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A palavra do outro ouvida e respondida: uma compreensão enunciativa sobre a atividade de recontar histórias nas séries iniciais
(Universidade Federal de São Carlos, 2014-03-25)
Cardili, Wuendy Fernanda
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Brito, Maria Isabel de Moura
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https://lattes.cnpq.br/3337123452909799
On the assumption that a text is the guiding object for both teaching and learning, according to words by Geraldi (2003; 2010), the aim of this study is the analysis of written stories retold by students who are in process to become literate and focuses on how a otherness word becomes their own word in written production. Based on enunciative studies of language and on Bakhtin, it is assumed the idea of language as an interactive process and the constitution of the subject. The literacy is comprehended as a discursive process. Thus, the written language acquisition is considered from the relationship between subjects with, about and of the language. The corpus which permitted such analysis is formed by twenty four texts of middle school students from 2nd grade, written in 2010, based on the story Menina bonita do laço de fita by Ana Maria Machado. The genre retelling constitutes of an activity of retelling and happens to be from the perspective of counter-word of somebody else s discourse, in which the students written productions are the answer to somebody else s discourse.The paradigm of evidence, developed by Ginzburg (1986), is the methodological approach used to analyze the written productions and allows the comprehension of the singularity evidences related to written process. The association between the paradigm of evidence and the studies related to written acquisition allows the comprehension of the subject s dialogical relation processes and language. It was intended to develop a reflexive look at texts from the appropriation of the Otherness word. When in contact with other words, the subjects create their own words and by doing so build up meanings for the story. This creation process about language proves that retelling is not a reproduction, but the production of the new. The author s appropriation of words is assimilated to the subjects own words, in the new retold story, whose meeting the word, results in the production of a new text, a new, single and not-repeated enounced in enunciation chain. The retelling presupposes evaluation, comprehension and active and responsive activity in relation to somebody else s discourse. Thus, the dialogic relationship between some enounced, achieved through the activity of retelling reveals itself as an important strategy to produce meanings, in which the retelling allows a (re) signification of written work in school settings.
Saberes docentes: vozes de professores da infância sobre a educação matemática para crianças
(Universidade Federal de São Carlos, 2014-03-25)
Rocha, Maria José da Silva
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Sousa, Maria do Carmo de
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https://lattes.cnpq.br/6637658562543505
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https://lattes.cnpq.br/2658820524027100
The project objectives are to investigate the knowledge of three teachers from kindergarten, while in training in the context of Curriculum Activity of Integration, Education and Research (ACIEPE), Ludic Science for Kids: assumptions, activities and experiences . This activity was one of three actions that formed part of the Disclosure Project scientific playful Science for Kids: Workshops and outreach activities for Science, Mathematics and Technology for children from 3 to 6 years . This is a qualitative research and a Case Study, in which video recordings compose the methods of analysis and data collecting from an extension kindergarten teachers education course. It was conducted by the following question: What is the knowledge manifested by teachers from kindergarten, in the context of ACIEPE, for mathematical experiences of children aged three to six years, based on the cultural-historical perspective? The categories of knowledge developed by Tardif (2008) are the foundations of the analysis. Results indicate that in the context of continuing education teachers oral narratives are permeated by individual and collective knowledge that intertwine all the time, among them personal, those from school education prior to training for teaching as well as those from programs and textbooks. All of these different kinds of knowledge integrate knowledge of experience.
O êxodo cantado: a formação do caipira para a modernidade
(Universidade Federal de São Carlos, 2014-03-25)
Faustino, Jean Carlo
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Pellegrini, Tânia
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https://lattes.cnpq.br/0280434883580627
;
https://lattes.cnpq.br/9464988436162691
This thesis is dedicated to the understanding of the rural exodus in Brazil, from the analysis of modas de viola recorded by the duo Tião Carreiro and Pardinho throughout their career which corresponds to the decades in which happened the great demographic change that turned Brazil predominantly into an urban nation. The analysis is concentrated on the themes that reveal the encounter the Brazilian country culture with the modernity and the consequent endeavor of building the conciliation between the modernity and tradition, which it is trying to put itself into the new social and economic context incorporating new values and at the same time trying to preserve the essence of the Brazilian country cultural identity. From this effort, calls our attention on the lyrics, will arise, from one side, a meaning of the historical continuity resulting from the analogy between the challenges of the present and the past, on the other hand, an undisputed feeling of waste. Waste of material and immaterial goods that the narratives picture like a big epic movement of one people under formation trying to live in a new kind of society.
