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Browsing by Issue Date, starting with "2024-11-05"

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    Visão de um estudante sobre a formação médica na UFCar: uma narrativa crítica-reflexiva
    (Universidade Federal de São Carlos, 2024-11-05)
    Machado, Gabriele Vitoria Gerciano
    ;
    Stefane, Claudia Aparecida
    ;
    https://lattes.cnpq.br/7808406751232968
    ;
    https://orcid.org/0000-0003-2090-4878
    ;
    https://lattes.cnpq.br/3440322485330270
    This Course Completion Work (TCC) presents a reflection on the academic trajectory from a student's personal point of view. To this end, the university admission process is presented chronologically, such as the Political Pedagogical Project of the course is structured and an overview of the experiences experienced in the three educational cycles. The constructivist approach of the course helped to improve learning and guided the student to a practical patient-centered clinic, promoting empathy, responsibility and respect in the doctor-patient relationship. The COVID-19 pandemic had a significant impact on training, bringing academic and personal losses that required a lot of effort and work to alleviate them. It is concluded, therefore, that the constructivist methodology, even though far from perfect, provides valuable tools to students to deal with adversity and promotes longitudinal knowledge practical, theoretical and attitudinal.
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    Percepção de estudantes da saúde acerca do papel da espiritualidade na processo de saúde-doença
    (Universidade Federal de São Carlos, 2024-11-05)
    Lopes, Agatha Moura
    ;
    Valete, Cristina Ortiz Sobrinho
    ;
    https://lattes.cnpq.br/3246791895201559
    ;
    https://orcid.org/0000-0002-6925-4346
    ;
    https://lattes.cnpq.br/1715142284598797
    This article discusses the importance of spirituality in health and the perception of health students about their preparation to address the topic. Spirituality has had a role recognized by the World Health Organization (WHO) since 1978, when it was included in the definition of health as a dimension that affects well-being. Studies show that spirituality can positively influence patient recovery, reducing anxiety and improving coping with illness. However, spirituality is often confused with religion, and it is necessary to differentiate between them: spirituality involves the search for meaning in life, while religion is linked to specific beliefs and practices. Despite the importance of spirituality in the healthcare context, many professionals encounter barriers, such as lack of training and discomfort with the topic. The reported study was carried out at the Federal University of São Carlos, with 71 Medicine, Physiotherapy, Nursing and Occupational Therapy students. Most students recognize the influence of spirituality on health, but almost half feel unprepared to address the topic with patients, which points to a deficiency in the academic curriculum. Although 85.9% of those interviewed consider it important to include spirituality in their training, only 29.6% had contact with the topic during their undergraduate studies. It is concluded that, despite the recognition of the importance of spirituality, there are gaps in the training of students, which can affect clinical practice and comprehensive patient care.
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    Para além da medicina: uma imersão reflexiva
    (Universidade Federal de São Carlos, 2024-11-05)
    Koyama, Camila Takae
    ;
    Martins, Joyce do Rosario
    ;
    https://lattes.cnpq.br/3476750240513111
    ;
    https://lattes.cnpq.br/2706673821203380
    A text that invites you to reflect on the academic journey throughout a medical degree, contemplating literature, ancestry, love, and academic achievements. The reflections permeate the temporality that passes through me, so that I discuss the reasons that led me to medicine and the perspectives that surround me at the end of the course. I am a story and here I present a part of myself.
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    Relato de experiência na graduação em Medicina na UFSCar
    (Universidade Federal de São Carlos, 2024-11-05)
    Espósito, Maria Clara Cavalcante
    ;
    Stefane, Claudia Aparecida
    ;
    https://lattes.cnpq.br/7808406751232968
    ;
    https://orcid.org/0000-0003-2090-4878
    ;
    https://lattes.cnpq.br/0372059479555515
    This work consists of a report on the experience of a medical student throughout his graduation at the Federal University of São Carlos (UFSCar), covering both the personal and academic trajectory regarding the development of an initiation project scientific research focused on Chronic Obstructive Pulmonary Disease (COPD). Using a qualitative and reflective approach, the study aims to document the perceptions, challenges and learning acquired during six years of medical training, in addition to discussing the impact of the Covid-19 pandemic in medical teaching and practice, especially with regard to emergency remote teaching and internship activities. Organized in text format theatrical, it is divided into six acts, representing in a subjective - and almost dreamlike - way the the author's deepest emotions and anxieties, which even with the fog of partiality permeating the writings, it seeks to relive the most striking facts of these last six years.
