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Papel do córtex pré-frontal medial na ansiogênese induzida pelo estresse de derrota social em camundongos
(Universidade Federal de São Carlos, 2018-10-18)
Recent findings have demonstrated that the medial prefrontal cortex (mPFC) has a lateralized role in the control of response to stressors, and the left hemisphere (LmPFC) would attenuate the anxiogenic responses elicited ...
Papel dos receptores vaniloides TRPV1 da matéria cinzenta periaquedutal na ansiedade e na antinocicepção induzida pelo medo em camundongos
(Universidade Federal de São Carlos, 2013-05-03)
When confronted with fear situations rodents exhibit behavioral (e.g., fight, flight, immobility and vocalization) and neurovegetative (tachycardia, hypertension and defecation) responses that characterize the defense ...
O papel dos receptores 5-HT1A e 5-HT2C da substância cinzenta periaquedutal sobre os efeitos da fluoxetina na antinocicepção induzida pelo confinamento de camundongos aos braços do labirinto em cruz elevado
(Universidade Federal de São Carlos, 2015-03-20)
The pain is an universal experience, and frequently follows anxiety and depression cases. Some specific drugs used in depression and anxiety treatment are also used for the relief of pain. There are evidences showing that ...
Avaliação do papel dos receptores 5-HT3 da substância cinzenta periaquedutal de camundongos submetidos ao labirinto em cruz elevado
(Universidade Federal de São Carlos, 2009-04-24)
The exposure of animals to aversive situations, such as elevated plus-maze (EPM), activates serotonergic pathways with projections into structures involved in the defense system, such as the amygdala, septum, hypothalamus, ...
Avaliação pancreática de animais submetidos à dieta hiperlipídica
(Universidade Federal de São Carlos, 2012-09-04)
The pathogenesis of type 2 diabetes mellitus (DM2) is associated with insulin resistance (IR) and pancreatic β cells (β cells) defect. Adipose tissue modulates metabolism by releasing free fatty acids (FFA), ...
Os sistemas serotonérgico, gabaérgico e endocanabinoide da amígdala medeiam a empatia relacionada à nocicepção em camundongos
(Universidade Federal de São Carlos, 2020-08-28)
Evidence shows a reciprocal relationship between chronic pain and emotional disorders, exacerbating the other's experience. The affective-emotional component of pain can be activated not only in those who feel the pain but ...
Avaliação do papel da amídala na antinocicepção induzida pelo medo : análises comportamental, imunoistoquímica e farmacológica
(Universidade Federal de São Carlos, 2017-05-30)
Exposure of rodents to an open elevated plus maze (oEPM, an EPM with all four open arms) elicits antinociceptive responses, high level of plasma corticosterone and defensive behaviors. However, very little is known about ...