Produção de hidrogênio em reator anaeróbio de leito fluidizado a partir de glicerol bruto sob condições termofílicas
(Universidade Federal de São Carlos, 2014-03-25)
Ferreira, Janaína dos Santos
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Silva, Edson Luiz
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https://lattes.cnpq.br/2133864300816072
This study aimed to evaluate the influence of the hydraulic retention time (HRT) on hydrogen production using crude glycerol as a substrate in an anaerobic fluidized bed reactor (AFBR ) . The reactor had a volume of 1979 cm3, which was varied HDT in eight stages: Stage I, II, III, IV, V, VI , VII, VIII with HDT of 14, 12 , 10,8 , 6, 4 , 2 and 1 hour. The temperature was controlled at 55 °C, fixing the substrate concentration in the amount of 5 gL -1 . The inoculum used was granular sludge from the thermophilic anaerobic reactor and upflow sludge blanket ( UASB ) for the treatment of vinasse, located at Usina São Martinho , Pradópolis - SP . The results showed that the yield of hydrogen (HY) remained constant between the HDT of 2h to 14h (1.2 H2.mol glycerol and 1.4 mol -1) HRT of 1h and the yield was higher ( 3 moles H2 . glycerol mol -1). The volumetric H2 production was increased with decreasing HRT , with its maximum value of 1508.7 mL.h - 1.L - 1 in lower applied TDH (1h) . The biogas produced was composed of CO2 and H2. The composition varied with the decrease in HRT from 14 to 2h (Step IVII ) in the first seven stages (14 to 2 h ), reaching a mean rate between 50 and 60%. In the last phase, which HRT was 1h , the percentage of H2 biogas reached the maximum value of 70 % . The major metabolites obtained during the first seven stages of operation of the reactor were: Acetic acid (4.5 to 18%), butyric acid (4.3 to 21% ), ethanol (14 to 29%) and 1,3-propanediol (34 to 50%). As for 1h note the HDT of the presence of propionic acid (56%), acetic acid ( 11.5%) and 1,3- propanediol ( 30%).
Indicadores de sustentabilidade no contexto da Política Nacional de Resíduos Sólidos: uma proposta para Bragança Paulista-SP
(Universidade Federal de São Carlos, 2014-03-25)
Camargo, Isadora Vilela de
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Teixeira, Bernardo Arantes do Nascimento
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https://lattes.cnpq.br/1166854416745527
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https://lattes.cnpq.br/6516570337538739
Urban Solid Waste (USW) management represents an increasing challenge to municipal administration departments due to the growth in quantity of waste and complexity of its management. In Brazil, the National Solid Waste Policy (NSWP), approved in 2010, came to be a reference to local public policies, incorporating a concern with sustainability. Some authors have been proposing sustainability indicators (SI) to USW management since this sector needs tools to help with decision-making actions as well as with democratization of information to the society. However, these works neither consider the definitive content of NSWP, nor the strategic involvement of municipal councils related to the topic. This is important to assess how the conditions of these sustainability indicators match with the sustainability conditions brought by the policy. The aim of this present work was a proposition of a sustainability indicators set for solid waste management in Bragança Paulista-SP by means of consultation to the Municipal Environment Defense Council COMDEMA in the context of the NSWP. The research was based on interfaces assessment of three sets of SI for Solid Waste Management found in the literature with the NSWP. In order to facilitate this process, indicators were grouped in 15 topics, being detected their contribution and restrictions. This assessment, set on local context and researchers perceptions resulted in a proposal of a group of 25 SI which went through COMDEMA s consultation regarding relevance and form. On a second stage, new SI were developed, based on topics identified in the NSWP and were also consulted by the mentioned council. It was possible to ascertain that the NSWP incorporates dimensions of sustainability and many of its aspects are represented in the SI studied. This fact enforces the usefulness of this tool to a more sustainable solid waste management in local level. Nevertheless, to some recent topics such as reverse logistics, shared responsibility, Urban Solid Waste intermunicipal consortiums and recovery of organic solid waste, there were developed new indicators in order to get a more complete management. The final set resulted in 30 SI which meet the five dimensions of sustainability (environmental, social, economic, cultural and political) and include significant aspects of the NSWP as well as characteristic questions of the city. The involvement of COMDEMA, by its composition, engagement and interest, contributed to the access of information and members discussions, resulting in adjustments of the initial set, which include local demands. The experience of consultation adopted in this work, in order to propose SI to the SW management, can support future research, and may be adapted to the reality of other cities. The final SI set, which may come to be totally or partially incorporated to the Municipal Solid Waste Plan, can collaborate with execution of the NSWP in the city, leading it to a more democratic and sustainable management.
