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Localização subcelular da DSCR2, uma proteína relacionada à síndrome de Down.
(Universidade Federal de São Carlos, 2003-10-17)
Down Syndrome (DS) is the major cause of mental retardation with a high incidence among human beings. Main features in DS include facial and
dermatological features, congenital heart defects as well as immunological, ...
Clonagem e caracterização molecular da fosforribosil pirofosfato sintase (PRPP sintase) de cana-de-açucar.
(Universidade Federal de São Carlos, 2002-11-22)
Phosphoribosylpyrophosphate synthetase (PRS - EC: 2.7.6.1) is an enzyme of central importance in several metabolic pathways in all cells. So far the plant PRS enzymes have not been investigated in great detail. However, ...
Proteoma da peçonha de Lachesis muta rhombeata
(Universidade Federal de São Carlos, 2013-02-25)
O efeito da desintegrina DisBa-01 e do silenciamento da integrina avB3 e na interação de células tumorais e endoteliais in vitro
(Universidade Federal de São Carlos, 2013-02-27)
Metastasis depends on several physiological processes such as cell adhesion, transendothelial cell migration and proliferation. These events are mediated mostly by integrins, which are adhesion receptors present on cell ...
Análise da expressão gênica das peroxirredoxinas em pacientes com deficiência de glicose-6-fosfato desidrogenase e doença falciforme por hemoglobina SC
(Universidade Federal de São Carlos, 2014-02-04)
Reactive oxygen species (ROS) are produced by the organism under various circumstances, such as the incomplete reduction of oxygen during cell respiration and also by exogenous factors. Have certain roles in the body, ...
Produção recombinante e caracterização de duas cistatinas de cana-de-açúcar
(Universidade Federal de São Carlos, 2014-09-05)
Cystatins are reversible inhibitors of cysteine peptidases. The cystatins found in plants are called phytocystatins, and represent an independent subfamily of the cystatins superfamily. Some studies have reported significant ...
Produção recombinante e caracterização de uma legumaína de cana-de-açúcar
(Universidade Federal de São Carlos, 2014-09-04)
Cysteine proteases (CPs) are proteolytic enzymes which have a cysteine residue at its active site. Plant legumains are CPs known as vacuolar processing enzymes and they play key roles in seed maturation, germination, ...
Estudos estruturais e ensaios biológicos de proteínas codificadas por genes de micro-exon (MEG) de Schistosoma mansoni
(Universidade Federal de São Carlos, 2014-09-05)
Schistosoma mansoni is the causative agent of Schistosomiasis, reaching 249 million people in 78 countries. It is believed that this infection is successful due to modulation of the host immune system through proteins ...
Construção e caracterização de uma enzima quimérica obtida pela fusão gênica endoglucanase-xilanase de Trichoderma harzianum
(Universidade Federal de São Carlos, 2013-02-05)
The sugarcane bagasse is a lignocellulosic material that can be converted into ethanol by action of cellulases and xylanases. These enzymes act synergistically to convert cellulose and hemicellulose into glucose. In order ...
Efeitos de uma desintegrina recombinante de Bothrops alternatus, DISBA-01, em células precursoras miogênicas (CPM)
(Universidade Federal de São Carlos, 2009-09-21)
Disintegrins are toxins commonly found in snake venoms whose biological effects occour upon interaction with surface receptors known as integrins. DisBa-01, an RGD disintegrin isolated from a cDNA library made with mRNAs ...