone was not suitable mainly due to the very slow and incomplete removal of OMCs, while UVC/H2O2 and UVC/S2O82− were effective to simultaneously eliminate OMCs and bacteria; however, in comparison with the UVC/S2O82 system, the UVC/H2O2 process did not exhibit bacterial regrowth under dark conditions. According to these results and taking into account some environmental regulations, reclaimed water treated with the UVC/H2O2 process is a real alternative for water reuse purposes in many activities, for instance, in agriculture since this activity demands the highest freshwater consumption worldwide. Finally, a simple model based on the Beer–Lambert law enabled reasonable estimation of the oxidant concentration required to attain maximum oxidation rates (i.e., shortest reactions time).
Comportamento de fluência e tração a quente do aço inoxidável austenítico AISI 201LN
(Universidade Federal de São Carlos, 2020-09-21)
Pelissari, Gustavo Henrique
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Sordi, Vitor Luiz
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https://lattes.cnpq.br/8364164402481940
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https://lattes.cnpq.br/3463198633564863
Among the different stainless steel (SS) series, the 200 series, also known as Cr-Ni-Mn alloys, has recently been gaining prominence worldwide. In spite of that, studies addressing the high-temperature deformation these alloys are still scarce in the literature. In this context, this study aims to assess the mechanical and microstructural behavior under deformation of the AISI 201LN alloy when subjected to creep and hot tensile tests. The material was microstructurally characterized as received and after heat treatment. The tensile tests were conducted at room temperature and in the range of 500-800 °C under an initial deformation rate of 10-3s-1, whereas the creep tests were performed under constant load in the temperature range of 600-800 °C. Comparison between the results obtained for the AISI 201 LN alloy and those for other 300 series traditional materials showed very similar values. After the tensile tests at room temperature, a mostly martensitic microstructure, caused by transformation induced plasticity (TRIP), was observed. After the creep tests, evidence of precipitation of Cr carbides was observed in the grain boundaries of some specimens. The long period of exposure to high temperatures changed the morphology of the δ ferrite islands, indicating decomposition of this phase. In the tests performed at 800 °C, formation of precipitates rich in N was observed on the surface of specimens, in addition to intense deterioration of their microstructure. Overall, fracture surface analysis of the specimens indicated a gradually greater predominance of ductile fracture in the tests at higher temperatures. Based on the Zener-Hollomon parameter, constitutive equations were proposed to describe the creep behavior of the material within the range of stresses and temperatures employed. The Larson-Miller creep parameterization technique was applied to the experimental data set aiming to extrapolate from the creep results.
Cartografando gêneros: tempos e espaços da não-binaridade
(Universidade Federal de São Carlos, 2020-09-22)
Baena, Pâmela Keiti
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Lana, Rita de Cássia
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https://lattes.cnpq.br/1816504631940006
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https://lattes.cnpq.br/0457602425911721
La categoría de género se introdujo en las humanidades en el siglo XX como clave de interpretación, influenciada por las teorías feministas (SCOTT, 2019), para comprender cómo se establecían las relaciones de poder entre hombres y mujeres en diferentes tiempos y espacios. Sin embargo, hay tradiciones en las que la división que se entiende occidentalmente como género no es binaria. Estas tradiciones, muchas nativas y no occidentales, a veces comprenden un tercer o varios géneros para sujetos que ocupan diferentes funciones sociales. Este parece ser el caso de las llamadas muxes, consideradas un tercer género que se da en el municipio indígena de Juchitán de Zaragoza, México. Ahora bien, partiendo del supuesto de que las concepciones de género pueden ser diferentes a lo largo del tiempo y también en el espacio, surge la pregunta: ¿es posible pensar en los géneros más allá de una perspectiva binaria? Utilizando la concepción de la “trialética” del espacio propuesta por Henri Lefebvre, conectando bibliográficas e iconográficas en el momento de la investigación, divididas en dos etapas fundamentales: relevamiento de fuentes y aplicaciones. La discusión conceptual tuvo como objetivo reflexionar sobre el tema de la colonialidad y sus posibles contribuciones al creciente área de la geografía y el género. Luego, se realizó una investigación sobre los géneros no binarios y no occidentales encontrados en la bibliografía y, considerando su distribución espacial en todo el mundo, se elaboró una tabla para aprehender la amplitud de los datos obtenidos. Finalmente, se ingresó a la región del Istmo de Tehuantepec para comprender cómo se inserta en el contexto contemporáneo el llamado “tercer género” mexicano de muxes, los espacios percibidos, concebidos y vividos, trabajamos con fuentes que no se ajusta al modelo binario y tiene especificidades en cuanto a los roles sociales que deben ejercer los sujetos en la comunidad. Se concluye que ligados a la ascendencia indígena, la dinámica de las fiestas juchitecas y el sistema de reciprocidad social, las muxes están en las fronteras entre el proyecto tradicional y el colonialista, resistiendo como espacios de existencia y, según Lefebrvre, produciendo un espacio diferencial.