O salto do cinema brasileiro contemporâneo no céu do sertão: uma análise dos filmes O Céu de Suely e Viajo porque preciso, volto porque te amo
(Universidade Federal de São Carlos, 2014-03-25)
Santos, Márcia Vanessa Malcher dos
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Pellegrini, Tânia
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https://lattes.cnpq.br/0280434883580627
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https://lattes.cnpq.br/6004376537871160
The purpose of this research is to think about the representation of the sertão in contemporary Brazilian cinema , from the analysis of two recent films, O Céu de Suely (Karim Aïnouz, 2006) and Viajo porque preciso, volto porque te amo (Karim Aïnouz; Marcelo Gomes, 2010). To this end , we seek to understand the social implications of the sertão‟s denser moments in the national cinema, establishing a fundamental and necessary link between the present and the past. Furthermore, we investigated the relationship between cinema, state and market in the country in order to define the basis of current production and situate the place occupied by cinema from the Northeast in Cultural Industry, which comprises the filmmakers Karim Aïnouz and Marcelo Gomes . Finally, we turn to the chronotope concept of Mikhail Bakhtin, as analytical axis , to think about the dislocate‟s poetics, the remarkable presence of the road and nomadic individuals in the films analyzed. The aim is to map, dialectically, the forms of time and space in the narratives of O Céu de Suely and Viajo porque preciso, volto porque te amo and in the postmodern sociality of which they are part.
Competências do professor de Português Língua Estrangeira (PLE) em formação : (re)construção e reflexão
(Universidade Federal de São Carlos, 2014-03-26)
Negri, Marcia Fanti
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Viana, Nelson
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https://lattes.cnpq.br/6252579012192711
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https://lattes.cnpq.br/0126666263989130
This research aims to analyze the performance of teachers (in the process of education) of Portuguese as a foreign language, based on a range of theoretical models of competence. Therefore, a brief summary of the term competence was outlined, starting with the concept of communicative competence and their approaches related to foreign language teachers. This research is based upon theories of competence, communicative competence and competence for foreign language teachers. It includes the following authors teachers: Chomsky (1960), Hymes (1972), Savignon (1972), Widdowson (1978), Canale e Swain (1980), Canale (1983), Bachman (1990), Celce-Murcia et al (1995), as well as Perrenoud (1999), Basso (2001) and Almeida Filho (1993 e 1999). In order to collect data, the following instruments/procedures were used in this investigation: an initial questionnaire which aimed to obtain the teachers’ profile; audio recorded lessons; field notes and a final questionnaire. Afterwards, some criteria were established to analyze the data. Some excerpts of the recorded lessons were selected due to the fact that they show evidence of some competences. Based upon Almeida Filho (1993 e 1999) it is considered that the competences of foreign language teachers can be reconstructed through reflection upon their performance. With this work we aim to contribute to the process of reflection in teacher education in the field of foreign languages, as well as, to the literature regarding foreign language teaching and learning process and, more specifically, to the area of Portuguese as a Foreign Language teaching.
O carnaval de Antares: fantástico e carnavalização literária em Incidente em Antares
(Universidade Federal de São Carlos, 2014-03-26)
Silva, Valeria Cristina da
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Pellegrini, Tânia
;
https://lattes.cnpq.br/0280434883580627
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https://lattes.cnpq.br/2580476743625445
In extremely turbulent period corresponding to the decades of 1960-1970 in Brazil, literature has found curious ways. The authors of that period, trying to express the disjunction of Brazilian society, due to the military dictatorship, and aware of the inability to represent the world as a whole, found in the fragmentation of narrative and the use of other narrative resources - as cinema, advertising etc - an esthetic answer for such complex moment. In this scenario, however, stands the figure of Erico Verissimo, who chooses different ways. Respecting his own conception of literature, the author constructed a work averse to these esthetic renovations. Based on the pillars of "realism" Incidente em Antares innovates by introducing the supernatural element, well know by Todorov as "fantastic". Based on some studies related to fantastic literature and the historical moment, in which Incident em Antares was produced, our work has two specific objectives: first of all, to reveal how the fantastic element is articulated in the novel; secondly, to demonstrate how this fantastic element acquires specific characteristics, allowing the emergence of what Mikhail Bakhtin called literary carnivalization. Our main hypothesis is that the literary carnavalization in Incidente em Antares is responsible for its critical feature.
