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Processos educativos na prática de agricultura urbana das Mulheres do GAU: diálogos na zona leste de São Paulo
(Universidade Federal de São Carlos, 2025-08-29)
Ferreira, Larissa
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Teixeira, Iraí Maria de Campos
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https://lattes.cnpq.br/8274452304759860
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https://orcid.org/0000-0003-0307-3443
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https://lattes.cnpq.br/5048711015207265
América Latina se caracteriza por diversos intentos de homogeneización de las interpretaciones del mundo, a partir de una lógica dominante que refuerza las estructuras de opresión en la sociedad. En la ciudad de São Paulo, la periferia popular se ha consolidado en una realidad compleja, en la medida en que la planificación urbana no ha respondido a sus demandas en diferentes momentos históricos. Este contexto forma parte de la realidad del colectivo “Mulheres do GAU (Grupo de Agricultura Urbana)”, con el que esta investigación promueve investigaciones y diálogos. En diversos contextos latinoamericanos, la Educación Popular se consolida como praxis educativa, afirmándose en la lucha por la justicia social. En esta perspectiva, la investigación tiene como objetivo comprender y problematizar los procesos educativos revelados por la práctica social de la agricultura urbana realizada por las “Mulheres do GAU”, buscando comprender las contribuciones de estos procesos educativos y cómo las mujeres interpretan el espacio urbano en el que actúan. La investigación es de naturaleza cualitativa y la metodología adoptada es la investigación participante, en la que la convivencia dialógica con el colectivo fue fundamental. La producción de datos se realizó mediante la observación participante, entrevistas semiestructuradas y círculos de conversación. La información fue recopilada e interpretada mediante el análisis de contenido. Los resultados muestran cómo las “Mulheres do GAU”, a través de la agricultura urbana, abordan situaciones límite y deshumanizantes, como la discriminación por motivos de género y raza, la exclusión urbana y los desafíos de ser agricultora en la ciudad. Y así, anuncian diversos procesos educativos, tales como el reconocimiento de sus voces; la ampliación de sus lecturas del mundo; la acogida; la cooperación; los intercambios de conocimientos; la comprensión de cómo lidiar con los conflictos; el sentimiento de pertenencia; el respeto y el amor por la naturaleza, que incluye a los seres humanos y no humanos; el reconocimiento de su trabajo; y cómo sus experiencias de vida constituyen sus formas de ser agricultoras urbanas. También enseñan y aprenden a ser esperanzadas, en el sentido de señalar caminos para hacer las cosas de manera diferente, reivindicando posibilidades de humanización en el trabajo. Con la conclusión de esta investigación, esperamos haber contribuido a la comprensión del universo de la agricultura urbana en la ciudad de São Paulo, practicada por mujeres, en su mayoría negras, profundizando las discusiones sobre las resistencias y las luchas por la calidad de vida en las periferias populares.
A habilidade de escuta ativa empática do Centro de Ciências Exatas e de Tecnologia da Universidade Federal de São Carlos (UFSCar)
(Universidade Federal de São Carlos, 2025-08-29)
Inácio, Regilene Vieira
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Assis, Karina Gomes de
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https://lattes.cnpq.br/4058077286734344
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Delai, Ivete
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https://lattes.cnpq.br/7054145506480670
This study investigated the level of development of empathic active listening skills among public servants at the Center for Exact Sciences and Technology of the Federal University of São Carlos (CCET/UFSCar). Empathic active listening is a form of listening motivated by the desire to understand others through active engagement, mindfulness, and empathic comprehension. Techniques associated with empathic active listening skills contribute to improved interpersonal communication, making it a required skill for all public servants. In this context, this study aimed to measure the development of empathic active listening skills among public servants at the Center for Exact Sciences and Technology of UFSCar. To answer the research question and understand the measurement of empathic active listening, an integrative literature review was conducted to identify scales for measuring this skill. This study used the Empathic Active Listening Scale (AELS), a selfreport scale comprising three dimensions: detection, processing, and response, along with the listening skills subscale and the opportunity for conversation from the Active Listening Attitude Scale (ALAS). Data were analyzed using exploratory factor analysis. Statistical analysis of the data showed that the CCET/UFSCar presents a moderate level of empathic active listening skills and that the associations between faculty and administrative staff, and between Engineering and Exact Sciences, show the same level of development. The results of this study demonstrated the importance of empathic active listening in the development of interpersonal communication among public servants and the importance of providing training for the development of empathic active listening in the public service. This study contributed to the literature by studying empathic active listening skills among public servants at a Center for Exact Sciences and Technology of a federal university, filling an academic gap. From a practical standpoint, this research presents an empirical diagnosis of the level of development of empathetic active listening skills among public servants. As a technological product, this study developed a conclusive technical report demonstrating the level of development of public servants at CCET/UFSCar.
Educação midiática crítica: combate à desinformação sistêmica na era da economia da atenção e do capitalismo de vigilância
(Universidade Federal de São Carlos, 2025-08-29)
Savietto, Daniele
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Gomes, Luiz Roberto
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https://lattes.cnpq.br/4768579559449929
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https://lattes.cnpq.br/4445674595016172
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Zuin, Antonio Alvaro Soares
This thesis proposes and substantiates the concept of critical media education as a structural response to systemic disinformation, understood not as an occasional deviation but as a phenomenon that is functional to surveillance capitalism and the instrumental rationality that shapes digital platforms. It differs from notions such as media literacy, educommunication or competence-based models by defending critical media education as a distinct category, anchored in ethical-political foundations and in a critique of informational power structures. Grounded in the Critical Theory of Society (especially Adorno, Horkheimer, Benjamin and Marcuse), the research mobilises the concepts of semiformation and damaged life to explain the vulnerability of subjects to manipulative narratives in a digital environment that reinforces a technical, adaptive and uncritical form of education. The central objective is to analyse, from a theoretical and documentary perspective, how critical formative practices can enable citizens to resist algorithmic logics, the attention economy and symbolic manipulation that permeate the contemporary informational ecosystem. Methodologically, this is a qualitative, theoretical and analytical study, based on a literature review and documentary analysis of public policies and media education programmes in Brazil, Finland and the United Kingdom, with UNESCO’s formulations as an additional reference. The results indicate that, although documents such as the National Common Curricular Base (BNCC) and the Brazilian Media Education Strategy represent important advances, structural challenges remain, such as regional inequalities, fragile federative coordination and gaps in teacher education. The thesis concludes that only a critical media education capable of denaturalising technologies, problematising algorithms and reading disinformation as an expression of the power asymmetries of surveillance capitalism can rebuild the link between education, emancipation and democracy. This requires robust public policies, continuous investment in the critical training of educators and intersectoral coordination that recognises critical media education as a human right and as an instrument of resistance to systemic disinformation.