Controle das respostas cardiovasculares ao estresse pela neurotransmissão endocanabinóide no núcleo leito da estria terminal em ratos: interação com a via de sinalização receptor NMDA/nNOS/GCs/proteína quinase G e envolvimento do hipotálamo lateral
(Universidade Federal de São Carlos, 2020-09-23)
Souza, Lucas Gomes de
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Crestani, Carlos Cesar
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https://lattes.cnpq.br/1117432571971568
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https://lattes.cnpq.br/6248063137017709
The bed nucleus of the stria terminalis (BNST) is a structure located in the rostral forebrain, which has been implicated in autonomic, neuroendocrine and behavioral responses during aversive situations. A recent study from our group showed an inhibitory influence of endocannabinoid signaling within the BNST, acting through the local CB1 receptor, in the tachycardia induced by acute restraint stress, but with no effects on the arterial pressure increase and the sympathetic-mediated cutaneous vasoconstriction. Based upon that, one of the objectives of this work was to evaluate the involvement of NMDA glutamatergic receptor and local nitric oxide (NO) signaling in the control of cardiovascular responses to acute restraint stress by BNST endocannabinoid neurotransmission BNST. We observed that CB1 receptor antagonism in the BNST increased the release of nitric oxide (NO) during acute restraint stress. In addition, bilateral microinjection of the selective CB1 receptor antagonist (AM251) into the BNST facilitated the tachycardic response, but with no effects the pressure response and the cutaneous tail temperature drop induced by acute restraint stress. The facilitation of the tachycardic response to acute restraint stress caused by treatment with the selective CB1 receptor antagonist in the BNST was completely abolished after local pretreatment with a NMDA selective glutamatergic receptor antagonist (LY235959), as well as with selective inhibitors of the enzymes neuronal nitric oxide synthase (NPLA) and soluble guanylate cyclase enzyme (ODQ) and protein kinase G (KT5823). Our results suggest that endocannabinoid neurotransmission in the BNST inhibits local glutamatergic neurotransmission via NMDA/nNOS/sGC/protein kinase G signaling; and this mechanism is involved in the control of tachycardiac response to stress. We also assessed the involvement of GABAergic neurotransmission in the lateral hypothalamus (LH) in the control of cardiovascular responses to acute restraint stress by BNST CB1 receptors. Experiments of characterization of LH GABAergic neurotransmission revealed that bilateral microinjection of a selective GABAA receptor antagonist (SR95531) into the LH, but not a selective GABAB receptor antagonist (CGP35348), reduced the tachycardia response to acute restraint stress, but without affecting the pressor responses and the drop in tail skin temperature. These findings indicated that GABAergic neurotransmission in the LH, acting through local GABAA receptors, plays a facilitatory role in the tachycardic response to restraint stress. Evaluation of the participation of LH GABAergic neurotransmission in HL in the control of cardiovascular responses to acute restraint stress by CB1 receptor in BNST revealed that microinjection of the selective CB1 receptor antagonist into the BNST decreased the neuronal activation of LH neurons during acute restraint stress. Besides, facilitation of tachycardia caused by acute restraint stress following microinjection of AM251 into the BNST was abolished by pretreatment with a selective receptor antagonist GABAA (SR95531) in the LH. Finally, we investigated the involvement of CB1 and CB2 receptors in the BNST in innate anxiety and anxiogenic response to acute restraint stress. Analysis of gene expression revealed the expression of both CB1 and CB2 receptors in the anterior and posterior divisions of the BNST. Intra-BNST microinjection of the selective CB1 receptor antagonist (AM251) increased the open arms exploration of the elevated plus-maze (EPM) in naive animals and inhibited the anxiogenic effect observed in the EPM triggered by acute restraint stress. On the other hand, intra-BNST microinjection of a selective CB2 receptor antagonist (JTE907) dose-dependently increased the innate anxiety in the EPM and inhibited the anxiogenic response evoked by restraint. These results indicate that CB1 and CB2 receptors present in the BNST are involved in the control of innate anxiety and anxiogenic responses evoked by stress.
