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Materiais, interfaces e arquiteturas analíticas em sensores eletroquímicos produzidos por manufatura aditiva
(Universidade Federal de São Carlos, 2026-10-20)
Silva, Vinicius Aparecido Oliani Pedro da
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Janegitz, Bruno Campos
;
http://lattes.cnpq.br/7746094938977989
;
https://orcid.org/0000-0001-9707-9795
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http://lattes.cnpq.br/5255244502930127
Fused deposition modeling (FDM) additive manufacturing enables electrochemical sensors with different materials and architectures, although their performance depends on conductive-phase accessibility and electrode/solution interfacial properties. This thesis investigated surface modification, multi-material fabrication, analytical integration, and conductive filament development. First, commercial graphene/polylactic acid (G-PLA) electrodes were treated with N,N-dimethylformamide (DMF) and applied to epinephrine determination, achieving a linear range of 4–100 µmol L-1, a detection limit (LOD) of 0.2 µmol L-1, and recoveries of 96.9–102% in fortified human serum. Next, multi-feed/multi-nozzle printing it allowed for the integration of insulating PLA filaments and carbon black-conductive PLA filaments into a PLA matrix (CB-PLA) without material purging. Following DMF treatment, charge-transfer resistance decreased from 988 to 39.3 Ω. For fenitrothion determination in fortified honey, the sensor exhibited a linear range of 4–200 µmol L-1, an LOD of 1.3 µmol L-1, and recoveries close to 100%. Subsequently, a hyphenated platform combined static electrochemical, microfluidic electrochemical, and paper-based colorimetric detection, enabling three complementary catechol measurements from a single sample aliquot. All modalities showed a linear range of 50–600 µmol L-1, with LODs of 0.2, 1.4, and 16.1 µmol L-1, respectively. Finally, a polypropylene/CB filament containing incorporated Cu (PP/CB-Cu) during thermomechanical mixing was developed for oxalate sensing. Cu incorporation increased the analytical response approximately 3.5-fold compared with PP/CB, yielding a linear range of 10–1000 µmol L-1, an LOD of 2.48 µmol L-1, and recoveries of 95.4–107% in synthetic urine. Together, these findings demonstrate that controlling the interface, fabrication process, analytical architecture, and feedstock composition expands the functionality of additively manufactured electrochemical sensors.
Efeitos do bisfenol-a na capacidade fotossintética e no crescimento de Egeria densa
(Universidade Federal de São Carlos, 2026-10-22)
Praes, Lavínia Carolini Rios
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Cunha-Santino , Marcela Bianchessi da
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http://lattes.cnpq.br/2356641063223397
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https://orcid.org/0000-0001-6048-0745
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http://lattes.cnpq.br/3903264919955823
Bisphenol A (BPA) is an emerging contaminant widely used in the plastics industry; its persistent presence in inland water bodies poses a potential threat to aquatic biota. This study investigated the effects of three BPA concentrations (5 mg L⁻¹ [T1], 15 mg L⁻¹ [T2], and 25 mg L⁻¹ [T3], alongside a control [TC]) on the net photosynthetic rates and growth kinetic parameters of the submerged aquatic macrophyte Egeria densa under controlled laboratory conditions (27 °C and a 12-h photoperiod). Median net photosynthetic rates were 1.75 (TC), 1.00 (T1), 1.25 (T2), and 1.35 mg O₂ g⁻¹ DW h⁻¹ (T3). Although photosynthetic activity decreased, treatment differences were not statistically significant (p > 0.05). In contrast, growth kinetic parameters were highly sensitive to the pollutant, with significant differences (p < 0.05) between the control and the higher-concentration treatments (T2 and T3). The growth coefficient (µ) decreased progressively with increasing contaminant levels: 0.14 day⁻¹ in the TC (doubling time, td = 5 days), 0.07 day⁻¹ in T1, 0.04 day⁻¹ in T2, and 0.02 day⁻¹ in T3; this demonstrates that the control value was seven times higher than that of the treatment with 25 mg BPA L⁻¹. Each 1 mg L⁻¹ increase in BPA reduced the plant growth coefficient by approximately 9%. The half-life of the compound in the experimental media ranged from 6.6 to 8.5 weeks. The results suggest that the growth coefficient of E. densa is a more adequate biometric indicator of BPA contamination than net photosynthetic rate, highlighting the importance of integrated approaches for assessing the toxicity of micropollutants in macrophytes.