Recomendações funcionais para a descrição de materiais raros em ambientes digitais na perspectiva das tecnologias e princípios Linked Data
(Universidade Federal de São Carlos, 2025-08-29)
Cunha, Gabriela Aparecida da
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Castro, Fabiano Ferreira de
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https://lattes.cnpq.br/7124931056289027
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https://orcid.org/0000-0002-8712-2654
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https://lattes.cnpq.br/5013785155347994
The digitization of rare cultural heritage materials requires more than simple visual reproduction. It is essential that digitization occurs simultaneously with a detailed description of the object, including data on its production, provenance, and trajectory, ensuring the preservation of its context and historical relevance. Thus, the question arises: how has the description of rare materials in digital environments with Linked Data characteristics been discussed in the scientific literature of Information Science? The objective is to investigate initiatives for describing rare materials in digital environments from the perspective of Linked Data in the scientific literature of Information Science, in order to: a) analyze and present the state of the art on the description of rare materials in digital environments with Linked Data characteristics; b) present the standards for describing rare materials and identify their characteristics; c) map the standards, instruments, and initiatives for describing rare materials and their characteristics; d) present and analyze cases of description of rare materials in digital environments with Linked Data characteristics; e) identify similarities and differences in the structuring, representation, and description of rare materials in digital environments; and f) propose recommendations for the description of rare materials with Linked Data characteristics. The methodology used comprised a Systematic Literature Review and an empirical study. As a result, with the aim of studying the cases, initiatives, and instruments identified in the corpus in question, five general categories were established: Models for the representation and organization of bibliographic and cultural data, Ecosystem of tools and projects for data, Cataloging Tools and Standards, Semantic Resources, Spectrum of Metadata Schemas. The research analyzed 29 articles and identified 18 practical cases that demonstrated the conversion of traditional metadata (such as MARC) to semantic models (such as BIBFRAME) and its enrichment through connection with external controlled vocabularies. Recommendations were proposed for the description of rare materials, suggesting the adoption of flexible models (BIBFRAME), open vocabularies, and Web standards (such as JSON-LD and IIIF) to ensure interoperability and access to cultural heritage.
Modelagem e simulação das etapas de liquefação, sacarificação e fermentação do processo de produção de etanol de milho: estudos para otimização do processo
(Universidade Federal de São Carlos, 2025-08-29)
Azevedo, Paulo Gabriel Ferreira de
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Cruz, Antonio José Gonçalves da
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https://lattes.cnpq.br/1812806190521028
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https://orcid.org/0000-0001-6830-9512
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https://lattes.cnpq.br/5454599346752237
The use of corn for first-generation ethanol production has been increasing exponentially in Brazil, making the optimization of this process essential to enhance its competitiveness relative to sugarcane. This study models, simulates, and optimizes the liquefaction (L), saccharification (S), and fermentation (F) stages of corn ethanol production, evaluating four process configurations: (i) sequential L, S, and F (LSF), (ii) simultaneous L and S followed by F (SLSF), (iii) separate L with simultaneous S and F (LSSF), and (iv) simultaneous L, S, and F. Mathematical models based on kinetic parameters and literature data were implemented in Python using Google Colaboratory. Uncertainty propagation in the modeling was analyzed using the Monte Carlo Method (10,000 samples) for ethanol concentrations. A plant operating 330 days per year was simulated to estimate the OPEX, with revenues derived from ethanol, corn oil, and DDGS (Dried Distillers Grains with Solubles). The differential evolution method was employed to maximize the annual net profit. Using initial concentrations reported in the literature, the concentrations of the process components were obtained. The highest uncertainty in final ethanol concentration was 7.45%, observed in the SLSF scenario. In terms of optimization, the SSF scenario resulted in the lowest final ethanol concentration (115 g·L⁻¹), the lowest initial starch concentration (239 g·L⁻¹), and the lowest annual net profit (R$ 27 million). Corn accounted for the highest share of the total product cost averaging 73%. DDGS contributed approximately 31% of the total revenue across all scenarios. The sensitivity analysis indicated that variations in the prices of ethanol, corn, and DDGS were the factors that had the greatest impact on the economic indicators of the simulation, with particular emphasis on the SSF scenario, which showed an approximate 600% variation in its annual net balance. Finally, the LSF scenario presented better economic results.