Reconfigurações de modelos de gestão: o caso das empresas familiares no Brasil
(Universidade Federal de São Carlos, 2020-09-23)
Soulé, Fernanda Veríssimo
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Grün, Roberto
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https://lattes.cnpq.br/6028266827740491
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Sacomano Neto, Mário
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https://lattes.cnpq.br/0000793038362058
This study examines the reconfiguration in the moral structures that support family business models of management, relating them to the transformations in the ideologies of capitalism. Studies in the sociological institutionalism that investigate historical changes in models of management mostly describe dominant models in different periods. From this lens, the family model would have lost its ability to provide justifications for mobilizing and engaging individuals. However, this research demonstrates that family businesses not only survived but went through processes of reorganization that allowed them to remain central to the functioning of capitalism. Inspired by Luc Boltanski’s sociology of critical capacity, I assessed the changes over time in the normative content about and for these companies using three datasets. Supported by Voyant, Mallet, R-Studio, and Prospero software, I analyzed 51 Brazilian handbooks focused on family businesses published from 1978 to 2018. I also carried out participant observation in twelve events aimed at family businesses and nine semi-structured interviews with key actors, as executives, heirs, consultants, and academics, in the United States and Brazil. I identified instruments and moralities that allowed family businesses to remain important over three periods. In the first, there was the emergence of the category of family business in the social space of management, which is associated with industrial capitalism. The second period was marked by the influence of financialization in the companies’ and families’ way of organizing. Finally, the centrality of connectionist capitalism in the current reconfiguration of this model became dominant in the last period. The results revealed that the changes in the most relevant forms of value in capitalism reflected in the emergence of new concepts in the social space of family businesses, such as professionalization, governance, holding, family office, entrepreneurship, networks, and legacy. Overall, the research concludes that dominant models of management do not necessarily exclude former ones. When they are able to reshape, as in the case of family businesses, they may become more robust.
O narrador e as personagens femininas em Badu (1932), de Arnaldo Tabayá
(Universidade Federal de São Carlos, 2020-09-24)
Bosco, Bianca
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Marques, Wilton José
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https://lattes.cnpq.br/5763590592946918
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https://lattes.cnpq.br/8161532130383273
The following dissertation wants to rescue the literary work called Badu (1932), written by the Brazilian author Arnaldo Tabayá (1901-1937). Being this one the only novel released by the writer, it received a lot of recognition from the critics by the time of its release, although many positive critics were not enough to stop that both the author and the book were forgotten in the following years. It is made, roughly, a general panorama from the tales and poems that Tabayá writes in newspapers, before and after the novel’s publication, so the reader can be familiar with his literary production. Also, it is important to consider the criticism and review the book received by that time. The truth is that, until today, not many deep analyses were made from Badu (1932), especially considering the historical and literary context in which Brazil found itself. Knowing that, it is necessary to revisit and relate the social aspects and the characteristics from the 1930’s Brazilian Novel, when many important books were launched. This literary movement is known for prioritize, by literature, the representation from the reality of the country, not hiding its imperfections and exploring aspects that were not problematized by then. Badu (1932) is important that way, because, by being part of this movement, it draws attention to problems from Rio de Janeiro’s society, where the novel happens. The image middle class men had from women is one of the main points explored in Tabayá’s narrative, in which the narrator represents the masculine view over the feminine universe. Using Luís Bueno’s (2015) terms, the reducing roles imposed to women were the prostitute and the wife, no half term – and restlessness caused by the nonconformity it was not exclusivity from Badu (1932), but from many 1930’s novels. The study object still has many female characters that show a lot more depth and meaning that the narrator can show and see, and not only the ones he relates romantically, but also his relates and acquaintances. Even with the big gap between the book’s release and current days, many of the criticism made by the author are very relevant nowadays and can be used to comprehend 1930’s society a little bit more, fact that shows its importance and then it fits as a member from the 1930’s Brazilian novel.
