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Estratégias de enfrentamento no processo de aconselhamento genético em situações de deficiência intelectual grave ou profunda: um estudo clínico-qualitativo
(Universidade Federal de São Carlos, 2019-02-08)
Carvalho, Ellen Zapparoli Nunes de
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Melo, Débora Gusmão
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https://lattes.cnpq.br/2587800992546559
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https://lattes.cnpq.br/8410205577252633
Introduction: Coping strategies are techniques used by individuals to adapt to challenging situations and are traditionally classified as problem-focused, emotion-focused, interpersonal coping strategies, or based on spirituality/religiosity. Parents who have children with intellectual disability (ID) experience ambiguous feelings and the coping strategies used by them will indicate the meaning of their experiences. The characterization and understanding of these coping strategies can be useful in clinical interventions and in the planning of public health policies. Aims: This research investigated the coping strategies used by mothers of patients with severe or profound ID during the genetic counseling process. Methodology: This is a clinical-qualitative study carry out with 15 mothers of patients with severe or profound ID, selected by convenience. Data were collected through semi-structured individual interviews. The reports were recorded, transcribed and investigated by the thematic content analysis technique. The results were examined through a comprehensive and interpretative approach. Results: There was a predominance of problem-focused and interpersonal coping strategies that were combined with emotion-focused and spiritual/religious coping strategies. Mothers’ adaptation varied with the stressful events to which they were exposed to and depended on the different degrees of individual tolerance to adverse situations. The higher frequency of problem-focused and interpersonal coping strategies suggested that mothers assessed the situation as likely to be modified and sought institutional and social support to facilitate adaptation to the child's needs and consequently improved their way of life. In general, the religious/spiritual coping strategies were associated with positive outcomes, facilitating the adjustment to the situation. Conclusions: It is necessary to improve external adverse situations by providing adequate support services, especially health services and specific support to the disabled to promote the development of positive coping strategies. Providing orientation on ID and building a comprehensive network of community services and supports are other important factors in coping.
Investigação do tratamento com N-acetilcisteína nos comportamentos relacionados à ansiedade durante a síndrome de abstinência do etanol e na resposta cardiovascular induzida pelo estresse em ratos
(Universidade Federal de São Carlos, 2019-02-08)
Casula, Lígia Cury
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Crestani, Carlos Cesar
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https://lattes.cnpq.br/1117432571971568
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Marin, Marcelo Tadeu
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https://lattes.cnpq.br/7920438802539727
N-acetylcysteine (NAC) for decades, has been shown to have beneficial effects for the treatment of some diseases. Recently, based on central glutamatergic neurotransmission, psychiatric disorders and the stress response have been explored.Ethanol addiction and cardiovascular and autonomic changes in the exposure of stress are considered public health problems and responsible for a large number of deaths in the world.Both problems are related to dysfunctions in central glutamatergic neurotransmission. Thus, our first objective was to investigate whether NAC was able to reverse one of the negative emotional states of the ethanol withdrawal syndrome, anxiety. For this, Wistar rats were induced to anxiety-related behaviors in the Elevated Plus Maze (EPM) after withdrawing the treatment of ethanol offered in their drinking fountains and intraperitoneal injections of ethanol (2 g / kg) for 11 days. During ethanol exposure, the animals also received 10-day intraperitoneal injections of NAC at doses of 30; 60 and 120 mg / kg and on day 11, on the day of the EPM test, the animals did not draw NAC or only received a single injection of NAC 2 hours before the EPM test. Ethanol concentrations in blood were also checked to analyze ethanol pharmacokinetic changes and the best time to investigate withdrawal symptoms. The second objective of the study investigated the effects of NAC on the possible reversal of cardiovascular parameters altered by exposure of the stress of repeated or acute restriction. The results showed that NAC was not able to revert anxiety-related behaviors after treatment withdrawal with ethanol. The NAC also did not reverse the cardiovascular changes induced by restriction stress such as blood pressure, heart rate and tail temperature. However, in the response of the baroreflexs, the NAC presented a potential effect in altering the their sensitivity. Acutely 2 hours before analysis of baroreflex functions, NAC reduced tachycardia. After 24 hours of its acute administration and after its chronic administration, NAC presented bradyadic increase and reduction of intrinsic heart rate in normotensive animals. When associated with stress exposure reduced sympathetic tone, increased intrinsic heart rate and reduced bradycardic function. Therefore, its use requires caution, due to changes in the cardiac requencia and changes in baroreflex sensitivity.