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    Reflexões acerca do curso de medicina por um estudante do 6º Ano
    (Universidade Federal de São Carlos, 2024-11-05)
    Gaion, João Pedro De Barros Fernandes
    ;
    Martins, Joyce do Rosario
    ;
    https://lattes.cnpq.br/3476750240513111
    ;
    https://lattes.cnpq.br/4133264417551561
    This work, structured as a critical-reflective narrative, as outlined in the Political Pedagogical Project (PPP) of the Medicine course at the Federal University of São Carlos (UFSCar) as a format for the Final Paper, aims to narrate the author’s experiences and reflections over the six years of medical education, within the context of a course based on active learning methodologies, which were shaped by the SARS-CoV-2 pandemic. Based on these experiences, and through a critical analysis of the PPP of the course, the Constructivist Spiral as a teaching-learning method, and the provisions of the National Curriculum Guidelines for undergraduate medical courses, this work seeks to provide a critical analysis of the reality of the Medicine program at UFSCar.
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    Óleos essenciais de tangerinas para manejo de podridão floral dos citros (Colletotrichum abscissum)
    (Universidade Federal de São Carlos, 2024-11-06)
    Zunkeller, Andreza Bonetto
    ;
    Bastianel, Marinês
    ;
    https://lattes.cnpq.br/2523177587459092
    ;
    Schinor, Evandro Henrique
    ;
    https://lattes.cnpq.br/2162760988837984
    Citrus farming in Brazil has been facing phytosanitary problems that lead to significant production losses, among which postbloom fruit drop (PFD) caused by the fungus Colletotrichum abscissum stands out. This study aimed to investigate the action of tangerine essential oils (EOs) on the fungus C. abscissum for the management of CBF. EOs of three tangerine varieties: IAC 2019Maria mandarin, Murcott IAC 221 tangor and Late IAC 585 willowleaf, extracted from unripe and ripe fruits at different dosages (0; 2; 4; 8; 16 and 32 (µL mL-1) were evaluated for the percentage of inhibition of mycelial growth, speed index and area under the mycelial growth curve, sporulation and germination of in vitro spores of the fungus C. abscissum. In addition, the chemical components present in the EOs and the yield and their relationship to the diameter of the fruits and peel thickness were verified. Given the results found in vitro, the disease control capacity in detached flowers of Tahiti acid lime was analyzed, in addition to the potential of the EOs to activate defense mechanisms in plants, by the action of peroxidase, polyphenol oxidase and phenylalanine ammonia-lyase. Limonene was the main compound found in the EOs of tangerines extracted from unripe and ripe fruits. It was observed that the Late IAC 585 willowleaf presented a higher EO yield when extracted from unripe fruits. There was a positive correlation between yield and epicarp thickness of the peel for both EOs from unripe and ripe fruits. In the in vitro test with EOs extracted from unripe fruits, the Late IAC 585 willowleaf demonstrated a greater capacity to inhibit mycelial growth and when using the EO extracted from ripe fruits, the IAC 2019Maria mandarin was more efficient in controlling the pathogen. The EOs of both varieties were effective in controlling sporulation when extracted from unripe fruits. For ripe fruits, there was a difference only between dosages, with a sharp decrease in the number of conidia with increasing dosage. The EO of the IAC 2019Maria mandarin stood out for presenting control of spore germination at lower doses, when compared to the other varieties, for both unripe and ripe fruits. When applied to detached flowers, the EO had no systemic action on the flowers to prevent C. abscissum infection, in addition to not having the ability to activate the plant's defense mechanisms.