Inserção de dispositivo intrauterino de cobre no pós-parto vaginal imediato guiada por ultrassonografia: experiência de Iniciação Científica
(Universidade Federal de São Carlos, 2026-10-26)
Carvalho, Kemelly Aparecida
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Okido, Marcos Masaru
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http://lattes.cnpq.br/5915321013293271
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https://orcid.org/0000-0002-6861-9761
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Martini, Larissa Campagna
The immediate postpartum period represents an important opportunity to offer contraceptive methods, especially in situations in which subsequent access to health services may be limited. The copper intrauterine device (IUD) is an effective and long-acting contraceptive option, although its insertion immediately after vaginal delivery is associated with higher expulsion rates. In this context, this study presents the undergraduate research experience developed at the Federal University of São Carlos, whose objective was to evaluate whether ultrasound-guided insertion of the copper IUD immediately after vaginal delivery would be associated with lower expulsion rates compared with the conventional technique. A randomized, controlled, double-blind clinical trial was conducted, with ultrasound follow-up between 40 and 60 days after delivery. The final sample consisted of 30 participants, 15 in the intervention group and 15 in the control group. Total, partial, and combined expulsion rates were 6.7%, 13.3%, and 20.0%, respectively, in the ultrasound-guided group, compared with 13.3%, 40.0%, and 53.3% in the control group. Although lower rates were observed in the intervention group, no statistically significant differences were identified. The experience contributed to the development of knowledge related to scientific methodology, data analysis, and critical thinking, in addition to representing an important academic opportunity through the Institutional Scientific Initiation Scholarship Program (PIBIC).
Rastreio de situações de trauma entre os profissionais da Atenção Primária à Saúde, por meio do aplicativo APP Mental
(Universidade Federal de São Carlos, 2026-10-26)
Ferreira, Vitória Caroline dos Santos
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Martini, Larissa Campagna
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http://lattes.cnpq.br/8969823407559809
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https://orcid.org/0000-0002-4766-0634
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http://lattes.cnpq.br/4392869893747920
Health professionals work in unpredictable contexts and are exposed to stressful events with traumatic potential, which causes mental health damage, including post-traumatic stress disorder (PTSD). This study evaluates the feasibility of the APP Mental application for the prevention and screening of PTSD symptoms among health professionals, using the Posttraumatic Stress Disorder Checklist (PCL-5). The research adopts a quantitative, cross-sectional design, with approval from the institutional research ethics committee. The sample comprises individuals over 18 years of age, formally employed by the municipal health department and assigned to Primary Health Care services, who interact with the application for 12 weeks. The application administers a sociodemographic questionnaire and asks about experiences of trauma throughout life, and it sends the PCL-5 to users who report trauma, with a cutoff score of 31 or higher. The analysis uses descriptive statistics in RStudio software. The theoretical framework relies on the DSM-5 diagnostic criteria and on studies that associate occupational exposure to traumatic events with psychological distress among health workers. In the partial results, the sample comprises 28 people, mostly women (96.4%), with a mean age of 42 years. Among the 12 PCL-5 respondents, half (50%) score 31 or higher, which indicates greater symptom severity. The study concludes that the preliminary data reinforce the importance of mental health promotion, prevention, and care actions for health workers and indicate the need to develop educational materials on trauma and coping with stress.
CertFix: solução para rotação automática de certificados mTLS para autenticação de microsserviços
(Universidade Federal de São Carlos, 2026-10-27)
Cardoso, Guilherme Silva
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Lucrédio, Daniel
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http://lattes.cnpq.br/9090396559596221
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https://orcid.org/0000-0002-1360-4036
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http://lattes.cnpq.br/9032041229633794
The adoption of microservices expands the attack surface and makes the protection of inter-service communication critical, for which mTLS (Mutual TLS) is one of the most robust mechanisms, as it provides mutual authentication and confidentiality. Its adoption, however, is hindered by certificate lifecycle management, for which manual processes are not scalable and are susceptible to failures, operational errors, and delays. This work developed and empirically evaluated CertFix, an automated mTLS certificate lifecycle management solution with an internal certification authority and a per-host embedded agent that exposes the rotation strategy as an explicit configuration element. The design separates two axes that are often conflated in practice: the algorithm, which orders certificate issuance and revocation operations, and the trigger, either scheduled or driven by a security event. The evaluation followed a controlled Latin square experiment replicated three times, with assignments made by service, over a real mesh of ten microservices under a load of 15 requests per second. The three campaigns totaled 4.4 hours of execution, 212,204 requests, 252 certificate rotations, and 27 fault injections, including the failure of the certification authority, which affected all configurations at the same instant. The gradual strategy sustained rotation without ever leaving the service without a valid credential: measured at the certification authority, coverage was continuous, with an exactly zero invalidity window in all 14 cells attributable to the strategy itself, out of the 18 in the design. The maintenance-window strategy failed in all 18 of its cells, event triggering in all 16 of its cells, and the manual procedure in 9 cells. The denominators differ because the cell whose gap was opened by the preceding strategy, in the discarded transition, is excluded from the strategy that inherited it. Under fault injection, measured against paired control windows without faults, the gap for the gradual strategy remained zero across the three scenarios, and it was the only strategy that retained rotations rather than completing them when the service was terminated, whereas neither of the two window-based strategies did so. The difference between the two orderings, however, is invisible in the metric that would naturally be used to evaluate them: rotation success rate assigned 100 % to all four strategies, 238 out of 238 rotations verified by serial-number matching, both to the strategy that never left the service uncovered and to those that did so in every measured cell. Thus, the central contribution is the empirical observation that the benefit of automation stems from the ordering between issuance and revocation, rather than from automation itself. It is a decision that established tools leave implicit, that conventional rotation metrics fail to reveal, and that the evaluated manual script, which follows the same order as the maintenance window, did not avoid either.