Combinação de reações organocatalíticas e multicomponentes para a síntese de sistemas heterocíclicos e moleculas híbridas
(Universidade Federal de São Carlos, 2019-02-08)
Pérez, Radell Echemendía
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García Rivera, Daniel
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https://lattes.cnpq.br/2938011588420423
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Paixão, Márcio Weber
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https://lattes.cnpq.br/3773908504964104
Small enantiomerically pure or enriched organic molecules are key starting materials in organic synthesis. Chiral building blocks are in high demand in the overall synthesis of complex natural products and in the discovery and development of drugs as well as in the production of advanced pesticides, fragrances and materials. In this sense, organocatalytic methodologies have emerged as a third pillar of asymmetric catalysis and have a prominent position in the development of more sustainable methods. Similarly, multicomponent reactions (MCRs) present themselves as a powerful tool for the synthesis of bioactive heterocyclic compounds and analogues of natural products. Chiral aldehydes are key components in stereocontrolled MCRs, methods for the asymmetric functionalization of carbonyl compounds are relevant for the development of novel multicomponent stereoselective approaches. In recent years, our group and the Banfi group have been exploring the potential of organocatalysis to generate compounds enantiomerically enriched with the synthetic power of MCRs in the diversification of these chiral compounds. In this work we describe a highly stereoselective methodology for the synthesis of natural product hybrids from an organocatalytic tandem procedure, followed by a multicomponent reaction. Effectively, the procedure comprises an organocatalysed conjugate addition of active methylene compounds (1,3-dicarbonyls and α ester or cyanoketones) to α,β-unsaturated aldehydes to form asymmetric hemiacetals containing orthogonal functional groups. Next, an isocyanate based intramolecular multicomponent reaction is implemented. Through the use of this approach it was possible to synthesize hybrids of natural products, including up to four different molecular fragments, such as hydroquinoline, tetrahydropyridine, peptides, lipid and glycoside units
“Aqui não é um paraíso, mas é muito bom”: imersão e identidade de jovens africanos francófonos aprendizes de português no Distrito Federal
(Universidade Federal de São Carlos, 2019-02-08)
Cañas Chávez, Fidel Armando
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Barbosa, Lúcia Maria de Assunção
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https://lattes.cnpq.br/5030878430187815
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https://lattes.cnpq.br/1406833402007752
Language, identity and learner were not always closely related concepts. During the years of the tradition of the structuralism, in the second half of the twentieth century, there was a separation of these concepts, making them independent, systematizable and stable. This thesis aimed to follow the theoretical flow of poststructuralist thinking in the indissoluble relationship between identity, language, learning and individuals who learn and put themselves in active process. I focused epistemologically on the field of Applied Linguistics, as a phenomenological area that gave fundamental support to the present thesis, which aimed to understand the process of identity construction of learners of Portuguese as a foreign language of a group of 23 young Francophone Africans who came to Brazil in the year 2017 to take an immersion course within the framework of the Programa de Estudante Convênio de Graduação (conventionally called as pre-PEC-G). Methodologically, the research was characterized as a case study, and the elements of data collection were the recordings of the interviews of three simulated Portuguese Proficiency Certificate for Foreigners (Celpe-Bras) conducted throughout the school year, and dense participant observation as well. The analysis was made through the stories or narratives that the youngsters verbalized about their experience in Brazil. The objective of the research was to understand how young people subjectively position themselves to narrate their processes of identity construction as learners of Portuguese in Brazil. This construction process was analyzed as a place of struggle engaged in diverse communities of practice with acts of resistance and non-participation that generated ambivalences and contradictions in the apprentices and I observed a construction of identity that was also influenced by the imagined communities that the young people previously owned and raised in Brazil. Finally, it was analyzed how the social imaginary had repercussions in the identification of the young apprentices in immersion condition in Brazil. The research also aimed to contribute as a reading to reflect on the learning processes of foreign languages, under the poststructuralist theories of the construction of identities, in order to fit the theoretical ground of Brazilian researches that embrace the teaching and learning of Brazilian Portuguese as second language or foreign language.
Análise do comportamento de filopatria e dispersão em felinos, com ênfase em Puma concolor com o uso de ferramentas moleculares
(Universidade Federal de São Carlos, 2019-02-08)
Oliveira, Marina Elisa de
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Galetti Júnior, Pedro Manoel
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https://lattes.cnpq.br/7398754661670478
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https://lattes.cnpq.br/3652140758600140
Among species of polygamous mammal it is expected that almost all males will disperse, acting as the main responsible for the connectivity between populations; on the other hand, females will show greater tendency to philopatry and will be responsible for the stability and local population growth. This behavioral asymmetry results in greater kinship among females than among males in the same area. However, anthropic interferences may alter species behavior and affect the persistence of populations. In order to understand better the occurrence and causes of sex-biased philopatry in felines, we first conducted a systematic literature review on the subject and subsequently a case study of Puma concolor through molecular tools. We found the pattern described for polygamous mammals for most of the species included in the review, except for three species of the genus Lynx. As expected, anthropogenic influences (hunting, habitat fragmentation, and the existence of barriers, mainly roads) can alter the patterns of philopatry and dispersal. The observed behavioral variation between populations and species seems to be due to the context in which the population is inserted (anthropic and natural variables) and the behavioral plasticity of each species. Populations were studied mainly with radiotelemetry and molecular tools, however we detected that few studies are comparable between species and even between populations of the same species. A more detailed description of the study areas could facilitate comparison between studies, at least in relation to the context the population is inserted. Regarding the species P. concolor, studies consistently point to greater male dispersal and female philopatry. Through the noninvasive sampling (feces) of individuals within conservation units, in a fragmented area and in a continuous area, as well as the sampling of roadkilled individuals, we were able to delineate patterns of intrasexual kinship in each sampling scheme. The highest mean values of kinship were observed between males and between females of the fragmented area, indicating greater female philopatry and probable frustrated male dispersal due to fragmentation and the existence of roads as barriers. More males than females were sampled as roadkills, corroborating greater male dispersal tendency and consequent mortality. This is the first evidence of frustrated dispersal in a Brazilian population, also demonstrating the potential of genetic analysis and non-invasive sampling for the study of population dynamics.