Condicionantes da participação eleitoral em países africanos de língua oficial portuguesa (2001 a 2023)
(Universidade Federal de São Carlos, 2025-08-29)
Eusébio, Cassiano
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Casalecchi, Gabriel Avila
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https://lattes.cnpq.br/9759794253878555
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https://lattes.cnpq.br/9089401461364258
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Casalecchi, Gabriel Avila
This study analyzes the factors that influence voter turnout in general elections in Portuguese-speaking African countries (PALOP). What are the factors that influence voter turnout in general elections in PALOP countries? Through this research question, we found a theoretical and methodological limitation in comparative studies on the African continent and in PALOP countries specifically. To fill this gap, we reviewed the literature, looking at different micro and macro approaches to electoral participation with reference to African studies. Methodologically, the research uses a series of Afrobarometer surveys combined with institutional and contextual data from PALOP countries. In total, we had 22,747 observations corresponding to the four countries analyzed (Angola, Cape Verde, Mozambique, and São Tomé and Príncipe) referring to nineteen legislative and presidential elections from 2001 to 2023. Using logistic regression and qualitative analysis, we found that individuals who feel close to a political party (party identification) are more likely to vote in PALOP countries. In all countries, low-income individuals were less likely to participate in elections, particularly in Mozambique and, to a lesser extent, Angola. The relationship between institutional trust and participation revealed an ambivalent pattern. In Cape Verde and São Tomé and Príncipe, contexts with greater institutional legitimacy, trust in democracy, the president, and the regime served as a mobilizing factor. In Mozambique and Angola, however, distrust of electoral institutions, such as the CNE, was associated with abstention, especially when accompanied by allegations of fraud or bias. In Angola, the participation of dissatisfied and distrustful voters even exceeded that of satisfied voters—signaling that, in hybrid regimes, voting can be used as an instrument of protest rather than endorsement. Other factors such as age, education, and civic engagement proved to be the main determinants of voter turnout, albeit modulated by different institutional, cultural, and historical contexts in the general elections of the PALOP countries.
Síntese e caracterização de complexos de prata(I) com ligantes quelantes doadores N,N, N,O e N,S: avaliação da citotoxicidade e atividade antibacteriana
(Universidade Federal de São Carlos, 2025-08-29)
Santos, Josenilton De Jesus
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Rocha, Fillipe Vieira
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https://lattes.cnpq.br/5841127259122766
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https://lattes.cnpq.br/8905293463487217
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Rocha, Fillipe Vieira
In this work, silver(I) complexes containing heterocyclic ligands from the phenanthroline and (thio)semicarbazone classes were synthesized and characterized to investigate their antitumor and antibacterial properties. The synthesis was carried out homogeneous conditions, yielding products with good yields (60–88%). The complexes were characterized by techniques including infrared spectroscopy (IR), UV-Vis spectroscopy, 1H and 13C NMR, elemental analysis (CHN), and high-resolution mass spectrometry (UHPLC-QTOF-MS). Cytotoxicity assays revealed significant activity of the complexes against tumor cell lines A2780, MDA-MB-231 and A549, with IC50 values ranging from 0.18 to 7.2 μM. Several complexes exhibited selectivity over the non-tumor cell line MRC-5, with selectivity indices (SI) greater than 5, particularly the [Ag(phendione)(scz)]⁺ complex. Additionally, the complexes showed selective inhibitory activity against topoisomerase IIα, without affecting the IIβ isoform, indicating potentially beneficial enzymatic selectivity. Assays performed with the pUC19 plasmid showed no significant DNA cleavage at the tested concentrations. Microbiological tests demonstrated antibacterial activity against Gram-positive strains (S. aureus, S. epidermidis) and Gram-negative strains(E. coli, K. pneumoniae). The [Ag(phendione)(scz)]⁺ complex stood out with minimum inhibitory concentrations (MIC) ranging from 1.95 to 15.6 μg mL-1. The greater susceptibility observed in Gram-positive bacteria may be attributed to the absence of the lipopolysaccharide outer membrane, facilitating access of the complexes to intracellular targets. Regarding anti-Leishmania activity (promastigotes), complexes containing phendiona or batophen exhibited submicromolar EC₅₀ values: 0.2–0.5 μM for L. amazonensis and 0.3 – 0.5 μM for L. braziliensis, with cytotoxicity in RAW 264.7 within 1.6 – 3.8 μM, resulting in selectivity indices (SI) frequently > 8 (up to ~12.7, depending on the system). Taken together, the results identify Ag(I) complexes with N,O/N,S-donor ligands as multifunctional candidates with relevant potency and selectivity, directed interaction with biomolecular targets (topo IIα), and broad activity spectrum (tumors, bacteria, and Leishmania), thereby justifying mechanistic studies and in vivo evaluation.
Ecotoxicidade de microplásticos de polietileno e nanopartículas de dióxido de titânio isolados e conjugados nas brânquias e fígados de girinos de Aquarana catesbeiana (Shaw, 1802)
(Universidade Federal de São Carlos, 2025-08-29)
Fujiwara, Gabriel Hiroshi
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Carvalho, Cleoni dos Santos
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https://lattes.cnpq.br/7233550271936621
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https://lattes.cnpq.br/5331868024785356
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Waldman, Walter Ruggeri
Currently, according to the Second Global Amphibian Assessment, habitat degradation is recognized as one of the main causes of amphibian population decline, with pollution being a major contributing factor to this loss. Among the emerging pollutants that have gained attention—both for their economic relevance and their potential environmental impacts—are microplastics and nanomaterials. Although the individual effects of these pollutants on amphibians have already been studied, significant gaps remain regarding the combined responses triggered by different classes of microplastics and nanoparticles. Given the urgency of understanding this ecotoxicological dynamic, the present study aimed to evaluate the responses of oxidative stress biomarkers, antioxidant enzymatic activity, and detoxification processes in the livers and gills of bullfrog (Aquarana catesbeiana) tadpoles exposed to polyethylene microplastics (PE-MPs) (60 mg/L) and titanium dioxide nanoparticles (TiO₂-NPs) (10 μg/L), both individually and in combination, after 15 days of exposure. Laboratory analyses demonstrated that co-exposure to microplastics and nanoparticles induced greater responses in both organs. In the gills, the mixture of these compounds resulted in increased activity of superoxide dismutase (SOD), while the groups treated individually with PE-MPs or TiO₂-NPs showed no significant changes in enzymatic levels or oxidative stress indicators. In the liver, co-exposure led to increased activity of glutathione S-transferase (GST) and elevated levels of lipid peroxidation. In the group exposed only to PE-MPs, an increase in SOD activity and lipid peroxidation levels were observed. On the other hand, neither organ exposed exclusively to TiO₂-NPs exhibited significant alterations in the analyzed parameters. These results reveal the complexity of interactions between these two contaminants and highlight the importance of studying the toxicological effects of pollutants across different organs, considering that each tissue may respond differently to various substances and that the distribution of these compounds within the organism is not uniform. Furthermore, additional studies are needed to understand the mechanisms underlying these biochemical responses, as well as further investigations into how these substances may impact other amphibian species and the ecosystems they inhabit.
