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Estudos químicos e microbiológicos de microrganismos associados à esponja marinha Dragmacidon reticulatum, objetivando o isolamento de metabólitos secundários bioativos
(Universidade Federal de São Carlos, 2010-04-22)
Fungi are known as one of the most promising sources of unprecedent bioactive compounds, however, marine derived fungi are still very poorly studied. These microorganisms present high percentages of active metabolites and ...
Efeito anti-inflamatório do extrato etanólico da Harpagophytum procumbens durante a inflamação intestinal de camundongos infectados com Salmonella Enteritidis (ATCC13076)
(Universidade Federal de São Carlos, 2014-05-29)
Salmonellosis is an illness caused by bacteria of the genus Salmonella, a leading infectious disease worldwide. Due to the importance of this infection forward to eating habits, the search for a new compound that can ...
Avaliação do efeito do extrato etanólico bruto de Harpagophytum procumbens em camundongos infectados com Toxocara canis
(Universidade Federal de São Carlos, 2012-02-29)
The Syndrome of Visceral Larva Migrans (VLMS) is a parasitic disease caused by Toxocara canis, one of the most common helminthes in dogs. In the definitive hosts are present in different morphological forms, embryonated ...
Avaliação de formas de preparação de estoques de trabalho na preservação de Streptomyces clavuligerus visando a produção de ácido clavulânico
(Universidade Federal de São Carlos, 2008-08-28)
A great deal of microbiological and genetic research in the pharmaceutical industry is directed towards the development of effective strategies in the handling of microorganisms
seeking the production of antibiotics that ...
Estabelecimento de meios de cultura para o cultivo de Streptomyces isolados de sedimento marinho
(Universidade Federal de São Carlos, 2009-10-16)
Microorganisms represent an important source for production of bioactive metabolites for diverse applications. The production of these substances is directly related to the culture medium associated with sources of carbon ...
Ação da laserterapia de baixa intensidade (830nm) na regeneração muscular de ratos idosos
(Universidade Federal de São Carlos, 2009-03-13)
The elderly still go through physical changes, especially musculoskeletal disorders such as sarcopenia, changes in central and peripheral nervous system, blood hypoperfusion,
regenerative changes contributing to atrophy ...
Modelagem molecular de derivados pirimidínicos e estudos de docking nas enzimas ciclooxigenase 1 e ciclooxigenase 2
(Universidade Federal de São Carlos, 2010-11-23)
In this research molecular docking was used to study enzime-ligand complexes of Cyclooxygenase 1 (COX-1) and Cyclooxygenase 2 (COX-2) with pyrimidine derivatives, aiming at understanding the possible mechanisms of action ...
Comparação entre histologia e espectroscopia de fluorescência para avaliação de atrofia cutânea induzida por glicocorticóide em ratos
(Universidade Federal de São Carlos, 2010-09-24)
The gold standard for evaluating skin atrophy is the histological study. When compared to the technique of Fluorescence Spectroscopy (FS), histology requires the physical removal of tissue and their processing in the ...
Docking de herbicidas na glutationa transferase tau4-4 de soja (Glycine max)
(Universidade Federal de São Carlos, 2011-03-30)
This study, based on molecular docking, describes the search for the most favorable conformations when complexes between herbicides, used in soybean cultivation, and an enzyme involved in the detoxification process are ...
Produção recombinante e estudos funcionais de uma cisteíno peptidase de Xanthomonas citri subspécie citri
(Universidade Federal de São Carlos, 2009-04-29)
The citrus canker disease is caused by a phytopathogenic bacterium Xanthomonas citri ssp. citri (Xac). The common symptoms are defoliation, twig die-back and premature fruit drop. The infection process of this bacterium ...