Terapia ocupacional e cultura: uma curadoria de tessituras entre práticas, políticas, diversidade e direitos
(Universidade Federal de São Carlos, 2019-02-08)
Silvestrini, Marina Sanches
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Silva, Carla Regina
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https://lattes.cnpq.br/6417501858864106
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https://lattes.cnpq.br/0814604765887538
El enfrentamiento y los desafíos de la inclusión, derecho, ciudadanía y diversidad cultural se expresan como campo de lucha conceptual, académico, político y cultural inmersos en la sociedad contemporánea gobernada por la racionalidad neoliberal. Esta investigación comprende la cultura como un campo de saberes y prácticas propios, el derecho a la cultura como fundamental en respeto por la diversidad humana y ampliación de las potencias de las personas y para el desarrollo de las comunidades. Así como, considera la Terapia Ocupacional en la cultura como campo de saberes y haceres plural, innovador y que se propone al cuidado de sujetos y colectivos, en las diversas dimensiones de la existencia humana, para el fortalecimiento de la libertad cultural, universalidad de las oportunidades y enfrentamiento de los procesos de exclusión y desigualdades. De esa manera, la investigación ha producido una curaduría ética-estética y sensible con el objetivo general de analizar los procesos y prácticas de Terapeutas Ocupacionales en el campo de la cultura, a partir de la política nacional de los “Puntos de Cultura” del Programa Nacional de Cultura Viva. Se intentó discutir y trazar conexiones entre las dimensiones de la cultura, los preceptos de las políticas públicas culturales y la Terapia Ocupacional. Los procedimientos metodológicos fueron estructurados en realizar estado del arte, entrevistas semiestructuradas y narrativas confeccionadas por los participantes, desde cuatro escenarios de prácticas en el campo de la cultura. La investigación presenta conexiones entre conceptos claves de la Terapia Ocupacional y de la Cultura: actividad humana, cotidiana, ocupación, diversidad, prácticas en terapia ocupacional, compromiso ético político y defensa por los derechos. El campo de la cultura en composición con la Terapia Ocupacional se mostró como un camino vivo, pulsante y en construcción, en el cual las prácticas del trabajo fueron consideradas como comprometidas y críticas. Esta investigación intentó identificar e iluminar aspectos importantes de trayectorias y prácticas de la Terapia Ocupacional en la cultura, como por ejemplo las tesituras descubiertas y las relaciones explotadas entre la cultura y la diversidad, la cultura como derecho fundamental y como campo vasto se entrelaza con las actividades, acciones y ocupaciones de la existencia humana, por lo tanto, pasible de construcciones y producciones que valoran la potencia de la vida.
Rodas de conversa no projeto "Vivências em atividades diversificadas de lazer": sistematização de experiências e processos educativos
(Universidade Federal de São Carlos, 2019-02-08)
Fábis, Lúcio de Castro
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Gonçalves Junior, Luiz
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https://lattes.cnpq.br/1324174147128430
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https://lattes.cnpq.br/3038033302607831
This work is inserted in the research line of Social Practices and Educational Process, lined on the referential frame of Epistemologies of the South, especially towards praxis of leisure, humanization and the “dialogicity” by Paulo Freire. Has as its central objective, identify, describe and comprehend the educative process that arising from the conversation circles in the context of the extension project “Living In Diversified Leisure Activities” (VADL) with children and teenagers. Based on the Experiences Systematization, methodology designed within the Latin American popular education. Intend, in this sense, to contribute for a construction and reconstruction collective practical-theoretic of these conversation circles, apprehending the formative, educative and social value, and specifics of this experience, susceptible to replications in other spaces and contexts. In analysis by phenomenological inspiration, by registrations collectively constructed, mainly by field diaries, supported by voice/video recording, emerged the following thematic categories: A) “Somebody knows the colour of the skin of God?”: alterity and diversity, adding to educational process related to the development of alterity by the contact with the diversity, the exchange of experiences and backgrounds on/by the circles, contributing to “being getting” trough prejudices and expanding comprehensions and world readings; and B) “The beauty of the combinations is that do not personify ": participation and cooperation, in the face of educational processes related to “co-laboring” in the experiences, constructed collectively and continuously through planning, reflections and evaluations and self-evaluations of activities and attitudes, including in relation to the procedures of the present research, in order to develop the autonomy and the protagonism of subjects, as well as the incessant search for coherence. In the end, projections of continuities and communications to contribute with the systematized experience itself, with the construction and valorization of the knowledge of practice, as a source of scientific knowledge, and of the systematization itself, in relation to the praxis of liberation, that can be shared, reinterpreted and reconstructed with / by other experiences, spaces and subjects.