An obstruction to topological embeddings between generalized manifolds
(Universidade Federal de São Carlos, 2025-08-29)
Budtinger, Odete Lara Melo
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Santos, Edivaldo Lopes dos
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https://lattes.cnpq.br/2167472456497730
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https://lattes.cnpq.br/5957304437174421
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Saeki, Osamu
This work presents a study of a certain class of obstructions to the existence of a proper homotopy between a proper continuous map and a proper topological embedding between generalized manifolds, without assuming any smooth structure. Such a class was studied by Carlos Biasi, Janey Daccach, and Osamu Saeki in 1 using generalized manifolds, and in 2 assuming a smooth structure. Using this class, we derive some interesting applications involving Euler classes, Haefliger’s obstruction, self-intersection sets, and real projective spaces.
Influência do cátion manganês-II como agente abiótico no metabolismo secundário de fungos extremófilos do gênero Talaromyces
(Universidade Federal de São Carlos, 2025-08-29)
Alves, Mauricio Augusto Pinto Moreno da Silva
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Rodrigues Filho, Edson
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https://lattes.cnpq.br/3667941735597178
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https://orcid.org/0000-0003-4305-0326
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https://lattes.cnpq.br/0492505516508288
This study investigated the impact of the manganese-(II) cation as an abiotic inducer in modulating the secondary metabolism of extremophilic fungi of the genus Talaromyces, with a focus on the production of bioactive compounds with antioxidant potential. Three experimental models were conducted using the species Talaromyces sp., Talaromyces fuscoviridis, and Talaromyces aureolinus, cultivated in modified media containing different concentrations of Mn²⁺, aiming to activate latent biosynthetic pathways and promote the generation of novel or poorly explored secondary metabolites. In Chapter 1, the effect of increasing manganese concentrations (0 to 1000 mM) on the metabolic profile of Talaromyces sp. was evaluated, with emphasis on significant alterations in polyketides involved in the mixed pathway of meroterpenoid biosynthesis. Seven compounds were isolated and characterized by NMR and HRMS, including phenols and hydroxybenzoic acids. Multivariate analyses (PCA and dendrogram) revealed that intermediate concentrations (125 and 250 mM) induced distinct changes in the chemical profile, suggesting disruption in the biosynthesis of specific metabolites. In Chapter 2, the extracts were subjected to antioxidant screening using an adapted DPPH-UPLC assay. The addition of Mn²⁺ enhanced the antioxidant activity of specific fractions, correlating oxidative stress with the increased production of phenolic and aromatic compounds. GC-MS analysis allowed the annotation of substances absent in the control extracts. In Chapter 3, the study focused on the fungus Talaromyces fuscoviridis, isolated from soil contaminated by copper mine tailings. The production of polyene steroids was stimulated by cultivation in rice supplemented with Mn²⁺, resulting in the isolation of two major compounds: Ergosta-3(4),7,14,22-tetraene (1a), unprecedented in the literature, and Ergosta-5,7,14,22-tetraen-3β-ol (2a), with structures confirmed by 1D/2D NMR, HRMS, and X-ray diffraction. Both exhibited antioxidant activity greater than 80% compared to β-carotene at low concentrations. PCA analysis showed clear separation between samples with and without Mn²⁺, confirming the inducing role of the cation in steroidal biosynthesis. Finally, in Chapter 4, three lactone depsidones were isolated and quantified from Talaromyces aureolinus grown in Czapek medium and rice supplemented with manganese: compound 1 (11-hydroxy-3-(1-hydroxy-3-methylbutyl)-4-methoxy-9-methyl-5H,7H-dibenzo[b,g][1,5]dioxocin-5-one), compound 2 (7-hydroxy-4,11-dimethoxy-3-vinyl-5H,7H-dibenzo[b,g][1,5]dioxocin-5-one), and compound 3 (1,6-dihydroxy-8-methyl-11H-dibenzo[b,e][1,4]dioxepin-11-one). Quantification by UPLC-MS indicated that Mn²⁺ favored the production of all three isolated compounds, suggesting a selective effect on the lactone biosynthetic pathway. The integration of spectroscopic data and molecular networking (GNPS) revealed alterations in the global chemical profile, with distinct clustering between treatments with and without Mn²⁺. The results demonstrate that manganese acts as an effective modulator of metabolic expression in extremophilic fungi, favoring the production of metabolites with biotechnological potential. This research contributes to the understanding of the adaptive response of these organisms to metal-induced stress and provides a basis for the rational exploration of microbial biodiversity as a source of novel bioactive compounds.