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    As diferentes perspectivas da pediatria a partir das vivências de uma acadêmica de medicina: uma narrativa reflexiva
    (Universidade Federal de São Carlos, 2024-11-06)
    Nogueira, Marina Mourad
    ;
    Germano, Carla Maria Ramos
    ;
    https://lattes.cnpq.br/1685750854841732
    ;
    https://orcid.org/0000-0001-5030-7164
    ;
    Stefane, Claudia Aparecida
    The word “pediatrics” is of Greek origin, formed by the combination of the terms paidos, which means “child” and iatreia, which means “healing process”, and is used to name the medical specialty dedicated to child care, from birth to adolescence. Since the end of the 19th century, teaching Pediatrics gained prominence in Brazilian medical training, remaining until today as one of the great areas of learning. The medical course at UFSCar includes in its pedagogical project the broad area of ​​child health and of the adolescent, to be studied during the 6 years of graduation. Therefore, The objective of this work is to demonstrate the impact of different experiences on pediatrics throughout a degree in medicine and demonstrate the importance of this specialty in medical and humanitarian training.
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    Estudos in silico dos modos de ligação dos hormônios tireoidianos T3 e T4 com a Proteína Transportadora Albumina Sérica Humana HSA
    (Universidade Federal de São Carlos, 2024-11-06)
    Barbosa, Elisa Guimarães
    ;
    Freire, Thales Souza
    ;
    https://lattes.cnpq.br/0320608221793070
    ;
    Caracelli, Ignez
    ;
    https://lattes.cnpq.br/8956527354576143
    In the present work, the binding mode and molecular interactions between thyroid hormones (T4, T3 and the positional isomers of T3 – T3IP) and the transporter protein (HSA) were investigated. T4 has 4 iodine atoms and T3 has 3. Analysis of the crystallographic structures of the T4-HSA complexes (1HK1,1HK2-R218H, 1HK3-R218P - with fatty acids and 1HK4, 1HK5-R218H- without fatty acids) was carried out. The knowledge acquired was used in the study of molecular docking to understand T3 since there is no crystallographic structure of HSA with T3, with T3 being the active form of thyroid hormone in target cells. It was observed that HSA is capable of differentiating T4 from T3. Another important point was to study 3 cases of HSA-T4 and HSA-T3 complexes, R128, R218H, R218P and explain the difference in HSA-hormonal ligand affinity. In the case of the T3 ligand, which has 3 iodine atoms, with a specific position, 4 positional isomers, T3IP, were evaluated. Docking studies showed that these compounds are different compared to HSA. The presence of fatty acids in the crystallographic complexes of the native protein and R218H mutant protein affected the availability of binding sites, limiting the interaction with T4 to a single site (Cleft). The analysis of T3 positional isomers (T3IP) showed that the structural flexibility of the ligands is an important factor in determining interactions with HSA. The findings of this study can be applied in the development of therapeutic strategies aimed at transporting thyroid hormones in conditions of genetic mutations or metabolic disorders. Detailed understanding of the differences in affinity between T3 and T4 and the influence of mutations in HSA provides a solid basis for future research focused on modulating the bioavailability of these hormones. The results presented here serve as a starting point for experimental investigations that can validate the trends observed in silico studies and explore new applications in the field of endocrinology and biotechnology.
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    Influência do intemperismo da Região Amazônica nas propriedades físicas e mecânicas da madeira Angelim- Vermelho na cidade de Porto Velho
    (Universidade Federal de São Carlos, 2024-11-06)
    Pessôa, Poliana de Melo
    ;
    Almeida, Diego Henrique de
    ;
    https://lattes.cnpq.br/7043956540589502
    ;
    https://orcid.org/0000-0002-6220-4004
    ;
    https://lattes.cnpq.br/8927885751118440
    Despite the advantages of wood, it is common to use it in environments subject to exposure to biotic and weathering factors, causing its natural manipulation, damaging physical and especially mechanical properties of interest, which can affect the useful life of buildings. In this context, the largest reserve of biological diversity in the world is found in the Amazon. However, although this region has great potential to produce native woods, the sector is still predominantly dominated by the Eucalyptus and Pine species. In addition, weathering varies according to the season and location, which implies that the climatic conditions of the Amazon region can be even more aggravating to the handling of wood compared to other regions, due to its climatic characteristics, as it has a hot and humid climate, with two well-defined seasons, one dry and one rainy, since in the latter, precipitation occurs in intense forms. Therefore, it is necessary to conduct studies on the action of weathering in the Amazon region on native woods, to evaluate and determine the importance of decreases in mechanical properties, since these can even reduce the resistance class imposed in the project. Thus, the present research project aims to evaluate the influence of the action of weathering in the Amazon region in Porto Velho, Rondônia, on the physical and mechanical properties of Angelim-Vermelho wood (Dinizia excelsa Ducke), by exposing specimens of the wood in question to natural weathering, and subsequently evaluating, through laboratory tests, its physical properties of colorimetry and density, and mechanical properties of hardness, modulus of elasticity parallel to the fibers and resistance to joint parallel to the fibers. In addition, a systematic literature review was carried out to verify the effects of weathering on wood found in the literature. From statistical analyses it was possible to verify that despite causing damage to the physical and mechanical properties of the wood, weathering does not significantly manipulate the wood under study in the time delimited for this research, with the exception of the colorimetry and hardness properties parallel to the fibers, making it necessary to extend the exposure time in order to correctly verify its behavior in the face of the climatic factors of the Amazon region.