Repercussões cardiovasculares de um treinamento multicomponente em idosos pré-frágeis
(Universidade Federal de São Carlos, 2019-02-08)
Buto, Marcele Stephanie de Souza
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Takahashi, Anielle Cristhine de Medeiros
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https://lattes.cnpq.br/8336705133403404
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https://lattes.cnpq.br/7436622763487036
Frailty syndrome is described as a clinical state of vulnerability to stress resulting from the decline of resilience and physiological reserves related to aging. As Frailty progresses, homeostasis maintenance become affected, as well the interactions between the physiological systems and may impair the cardiovascular control by the autonomic nervous system (ANS). Considering the multidimensionality feature of Frailty, complexity measures such as Sample entropy (SampEn) and baroreflex sensitivity (BRS) may be more adequate tools to measure these interactions in cardiovascular dynamics. For Frailty management, multicomponent interventions have been shown to be effective in physical functions, functional capacity and frailty status, mainly in intermediate stages (pre-frailty). Nonetheless, it is unclear if it would also have beneficial repercussions in cardiovascular control as well as restoring the HR complexity and BRS. Thus, this thesis is divided into two studies. The study I "Multicomponent exercise training does not improve cardiovascular control in prefrail older adults: a blinded randomized clinical study" aimed to verify if a multi-component training of 16 weeks would have effect in the cardiovascular control of prefrail older adults. The results showed that multicomponent training was not effective in improving cardiovascular control as well as in the performance of the 6-minute walk test of prefrail older adults. The study II “Multicomponent exercise training in cardiovascular complexity in prefrail older adults: a blinded randomized clinical study” aimed to evaluate the efficacy of multicomponent training in the HR complexity and BRS in prefrail older adults. The results indicated there was no improvement in the HR dynamics as complexity and baroreflex. However, individuals who did not perform the training presented a worsening (reduction) of HR complexity over time. Thus, it is suggested the maintenance of HR complexity in prefrail older adults who participated in the intervention.
A legislação da educação a distância no Brasil: uma análise discursiva materialista dos conceitos de aluno e professor
(Universidade Federal de São Carlos, 2019-02-08)
Perez, Alessandra Fracaroli
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Brito, Luiz André Neves de
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https://lattes.cnpq.br/6863292359239733
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https://lattes.cnpq.br/2208750852826832
In this work, we aim to investigate the meanings movement of the words teacher and student in Distance Learning (hereinafter DL) through the statements contained in the discursive materiality of the legislations of this teaching modality. Our research is based on a contextualization of DL in Brazil, divided into three moments, describing the movements of this teaching modality focusing on the moment that interests this research. It is based on the theoretical-analytical field of Discourse Analysis (hereafter DA) of the French matrix starting from the theorizations of the philosopher Michel Pêcheux and other authors who contribute to DA theoretical field, besides the movements of the theoretical field that delineated the DA as it realizes today in Brazil. The corpus is composed of a legal file that includes the Law of Directives and Bases - LDB 9.394 of December 20, 1996 - art. 80 (BRAZIL, 1996), when distance learning begins at all levels of education and the decrees that regulate this law are: 2,494 February 1998 (BRAZIL, 1998a); 5,622 of December 19, 2005 (BRAZIL, 2005); 9,057 of May 25, 2017 (BRAZIL, 2017b). The methodology defined is the thematic path, proposed by Guilhaumou and Maldidier (1997), which allows us to go beyond writing, reconstructing the paths that build the event in history for the analysis of the discursive materiality present in this work. Our methodological course is as follows: from the selected files that compose the corpus of this research, we will start with the analysis of the moment that DL appears in all levels of education, based on LDB 9394/96. Subsequently we focus the analysis around the words teacher and student where we will analyze the direction of the same movements undertaken in the discursive materiality of the statements of decrees 2494/98; 5622/05; 9057/17. It seeks to understand the meanings movements of these words by analyzing how these notions are inserted, modified and moved in a certain historical moment, materialized in the decrees. Our analysis made it possible to understand that the beginning of DL brings a new subject-position for graduation. From that moment, we analyze that in a first moment the teacher is silenced, replaced by the technology. Now, the student, considered by the decree as self-taught, has a slip of sense as to its role in the teaching-learning process. In a second moment, we find that the teacher and the student retrieve their role in mediating the educational process. In a third moment, the role of the teacher gains a plurality of actions for their function and the student plays a central role in the teaching-learning process. It is noteworthy that there were movements of meaning regarding the role of the teacher and the student in this modality of teaching, however, today we can analyze that they return to their place of speech in this modality, thus safeguarding their actions in the teaching-learning process.