Leveduras Não-Saccharomyces para produção de etanol em mostos de cana-de-açúcar
(Universidade Federal de São Carlos, 2025-08-29)
Lima, Judieldo de Morais
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Ceccato-Antonini, Sandra Regina
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https://lattes.cnpq.br/7600793543184032
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https://lattes.cnpq.br/2742226360127789
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Bastos, Reinaldo Gaspar
The main yeast used in the industrial ethanol production process is Saccharomyces cerevisiae. However, non-Saccharomyces yeasts may offer some advantages, such as greater adaptation to the fermentation environment and greater genetic diversity. Alcoholic fermentation is an essential step in fuel ethanol production, where factors such as must composition, process conduction system, and yeast treatment affect process efficiency. Therefore, this study aimed to evaluate the potential of non-Saccharomyces yeasts (Wickerhamomyces anomalus, Meyerozyma guilliermondii, and Scheffersomyces stipitis) for ethanol production from sugarcane musts compared to industrial strains of S. cerevisiae (PE-2 and CAT-1). Initially, the stress tolerance (pH, temperature, glucose, and ethanol concentrations) of the yeasts was evaluated in microplates and spot assays. There was a difference between the yeasts S. cerevisiae CAT-1 and PE-2. Among the non-Saccharomyces, W. anomalus and M. guilliermondii presented tolerance profiles closer to the industrial ones, with W. anomalus being similar to PE-2 and M. guilliermondii to CAT-1. Both non-Saccharomyces strains demonstrated promising characteristics for the ethanol fermentation process under typical industrial stresses. Next, the growth and ethanol yield of the yeasts were evaluated in three different sugarcane-derived musts (molasses, broth, and mixed) at a concentration of 40 g/L total reducing sugar, under agitation, at 30 °C. Molasses promoted an increase in cell number for S. cerevisiae and non-Saccharomyces strains. Strain PE-2 had the highest ethanol yield in 12 h, with little variation between media, while CAT-1 achieved its best yield in broth after 24 h. For S. stipitis and W. anomalus, the best yields occurred in broth, with M. guilliermondii showing the highest growth in molasses, but with similar yields in broth and molasses media. Considering molasses as a medium for cell propagation and fermentation, fermentation tests were performed in a fed-batch system with cell recycling (six cycles) in molasses, also evaluating the effect of treating the cells with sulfuric acid between fermentation cycles. The yeasts S. cerevisiae CAT-1 and M. guilliermondii were selected, and cell viability and fermentation parameters were evaluated. Cell recycling reduced the fermentation rate and viability of both yeasts. For M. guilliermondii, acid treatment decreased viability but maintained yield (50% of theoretical), indicating tolerance to acid stress and a limitation related to its fermentation capacity. For S. cerevisiae CAT-1, acid treatment increased yield, despite reducing viability and budding. M. guilliermondii was not competitive with S. cerevisiae in terms of fermentation yield, although it demonstrated that even with acid treatment and cell recycling, it can maintain cell viability at levels that do not impact its ethanol yield, although much lower than that demonstrated by S. cerevisiae CAT-1.
Estudo da resistência de genótipos de soja à herbivoria de Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae)
(Universidade Federal de São Carlos, 2025-08-29)
Arroyo, Victoria Patricia Pena
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Forim, Moacir Rossi
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https://lattes.cnpq.br/1234565160573730
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Wouters, Felipe Christoff
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https://lattes.cnpq.br/4392349445398645
La soja [Glycine max (L.) Merrill] posee una elevada importancia socioeconómica, siendo Brasil su principal productor y exportador. Sin embargo, este cultivo enfrenta desafíos debido a plagas como Spodoptera frugiperda (SF), que comprometen su productividad. El control químico, aunque ampliamente utilizado, favorece la aparición de plagas resistentes y genera impactos ambientales y sobre la salud. Para mitigar estos efectos, las plantas activan mecanismos de defensa, produciendo compuestos que afectan el desarrollo y el comportamiento de los insectos. El uso de cultivares resistentes es una estrategia clave para minimizar pérdidas, dado que dichas defensas varían según el genotipo, el órgano vegetal y el tipo de herbivoría, lo que hace crucial su identificación y comprensión en la interacción insecto-planta para mejorar la caracterización de la resistencia en soja. En este contexto, el presente estudio investigó la resistencia de cuatro genotipos cultivados de soja (PI 229358, IAC 100, BRS 257, IAC PL-1) y uno silvestre (PI 407270) frente a la herbivoría de SF, considerando los efectos de la domesticación. Se realizaron ensayos biológicos, análisis nutricionales y metabólicos en hojas jóvenes, maduras y dañadas en el estadio de desarrollo V3, antes y después de la inducción por SF. El perfil metabólico fue analizado mediante UHPLC-q-TOF-MS/MS, utilizando un enfoque no dirigido. PI 229358 e IAC 100 demostraron resistencia constitutiva, mientras que BRS 257, IAC PL-1 y PI 407270 presentaron tolerancia. Las hojas jóvenes concentraron compuestos como ácidos grasos insaturados, octadecanoides y diterpenos, mientras que las hojas maduras mostraron mayor abundancia de flavonoles y triterpenos. La herbivoría activó respuestas metabólicas, especialmente en las variedades resistentes y en la soja silvestre. Se anotaron biomarcadores de resistencia a SF, como derivados de quercetina, isoflavonas, triterpenoides, una cumarina, ácidos grasos y fitoprostanos. El estudio evidencia que la domesticación no eliminó completamente la resistencia y destaca la complejidad de los mecanismos de defensa de la soja, contribuyendo al mejoramiento de cultivares y a estrategias sostenibles de control de plagas.