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    O uso de simulação realística com atores no desenvolvimento de habilidades de comunicação
    (Universidade Federal de São Carlos, 2024-11-07)
    Yamashita, Kaori Maria Carolina
    ;
    Neves, Fábio Fernandes
    ;
    https://lattes.cnpq.br/2652568399519714
    ;
    https://lattes.cnpq.br/3651649007146855
    Being a good communicator is essential for effective medical practice. Realistic simulation is a valuable learning tool that does not expose patients to unnecessary risks, and its use has become widespread in medical education. Therefore, this final paper investigates the association between realistic simulations with actors and the development of communication skills. The summary of the relevant literature was prepared using the PubMed platform, the ABEM database, and articles recommended by the project advisor. In addition, the author's notes taken throughout the undergraduate course were also consulted. It was observed that simulation had a beneficial impact in the first year. The feedback process is an essential phase that has significantly impacted performance improvement. Standardized patients increase the realism of the scenario and can also participate in reflection, providing alternative perspectives. However, favorable results depend on meticulous preparation, and there is insufficient empirical data regarding the cost-benefit ratio and the ability to transfer the acquired skills to the management of actual patients. The author's experience recognizes these simulations' immediate and long-term positive impact. It reflects on interactions with actual patients who have benefited from the skills learned through the simulations. However, there is recognition of the need to specify the competencies to be addressed each year, as well as to implement more systematized feedback processes that allow for more uniform learning and facilitate the identification of areas for improvement.
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    Efeitos do clima e da paisagem nos padrões de distribuição e de riqueza de felinos da Mata Atlântica
    (Universidade Federal de São Carlos, 2024-11-08)
    Ribeiro-Souza, Paula Danyelle
    ;
    Graipel, Maurício Eduardo
    ;
    https://lattes.cnpq.br/3039321868126712
    ;
    Pires, José Salatiel Rodrigues
    ;
    https://lattes.cnpq.br/3412204514901170
    Two of the most significant forces affecting biodiversity worldwide are Global Climate Change (GCC) and Land Use and Land Cover Change (LULC). To better understand the impacts of GCC and LULC on biodiversity, it is crucial to analyze how these factors interact with terrestrial ecosystems, including the Atlantic Forest biome. In this context, the main objectives of this thesis were: (1) to evaluate how climate and landscape currently influence the distribution and richness patterns of the species Leopardus emiliae, L. guttulus, L. wiedii, Herpailurus yagouaroundi, L. pardalis, Puma concolor, and Panthera onca in the Atlantic Forest; (2) to investigate the extent to which this distribution is protected by Strict Protection Conservation Units (SPCUs); and (3) to understand how the taxonomic richness patterns of wild felines will respond to GCC and LULC in the Atlantic Forest by 2050. To achieve the first and second objectives, species distribution modeling were used to estimate suitable areas for both the current scenario and the year 2050, for the distribution of each species and for the taxonomic richness of felines. The models were created using climatic and landscape variables, employing different algorithms. All species occurrence data were obtained from data papers, other scientific articles, scientific collections, and databases. The results indicated that only 30% of the Atlantic Forest is currently suitable for feline richness, with areas of low species richness located in northeastern Brazil and Argentina. Only 9% of these suitable areas are covered by FPAs, highlighting a significant gap in feline conservation. Species such as L. emiliae (1.37%) and P. onca (1.97%) are the least protected. Projections for 2050 indicated that the loss of suitable habitat will be more pronounced under the pessimistic scenario (~87%) due to the combination of GCC and LULC. Additionally, about 61% of the analyzed areas in the Atlantic Forest have low permeability for feline richness. The results of this thesis underscore the urgent need for conservation actions in the Atlantic Forest, including the implementation, maintenance, and expansion of FPAs, landscape restoration, and increased connectivity between suitable areas. These measures could mitigate the negative impacts of GCC and LULC on feline richness in the Atlantic Forest.