Caracterização morfológica e molecular de Campoletis Foerster, 1869 (Hymenoptera, Ichneumonidae, Campopleginae), parasitoides de Spodoptera frugiperda (Smith, 1797) (Lepidoptera, Noctuidae)
(Universidade Federal de São Carlos, 2014-03-26)
Camargo, Luiza Figueiredo
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Dias, Angélica Maria Penteado Martins
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https://lattes.cnpq.br/8637344058859147
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https://lattes.cnpq.br/7659288914273973
The fall armyworm Spodoptera frugiperda (SMITH, 1797) is a voracious pest of numerous crops of economic importance throughout the New World. In Brazil, their larvae can be attacked by several species of parasitic wasps, which are candidate to biological control agents against this pest. Surveying the parasitoid fauna on S. frugiperda in maize throughout Brazil two very morphological similar species of Campoletis are found. To ensure the efficiency of the biological control works, the knowledge about the taxonomy of the species related is necessary. Campoletis specimens emerged from Spodoptera frugiperda were studied mofologically and molecularly, in order to solve taxonomic problems among C. sonorensis (CAMERON, 1886) and C. flavicincta (ASHMEAD,1890). The samples came from three regions of Brazil: Santa Maria, RS; Ribeirão Preto, SP; Sete Lagoas, MG. Pictures from the type material of the two species were studied, besides the original descriptions of them. A possible sinonimy is indicated between the both species, for which the name C. sonorensis will be used based on the priority law for species names. A redescription is made to Campoletis sonorensis from Brazil, using morphological characters and DNA Barcoding.
Estudo da variação do perfil químico de citros com HLB e sadios, buscando informações sobre mecanismo de defesa
(Universidade Federal de São Carlos, 2014-03-26)
Bellete, Barbara Sayuri
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Silva, Maria Fátima das Graças Fernandes da
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https://lattes.cnpq.br/0457632122660653
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https://lattes.cnpq.br/5893633998701597
This paper describes the variation of the chemical profile study of citros after inoculation of the bacterium "Candidatus Liberibacter asiaticus", responsible for Huanglongbing (ex greening), one of the most serious diseases causing several losses in the Brazilian citrus industry. The bacterium "Ca. Liberibacter " was inoculated in seedlings of the" Valencia "(Citrus sinensis (L.) Osbeck) grafted on "Swingle" (Poncirus trifoliata x Citrus paradisi) and was evaluated the change of secondary metabolites by the development of analytical methods such as HPLC-UV, LC-MS/MS, LC-UVSPE- NMR and chemometric tools. The chemometric methods PCA and S-PLOT applied to data obtained in the studies by LC-MSE allowed to discriminate infected plants from healthy plants, and also allowed the characterization of the compounds that most contribute to this differentiation. By analyzing the change in the chemical profile of citrus studied by HPLC-UV-SPE-NMR, it was able to detect the change of some coumarins in the roots and stem from rootstock, and glycosides flavonoid in leaves, indicating that these compounds may be involved in defense mechanism of the plant, and may be acting as a Phytoanticipins. Aiming to better interpret this change observed, also performed a quantitative variation of some secondary metabolites, as coumarin identified in the roots, and flavonoids identified in leaves. This technique showed an increase of coumarins in infected plants, while there was a decrease in all the flavonoids in the leaves in infected treatment, indicating that the plant defense is in the roots. Finally, a phytochemical study of citrus was performed aiming obtain patterns compounds, and this study resulted in the isolation of 13 substances, from several classes of secondary metabolites.
