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A flecha mata porque tem vida: um estudo etnográfico sobre os artefatos de caça dos Gavião Ikólóéhj
(Universidade Federal de São Carlos, 2013-10-08) Bento, Rodolpho Claret; Vander Velden, Felipe Ferreira; https://lattes.cnpq.br/7289231173735671; https://lattes.cnpq.br/3283988707462852
This work aims to elucidate the relationships the Gavião people of Rondônia engaged when manufacturing and using of hunting artefacts. From an ethnographic approach, I explore pertinent notions to comprehend the agency of warfare objects, hunters, dogs, and enunciations in hunting activity. I develop a parallel between the manufacturing of artefacts bodies and the constitution of artifactual anatomies of men, wishing problematize how encounters between bodies and materials (or substances) conforms the effectiveness of hunters and their hunting instruments. If into Gavião s discourse the arrow kills because has life , I propose to think what is that concept of vitality and the relationships produced about this assumption. It is a challenge outlined by a biographical study of the hunting artefacts, that is presented as an interlacement of vital forces in the interactions between humans, animals, spirits and objects.
Aplicando princípios de aprendizado de máquina na construção de um biocurador automático para o Gene Ontology (GO)
(Universidade Federal de São Carlos, 2013-10-08) Amaral, Laurence Rodrigues do; Hruschka Júnior, Estevam Rafael; https://lattes.cnpq.br/2097340857065853; https://lattes.cnpq.br/6978567037098928
Nowadays, the amount of biological data available by universities, hospitals and research centers has increased exponentially due the use of bioinformatics, with the development of methods and advanced computational tools, and high-throughput techniques. Due to this significant increase in the amount of available data, new strategies for capture, storage and analysis of data are necessary. In this scenario, a new research area is developing, called biocuration. The biocuration is becoming a fundamental part in the biological and biomedical research, and the main function is related with the structuration and organization of the biological information, making it readable and accessible to mens and computers. Seeking to support a fast and reliable understanding of new domains, different initiatives are being proposed, and the Gene Ontology (GO) is one of the main examples. The GO is one the main initiatives in bioinformatics, whose main goal is to standardize the representation of genes and their products, providing interconnections between species and databases. Thus, the main objective of this research is to propose a computational architecture that uses principles of never-ending learning to help biocurators in new GO classifications. Nowadays, this classification task is totally manual. The proposed architecture uses semi-supervised learning combining different classifiers used in the classification of new GO samples. In addition, this research also aims to build high-level knowledge in the form of simple IF-THEN rules and decision trees. The generated knowledge can be used by the GO biocurators in the search for important patterns present in the biological data, revealing concise and relevant information about the application domain.
Influência da síndrome da apneia obstrutiva do sono sobre os aspectos funcionais e inflamatórios de indivíduos com osteoartrite de joelho
(Universidade Federal de São Carlos, 2013-10-08) Mello, Andressa da Silva de; Rosa, Stela Márcia Mattiello Gonçalves; https://lattes.cnpq.br/1406279816228350; https://lattes.cnpq.br/7852712014105032
Introduction: Osteoarthritis (OA) is one of the major health problems and its prevalence has increased in recent decades as well, has been associated with sleep disturbances. It has been shown that chronic obstructive sleep apnea (OSA) is related to osteoarthritis, and sleep disturbances that may modify the physical and functional aspects of the disease. Objective: The aim of this study was to evalueted the influence of OSA on knee extensor torque, pain, stiffness, physical function, neuromuscular control and the inflammatory response in men with knee OA in early grades. Methods: The study included 60 male volunteers, aged between 40 and 70 years, divided into four groups: G1 (n=15): without OA and without OSA; G2 (n=15): without OA and with OSA; G3 (n=15): with OA and without OSA; G4 (n=15): with OA and with OSA. All volunteers were examined x-ray knee, polysomnography, responded to the WOMAC questionnaire and performed the test on the isokinetic dynamometer for evaluation of the peak knee extensor torque isometric (60º), concentric and eccentric (90°/s and 180º/s) and submaximal strength test, and blood was collected from the antecubital fossa for analysis of cytokines (IL-1β, IL-6, IL-10, TNF-α and TGF-β). Comparisons of means were performed using General Linear Model. Results: For data on the sleep pattern, volunteers showed differences between groups for stage 1, and the G2 and G4 showed a higher percentage of stage 1 when compared with the G1. The number of awakenings was higher in G4, which significantly differed from G1, and the same happened to differ from G1 to G2 . Regarding data WOMAC (pain, stiffness, physical function) can be observed that for all domains G4 showed higher values for the groups G1 and G2. For the knee extensor torque evaluations isometric and concentric isokinetic was observed at lower values compared to G4 and G2 with G1. However for the fluctuation of submaximal strength we found no difference between groups. In the analysis of inflammatory markers found reduced levels of TGF-β in G2 and G4 compared with G1, however for the other cytokines we found no difference between groups. Conclusion: We conclude that OSA influenced extensor torque isometric, concentric, in pain, stiffness, physical function and TGF-β, however, no influence on neuromuscular control and the other inflammatory markers (IL-1β, IL-6, IL-10 and TNF-α) in patients with OA in degrees initial, demonstrating that, as in the initial degree of OA the OSA may promote some inflammatory and functional changes in this population.