Navegando por Data de Publicação, começando com "2007-11-27"

Filtrar resultados por ano ou mês

Agora exibindo 1 - 4 de 4

Complexos carbonílicos de rutênio. De um gás tóxico a uma droga com potencial agente citotóxico
(Universidade Federal de São Carlos, 2007-11-27) Barbosa, Marília Imaculada Frazão; Batista, Alzir Azevedo; https://lattes.cnpq.br/6469642481998660; https://lattes.cnpq.br/4629917779644809
In this work ruthenium carbonyl complexes were synthesized and characterized which allowed an interesting spectroscopic and structural study as well as preliminary in vitro antitumor activity assays. Thus, the interests in the transition metal carbonyls, which carry and liberate CO, are also emerging as a pharmacological tool to mimic the bioactivity of endogenously generated CO. Therefore, this complex is being extensively studied for many applications in medicine. Starting from the cis-[RuCl2(dppb)(N-N)], N-N = bipy, Me-bipy, MeO-bipy, Cl-bipy, phen and bam, precursors, were obtained complexes with general formula ct-[RuCl(CO)(dppb)(N-N)]PF6 (P trans CO - series 1), for N-N = bipy and phen, starting from [Ru2Cl4(dppb)3], were obtained geometric isomers showing Cl trans CO - series 2 and for N-N = bipy was obtained the isomer with N trans CO - complex 9. Utilizing the mer-[RuCl3(dppb)(H2O] were obtained two isomers with general formula [RuCl2(CO)2(dppb)] (where the CO molecule is cis or trans positioned to P, labeled complexes 7 and 8 respectively. The formulations of compounds were proposed on the basis of the usual techniques: IV, NMR, X-ray and elemental analysis. The crystallographic and NMR 31P{1H} data showed a great influence of the ð acceptor CO ligand on the Ru-P distance and P chemical shift, respectively. The cyclic voltammogram showed high values for the oxidation of RuII/RuIII. The obtention of geometric isomers allowed the analyzes of the electronic influence of CO on the ligand trans. The cytotoxicity tests in tumor cells were performed with the three isomers of ct- [RuCl(CO)(dppb)(bipy)]PF6 with the aim to study the influence of the isomer type on the cell viability. Low values of IC50 were found, however no significative differences were observed among the ruthenium complex isomers. When compared with the metallodrug reference, cisplatin, these carbonyl ruthenium complexes showed lower value of IC50.
Mídia e beleza negra: a mulher negra em propagandas televisivas de produtos de higiene e beleza
(Universidade Federal de São Carlos, 2007-11-27) Gomes, Ana Paula Pereira; Silvério, Valter Roberto; https://lattes.cnpq.br/9421231847055027; https://lattes.cnpq.br/3605021512033683
This research addresses the representation of black women in television advertisements of hygiene and beauty products in Brazil in the early 2000s. The analysis sought to investigate the historical and sociological context of the emergence of Rexona Ebony, Vasenol (for "dark and black skin") and Seda for curly hair "chemically treated" and its advertisements. Given that they are products belonging to the multinational Unilever and that already existed in other versions, the dissertation sought to analyze which political and social factors influenced the market choice of brands in launching variations aimed at the black skin public at this specific moment, as well as to analyze how this phenomenon dialogues with the concept of black beauty; and how the media representation elaborated by these brands impacts the self-image of their consumers.
Determinação versus subjetividade: apropriação e ultrapassagem do estruturalismo pela psicanálise lacaniana
(Universidade Federal de São Carlos, 2007-11-27) Sales, Léa Silveira; Simanke, Richard Theisen; https://lattes.cnpq.br/5431145327759147
Dans la bibliographie concernant la psychanalyse lacanienne aussi bien que dans celle de l'histoire des idées en France dans la seconde moitié du XXème siècle, on trouve souvent l'indication de Jacques Lacan comme l une des figures les plus représentatives d'une certaine forme de penser que l'on a rétroactivement convenu de nommer "structuralisme" et dont les origines remontent aux recherches et propositions anthropologiques de Claude Lévi-Strauss. Tout d'abord, cette recherche essaie d'analyser non pas seulement la pertinence d'une telle indication, mais également les lignes de force et le mouvement théorique plus profond qui y sont impliqués. Autrement dit, elle pose initialement la question suivante: si Lacan a en effet subi une forte influence de l'anthropologie structurelle, à quoi, exactement, cela peut-il être imputé? Au champ psychanalytique, quelles sont les inquiétudes théoriques auxquelles la référence à la structure est supposée répondre? Comment a-t-elle été introduite dans une démarche qui avait déjà pris forme au sein de projets orientés vers la psychiatrie et la psychologie? Puis, le travail se tourne vers les tâches héritées de ce dialogue: il faut analyser les redescriptions lacaniennes de processus propres à la psychanalyse (OEdipe, psychose et désir, par exemple), ainsi que quelques thèmes philosophiques qui y sont liés, tels que les conceptions de vérité et de réalité et le problème de la présence d'une ontologie. La continuité de la recherche s'est imposée de par les résultats obtenus jusqu alors. Car dialoguer avec la structure exige, de la psychanalyse qui le fait, la rénovation de la pensée sur le sujet. La manière, déjà bien connue, dont elle s'en interroge apporte les termes suivants: dès que l'on assume que l'inconscient est structuré comme un langage, qu'est-ce que le sujet? C'est la confrontation jusqu'aux dernières conséquences à cette question qui, à son tour, contraint le psychanalyste à s acheminer vers un certain dépassement de la structure qui, naturellement, ne correspond pas à son abandon, mais à son ouverture, alors exprimée dans la notion de signifiant d'un manque dans l'Autre. On verra dans quel sens le surgissement, dans la théorie, de l'objet a opérateur central de la psychanalyse lacanienne n'est pas étranger à un tel parcours.
Caracterização e avaliação de filmes metálicos para uso em ultra-alto vácuo
(Universidade Federal de São Carlos, 2007-11-27) Ferreira, Marcelo Juni; Nascente, Pedro Augusto de Paula; https://lattes.cnpq.br/1387043320265189; https://lattes.cnpq.br/5471938976013160
The construction of ultra-high vacuum chambers (UHV) for particle accelerators demands pressure in the range of 10-8 Pa, and this is particularly difficult to achieve in chambers with the length to traverse section rate of approximately 150:1. Among several methods used to obtain this condition, it stands out the internal coating with metallic films capable of absorbing gases, called NEG (Non-Evaporable Getter). These metallic films, cannot have gas molecules on the surface and should be deposited on the internal surface of the chamber, making it a vacuum pump. Usually these materials are constituted by elements of great chemical reactivity and solubility (such as Ti, Zr and V), at room temperature for oxygen and other gases typically found in UHV (H2, CO and CO2), besides having low oxygen temperature diffusion (< 700 K), the so called activation temperature. The objective of this work is to characterize and to evaluate TiZrV alloy and Au films produced by magnet sputtering for UHV application. The structure, morphology and aging of the films have been characterized in order to know how much of the gas absorption property at low temperature can be attributed to the structure formed by the deposition process and the chemical reactivity of the elements. The morphological, structural and chemical characterization was carried out by atomic force microscopy (AFM), high resolution scanning electron microscopy (FEG-SEM), high resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Rutherford backscattering spectroscopy (RBS) and photon stimulated desorption (PSD). The produced materials were compared with commercial TiZrV samples, and this comparison made clear that the desired characteristics are related to the nanometric structure of the films and that the structure is clearly sensitive to the heat treatments.