Isotopic analysis (δ13C, δ18O) of Pleistocene megafauna in Brazilian Intertropical Region: paleoecological and paleoenvironmental interpretations
(Universidade Federal de São Carlos, 2019-02-11)
Pansani, Thaís Rabito
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Dantas, Mário André Trindade
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https://lattes.cnpq.br/2337213908856661
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Pacheco, Mírian Liza Alves Forancelli
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https://lattes.cnpq.br/3481327026891705
By paleoecological reconstruction based on carbon isotopic analysis in Bahia State and Mato Grosso do Sul State, recently inserted in the Brazilian Intertropical Region (BIR), it was possible to infer ecological aspects of megamammals from these area, as well as the resources consumed (plants C3 and C4), niche width and niche overlaps between species. The organization of the ecological dynamics of the animals studied in Mato Grosso do Sul State is related of Holmesina paulacoutoi with the highest niche width, with a balanced diet, while Toxodon platensis is the one with the narrowest niche width, presenting high consumption of C4 grasses. Glyptotherium sp. and Eremotherium laurillardi showed balanced diet of C3 and C4 plants. In Bahia State, N. platensis presented the highest niche width, with mixed diet, and Equus neogeus the narrowest one, with an exclusive C4 diet. Consequently, the niche overlap for these both individuals was the lowest. E. laurillardi and T. platensis presented mixed-feeding diets, with predominance of C3 plants, while Palaeolama major predominance of C4 grasses. The oxygen values showed a relevant climatic difference in both areas, being able to infer that in Bahia State the environmental conditions were drier and hotter than in Mato Grosso do Sul State, during some age of the late Pleistocene. Within a notorious difference in the feeding behavior found in one of the common species of each localities (T. platensis), the great ecological plasticity of this species is recognized, as well as it is possible to explore possible ecological pressures and environmental dynamics that occurred in Brazil during specific paleoclimate moments in the late Pleistocene, characterizing behavioral changes and ecological strategies of its megamammals communities.
O caso da escola municipal Campos Salles (Heliópolis-SP) e a construção da autonomia
(Universidade Federal de São Carlos, 2019-02-11)
Hora, Carolina Laureto
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Gomes, Luiz Roberto
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https://lattes.cnpq.br/4768579559449929
;
https://lattes.cnpq.br/6324200834788665
The discussions in Dialetics of enligghtenmentby Adorno and Horkheimer and in the Theory of Semi-formation by Adorno, denounce that the cultural formation prevailing in capitalist society is based on technical rationality that leads men back to barbarism and defend an education that can emancipate the subjects instead of rendering their critical reflection unfeasible. Starting from the conception of emancipation developed by critical theorists as a theoretical strategy and based on a bibliographical survey about transformations proposed by new educational models, this research aims to identify, understand and analyze how the emancipatory ethos materializes in a school institution of the city of São Paulo, EMEF Presidente Campos Salles, which has a special pedagogical political project based on the model of a Portuguese democratic school, Escola da Ponte. Thus, an empirical study was developed in that institution that focused mainly on the established relationship between teachers and students, taken in the present work as a crucial element for the construction of the autonomy, in agreement with the studies of Paulo Freire. The methodology used for the data collection consisted of qualitative field research in which interviews were conducted with students and teachers, and the methodology of analysis used was the Objective Hermeneutics, through which the transcripts of the interviews were submitted to a collective analysis of members of the Critical Theory and Education Research Group, headquartered at the Department of Education of UFSCar - Ded / UFSCar. The conclusions of the present work, based on the case study of the school from São Paulo, point to a significant development of the autonomy of the interviewed subjects as a process, and not as something ready or determined by the institution itself. The present study seeks to contribute to studies in the area of Critical Theory in Brazil by promoting a critical analysis of innovative educational proposal in progress in the country.
Professor (a) youtuber?: as resenhas literárias audiovisuais e a revitalização do esquematismo da indústria cultural na cibercultura
(Universidade Federal de São Carlos, 2019-02-12)
Bet, David Silva
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Zuin, Antônio Álvaro Soares
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https://lattes.cnpq.br/5543562307373287
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https://lattes.cnpq.br/2205364981301004
In times of the Internet, social media has opened up space for new forms of production and access to knowledge, to the point where the search for audiovisual literary reviews has become a shortcut to formation through synthesis, summaries and short introductions. From the update of some critical categories of Max Horkheimer and Theodor W. Adorno, the present study aims to investigate aspects of the content and form of an audiovisual literary review in the context of the Cultural Industry of Cyberculture, available on YouTube about the book “Animal Farm” written by George Orwell. The objective was derived the following guiding question for empirical social research: in what sense is it possible to affirm that the audiovisual review of an intellectual content is committed to the process of cultural industry schematism? Through Adorno’s content analysis methodology, the examination focused on the presence of manifest and implied clichés in the reviews and in the comments of users that tend to hypostasize a certain way of conceiving the world – divided between “us” and “them”, the sentences harbor the authoritarian “it’s like this” and “the other” (outsider), respectively under the expressions “easy reading text” and “socialist of rare lucidity”. As paralyzers of any discussion, stereotyped words pasteurize the critical content immanent to intellectual production. Consumed as a kind of didactic material, the audiovisual literary review produced by the youtuber does not seem to have presented a strict commitment to the theme, since there was no clarification and no confrontation to mistaken comments from users and to conceptual misunderstandings about the work and life of Orwell.