Participação social e estratégia saúde da família : desvelando fragilidades e possibilidades
(Universidade Federal de São Carlos, 2014-03-26)
Furlanetto, Camila Fressatti
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Ogata, Márcia Niituma
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https://lattes.cnpq.br/3274294833403570
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Machado, Maria Lúcia Teixeira
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https://lattes.cnpq.br/5703683100332513
The participation and the social control are guiding principles of SUS and for democratization of the system. The health acting and services management should express joint definitions between the government and population. The 8.142/1990 Law establishes as instances for participation and social control in the Health the counsels and the conferences. The Family Health Strategy (FHS) could be considered an easier locus of the materialization of the social participation because of the link possibility with the user population. Considering this hypothesis, the research sought to analyze the users and Health worker’s perceptions of the Family for the social participation, seeking for the social effective control in health. It was held with workers and users of two Family Health Units in the São Carlos county, from the qualitative analysis, up with the application of semi structured interviews and thematic analysis, whose origins three categories(i) challenges for the effectiveness of the social participation in the FHS; (ii) participation spaces or just completion of formalities?; (iii) FHS: potentiality for social participation. The results of this study allowed unveiling various fragilities that figures as challenges for the social participation in the researching field, such as: lack of information/comprehension, exposition and power relations and welfares/accommodation. The institutionalized spaces for the participation and social control addressed in this study were the Municipal Health Conferences and the locals Management Councils, the effectiveness of them were analyzed negatively due lack of support and government participation. The research allowed unveiling also potentials as the counsels’ effort and the capacity spaces done between the team and the users members of the Management Councils in the Family Heath Units. Lastly, the participants perception strengthens the challenge that is the social participation in the SUS. As contribution, the needing pointing of more investment and attention to this spaces from the recognition of their potentialities.
Catalisadores à base de Cu, Zn, Al e Ce aplicados à reação deslocamento gás-água
(Universidade Federal de São Carlos, 2014-03-26)
Borges, Laís Reis
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Assaf, José Mansur
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https://lattes.cnpq.br/9563312407691130
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https://lattes.cnpq.br/9219091363286049
The water gas-shift reaction (WGS) is an important step in the production process and purification of H2 from hydrocarbon. Commercially, to overcome the thermodynamic and kinetic limitations, this reaction occurs in two steps, one at higher temperature (450º C to 320ºC) and another step at lower temperature (190º C to 250ºC). The catalyst Cu/ZnO/Al2O3 is used industrially for water gas-shift reaction at low temperature in the chemical and petrochemical industry. Although widely used, are disagreements about the role of each metal in the catalyst, the role of Zn and Al as promoter or stabilizer is not clear and controversies about the influence of some parameters in the activity. This study verified the activity of the catalyst Cu/ZnO/Al2O3 in water gas-shift reaction in the range of temperature, 150ºC to 350ºC, and the feed molar ratio of CO: H2 equal to 1:5. The catalysts were prepared by co-precipitation method, and the effects of content of Al, ratio Cu/Zn and the CeO2 addition was investigated. There was a synergistic effect between the metals Cu-Zn-Al at a ratio (6:3:1), which led to a larger surface area of Cu metallic, and a higher activity compared to the catalysts bimetallics: CuAl (6:1) and CuZn (6:1). By adding Ce to the tri-metallic compound a greater activity was observed at higher temperature than 250ºC, caused by the activation of the effect of oxygen storage characteristic of cerium oxide, however it has been a reduction on stability. The quantity of Al influenced the precursor structure whith formation of rosasita and malachite with low levels of Al, and hydrotalcite structure was observed when the Al content was higher than 11.4% (mass concentration). A great quantity of Al (16% (mass concentration)) was found among the hydrotalcite catalysts, which led to a higher conversion of CO and higher crystallinity, however this activity is almost the same of the catalyst derived from the structures malachite and rosasita (CuZnAl/6:3:1) at high temperature. The catalyst whith Cu/Zn=2 presented higher activity at temperatures below 250ºC, probably due to the higher metallic area, while at high temperature, catalysts with high ratios of Cu/Zn achieved higher conversions. Therefore, this study verifies that TOF (turn over frequency) isn t directly related with surface area of Cu0, the crystallinity and quantity of Cu are factors that influenced the activity of the WGS reaction.