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    Avaliação em língua inglesa com crianças na Educação Infantil: a participação no processo avaliativo
    (Universidade Federal de São Carlos, 2024-11-08)
    Lucena, Priscilla Pina de
    ;
    Barbirato, Rita de Cassia
    ;
    https://lattes.cnpq.br/6962819573963727
    ;
    https://orcid.org/0000-0001-5896-9787
    ;
    https://lattes.cnpq.br/1360118078214772
    This qualitative interpretive collaborative ethnographic-based research investigated the participation of 5-year-old children during the writing of the English language assessment report in a private school in the city of São Paulo. We investigated 1) how children can participate in their English learning assessment process when the instrument is the class assessment report; 2) what challenges arise for the educator and for the children regarding this participation. Firstly, we analyzed official Brazilian educational documents to understand what is expected at this school stage. Next, we researched the conception of childhood and children to understand how their participation and rights were achieved. It was also important to conceptualize our understanding of participation. After this initial analysis of issues related to childhood, we researched theories about assessment in Early Childhood Education to understand the assessment scenario in Brazilian schools. Furthermore, we presented questions related to language teaching for children and English language assessment with children. The method used to study these issues with children was participant observation, and the data collection instruments included class observation, audio recording, field diary, interview, questionnaire, teacher planning, and school pedagogical project. Data triangulation led to results that showed us that children can participate in the assessment process by singing, gesturing, remembering situations, and adding information.
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    O ensino de ortopedia e traumatologia na graduação em medicina: como a faculdade nos prepara para a vida profissional?
    (Universidade Federal de São Carlos, 2024-11-08)
    Penido, Vitor Brasil Pereira
    ;
    Neves, Fábio Fernandes
    ;
    https://lattes.cnpq.br/2652568399519714
    ;
    https://lattes.cnpq.br/7470108285867678
    This Course Conclusion Work evaluates the teaching of Orthopedics and Traumatology during the undergraduate course in Medicine at UFSCar, based on the author's educational background, and proposes a critical-reflective analysis of the gaps in the average training of general medical in comparison with best practices recommended for the development of theoretical-practical skills and application in real scenarios, occupied by newly graduated doctors. In this way, the text reflects on orthopedic education and the enhancement of newly trained doctors' ability to manage the most prevalent orthopedic complaints, especially within primary care and emergency care settings. The methodology includes research in databases such as SciELO and PubMed and explores theoretical teaching and practical experiences throughout the course.
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    Aplicação do aprendizado de máquinas para classificação de cooperativas de crédito em risco de encerramento
    (Universidade Federal de São Carlos, 2024-11-08)
    Oliveira, Ana Carolina Alcantara de
    ;
    Carvalho, Flávio Leonel de
    ;
    https://lattes.cnpq.br/9615144436796386
    ;
    https://orcid.org/0000-0002-8488-9382
    ;
    https://lattes.cnpq.br/9763606671341913
    Introduction Credit cooperatives, entities formed by individuals with common economic interests, aim to achieve both the economic and social goals of their members (McKillop & Wilson, 2011). Given this, it is essential to monitor the risks associated with these entities, especially those related to credit granting, due to potential conflicts of interest. Determining the most relevant indicators for categorizing cooperatives with a potential for discontinuity can lead to more effective monitoring and support decision-making in the management process. Research Problem and Objective Due to the high risks involved in potential conflicts of interest, it is essential to monitor and assess capital adequacy, asset quality, management quality, profitability, and liquidity, which can be carried out using the CAMEL methodology. However, the large number of indicators can make it difficult to analyze the actual financial situation of these organizations. Thus, this study aimed to identify the most relevant accounting indicators for classifying Brazilian credit cooperatives at risk of future closure. Theoretical Framework Several studies (Silva, Santos, Ranciaro, 2023; Vieira, Bressan V., Bressan A., 2018) highlight the importance of performance analysis in credit cooperatives. Although their objective is not profit generation, cooperatives need to manage their resources efficiently to provide members with higher returns on their investments and better rates for financial operations. Understanding these results is essential to support their social