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Heart rate variability dynamics in women with urinary incontinence: a systematic review
(Universidade Federal de São Carlos, 2022-01-05) Silva, Jordana Barbosa da; Abreu, Raphael Martins de; Padilha, Juliana Falcão; Silva, Audrey Borghi; Catai, Aparecida Maria; Driusso, Patricia; https://lattes.cnpq.br/8898319491890063
Introduction and hypothesis Sympathetic and parasympathetic pathways of the autonomic nervous system (ANS) regulate the lower urinary tract. The aim of the present study was to synthesize the evidence regarding ANS regulation in women with urinary incontinence (UI) evaluated through heart rate variability (HRV). Methods This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Five databases were researched in April 2021 (PubMed, CINHAL, Scopus, Web of Science and Cochrane Library) and included cross-sectional studies in full-length publications in the English language. Studies assessed the HRV during bladder filling (group A) and after voiding (group B). The Joanna Briggs Institute (JBI) checklist was applied for methodological quality assessment purposes. Results A total of 920 articles were identified and 5 studies were included. Most studies analyzed the HRV by linear indexes. Studies from group A (n = 2) presented fair methodological quality; one study from group B (n = 3) showed fair methodological quality (Im et al. Korean J Urol. 51:183, 2010) whereas the others presented high methodological quality. One study from group A found an increase in both modulations between women with overactive bladder (OAB) versus women with stress UI, whereas a decrease was reported between incontinent and continent women. Studies from group B showed a decreased sympathetic and parasympathetic modulation in AOB with detrusor overactivity (DO), whereas one study found an increase in both modulations in women with OAB compared with stress UI. Conclusion Parasympathetic and sympathetic modulation increased during bladder filling and rest in UI with OAB associated or not with DO. Both modulations decreased during bladder filling in incontinent women and during rest in OAB.
A primavera veio e foi embora, nove anos acabaram tão rápido: Uma descrição e narração crítico-reflexiva da graduação em Medicina na Universidade Federal de São Carlos
(Universidade Federal de São Carlos, 2022-01-05) Dias, Marcos Fracarolli; Barbosa Neto, Jair Borges; https://lattes.cnpq.br/9551566039906499
The undergraduate medical course of the Federal University of São Carlos has the objective to create physicians according to the National Curriculum Guidelines, which guide the shaping of the intended physician profile: a generalist one, with humanistic, critic and reflexive posture, capacitated to act on the health-disease process, on the areas of health promotion, prevention, recovery and rehabilitation. This publication is written in the form of a critical-reflexive narrative coupled with description of the trajectory of an undergraduate student, from his joining in medical school in 2013, until his leaving with a degree in 2022. Summarily describes the main activities done by the author as well as the main obstacles faced on his way and the obstacles faced by his colleagues and peers. Tells the story of all his undergraduate years as well as considerations due to the pandemic of the severe acute respiratory syndrome coronavirus 2, which began in 2019 and has effects up until the date of this publication.
Cross-cultural adaptation and measurement property analysis of the Brazilian Portuguese version of the Three Incontinence Questionnaire
(Universidade Federal de São Carlos, 2022-01-05) Alem, Michele Elisabete Rubio; Silva, Jordana Barbosa da; Beleza, Ana Carolina Sartorato; Chaves, Thais Cristina; Driusso, Patricia; https://lattes.cnpq.br/8898319491890063
Introduction and hypothesis The differential diagnosis of urinary symptoms may allow health professionals to establish a therapeutic objective and to choose the appropriate treatment for the patient's complaint. The aim of this study was to cross-culturally adapt the Three Incontinence Questionnaire (3IQ) into Brazilian Portuguese (3IQ-Br) and to analyze test-retest reliability, construct, and criterion validity in women. Methods The cross-cultural adaptation of the 3IQ-Br included forward-translation, back-translation, and consensus among an expert committee. Participants with and without urinary incontinence (UI) completed the 3IQ-Br, King's Health Questionnaire (KHQ), and Questionnaire for Female Urinary Incontinence Diagnosis (QUID-Br). Only women with UI answered 3IQ-Br after 7–10 days. Test-retest reliability and construct validity were analyzed using the Cohen linear kappa (k). The 3IQ-Br accuracy was analyzed using the area under the curve (AUC) of the receiver-operating characteristic (ROC) curve, considering the sensitivity and specificity to correctly classify women with and without UI. Results The reliability of each question from the 3IQ-Br was considered substantial in the test-retest. The agreement among 3IQ-Br, QUID-Br, and KHQ was almost perfect for UI diagnosis (k > 0.8). The 3IQ-Br was considered to have good accuracy in distinguishing women with UI considering the KHQ (AUC 0.83, 95% confidence interval [CI] 0.78 to 0.87, p < 0.001), and fair to the QUID-Br (AUC 0.73, 95% CI 0.68 to 0.78; p < 0.001). Conclusions The results of this study showed that this version of the 3IQ-Br has acceptable measurement properties for identifying and differentiating UI symptoms in Brazilian women.
Geometric invariants of groups and property R-infty
(Universidade Federal de São Carlos, 2022-01-05) Sgobbi, Wagner Carvalho; Wong, Peter Ngai-Sing; https://lattes.cnpq.br/9104201992938700; Vendrúscolo, Daniel; https://lattes.cnpq.br/8602232587914830; https://lattes.cnpq.br/8536818102991005
In this thesis we study property R_\infty for some classes of finitely generated groups by the use of the BNS invariant \Sigma^1 and some other geometric tools. In the combinatorial chapters of the work (4, 5, 6, 10 and 11), we compute \Sigma^1 for the family of Generalized Solvable Baumslag-Solitar groups \Gamma_n and use it to obtain a new proof of R_\infty for them, by using Gonçalves and Kochloukova's paper. Then, we get nice information on finite index subgroups H of any \Gamma_n by finding suitable generators and a presentation, and by computing their \Sigma^1. This gives a new proof of R_\infty for H and for every finite direct product of such groups. We also show that no nilpotent quotients of the groups \Gamma_n have R_\infty. With a help of Cashen and Levitt's paper, we give an algorithmic classification of all possible shapes for \Sigma^1 of GBS and GBS_n groups and show how to use it to obtain some partial twisted-conjugacy information in some specific cases. Furthermore, we show that the existence of certain spherically convex and invariant k-dimensional polytopes in the character sphere of a finitely generated group G can guarantee R_\infty for G. In the geometric chapters (7 through 9), we study property R_\infty for hyperbolic and relatively hyperbolic groups. First, we give a didactic presentation of the (already known) proof of R_\infty for hyperbolic groups given by Levitt and Lustig (which also uses a paper from Paulin). Then, we expand and analyse the sketch of proof of R_\infty for relatively hyperbolic groups given by A. Fel'shtyn on his survey paper: we point out the valid arguments and difficulties of the proof, exhibit what would be a complete proof based on his sketch and show an example where the proof method doesn't work.