Integração e segurança na Amazônia transnacional
(Universidade Federal de São Carlos, 2014-03-26)
Correa, Paulo Gustavo Pellegrino
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Martins Filho, João Roberto
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https://lattes.cnpq.br/4935704081469903
This study aims to understand the dynamics of integration and security in the transnational Amazon and its importance to South America and also it analyzes the role of Brazil as the largest amazon country in the binomial integration/ security in the region . The theoretical approach adopted by this research is called the " Copenhagen School " which is based on three analytical pillars : the concept of securitization and desecuritização , multisectoral approach to security and the concept of regional security complexes . Our time frame is concentrated between 2000 - the date of the first summit of South American countries where major integration initiatives have been launched - and 2013 , the year of completion of our research . Since the Amazon region covers more than 50 % of the South American subcontinent and involves nine countries , it is possible to identify axes of countries that comprise different dynamics in the binomial integration / security. Considering the importance of this dynamic to Brazil , we will highlight our work on two axes within the transnational Amazon : Peru - Brazil - Bolivia and the Guiana Plateau axis. The first stands out for having an integration process that brings Brazil to the Pacific and presents a specific secutity constellation within the transnational Amazon . The second represents the path of integration between Brazil and northern of the subcontinent and the Caribbean and also demonstrates a specific regional security dynamics in Amazon region.
Estratégia competitiva e estratégia de produção: estudos de caso na produção de embalagens obtidas a partir de polietileno proveniente de fontes sucroalcooleiras
(Universidade Federal de São Carlos, 2014-03-27)
Motta, Gabriela Azevedo
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Alves Filho, Alceu Gomes
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https://lattes.cnpq.br/7885557554922569
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https://lattes.cnpq.br/7250712374641353
In the search for new positions in the market, many companies have sought to differentiate their products and services, possibly reformulating their strategies. One of the possible strategies for modification is related to sustainability of the materials used in products and processes, such as plastic from sugarcane sources. The objective of this work is tried to identify the competitive strategies and manufacturing strategies adopted by companies that use plastic from sugarcane in package. To achieve this objective was opted for conducting case studies of two companies leader in their segments: a producer for the staffing industry, perfumery and cosmetics and other packaging supplier to the food industry. The first company competes with a focus on differentiation in only one segment, and its manufacturing strategy of horizontal integration of its packaging. The second company adopts a competitive strategy of differentiation in the context of the industry, and a manufacturing strategy of vertical integration of its products.
Aprender a aprender: uma trajetória possível para os trabalhadores do SUS?
(Universidade Federal de São Carlos, 2014-03-27)
Costa, Ana Clara Lopes
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Lima, Valéria Vernaschi
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https://lattes.cnpq.br/7945420582384290
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https://lattes.cnpq.br/2140918293527948
The main goal in this study is to analyze the learning process of the Brazilian Unified Health System (SUS) staff when exposed to an interactionist educational initiative. Such initiative aims the transformation of health practices by focusing on clinical management and qualifying care for the users of SUS in 33 hospitals from the 5 Brazilian geographical regions. This study used a specialization course that was developed in 2009-10 that focused on the articulated development of management abilities, support and education in health. The study was based on the principles of qualitative research and the completion of course work drawn by the attendees of the specialization course on Clinical Management was also used as a source of data. The content was analyzed for data interpretation aiming to identify and explain the causes and interactions for the production of the phenomenon. The novelty of the proposal was not an obstacle for the learning process. Student focused learning and the appreciation of previous knowledge where related to the practical application of such content and the broaden of autonomy, especially on what concerns recently acquired information. It was also observed that the participants actions were related to the three areas: clinical management; health awareness and education. The interaction in small groups, communication, integration and open dialogue were valued as fundamental e facilitating elements of learning, group work development and qualification of care. Transformation on practices on health related to management, attention and education were observed and were part of the knowledge that define the profile of clinical management built and developed through the course.