Desenvolvimento de blendas ternárias com poli (álcool vinílico) e policaprolactona como estratégia de redução da sensibilidade à água de filmes de amido termoplástico
(Universidade Federal de São Carlos, 2025-09-01)
Nicolino, Marcos Vinícius Batista
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Costa, Lidiane Cristina
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https://lattes.cnpq.br/8246109223926480
;
https://orcid.org/0000-0002-0280-6994
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https://lattes.cnpq.br/2729083804454349
Polymeric solid waste management remains inefficient in mitigating the environmental consequences of improper disposal, motivating the development of biodegradable materials such as thermoplastic starch (TPS), derived from renewable sources. However, TPS is moisture-sensitive and shows tensile strength and elongation at break values about three times lower than those of low-density polyethylene (LDPE), requiring modifications to achieve comparable performance. In this work, TPS blends, with and without citric acid, were formulated with up to 20 wt% poly(ε-caprolactone) (PCL) and up to 30 wt% poly(vinyl alcohol) (PVOH) to produce flexible films. The strategy was based on the hypothesis that combining a polar polymer, a nonpolar polymer, and a modifying agent would direct the morphological development of the ternary system, enabling control over water interaction kinetics while preserving biodegradability. The study comprised: (i) TPS development from different vegetal sources and citric acid concentrations; (ii) definition of the mixing protocol for TPS/PVOH binary blends; and (iii) thermodynamic prediction of ternary blend morphology by correlating surface tensions with observed structures. A strong interaction between TPS and PVOH phases was observed, whereas PCL formed polydisperse domains and migrated toward the film surface. The resulting morphologies directly influenced film properties, leading to tensile strength and elongation at break values up to 15 times higher than neat TPS and wettability comparable to pure PCL with only 20 wt% PCL. Although PCL reduced soil deterioration, it did not inhibit biodegradation. The resulting TPS/PVOH/PCL blends may enable applications requiring a balance between stability in use and biodegradability, such as controlled-release systems and packaging films.
Tecnoestresse no trabalho: um estudo sobre antecedentes e consequentes na administração pública brasileira
(Universidade Federal de São Carlos, 2025-09-01)
Finotti, Mariana Ribeiro
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Ubeda, Cristina Lourenço
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https://lattes.cnpq.br/6696784421924024
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https://orcid.org/0000-0001-6460-9462
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https://lattes.cnpq.br/3133614045321129
This research aims to analyze the impacts of antecedents and impacts of technostress on consequential factors at work for civil servants in the Brazilian public administration. The term technostress refers to the stress caused by the excessive use of information and communication technologies (ICT), such as computers, smartphones, and other electronic devices. The constant evolution of technology has changed the way organizations operate, bringing both benefits and challenges. Furthermore, the rapidly developing digital transformation in the public sector involves gains in efficiency and agility, as it will lead to improved relationships between public administrations and their stakeholders, resulting in greater citizen satisfaction and, most importantly, a change in bureaucratic and organizational culture. Given the theoretical gap resulting from the lack of studies on technostress in the Brazilian public sector, this study employed a quantitative research approach, using the quantitative survey method with PLS-SEM modeling. The investigation addresses antecedent factors that favor the emergence of technostress and consequential factors involving negative effects arising from technological interaction. A structured questionnaire was used as a data collection instrument, divided into 6 closed questions, on a 5-point Likert scale, sent to public servants from different spheres, electronically. The findings highlight an understanding of organizational factors as triggers of technostress, a predominance of studies on the implications for women, and the negative impacts of technostress on mental health. This study also highlights strategies that promote healthy technology use and ensure a more balanced and productive work environment in public administration. This research contributes to the theoretical discussion of technostress in the workplace, considering both the needs of individuals and organizations to build a balanced relationship. As practical implications for mitigating technostress in public administration, the study suggests guidelines for implementing support and well-being policies, improving the usability of technology in the workplace, and promoting a healthy work-life balance. Furthermore, the survey largely included responses from federal employees, which may limit the generalizability of the results to the entire national public administration, which is characterized by a wide variety of organizational structures. The study's originality also stands out, as it innovatively addresses the individual and organizational factors that can contribute to technostress, as well as their individual and organizational impacts and correlations.
Efeitos da melatonina e do extrato padronizado de Angelica keiskei e Panax ginseng sobre a performance física
(Universidade Federal de São Carlos, 2025-09-01)
Neves, Ana Júlia Flor
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Beck, Wladimir Rafael
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https://lattes.cnpq.br/3124811889307056
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https://orcid.org/0000-0001-7176-2713
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https://lattes.cnpq.br/7477297431882696
Herbal extracts of Panax ginseng (P. ginseng) and Angelica keiskei (A. keiskei) demonstrate ergogenic potential, promoting fatigue reduction with a chronic effect on increasing mitochondrial content. Melatonin also stands out for its ability to improve mitochondrial function and energy metabolism acutely, both of which are beneficial in endurance exercise. This study analyzed the ergogenic effect of a standardized herbal extract of A. keiskei and P. ginseng, as well as melatonin, to determine whether the combination of these substances improves performance compared to their use alone. The experiments were divided into two phases. Experiment I investigated the effects of the herbal extract of A. keiskei and P. ginseng on tissue and serum markers, without the influence of exercise. Experiment II evaluated the ergogenicity of the herbal extract and melatonin, as well as their combination. Sixty 45-day-old Wistar rats were used: 1) two groups of non-exercised animals: control group (CT) and herbal group (FIT); and 2) four groups of exercised animals: exercised control (CTEx), exercised herbal (FEx), exercised melatonin (MEx), and exercised herbal extract + melatonin (FMEx). In experiment I, the administration of the herbal extract (FIT) or vehicle solution (CT) was performed via orogastric gavage for 21 days at 90 days of age, followed by euthanasia at 111 days of age. In experiment II, aquatic familiarization took place at 76 days of age, and the Critical Load Test in swimming exercise (CLT) at 86 days of age. At 90 days of age, the administration of herbal extract (FEx and FMEx) or vehicle solution (CTEx and MEx) began. At 111 days of age, melatonin (MEx and FMEx) or vehicle solution (CTEx and FEx) was administered intraperitoneally 30 minutes before the Time Limit Test (tlim) at 90% of the critical load intensity (iCC). This was followed by euthanasia for the collection of biological materials (blood, skeletal muscle tissue, and liver) for serum, intramuscular, and hepatic glycogen and triglyceride analyses. The level of statistical significance was set at 5%. In experiment I, the administration of the herbal medicine did not alter glucose and triglyceride levels, but increased glycogen in the white gastrocnemius and reduced it in the gluteus maximus and liver. Triglycerides decreased only in the red gastrocnemius. In the TCC, there was no difference between the groups in the parameters: load vs. time and iCC. In experiment II, melatonin, and herbal medicine alone increased swimming time in the tlim. Melatonin increased glucose and decreased glycogen in the white gastrocnemius and soleus muscles. While the herbal medicine decreased serum triglycerides in the liver, white gastrocnemius, and red gastrocnemius muscles, it also reduced glycogen content in the white gastrocnemius, red gastrocnemius, and soleus muscles. Administration of the combination resulted in an increase in tlim (FMEx > CTEx), increased glucose compared to the CTEx/FEx/MEx groups, and reduced glycogen content in the white and red gastrocnemius tissues (FMEx < CTEx). It is concluded that the administration of melatonin and herbal medicine caused ergogenicity with a cumulative effect when combined, with both compounds modulating the consumption of energy substrates differently.