Eficácia da instilação de células da linhagem MB49 e gel polimérico termorreversível na imunização contra o carcinoma urotelial de bexiga
(Universidade Federal de São Carlos, 2020-09-24)
Santana, Jhonne Pedro Pedott
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Borra, Ricardo Carneiro
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https://lattes.cnpq.br/5655362515357840
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https://lattes.cnpq.br/7058366901763632
Among the various types of malignant neoplasms, those originating in the bladder can be considered highly impactful due to their prevalence and high recurrence rates, demonstrating the importance of studies involving new therapeutic possibilities. The MB49 cell line is one of the most used for the study of bladder cancer, through its urinary bladder implantation in murine models of tumor induction. Studies have shown that heat shock proteins, such as mortalin, are vital for resistance to the treatment of neoplasms and are present in all processes associated with carcinogenesis. However, there are still not many studies focused on the use of mortalin as a therapeutic target in urothelial bladder carcinoma. Heat shock proteins are also known to play an important role as mediators of immunogenicity. Activating the immune system for therapeutic benefit has long been a goal in immunology, especially in cancer treatment. Antitumor immunotherapy is a promising treatment against several types of cancer, however the low immunogenicity of vaccines remains a limiting factor in this area. Thus, research involving the investigation of the association of these vaccines with immunogenic adjuvants, such as chitosan, is of great relevance for the study of cancer. This thesis aims to: evaluate the pattern of protein expression of mortalin in tumor bladder tissues, using a western blot assay; the investigation of its inhibition effects with MKT-077 on the viability, apoptosis and necrosis of MB49 cells, through viability tests with resazurin and fluorescence; the establishment of a new murine model for the induction of urothelial bladder carcinoma using a thermoreversible polymeric gel (TPG), composed of chitosan and poloxamer; and the identification of the induction of systemic anti-tumor immune response, through a splenocyte cytotoxicity assay, after intravesical inoculation of TPG and MB49 cells. Female mice of the C57BL/6 strain were obtained and used in intravesical tumor cell inoculation procedures. It was observed that mortalin is overexpressed in tumor bladder samples. After the inhibition of mortalin, there was an irreversible reduction in the viability of MB49 cells, promoting an increase in the rates of apoptosis and necrosis in these cells. Antitumor immunotherapy using MB49 cells embedded in a TPG matrix was able to stimulate systemic immune response and affect the development of bladder urothelial carcinoma in an orthotopic and syngeneic murine model.
Atenção em HIV/AIDS na Atenção Básica: um estudo da rede de Rio Claro
(Universidade Federal de São Carlos, 2020-09-24)
Peixoto, Cacilda
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Fioroni, Luciana Nogueira
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https://lattes.cnpq.br/8086810053892035
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https://orcid.org/0000-0002-2311-7848
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Bellenzani, Renata
Acquired Immunodeficiency Syndrome (AIDS) corresponds to the clinical manifestation of infection by the Human Immunodeficiency Virus (HIV). Despite advances in the fight against the HIV / AIDS epidemic, it remains a public health problem, with significant data on morbidity and mortality and obstacles that need to be overcome. In view of the global scenario that points to high levels of HIV contamination and the need to offer actions aimed at reducing the spread of the disease, starting in 2003, the process of decentralizing HIV testing and counseling in primary care has intensified, allowing greater coverage and accessibility, and so far this action has been centralized in specialized care services. In this context, the study aimed to evaluate HIV / AIDS care in primary care, under the evaluative opinion of professional nurses. This is a research with a quantitative approach. The participants were 22 nurses who work in the Basic Health Units and Family Health Strategy in the city of Rio Claro / SP. Data were collected through a questionnaire from October 2019 to January 2020 and analyzed by calculating the Average Ranking (RM), Cronbach's alpha coefficient and descriptive statistics through the SPSS (Statistical Package for the Social Sciences) programs and STATA (Statistical Software). The results showed a weakness in the performance of the units in relation to the domains: Health Education, Permanent Education in Health and Prevention of Sexually Transmitted Infections. It was observed that the units perform a very satisfactory work in relation to actions such as: the provision of rapid testing, provision of protective supplies (condoms), prevention of vertical HIV transmission and early diagnosis, thus valuing the ability of AB in actions that can weaken the spread of the virus infection. It is signaled that the best performances were expressed in those more standardized actions, with a tendency to standardization and of a more technical character, when compared to actions of a more procedural, communicational nature and that require singularization of approaches focusing on specificities and needs. Thus, it is necessary to advance in comprehensive care and, in particular, in prevention that integrates the technical protocol domains with the psychosocial and educational domains in health, with regard, above all, to the approach to the experiences of sexuality, diverse and plural, to the mitigation of stigma of AIDS and social and health inequities. We emphasize, therefore, that the implementation of new structural, technological and procedural arrangements, as well as the interactions between managers, health professionals and users, should focus on overcoming difficulties and implementing humanized and resolutive practices in the control of the HIV epidemic / AIDS at this level of care.