Caracterização funcional parcial de dois genes de Xanthomonas citri potencialmente relacionados com a patogenicidade: XAC1006 (malato desidrogenase) e XAC0223 (proteína hipotética conservada)
(Universidade Federal de São Carlos, 2019-02-12)
Martelli, Ana Carolina Franco Severo
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Novo-Mansur, Maria Teresa Marques
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https://lattes.cnpq.br/1198926223396748
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https://lattes.cnpq.br/0215905712415350
The bacterium Xanthomonas citri subsp. citri (XAC) is the cause of citrus canker, a disease that affects many species of citric plants, causing drop in productivity and losses to producers. Many proteins have been detected by proteomic analysis and related to the invasion and dissemination of the bacterium in the citrus host. In the present work, biochemical techniques were applied for the obtaining and partial functional characterization of two XAC genes: XAC1006 (malate dehydrogenase - MDH) and XAC0223 (conserved hypothetical protein), both detected in previous proteomics studies performed at the Laboratory of Biochemistry and Applied Molecular Biology (LBBMA)/UFSCar as potentially involved in XAC´s pathogenicity. The conserved hypothetical protein (XAC0223) does not have a described function in literature for XAC, but its gene sequence analysis by bioinformatics tools shows similarities with membrane proteins and outer membrane vesicles (OMVs) of known function in other species. It was possible to characterize it partially by pathogenicity test with a deletion mutant of this ORF, previously obtained, which apparently presented greater virulence than the wild XAC, which may corroborate the hypothesis that it may be a protein detected by the host plant which can trigger their defense responses. MDH was described as a signature protein in XAC cells surface under in vivo infectious conditions, which has also been described for other pathogenic organisms, as a determinant protein in their infectious processes. In this work, a recombinant MDH was obtained in the native form with confirmed enzymatic activity, and anti-MDH antibodies were also produced and used in Western blot, providing more evidence of its possible presence on XAC´s surface under infectious conditions. It is hoped, through the obtained results, to contribute to the knowledge of the pathogenicity mechanisms of Xanthomonas sp., confirming potential targets of biotechnological interest against the disease and helping in its future combat.
Controle postural e fragilidade: efeitos de diferentes tarefas e de um treinamento multicomponente
(Universidade Federal de São Carlos, 2019-02-12)
Carmelo, Verena de Vassimon Barroso
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Takahashi, Anielle Cristhine de Medeiros
;
https://lattes.cnpq.br/8336705133403404
;
https://lattes.cnpq.br/7496298739077529
The frailty syndrome is highlighted both the aging process, since it has adverse outcomes such as death, hospitalization, institutionalization, falls and functional dependence. In this syndrome there would be a greater reduction of the physiological reserves and difficulty in maintaining the homeostasis due to a reduction of the physiological complexity. Since fall is an important outcome in this syndrome, it would be interesting to evaluate the postural control through measures of complexity and in challenging conditions, not only at rest. Thus, the Study I, titled "Impact of different demands on the postural control of prefrail older adults", aimed to compare the complexity of center of pressure (CoP) displacements of prefrail older adults in response to different stimuli: visual deprivation, cognitive demand and postural change. The results showed that the complexity of CoP displacement remained the same after the postural transition in the anteroposterior (AP) direction, as well as in tasks with closed eyes and with cognitive demand in the mediolateral (ML) direction. It is suggested that these activities could be added into rehabilitation programs for this population. As transitions between frailty stages are spontaneous, measures that may reduce the progression of frailty, such as exercise, should be taken into account. Thus, the Study II entitled "Effect of multicomponent training in postural oscillation complexity in prefrail older adults" aimed to investigate the effect of a multicomponent intervention (aerobic, balance, resistance and flexibility exercises) on the complexity and traditional measures of CoP displacements in the AP and ML directions with the eyes open and closed. The data showed that multicomponent training improved the integration of systems that control the prefrail balance, especially in challenging conditions, such as with closed eyes.
