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Viabilidade dos géis a base de quitosana como adjuvantes no tratamento tópico do câncer urotelial de bexiga com imunoterápico: revisão da literatura
(Universidade Federal de São Carlos, 2024-02-06)
Despite recent advances in the areas of prevention and treatment, urothelial bladder cancer remains a challenging condition, holding significant positions in the global ranking of secondary neoplasms. Conventional therapeutic ...
Avaliação do potencial biotecnológico de Streptomyces sp. para biocontrole de fungos fitopatogênicos de espécies agrícolas de importância econômica: biocontrole de fitopatógenos por Streptomyces sp.
(Universidade Federal de São Carlos, 2024-02-07)
Fungi are the phytopathogens that most substantially affect global agricultural productivity. The development of sustainable strategies and approaches for the control of phytopathogenic fungi and their respective diseases ...
Identificação e expressão recombinante de um novo peptídeo de potencial antimicrobiano derivado da proteína de reconhecimento de Peptidoglicanos 3 humana
(Universidade Federal de São Carlos, 2024-02-20)
During the 21st century, bacterial resistance to drugs has reached dangerous levels, necessitating the development of new therapeutic strategies to combat these pathogens. Among them, antimicrobial peptides (AMPs) emerge ...
Expressão, purificação e caracterização estrutural dos mutantes truncados da Hsp70-escort protein 1 humana
(Universidade Federal de São Carlos, 2024-02-15)
The 70 kDa Heat shock protein (Hsp70 or HSPA in humans) is a highly conserved family of molecular chaperones that is expressed in various cellular compartments and is associated with several pathologies, including ...
Bases bioquímicas e funcionais dos mecanismos de resistência do ensitrelvir e nirmatrelvir contra polimorfismos naturais protease principal de SARS-CoV-2.
(Universidade Federal de São Carlos, 2024-02-05)
The pandemic caused by SARS-CoV-2 has brought various challenges to society, affecting the world socially and economically. After the first cases of COVID-19 were recorded in China, the virus spread rapidly, leading millions ...
Impressão 3D para fins de reparo ósseo: uma revisão da literatura
(Universidade Federal de São Carlos, 2024-02-15)
Bone fractures are a common condition that can affect people of all ages, often caused by trauma such as falls or accidents, or by diseases. The bone healing process is highly regulated, involving cells and growth factors. ...
Caracterização das alterações transcricionais e morfológica da mitocôndria da prole de fêmeas obesas com deficiência da mitofusina 2 no oócito
(Universidade Federal de São Carlos, 2024-01-26)
Heart disease is one of the main causes of death worldwide and research has shown an intrinsic relationship between cardiac effects in offspring and maternal obesity. In addition, there is increasing evidence of the possible ...
Caracterização pan-câncer da expressão de genes relacionados ao adesoma em células únicas de tumores humanos
(Universidade Federal de São Carlos, 2024-02-16)
Cancer is one of the main challenges when it comes to public health systems around the world, with a significant increase in the number of cases expected in the next three years, including in Brazil. The set of adhesion ...
Expressão heteróloga e caracterização de mananases da família GH5
(Universidade Federal de São Carlos, 2024-02-02)
Polysaccharides in plant cell walls are mainly composed of cellulose, a glucose homopolymer, and hemicellulose, a complex group of heterogeneous polymers and one of the largest sources of renewable organic matter, with ...