On the advances in pattern recognition using Optimum-Path Forest
(Universidade Federal de São Carlos, 2020-09-24)
Sugi Afonso, Luis Claudio
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Papa, João Paulo
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https://lattes.cnpq.br/9039182932747194
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https://lattes.cnpq.br/0686979081263816
Pattern recognition (PR) techniques have been paramount to solve different and complex problems in many fields of study. The basic idea behind PR techniques is to compute a model capable of classifying unknown samples. Pattern recognition can be categorized as problems of (i) supervised, and (ii) unsupervised learning. This categorization is related to the existence or absence of labeled data to support the learning process. The learning process is mandatory for PR techniques to learn the data distribution, and the existence of labeled data is an additional information that helps to build more robust models. Many techniques were proposed and are well-established in the literature. The Optimum-Path Forest (OPF) is a graph-based classifier proposed recently, which comprises the models for supervised, semi-supervised and unsupervised learning. The OPF models dataset samples as nodes of a graph and their connections (edges) are defined by some pre-defined adjacency relation. Although very recent, OPF has already been employed in numerous applications and showed promising results, and even outperformed other well-known classifiers. Nonetheless, there is still a lot to be investigated, evaluated and proposed concerning the use and performance of the OPF classifier. This dissertation investigates e proposes variations and modifications to the traditional OPF algorithms concerning supervised and unsupervised learning aiming the assessment of its performance in not yet explored scenarios and to overcome its drawbacks.
Modelo de avaliação do nível de maturidade das tecnologias da indústria 4.0 aplicado ao setor sucroenergético
(Universidade Federal de São Carlos, 2020-09-24)
Marinho, Clésio Aparecido
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Oprime, Pedro Carlos
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https://lattes.cnpq.br/9291517431456908
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https://lattes.cnpq.br/5085639529900865
The intensification of digital technologies in the industrial environment may require new management practices in the context of the Fourth Industrial Revolution, also known as Industry 4.0. It is believed that such technologies are capable of increasing the competitiveness of companies, as well as facilitating human/machine interaction and integration between customers and suppliers in the production chain. This dissertation aims to evaluate how the industrial processes of the energy sector are implementing the technologies and concepts of Industry 4.0, considering the technological, managerial and strategic bottlenecks. For this, a literature review was conducted, from which it was possible to identify seven models of maturity for Industry 4.0. The in-depth analysis of these publications resulted in the construction of a maturity model directed to the sugar-energy sector. The proposed model contains five dimensions: Strategy, Data Management, Work Teams, Vertical Integration and Horizontal Integration. The operationalization of this maturity model is based on the structure of the National Quality Award. To empirically test this model, a case study was conducted in two companies in the sugar-energy sector. This study captured the interviewees' perception of the implementation of the concepts and technologies of Industry 4.0 in industrial processes. The results revealed that the companies participating in the research are already applying the concepts of industry 4.0 in the management of their industrial processes, so that the evaluated companies obtained 731 and 788 points out of 1000 possible, and that the proposed maturity model can help the development of digital transformation strategies in organizations in the sugar-energy sector.