Efeitos do exercício intervalado na expressão de proteínas inflamatórias e catabólicas na musculatura esquelética de ratos tratados com dexametasona
(Universidade Federal de São Carlos, 2014-03-27)
Martuscelli, Aline Mio
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Cardoso, Sandra Lia do Amaral
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https://lattes.cnpq.br/2030708742766455
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https://lattes.cnpq.br/3580215119041185
Dexamethasone is widely used in clinical use due to its potent anti-allergic and antiinflammatory effects, but it has been shown that its chronic use can induce several side effects such as hyperglycemia, hypertension, hypercholesterolemia and muscle atrophy. Muscle atrophy occurs by an imbalance between catabolic and anabolic protein levels. Among catabolic proteins, FOXO3a, MuRF-1 and Atrogin-1 are directly related to muscle atrophy induced by dexamethasone. Furthermore, it is known that some inflammatory proteins (TNF-α and IL-6) also participate in reduction of muscle weight. We have shown that aerobic exercise attenuates some of the side effects of dexamethasone, but nothing is known about interval training (IT) performed before and concomitant dexamethasone treatment. This study investigated if interval training is effective in attenuating muscle atrophy induced by dexamethasone and if the proteins FOXO3a, MuRF-1, Atrogina-1, TNF-αand IL-6 are involved in this response. Rats were distributed into 4 groups: sedentary control (SC), sedentary + Dexa (SD), trained control (TC), and trained + Dexa (TD), and underwent an interval training period (50% and 80% of maximal capacity, 2 and 1 min, respectively, 1h/day, 5 days / week, 70 days) or remained sedentary. Dexamethasone was administered during the last 10 days (0.5mg/kg per day i.p.). The rats were weighed weekly during training and daily during the treatment. The tibialis anterior (TA), soleus (SOL) and flexor hallucis longus (FHL) were collected, weighed and stored for analysis of TNF-α, IL-6, FOXO3a, MuRF-1 and Atrogin-1protein levels using electrophoresis method, Western Blotting. Administration of dexamethasone resulted in a significant decrease in body weight (-17%) followed by reduction in TA (-22%) and FHL (-19%) muscles weight. This reduction in muscle weight involved a significant increase in MuRF-1 protein levels in TA (+27%) and FHL (+18%) muscles, although TNF-α (-37%FHL and -15% SOL) and IL-6 (-26% TA, - 24% FHL and -18% SOL) protein levels were reduced. Interval training was effective in blocking the increase of MuRF-1protein level in TA and FHL muscles, moreover interval training significantly reduced FOXO3a production level in TA muscle, in both groups, TC (-27%) and TD (-32%).This response was followed by an attenuation of TA muscle mass after training. Chronic treatment with dexamethasone, as well as training, did not change Atrogin-1protein level. The results of the present study allow us to conclude that MuRF-1 seems to be involved in TA and FHL muscle atrophy induced by dexamethasone treatment, independent of inflammatory proteins signaling. On the other side, interval training determined TA muscle atrophy attenuation by decreasing MuRF-1 and FOXO3a without changes in TNF-α e IL-6 protein levels.
Biotransformação de cicloadutos de Diels-Alder por células intactas de Penicillium brasilianum, endofítico de Melia azedarach
(Universidade Federal de São Carlos, 2014-03-27)
Santos, Ana Carolina Alves dos
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Rodrigues Filho, Edson
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https://lattes.cnpq.br/3667941735597178
;
https://lattes.cnpq.br/6169045230374129
Endophytic microorganisms have a great enzymatic potential to biotransformate substances of natural and synthetic origin due to strategies developed during colonization to coexist with the plant in an initial hostile environment. Microbial transformation of Diels-Alder cycloadducts were trailed by the endophyte P. brasilianum using intact cells and resulted in the production of several products (17). These products were identified as products of chlorination (Q4_F2_15), epoxidation (Q1A_CR_16, Q2A_CR_6, Q3A_CR_5), epoxidation and reduction of conjugated double bond (Q2A_CR_5), reduction of conjugated double bond (Q2A_CR_9, Q3A_CR_7_pico2, Q3A_CR_8, Q4A_CR_23), reduction of isolated double bond (Q1A_CR_26), oxidation of allilic methyl group and reduction of conjugated double bond (Q4A_CR_10), reduction of carbonyl and conjugated double bond (Q4A_CR_20), reduction of carbonyl and ether formation (Q5A_CR_15) and finally, reduction of carbonyl group (Q4A_CR_15 e Q5A_CR_18). The reduction of conjugated double bond can be performed by enzymes called Old Yellow Enzymes (OYE), also known as enoate reductase enzymes. The products of carbonilic or double bond reduction were also synthesized chemically and the enantioselectivity of both in vitro and in vivo process were compared. In all cases, microbiological transformations were more enantioselectivity.
