Buscar
Mostrando ítems 1-10 de 52
Estudo químico do fungo Colletotrichum acutatum e sua interação com Citrus sinensis
(Universidade Federal de São Carlos, 2014-11-06)
Brazil remains the world's largest orange producer, accounting for 32% of the total production of oranges and 50% orange juice. The State of São Paulo holds 97% of Brazilian exports of orange juice, possessing one of the ...
Reações multicomponentes de Diels-Alder com parabenzoquinonas : intermediários para Sesquiterpenos Eudesmanos
(Universidade Federal de São Carlos, 2010-09-20)
In the first part of this thesis we describe the study of the oxidation of phenols to p-benzoquinones. The metal complexes used as catalysts in this study are: [CoII(salen)], [CoII(dmsalen)], [CoII(salpn)], [CoII(dmsalpn)], ...
Integração de métodos in silico e in vitro para o planejamento de inibidores da enzima cruzaína
(Universidade Federal de São Carlos, 2011-06-30)
Chagas disease, caused by the flagellate protozoan of the family Trypanosomatidae Trypanosoma cruzi, is endemic in Latin America. The available drugs are ineffective and cause severe side effects. Therefore, it is necessary ...
Síntese e avaliação da atividade biológica de compostos N-Heterocíclicos
(Universidade Federal de São Carlos, 2011-07-28)
N-heterocyclic compounds have a large number of biochemical and medical applications and an important role in the discovery of new drugs, and many of best sellers, currently in use, contains one or more N-heterocyclic ...
Estudo químico em patógenos e vetores de doenças de citros: Xylella fastidiosa e Diaphorina citri
(Universidade Federal de São Carlos, 2011-07-04)
CHEMICAL STUDY OF PATHOGENS AND VECTORS DISEASE OF CITRUS: Xylella fastidiosa & Diaphorina citri. Historically the national citriculture suffered great changes because of phytosanitary problems, and nowadays among the main ...
Aplicação das técnicas espectroscópicas e quimiométricas no estudo do controle de qualidade das drogas vegetais: embaúba, malva e ginseng brasileiro
(Universidade Federal de São Carlos, 2010-05-14)
In the last few years the phytotherapy has emerged as a drug form well accepted and accessible, causing the increase in demand for drugs based on plants throughout the world, becoming an attraction for the pharmaceutical ...
Estudo de metabólitos secundários de Ruta graveolens como inibidores da fotossíntese
(Universidade Federal de São Carlos, 2012-12-09)
In this work were isolated eighteen secondary metabolites from Ruta graveolens (Rutaceae), eleven alkaloids (five akridonic, five quinolinics and one quinolonic) and seven furanocoumarins. Thirteen compounds had their ...
Ressonância magnética nuclear ultrarrápida: implementação, desenvolvimento e aplicações
(Universidade Federal de São Carlos, 2011-11-24)
This work highlights the implementation, development and application of the Ultrafast Nuclear Magnetic Resonance (UFNMR) technique, proposed by Frydman and co-workers. Through this technique, it is possible to perform ...
Estudo da atividade biológica do motivo ECD do domínio tipo-desintegrina da botropasina
(Universidade Federal de São Carlos, 2011-05-10)
Integrins are cell surface receptors that mediate cell adhesion and platelet aggregation, although they do part of important physiological processes in the organism, are also related pathologies such as tumorigenesis, ...
Ensaios bioquímicos e celulares para a identificação de novos inibidores de TcGAPDH seletivos à HsGAPDH
(Universidade Federal de São Carlos, 2011-08-11)
Chagas disease is a tropical neglected illness; nearly 10 million people are infected, in 2008 it was responsible for the deaths of about 10 thousand people. At present, only two medicines (benznidazol and nifurtimox) are ...