and economic functions and ensure their survival in the financial system. Methodology To achieve this, the study employed the machine learning methodologies Random Forest and K-Nearest Neighbors (KNN). The Random Forest model enabled the identification of the most relevant indicators, while the KNN model was used to classify cooperatives based on their potential risk of closure. Using a sample of 8,552 observations from single credit cooperatives between 2018 and 2022, the dataset was divided into a training set (80% of the sample) and a test set (remaining 20%). Results Analysis The results from non-parametric mean difference tests showed that the analyzed CAMEL indicators exhibited statistically significant differences in the years preceding closure. However, the model achieved 92.9% accuracy in predicting the future operational status of the cooperatives, with a 93% success rate for active cooperatives but only 46% for those classified as closed. Thus, while the model was ineffective in identifying closed cooperatives, it was efficient in classifying the most impactful indicators. Conclusion Due to the low accuracy in identifying closed cooperatives, the study concludes that using the six most impactful indicators provides a similar level of information to that obtained with the full set of CAMEL indicators. Additionally, given the high error rate in classifying credit cooperatives at risk of closure, the findings suggest the need to explore alternative models or techniques for predicting credit cooperative closures. Contribution / Impact This study aimed to identify the most relevant CAMEL indicators for classifying cooperatives at higher risk of closure and to predict closure probabilities using machine learning. The main contribution lies in identifying key financial indicators for monitoring the performance of credit cooperatives. It is expected that this study will contribute to improving the oversight of these institutions and strengthening the cooperative system, enabling proactive interventions to reduce their vulnerabilities.
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    Narrativa reflexiva: A jornada percorrida para honrar uma promessa
    (Universidade Federal de São Carlos, 2024-11-09)
    Luz, Leonardo Lopes Braga
    ;
    Hirakawa, Humberto Sadanobu
    ;
    https://lattes.cnpq.br/5250668837433200
    ;
    https://orcid.org/0000-0002-7845-3320
    ;
    https://lattes.cnpq.br/0110188052557836
    This Undergraduate Thesis, submitted to the School of Medicine at the Federal University of São Carlos, is a reflective narrative on the choice of a medical degree and the path taken toward its completion. The work is divided into three parts: a brief history regarding the choice of study and the pre-undergraduate period; an analysis of the undergraduate years, addressing academic, personal, and athletic experiences; and, finally, a reflection on the choices made and future perspectives.
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    Raw data on metal accumulation and oxidative stress biomarkers in Nile tilapia exposed to to settleable atmospheric particulate matter (SePM)
    (Universidade Federal de São Carlos, 2024-11-10)
    Maraschi, Anieli Cristina
    ;
    Adorno, Henrique Aio
    ;
    Monteiro, Diana Amaral
    ;
    https://lattes.cnpq.br/5896110724916724
    ;
    https://lattes.cnpq.br/7384615643107023
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    Tecnologia e inovação na produção de whey protein e pre-workout no Brasil
    (Universidade Federal de São Carlos, 2024-11-11)
    Kawano, Gabriel Yamamoto
    ;
    Neves, Isabelle Cristina Oliveira
    ;
    https://lattes.cnpq.br/3479449098249392
    The notion that nutrition can play a crucial role in promoting a healthy life is not new. As early as antiquity, Hippocrates correlated food with medicine. In recent years, the growing interest in a healthy lifestyle has driven the demand for dietary supplements. These products have been marketed for various purposes, such as increasing muscle mass and reducing body fat. This study aimed, through a literature review conducted from January to October 2024, by researching descriptors across different databases, to understand the technologies and innovations involved in the production of dietary supplements in Brazil, with a focus on the processing of whey protein and pre-workout products. It was found that the literature addresses more aspects related to whey protein than to pre-workout supplements. Furthermore, the market offers a variety of whey protein-based products, such as protein bars and yogurts, and caffeine-based products, such as super coffee. Additionally, few sources discussed the use of dietary supplements as essential ingredients for the development of new food products. Notably, for pre-workout supplements, no innovations were identified among the studies analyzed. It is concluded that dietary supplements show high potential for the development of new products, offering health benefits and enhanced performance. Moreover, the need for further studies on the new potential uses of these products as food ingredients was identified.