Indicadores de qualidade do solo em diferentes sistemas de manejo
(Universidade Federal de São Carlos, 2019-02-12)
Fernandes, Flavia Santos
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Tonello, Kelly Cristina
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https://lattes.cnpq.br/6466418270059965
The use and management of the soils have caused physical-water changes of them. The evaluation of these modifications is necessary for the dimensioning of the physical quality of the soils, in order to characterize and understand the dynamics of the changes in the environment. In this sense, this study has the goal of characterize and evaluate the influence of different systems of use and management of the soil. The study was conducted at the São João site, located in the city of Salto de Pirapora, SP, Brazil, where the mechanical resistance to penetration, hydraulic conductivity and soil infiltration were evaluated over a year in three management systems: (1) Agroforestry System (SAF); (2) lytic planting (LIC) and (3) area in transition for banana plantation (PAS). In each treatment, the soil cover was also measured using a 0.24m² quadrant, as well as undisturbed soil samples in the 0-10 cm layers to determine their density and humidity. Rainfall data were recorded monthly to correlate with the physical-water attributes of each treatment. The systems with the highest and most frequent management (SAF and PAS) presented better results in relation to soil quality than the system with lower management (LIC), except for the parameters humidity and soil cover where the LIC presented better conditions. The physical characteristics of SAF and PAS were similar to each other and different from the LIC area. The physical characteristics of SAF and PAS were similar to each other and different from the LIC area. Thus, it can be concluded that DS, K, VI, RMSP in SAF and PAS soils showed a better quality in relation to LIC.
Myrtaceae do legado das águas – Reserva Votorantim, Tapiraí, São Paulo, Brasil
(Universidade Federal de São Carlos, 2019-02-12)
Sant'Ana, Gabriela Zominhani
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Capelo, Fiorella Fernanda Mazine
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https://lattes.cnpq.br/0400014722017129
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https://lattes.cnpq.br/3264706434837645
Myrtaceae in Brazil includes approximately 1030 species, circumscribed in 23 genera, which characterizes it as the 8th family in number of species in the Brazilian flora. It has great ecological importance and is present in several phytogeographical domains, especially in the Atlantic Forest. The Legado das Águas - Reserva Votorantim is located in the municipalities of Tapiraí, Miracatu and Juquiá, next to large areas of environmental conservation, such as the Carlos Botelho State Park, forming a valuable ecological corridor in the Serra de Paranapiacaba. They are regions where the predominant vegetation is Ombrophylous Dense Forest, regions with high biodiversity in the state. The aim of this work is the taxonomic survey of Myrtaceae species occuring in the Legado das Águas - Reserva Votorantim. For that purpose, we carried out collection expeditions in the area as well as visits to the herbaria with expressive collections of plants collected in the area. The 39 species sampled in the area are presented through photographic records, descriptions and identification key, with Myrcia and Eugenia being the most expressive genera, with the highest number of species (17 and 14, respectively). The other genera sampled in the area were: Campomanesia (three species), Myrceugenia (two species) and Plinia (three species). The Myrtaceae species occurring in the Legado das Águas - Reserva Votorantim correspond to about 14% of the species of this family in the Atlantic Forest for the state of São Paulo.
Condições sensíveis à atenção primária como dispositivo de gestão do cuidado em saúde: a apropriação pelos usuários do SUS
(Universidade Federal de São Carlos, 2019-02-13)
Malvezzi, Edson
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Ogata, Márcia Niituma
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https://lattes.cnpq.br/3274294833403570
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https://lattes.cnpq.br/8828325395421877
Despite advances in the last thirty years, the Brazilian public health system still faces impasses for its consolidation as a social policy to foster citizenship and the challenge of breaking with the traditional care model in the daily services. With the perspective of structuring new forms of care management, organization of supply and guarantee of continuity, the "ICSAP Project - hospitalizations for conditions sensitive to primary care" in the city of Campinas-SP was designed and implemented in 2012, which seeks to articulate and negotiate actions between the services of a specific territory, especially the basic health units and the hospital, in order to qualify and guarantee the access and continuity of the care of its users. Taking this initiative as an object, this research aims to analyze the perceptions of these users regarding their appropriation of public health policy, in particular the understanding, repercussions and participation in the processes of organization, operationalization and evaluation of the health system and services in which they are inserted. This is a qualitative study with a documentary survey and data collection through interviews with users, the results being systematized according to content analysis and discussed in the light of critical hermeneutics and the "Paidéia" reference. The findings demonstrate that users recognize the Unified Health System as a public policy, aiming to know their logic of operation and the benefits offered by their services when they need health care; in an analogous way, recognize and perceive the effects of the "ICSAP Project", especially for the institution of new practices in the care after hospital hospitalization episode in the basic units; however, it is evidenced that these users were not included in the institutional spaces of social participation for discussion, organization and evaluation of this initiative, as well as the health system in general, demonstrating that there are still challenges to their effective appropriations by society. From this scenario, it is hoped to contribute to the reflection in the different instances of this system, especially in Campinas, and in society in general, about the necessary expansion of the inclusion of users in the deliberative processes of both the "ICSAP Project" and in the organization of the health system.
