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Now showing items 11-20 of 26
Ensaios bioquímicos e celulares para a identificação de novos inibidores de TcGAPDH seletivos à HsGAPDH
(Universidade Federal de São Carlos, 2011-08-11)
Chagas disease is a tropical neglected illness; nearly 10 million people are infected, in 2008 it was responsible for the deaths of about 10 thousand people. At present, only two medicines (benznidazol and nifurtimox) are ...
Estratégias sintéticas para a preparação de novos fotossensibilizadores do tipo ftalocianinas
(Universidade Federal de São Carlos, 2013-02-28)
In this work some studies about the synthesis of a new Znphthalocyanine derivative containing 8 tert-butyl groups on peripheral positions were performed. In order to obtain this compound, a new monomeric unit were synthesized ...
Investigação do potencial antimicrobiano de Casearia sylvestris sobre microrganismo endossimbionte de Diabrotica speciosa
(Universidade Federal de São Carlos, 2013-03-27)
Diabrotica speciosa is a pest insect which occurs in most Brazilian states, standing out as one of the most important polyphagous pest of in grain crops. The understand of the role of the microbiota present in the digestive ...
Desenvolvimento de métodos para estudo de dioxinas presentes na cinza do bagaço da cana-de-açúcar : avaliação do potencial biorremediador de cepas microbianas em compostagem aeróbica
(Universidade Federal de São Carlos, 2012-03-30)
Sugarcane bagasse ash is a byproduct of sugar and alcohol industry with potential for field application. However, the presence of organic contaminants such as dioxins turns necessary the development of strategies for removal ...
Planejamento e avaliação de fragmentos moleculares como inibidores da enzima cruzaína
(Universidade Federal de São Carlos, 2015-08-24)
The available drugs for treating Chagas disease are not
effective, therefore the development of new therapies is needed. Cruzain is the major
Trypanosoma cruzi cysteine protease, the causative agent of the disease, and ...
Estudo do perfil químico de Cyperus rotundus e avaliação do seu potencial de absorção de metais
(Universidade Federal de São Carlos, 2016-07-27)
The following work describes the comparative study of the variation between chemical profiles of plants of the Cyperus rotundus species – where one was collected at Vale S.A.’s dumping ground in Canaã dos Carajás city, ...
Estudos fitoquímicos e avaliação da atividade antitumoral de extratos vegetais de Casearia sylvestris nanoencapsulados
(Universidade Federal de São Carlos, 2013-03-26)
The term cancer refers to neoplasias that are characterized by uncontrolled growth of cells that have some kind of genetic mutation. Prostate cancer is the cancer with the highest incidence in men. In its initial phase, ...
Químio-, régio- e estereosseletividades das reações de Diels-Alder de para-benzoquinonas: um estudo teórico
(Universidade Federal de São Carlos, 2014-07-23)
In this work, some computational theoretical studies on the reactivity of para-benzoquinones and their derivatives in Diels-Alder reactions were proposed These studies were done in order to compliment the corresponding ...
Técnicas de bioinformática aplicadas ao estudo de poligalacturonases de fungos
(Universidade Federal de São Carlos, 2012-04-18)
Plant cell walls are composed of approximately 65% cellulose microfibrils and pectin. The latter is proteolytically degraded by the so-called pectinases enzymes (also known as pectinolytic enzymes). Pectinases may be either ...
Metátese de fechamento de anéis de derivados da R-(-)- Carvona
(Universidade Federal de São Carlos, 2012-03-21)
In this work was developed a new synthetic route to obtain cicloeptenone not conjugated selectively, through a faster and simpler methodology, and in accordance with good practices of green chemistry. By experimental ...