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    Exploración del potencial catalítico de Metal-Organic Frameworks con sitios de coordinación insaturados en síntesis orgánica
    (Universidade Federal de São Carlos, 2024-11-11)
    Báez Gómez, Reynier
    ;
    Jiménez, Claudio Águila
    ;
    https://orcid.org/0000-0002-2622-8308
    ;
    Paixão, Márcio Weber
    ;
    https://lattes.cnpq.br/3773908504964104
    In recent years, Metal-Organic Frameworks (MOFs) have gained relevance in various applications, they stand out in heterogeneous catalysis due to their unique properties, such as high porosity and specific surface area, thermal stability, and the ability to incorporate catalytically active centers. In this work, the synthesis, characterization, and catalytic evaluation of four MOFs were carried out: HKUST-1, MIL-101(Cr), UiO-66-NH2, and MIL-53(Al). The synthesis of MIL-53(Al) through up-cycling from aluminum cans and PET bottles is particularly notable, promoting the circular economy by demonstrating the feasibility of producing MOFs from waste materials. MOFs were evaluated as heterogeneous catalysts in two C-N bond-forming reactions. For the first time, MOFs were reported as catalysts in the synthesis of acylhydrazides from aldehydes and azocompounds. The reaction was carried out at 60 °C for 48 hours in ethyl acetate, obtaining 16 compounds with yields ranging from 54 % to 97 %. The synthesis of pyrroles via the Paal-Knorr reaction from anilines and acetylacetone was also studied. The reaction was conducted under solvent-free conditions using microwave irradiation for 5 minutes, producing 7 pyrroles with yields between 50 % and 96 %. In both reactions, MIL-53(Al) proved to be the most efficient catalyst, with catalyst loads of 10 mol % and 5 mol %, respectively. Additionally, the stability and reusability of MIL-53(Al) were evaluated over four consecutive catalytic cycles, maintaining its performance with minimal decline. The combination of high catalytic activity, stability, and sustainable origin of MIL- 53(Al) represents a significant advancement in heterogeneous catalysis and green chemistry. The pioneering application of MOFs in the synthesis of hydrazides expands the frontiers of catalysis with these materials, providing a clear example of how the principles of the circular economy and catalysis innovation can be applied in the synthesis of advanced materials and the development of more efficient and environmentally friendly chemical processes.
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    Experiência em estágios e intercâmbios durante a graduação em Medicina
    (Universidade Federal de São Carlos, 2024-11-11)
    Ferreira, Brenda Emanuelly de Campos
    ;
    Barbosa, Larissa Campagna Martini
    ;
    https://lattes.cnpq.br/8969823407559809
    ;
    https://orcid.org/0000-0002-4766-0634
    ;
    https://lattes.cnpq.br/4198405762849898
    This undergraduate thesis in medicine at the Federal University of São Carlos (UFSCar) is an experiential report of placements at the Santa Casa de Misericórdia in Anápolis, Goiás, Brazil, and at the Clermont-Ferrand University Hospital Estaing in France. The study highlights the benefits of practical learning for medical students, such as exposure to different hospital and cultural contexts, which contributes to a more humanized medical education. The challenges and achievements of these placements and academic exchanges are discussed, highlighting the importance of practical experience in developing professional and personal skills. The work aims to inspire other students to seek similar experiences and to make the academic journey more accessible by sharing information about the frequency of public calls and the importance of internship and exchange opportunities.
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    Minha trajetória no curso de medicina da UFSCar: reflexões, afetos e sentidos a partir da formação médica
    (Universidade Federal de São Carlos, 2024-11-12)
    Carvalho, Aline Augusto de
    ;
    Mattos, Augustus Tadeu Relo de
    ;
    https://lattes.cnpq.br/2647316578139332
    ;
    https://orcid.org/0000-0002-0514-3575
    ;
    https://lattes.cnpq.br/1215287799987829
    Reflective narrative based on the trajectory of a medical student over 6 years in a course based on active learning methodology. The first years of the degree brought the challenge of adapting to the method in addition to the interruption of activities due to the COVID-19 pandemic in 2020. The course's approach has the potential to develop critical-reflective reasoning, with evidence-based and practical learning from the first year onwards, achieving humanized training, respect for the potential of each individual and the intellectual growth of its graduates.
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