Efeitos da ovariectomia e do treinamento resistido sobre a função e metabolismo energético mitocondrial dos cardiomiócitos do ventrículo esquerdo
(Universidade Federal de São Carlos, 2025-09-01)
Pinto, Regiane
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Shiguemoto, Gilberto Eiji
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https://lattes.cnpq.br/9885031162656978
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https://orcid.org/0000-0001-7621-4329
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https://lattes.cnpq.br/9035737109545307
Menopause is characterized as a physiological process marked by the cessation of menstruation, typically occurring between the fourth and fifth decades of a woman’s life. The main feature of this period is the abrupt decline in 17β-estradiol (E2) levels, a hormone with cardioprotective effects. Ovarian hormones are associated with biochemical and functional changes, including impairment of the electron transport chain (CTE) and reduced ATP production, which contribute to mitochondrial dysfunction and increase the risk of developing cardiovascular diseases (DCVs). Resistance training has emerged as an effective non-pharmacological intervention for attenuating the deleterious effects of menopause, promoting improvements in mitochondrial function, hemodynamic parameters, and cardiovascular plasticity. Objective:This study investigated the impacts of ovariectomy, as an experimental model, on mitochondrial bioenergetics in left ventricular cardiomyocytes of Wistar rats, as well as the efficacy of Resistance Training (RT) as a therapeutic strategy to mitigate the effects caused by the reduction of ovarian hormones. Methodology: Twenty Wistar rats were used, divided into four experimental groups (five animals per group): INT-SED (intact sedentary), INT-RT (intact trained), OVX-SED (ovariectomized sedentary), and OVX-RT (ovariectomized trained). The analyses included: gene expression by RT-qPCR of mitochondrial complexes (C1, C2, C3, C4, and ATP synthase) and citrate synthase (CS); high-resolution mitochondrial respiration (Oroboros®); and maximum loading capacity. Results: Ovariectomy significantly impaired mitochondrial function in the left ventricular cardiomyocytes, as well as markedly reduced oxygen consumption in coupled respiratory states (S3 and S3Suc), in addition to decreasing the expression of CTE complexes. Conversely, resistance training (RT) was able to promote both functional and molecular improvements, with a significant increase in O₂ consumption and recovery of mitochondrial complex expression.
O impacto do uso de telas por crianças na idade pré-escolar: revisão integrativa da literatura e recomendações para proteção do desenvolvimento infantil pela perspectiva da terapia ocupacional
(Universidade Federal de São Carlos, 2025-09-01)
Matias, Isabela Nogueira
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Martinez, Claudia Maria Simões
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https://lattes.cnpq.br/1371315095038350
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https://orcid.org/0000-0002-8997-2767
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https://lattes.cnpq.br/1094889338768891
Digital technologies can negatively affect the motor, cognitive, emotional, and social development of children, which may impact their engagement in meaningful occupations — a key focus of Occupational Therapy. Consequently, researchers from various fields, concerned about the developmental impacts of excessive screen time, have sought to understand how this practice occurs in different daily life contexts. This highlights the need to find a balance between technological exposure and the promotion of activities that foster healthy and holistic child development. Objective: To conduct an integrative literature review on the topic of screen use by preschool-aged children over the last five years and, based on it, to systematize recommendations for the protection of child development. Method: This study adopted an integrative literature review methodology, using the CAPES Journal Portal as the search source. Inclusion criteria comprised articles published in the last five years, in Portuguese and English, addressing preschool-aged children. The selected descriptors, combined with the logical operator "AND," were: "Screen Time"; "Smartphone"; and "Child Development." A total of 88 articles were selected, and after reading them, each was summarized. Finally, they were interpreted through a comparison between the publications to be grouped into thematic categories. Results: The analysis of 88 articles (63.64% in English, 36.36% in Portuguese) revealed that the main themes addressed in the literature regarding the impacts of screen time on child development are psychomotor and physical health (50% of articles), followed by risk factors and factors influencing screen use (32.95%), impact on language and cognition (30.68%), socio-emotional and mental health impacts (19.32%), and finally, recommendations and parental mediation strategies for screen use (17.05%). Based on these findings, an educational booklet was created to propose recommendations to protect child development. Final Considerations: Excessive and inappropriate exposure to electronic devices can lead to significant challenges in various areas of child development. Multiple risk factors and influencing factors that modulate these impacts were identified, ranging from the age of initial exposure and the type of content to parental involvement and the family context.