O uso de instrumentos de análise ergonômica no processo de trabalho agrícola: o caso da colheita mecanizada da cana-de-açúcar
(Universidade Federal de São Carlos, 2014-03-27)
Ferreira, Ana Lucy Rodrigues
;
Alves, Francisco José da Costa
;
https://lattes.cnpq.br/9183120186518337
;
https://lattes.cnpq.br/1604837309190395
The changing in the labor dynamics of the sugarcane harvesting, occasioned by integration of mechanical harvesters, has subjected workers to new working conditions, increasing the interactions with machines, and consequently causing new diseases and work accidents. For improving the performance of work so that this becomes less destructive of human capabilities, is important the use of instruments that allow the identification of risks from man-labor ratio, which are identified through the study of literature in Ergonomics. This study aimed to verify the applicability of the checkpoints of the instrument Ergonomic Checkpoints in Agriculture to the work situation in the context of mechanized harvesting of cane sugar. A review of the relevant issues related to the study was accomplished, considering the themes: Ergonomics, ergonomic analysis tools and working conditions; process of mechanized production of cane sugar, with a focus on the process of harvesting and working conditions; and, finally, the study of the instrument Ergonomic Checkpoints in Agriculture. Subsequently, the analysis of the instrument was accomplished, which was constituted of the following principal stages. Initially, the checkpoints of the instrument were classified considering the workloads, and the similarity of content. Posteriorly, the checkpoints were analysed with respect the applicability in the job functions found in mechanical harvesting of cane sugar process. As a result, 84 checkpoints were classified into 23 clusters and 16 checkpoints were not grouped, among which 11 clusters and 8 checkpoints, which represent 53% of the content of the instrument, were identified with potential of application in the sugarcane mechanical harvesting. The checkpoints identified may assist in the evaluation and implementation of better working conditions, considering the ergonomic point of view, in the mechanical harvesting of sugarcane.
Os ensinamentos de Confúcio e a formação contemporânea de professores de língua inglesa em Taiwan : relações entre variáveis socioculturais e competências
(Universidade Federal de São Carlos, 2014-03-27)
Tsai, Yun Hsien
;
Viana, Nelson
;
https://lattes.cnpq.br/6252579012192711
;
https://lattes.cnpq.br/5857492244010306
This work aims to study the profile of English teacher education in Taiwan through a more specific discussion of language teacher’s competence. For this, we chose to analyze an English undergraduate teacher education program at a public university in this country, and, considering time constraints, we limit the study, focusing on the perspective of the teacher educators. Therefore, the program curriculum and the transcriptions of interview with the teachers educators will comprise the data set for analysis. Once teacher education process is based on the social system of the country, we also include the contextual factors or socio-historical elements in the study, by considering them as constituents of social constructions factors.
Identificação de regiões genômicas e genes candidatos associados com qualidade de carne e conteúdo de minerais no músculo em bovinos da raça Nelore
(Universidade Federal de São Carlos, 2014-03-27)
Tizioto, Polyana Cristine
;
Regitano, Luciana Correia de Almeida
;
https://lattes.cnpq.br/4754030540306395
This thesis is divided into three chapters in order to facilitate the understanding of the experiments that will be presented. The first chapter refers to a concise literature review, which covers the main theoretical themes and justifications regarding the developed experiments presented in the following chapters. The second chapter presents two genome-wide association studies in Nellore cattle, being the first for meat quality traits and the second for the mineral content of the Longissimus dorsi muscle. Considering the importance of beef tenderness for producer, the third chapter deals with the strategy used to identify candidate genes that explain the variation in this trait in Nellore breed. The experimental results suggested that meat quality traits and mineral content of skeletal muscle is at least partially genetically determined. Most quantitative trait loci (QTLs) identified is of small effects, revealing the polygenic background of those traits and the importance of applications that consider variation at the genomic level. However, some major effect QTLs were found for muscle pH , iron, selenium , zinc and calcium content in muscle, which accounted for 4.01 , 6.53 , 3.53 , 2.59 and 2.55% of the additive genetic variance , respectively. Through these studies, we produced an extensive list of candidates genes and metabolic pathways related to economic interest traits in beef cattle, which should contribute to the understanding of the their underlying genetic mechanisms. A genome-wide association approach still not economically feasible for beef producers, therefore candidate genes strategy is interesting because of its major accessibility. KCNJ11, MyoD1 and ASAP1 candidate genes were identified as explaining part of the variation in meat tenderness of Nellore breed. The validation of genomic regions and candidate genes identified in this study and future mapping of causal mutations should contribute to the implementation of marker-assisted selection and for the genomic selection of traits of economic interest in Nellore cattle.