A bibliometria e a pesquisa interdisciplinar nas ciências ambientais
(Universidade Federal de São Carlos, 2019-02-13)
Romanelli, João Paulo
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Boschi, Raquel Stucchi
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https://lattes.cnpq.br/5774095142035730
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Tanaka, Marcel Okamoto
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https://lattes.cnpq.br/2768658925977757
In recent years, research results on Environmental Sciences have grown in complexity and proportion, and this has required from the scientists the capacity to synthesize information from different sources to support holistic analyzes and generate new knowledge. Bibliometric analysis appears in this context as an analytical tool with high potential to support the systematic synthesis of information and the analysis of the outptus of science. In this thesis, we seek to evaluate how bibliometric tools and methods can contribute to the generation of new knowledge and analysis of science, presenting five articles developed from topics of Environmental Sciences and its subfields. Specifically, in Chapter 1 we explored different forms of network analysis and introduced an unprecedented methodology of keyword analysis to detect research gaps in the area of Restoration Ecology. This same methodology was used in Chapter 2, where we investigated the research on the enzymes immobilization. We introduced spatial analysis resources to complement the discussion of network analysis and analyzed the dynamics of bibliometric indicators in different periods (27, 10 and 5 years). In Chapter 3, we emphasized country-stratified research, and through the co-occurrence criterion of keywords we present the main research topics on electronic waste management. In Chapter 4, two distinct focuses of study were presented: an applied research related to the restoration of ecosystems; and a practical and theoretical approach related to qualitative chemistry, intermediated by the Laser-Induced Breakdown Spectroscopy (LIBS) technique and by bibliometrics, respectively. In this chapter, we present a new perspective on the use of bibliometric indicators to support research. Finally, in chapter 5 we had the opportunity to work with the smallest database among the studies of this thesis, which generated several insights on the performance of the bibliometric indicators in "narrow" bases; which was analyzed under Ostrom's precepts on common forest management. From the perspective of bibliometrics scholars related to the non-LIS community (Library and Informations Science), we had as general objective: to discuss and synthesize information on the use of bibliometric indicators in the research of Environmental Science topics. The results indicate, for a great diversity of subjects, that the application of bibliometric tools is an effective way of revealing the current state of the research and its directions, which can favor the development of new studies and scientific production in Environmental Sciences.
Corpo, câmera e ação: oficinas de experimentação audiovisual com estudantes de ensino médio
(Universidade Federal de São Carlos, 2019-02-13)
Silva, Eduardo Luiz Corrêa da
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Costa, Alan Victor Pimenta de Almeida Pales
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https://lattes.cnpq.br/5414466437997230
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https://lattes.cnpq.br/6871345288328401
This work is a reflection on the corporate and sonorous productions of students that appear in audiovisual devices during a semester in a discipline called Audiovisual Food Workshops. Reports on the formation of the body as practical, historical, cultural and social in distinct contexts are developed by space and time. We adopted the bibliographic research The chance to perceive different forms of production of the body. Historiographical research grounded the production of audiovisual images, conducting student workshops, allowing them to produce points of view and approaches, so that they could construct a creative and fabulous relationship with their daily lives. And from this perspective, audiovisual devices can respond to sensitive experience and act in a way that liberates discourses, understandings and possibilities of the world. After the realization and interpretation of the material produced in the Workshops, we were able to observe the use of audiovisual materials in school to help transform the processes in their teaching and development contexts about their forms of expression and feel the world.
Paralelização de algoritmos de busca de documentos mais relevantes na web utilizando GPUs
(Universidade Federal de São Carlos, 2019-02-13)
Gaioso, Roussian Di Ramos Alves
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Senger, Hermes
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https://lattes.cnpq.br/3691742159298316
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https://lattes.cnpq.br/3536210071193629
Search engines are facing performance challenges because of the large number of documents and the increase of query loads in the Web environment. The success of a search engine is related to the ability of the query processing system to find documents that match the needs of information expressed in user queries in a short time interval. Despite the large amount of documents, users are more interested in fewer results in a query. This causes few documents to be highly relevant in most queries. DAAT dynamic pruning algorithms have been exploring the efficiency of query processing systems, avoiding wasting time sorting documents that are not likely to be relevant. To handle the scale and dynamics of user query traffic, query processing needs to make efficient use of hardware resources. The main objective of this doctoral thesis is to investigate the use of parallel computing in the process of identifying the most relevant documents to a given query in the GPU architecture. For this, strategies of parallelization of algorithms that aim to reduce the latency of response of a given query and to increase the flow of queries are proposed and evaluated in the GPU. The parallelization proposals are well suited to the category of DAAT algorithms and dynamic pruning algorithms. In the DAAT category, partitioning strategies are offered in a way that performs an investigation into the location of occurrences of the same document in the memory hierarchy of the GPU. At the level of dynamic pruning algorithms, threshold propagation policies among processors are proposed and the impacts generated on the efficiency of the parallel algorithms are analyzed. To verify efficiency in practice, the parallel proposals were implemented and tested in the Pascal GPU architecture and obtained a performance of 4x to 40x relative to the fundamental algorithms.