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Avaliação de comportamentos relacionados a ansiedade, autoadministração de etanol e expressão de pró-dinorfina e Fos em regiões encefálicas de animais adultos expostos à nicotina durante a adolescência
(Universidade Federal de São Carlos, 2014-07-07)
Adolescence marks a period of increased vulnerability to drug abuse. Early initiation of tobacco use is strictly associated with alcohol use and dependence in adolescence and adulthood. The present study aims to investigate: ...
Avaliação da função cardíaca in vitro do cascudo Hypostomus regani (IHERING, 1905) e dos efeitos da exposição a concentrações subletais do pesticida Fipronil (REGENT 800WG®)
(Universidade Federal de São Carlos, 2014-09-03)
Fipronil (Fpn) is a phenyl-pyrazolic insecticide widely used for pest control in agriculture and livestock. It can be applied in very low doses as well as very high concentrations for the effective control of insects that ...
Mecanismo de ação da cedrelona na morte celular programada de células de câncer de mama
(Universidade Federal de São Carlos, 2015-03-30)
Cancer is among the leading causes of death in the world and breast cancer is the type of cancer that affects more women. The treatment of this disorder requires a careful selection of one or more methods of intervention. ...
Efeitos antitumorais da naringenina complexada com cobre (II) e 2,2 -bipiridina em células de câncer de mama
(Universidade Federal de São Carlos, 2014-05-07)
Cancer, is the name given to a set of more than 100 diseases that have in common the uncontrolled growth of cells that invade tissues and organs. It is occurs for several reasons, among them changes in DNA that may be ...
Efeito da exposição à atrazina nas brânquias de Poecilia vivipara aclimatados a diferentes salinidades
(Universidade Federal de São Carlos, 2013-06-28)
Atrazine is an herbicide widely used in agriculture, cause morphological and biochemical changes in organs of many species. The estuarine environments are highly dynamic under constant variations of physicochemical water. ...
Distribuição e orientação dos quimiorreceptores de O2 branquiais em tilápia-do-Nilo (Oreochromis niloticus): controle das respostas cardiorrespiratórias à hipóxia
(Universidade Federal de São Carlos, 2012-08-31)
In fish the O2 chemoreceptors are mainly found in the gill arches and monitor the O2 tensions (PO2) of the inspired water (externally oriented) and/or the arterial blood (internally oriented). During hypoxia these receptors ...
Efeitos da alimentação e digestão na contratilidade miocárdica de pítons (Python molurus)
(Universidade Federal de São Carlos, 2013-02-28)
Despite all the knowledge about the excitation-contraction coupling (E-C) in mammals, there are still large gaps in the knowledge of the cardiac myocytes physiology in other vertebrates. Thus, the study of groups underexplored ...
Efeitos da alimentação/digestão e do jejum prolongado sobre a função cardíaca de cascavéis, Crotalus durissus terrificus
(Universidade Federal de São Carlos, 2012-09-14)
Some snakes have the ability to survive long periods without food and are capable to ingest large meal size. The ingestion of proportionally large preys triggers an expressive increase on the oxidative metabolic demand ...
Avaliação dos efeitos do resveratrol sobre o tecido ósseo de ratas ovariectomizadas
(Universidade Federal de São Carlos, 2014-05-06)
Resveratrol (trans 3,5,4 'trihydroxystilbene) is a polyphenol found in some plants and fruits. There are indications that it may be associated with the prevention of osteoporosis due to its action similar to a SERM (Selective ...
Inibição da síntese de óxido nítrico reduz termogênese durante a inflamação sistêmica induzida por LPS em pintainhos
(Universidade Federal de São Carlos, 2014-08-29)
Low and high LPS doses (endotoxin) have been used as models to study fever and endotoxic shock, respectively. In rats, systemic nitric oxide (NO) directly affects thermogenesis, but does not mediate those responses. Even ...