Trabalho, subjetividade e identidade dos Institutos Federais de Educação, Ciência e Tecnologia: análise de um caso sui generis
(Universidade Federal de São Carlos, 2020-09-24)
Loureiro, Thiago
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Silva, Eduardo Pinto e
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https://lattes.cnpq.br/3492708361349827
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https://lattes.cnpq.br/4158791619972447
The present study sought to understand the organizational identity of IFSP São Carlos, as well as the work and subjectivity of its professors. To this end, it preliminarily resorted to the history of the RFEPT in the different historical moments of the country, and then focused on the most recent model – the IF, conceived and implemented since 2008, during Lula government. This is a case study with qualitative guidance based on Psychodynamics at Work, Psychosociology and Social Psychology. To address the professor’s work and subjectivity, the study included the application of a survey to a total of thirty-three respondent professors, followed by ten semi-structured interviews with members of the faculty from all branches of IFSP São Carlos. In addition, two administrative employees were also interviewed. The twelve interviews were analyzed through content analysis. When analyzing IFSP São Carlos, it was found that the institution’s constitution, since its implantation, as CEFET, it was related to political aspects which involved federal, municipal and UFSCar management. In this sense, the intrinsic relationship with UFSCar, makes IFSP São Carlos a unique case of the Network. In the institution, two moments of changes in its development and its organizational identity were identified, both permeated by disputes and interest and, specifically, by power relations between the technological branches, as well as their political correlations. This took place when the company moved to its own headquarters in 2016 and with the effectuation of High School activities integrated in 2017, which had not yet been implemented. It was noted idiosyncrasies and ambivalences related both to the multiform demands of work, as well as to the management tools that guide the teaching workload. Although it was not the motto of the study, voices from administrative servants were accessed, a fact that led to the understanding of an intensified work widespread in the institution, some with serious consequences for their subjectivism, as well as for psychic and psychosomatic health. The current political and governmental moment in the country, antagonistic to the education project that generated the FIs, also contributed to such developments. Although the pleasurable experiences of the faculty and institutional careers are evident, they do not immunize these professional from psychic burden derived from a complex and permeated by contradictions daily life. However, the current moment of IFSP São Carlos, in its new facilities and with the cultural change resulting from the consolidation of Integrated High School, has brought IFSP São Carlos closer to the beacons recommended by the RFEPT and a possible identity better suited to its legal conception – politics, although subject to forges and disputes. It is concluded that the transitions and metamorphoses of the IFSP São Carlos organizational identity occurred interspersed with disputes, idiosyncrasies and ambivalences. Such identity– organizational changes reverberate in the socially assigned and subjectively appropriate identities of professors. These also metamorphose, in some cases, in a sublimatory way, in others, giving rise to suffering, conflicts, stress, stress and/or illnesses. In other words, the hybridity and metamorphoses of IFSP São Carlos have repercussions and generate different implications for the idiosyncrasies and contradictions of teaching subjectivities.
Estudo sistemático da condutividade iônica de vitrocerâmicas NASICON: influência de tratamentos isotérmicos e novas substituições iônicas
(Universidade Federal de São Carlos, 2020-09-24)
Ortiz Mosquera, Jairo Felipe
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Rodrigues, Ana Candida Martins
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https://lattes.cnpq.br/4499231813051400
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https://lattes.cnpq.br/6700527765785171
The synthesis of solid electrolytes and the optimization of their ionic conductivity are topics of scientific interest since these components are essential for the current density and the half-life of the sodium batteries. The NASICON (Na super-ionic conductor) materials belong to the most promising candidates to solid electrolytes because their 3D structural framework favors the migration of ions. The glass-ceramic route allows the synthesis of NASICON compounds with the advantages of reducing porosity and controlling the microstructure, which are relevant factors in the optimization of ionic conductivity. Thus, in this doctoral thesis NASICON glass-ceramics of the Na1+xAlxGe2-x(PO4)3 (NAGP), Na1+xGe2(SiO4)x(PO4)3-x (NGSP) and Na3.4AlxSc2-xSi0.4P2.6O12 (NAScSP) series have been synthetized. Isothermal heat-treatments of crystallization were performed on NAGP precursor glasses to analyze their effect on structural and electrical properties of the crystallized samples. It was noted that the extensive dealumination of the NASICON phase with the increase of the treatment time does not affect the electrical properties of the material due to the formation of a conductive Na7(AlP2O7)4PO4 phase and a greater contact area between the grains of the glass-ceramics. In the NGSP NASICON series, it was evaluated the effect of Si4+/P5+ substitution on structural and electrical properties of the glass-ceramics. It was confirmed the increment in the ionic conductivity due to the expansion of the unit cell of the NASICON structure and the increase of Na+ ions. In the NAScSP series, it was proven that the addition of Al2O3 favors the glass-forming ability and affects the ionic transport in the material due to a decrease in the bottleneck of NASICON structure.