A expressão de valores desiderativos em construções condicionais insubordinadas com [SE AO MENOS] sob um viés cognitivo construcional
(Universidade Federal de São Carlos, 2025-09-01)
Comarim, Maria Julia Bernardo
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Hirata-Vale, Flávia Bezerra de Menezes
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https://lattes.cnpq.br/2797556968074056
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https://orcid.org/0000-0002-9091-9461
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https://lattes.cnpq.br/7592091027326346
Insubordinate constructions (ICs), although frequent in both spoken and written language, are often marginalized in grammatical descriptions, frequently treated as atypical uses of fully subordinated clauses. According to Evans (2007), insubordination is a diachronic process in which a clause originally used in a subordinate structure begins to occur independently, without a main clause. Within the domain of ICs, insubordinate conditional constructions (ICCs) stand out. Among them are uses such as “if only I had money...” (se ao menos eu tivesse dinheiro…), which, although formally similar to canonical conditional clauses, convey different meanings, often marked by a semantics of desire or wish. Evans’s (2007) definition does not account for the wide range of functions and meanings these constructions may exhibit. Several studies have shown that ICCs differ from their subordinated counterparts by presenting distinct morphosyntactic patterns and semantic values, as observed by D’Hertefelt (2015) in her analysis of Germanic languages. The author proposes a typology with three subtypes of constructions like [IF ONLY], or [SE AO MENOS] in Portuguese: potential, irrealis, and counterfactual, defined based on the degree of (im)possibility of realizing the expressed desire, which is reflected in their linguistic form. The present study aims to investigate the construction [SE AO MENOS] in Brazilian Portuguese (BP), seeking to describe its formal patterns and meanings, particularly in relation to the expression of desires. The analysis is grounded in Cognitive Construction Grammar (Goldberg, 1995; 2006), which posits a systematic association between form and meaning. The corpus analyzed consists of 1,262 occurrences of the construction, collected from the social media platform Twitter (now X) during the second half of 2021. This platform was chosen for its ability to provide spontaneous and contemporary uses of the construction in an informal digital context. Based on the data, a typology of ICCs with [SE AO MENOS] in BP was proposed, identifying four recurring morphosyntactic patterns, the most frequent verbs in each, and their associated semantic traits, such as desire, criticism, and lamentation. The analysis revealed the presence of the irrealis and counterfactual subtypes in BP, but no instances of the potential subtype were found, according to the criteria defined by D’Hertefelt (2015). Additionally, the corpus includes occurrences conveying ironic or sarcastic meanings, which are not addressed in the original typology. These cases are not classified as a new subtype, but rather as usage instances marked by an additional pragmatic layer, triggered by discourse markers specific to Twitter language. A categorization of such markers is proposed. Finally, the study suggests an expansion of the constructional network of ICs in BP, based on the observed data, in dialogue with the proposal by Coradini (2022). This research aims to contribute to the empirical description of ICCs in Brazilian Portuguese and to reinforce the importance of associating form, meaning, and usage in the analysis of this type of construction.
Corpos dissidentes e insistentes: pessoas negras com deficiência no município de Sorocaba e o Sistema único de assistência social
(Universidade Federal de São Carlos, 2025-09-02)
Costa, Walkiria Santos
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Coutinho, Luciana Cristina Salvatti
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https://lattes.cnpq.br/2688318704089723
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https://lattes.cnpq.br/0619105875102247
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Dainez, Debora
This dissertation critically analyzes the performance of the Unified Social Assistance System (SUAS) regarding Black people with disabilities in the city of Sorocaba, São Paulo, considering the intersections of race, disability, and social class. Grounded in intersectional theory, the research aims to move beyond the isolated view of disability and reveals how the capitalist social structure produces and reproduces inequalities affecting these subjects. Starting with the 1988 Federal Constitution and the active participation of the disability rights movement during the constituent process, this study discusses the contradictions in the implementation of the National Social Assistance Policy (PNAS) and the Brazilian Inclusion Law (LBI). The methodology includes bibliographic, documentary, and field research, with semi-structured interviews conducted with SUAS professionals and users, emphasizing active listening and the protagonism of the subjects involved. The analyzed data show gaps in policy implementation, persistent tutelary practices, and the invisibility of racial markers in service provision. The study concludes that SUAS, in its current structure, still lacks effective mechanisms to address the multiple oppressions experienced by Black people with disabilities. There is an urgent need for anti-racist, anti-ableist, and intersectional approaches in social assistance services.
Análise de dados históricos sobre o uso da música na Terapia Ocupacional: resgate das atividades musicais na Hull House
(Universidade Federal de São Carlos, 2025-09-03)
Pires, Maria Letícia Pereira
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Silva, Carla Regina
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https://lattes.cnpq.br/6417501858864106
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https://orcid.org/0000-0002-7079-8340
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https://lattes.cnpq.br/6048571556212121
During the settlement house movement in the United States, Hull House (1889–1930) was the setting for experiments that would lay the groundwork for the not yet named Occupational Therapy, which emerged in this context under the influence of various social movements of the Progressive Era, such as feminism and the Arts and Crafts movement. Music was already an established activity at Hull House since 1893. It served as a major cultural center attended by low-income workers and immigrants, coordinated by reformers—mostly women—such as Jane Addams, Ellen Gates Starr, and Eleanor Clarke Slagle. This research is a historical recovery and grouping of archives from this period, highlighting music at Hull House. The methodology used is the interpretive analysis of texts, along with the iconological interpretation of photographic records from the time. In this research, the presence of music at Hull House is revealed in various formats, such as: singing, dancing, musical theater, through instruments and composition, emphasizing the work of musician Eleanor Smith. Music took place in educational settings, such as in classes for children and youth offered by the Hull House Music School, as well as in performances and events for the entire community. This work discusses how these musical activities can be understood as artistic practices that preceded Occupational Therapy, in its sociocultural and therapeutic dimensions, and it aims to contribute to this scarce discussion in the literature.