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Bioprospecção e purificação de substâncias bioativas produzidas por Streptomyces tubercidicus, endofítico isolado de Solanum lycocarpum St. Hill (Lobeira) do cerrado de São Carlos-SP
(Universidade Federal de São Carlos, 2009-12-11)
The need for new and useful compounds to provide assistance and relief in all aspects of human condition is ever-growing. Drug resistance in bacteria, the appearance of life-threatening viruses, and the increase in the ...
Otimização das condições de cultivo de Erysipelothrix rhusiopathiae para produção de vacina contra erisipela suína
(Universidade Federal de São Carlos, 2007-03-30)
Swine erysipelas is one of the diseases responsible for the great economic losses in swine-producing areas of the world. The bacteria Erysipelothrix rhusiopathiae is the causative agent of erysipelas, and the vaccines ...
Os efeitos do Biosilicato® e do laser terapêutico de baixa potência no processo de consolidação em tíbias de ratos
(Universidade Federal de São Carlos, 2009-12-21)
Fractures of delayed consolidation and fractures with non-union are commonly found in medical practice and are associated with high morbidity and mortality. Within this context, biochemical and biophysical resource have ...
Inteligência computacional aplicada à automação de biorreator para produção de Penicilina G Acilase (PGA)
(Universidade Federal de São Carlos, 2008-07-11)
Biotechnology has presented, in the last years, a rapidly growing development. New biotechnological industrial processes are constantly introduced using different microorganisms and/or enzymes. In this context, the application ...
Estudo comparativo de precursores da PpIX (ALA e MAL) utilizados topicamente em terapia fotodinâmica
(Universidade Federal de São Carlos, 2008-08-08)
Photodynamic therapy (PDT) is a modality for treatment of tumors, and uses a combination of a drug (photosensitizer) and light in the presence of the molecular oxygen to selectively damage target tissue. In the absent of ...
Avaliação de formas de preparação de estoques de trabalho na preservação de Streptomyces clavuligerus visando a produção de ácido clavulânico
(Universidade Federal de São Carlos, 2008-08-28)
A great deal of microbiological and genetic research in the pharmaceutical industry is directed towards the development of effective strategies in the handling of microorganisms
seeking the production of antibiotics that ...
Desenvolvimento de um pipeline para análise genômica e transcriptômica com base em Web services
(Universidade Federal de São Carlos, 2009-09-04)
Pipeline systems for genomic and transcriptomic analysis aim to create communication bridges among the existing analysis tools, therefore reducing researchers efforts. Most of the pipelines found in the literature lack ...
Isolamento, identificação fenogenotípica e potencial bioativo de microrganismos endofíticos intrinsecamente associados à Miconia albicans no Cerrado de São Carlos - SP
(Universidade Federal de São Carlos, 2009-09-03)
Endophytic microorganisms lives in symbiotic association with plants and in one unique biological niche, and they are potential producers of natural bioactive substances with different chemical structure and biological ...
Produção recombinante e estudos funcionais de uma cisteíno peptidase de Xanthomonas citri subspécie citri
(Universidade Federal de São Carlos, 2009-04-29)
The citrus canker disease is caused by a phytopathogenic bacterium Xanthomonas citri ssp. citri (Xac). The common symptoms are defoliation, twig die-back and premature fruit drop. The infection process of this bacterium ...
Estabelecimento de meios de cultura para o cultivo de Streptomyces isolados de sedimento marinho
(Universidade Federal de São Carlos, 2009-10-16)
Microorganisms represent an important source for production of bioactive metabolites for diverse applications. The production of these substances is directly related to the culture medium associated with sources of carbon ...