A espiral do cuidado: reflexões sobre o autocuidado na minha formação médica
(Universidade Federal de São Carlos, 2026-10-27)
Brito, Thaís de
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Adler, Maristela Schiabel
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http://lattes.cnpq.br/3896827914383636
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https://orcid.org/0000-0003-0222-9856
;
branca
This work presents a critical-reflective memoir of the author's trajectory through medical school at the Federal University of São Carlos, from 2021 to 2026, through the lens of self-care. Drawing on the ethical commitment, incorporated into the Declaration of Geneva, that physicians must attend to their own health and well-being, and on the high prevalence of psychological distress among medical students in Brazil, the text revisits experiences from the basic cycle, the clinical cycle and the internship, in dialogue with the literature on mental health in medical education and physician well-being. The narrative follows moments of overload and emotional distress, as well as the bonds and achievements that marked each stage. Using as a metaphor the constructivist spiral that structures the program's curriculum, the reflection shows that self-care, like medical learning, is built in layers, lost and regained throughout training, and sustained by a support network. It concludes that caring for oneself is a precondition for caring for others and an inseparable part of medical identity, and that promoting self-care should also be a responsibility of medical education.
Da iniciação científica à formação médica: narrativa reflexiva sobre a produção científica durante a graduação
(Universidade Federal de São Carlos, 2026-10-28)
Lima, Lucas Bermudes
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Gualdi, Renata de Cassia Golçalves
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http://lattes.cnpq.br/3368055115956614
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Andreucci Polido, Carla Betina
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http://lattes.cnpq.br/8276149979667627
This study presents a reflective narrative about the author’s undergraduate research experience during medical school at the Federal University of São Carlos. The experience was centered on the project “Wrist circumference and body mass index in elementary schoolchildren: determination of wrist circumference cut-off points for identifying obesity”, developed from a database of 286 six- and seven-year-old students from public schools in São Carlos, Brazil. The aim is to reflect on how participation in the different stages of the research process contributed to the student’s scientific, academic, and professional development. The trajectory was reconstructed from autobiographical memory, the final research project, and the final undergraduate research report, in dialogue with scientific literature on undergraduate medical research, reflective practice, and Evidence-Based Medicine. The experience included preparing and submitting the project for a scholarship, reviewing the literature, scientific writing, self-directed study of medical statistics, organizing and checking the database, using statistical software, and interpreting correlations and ROC curves. A particularly formative moment occurred when initially incongruent results led to a detailed review of the database and the identification of inconsistencies, reinforcing the understanding that scientific rigor requires questioning, checking, and repeating steps when necessary. Promising findings, presentation of the work at scientific meetings, and academic recognition increased the author’s confidence in his ability to contribute to knowledge production. By the end of the experience, undergraduate research was recognized as having changed not only the understanding of research methods, but also the way scientific papers were critically read, Evidence-Based Medicine discussions were approached, and research was envisioned as part of a professional future. The main transformation was moving from seeing scientific production as something reserved for other people to recognizing it as a personal possibility as well.
A construção do olhar
(Universidade Federal de São Carlos, 2026-10-29)
Frare, Vitoria Makiyama
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Santos, Valter Fausto dos
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http://lattes.cnpq.br/9536458664875589
;
http://lattes.cnpq.br/6969612555832249
This work presents a critical-reflective narrative of my undergraduate medical education at the Federal University of São Carlos. By revisiting personal, academic, and professional experiences throughout six years of training, I reflect on changes in my understanding of medicine, care, and my own professional identity. The narrative follows different stages of this journey, from choosing medicine and entering university during the pandemic to experiences in patient care, research, and extracurricular activities. The main experiences revisited include personal growth in the face of family circumstances, recognition of the influence of socioeconomic conditions on the health-disease process, the development of bonds with patients, encounters with death and the limits of medical practice, and experiences of leadership and personal development through participation in the student athletic association. These experiences helped me understand that medical education extends beyond the acquisition of technical knowledge and also involves communication, relationships, responsibility, teamwork, recognition of my own vulnerability, and an understanding of patients within their social and family contexts. At the end of undergraduate training, I remain aware that medical knowledge is always unfinished and that becoming a physician is an ongoing process. Rather than achieving an ideal professional image, this journey points to a desire to practice person-centered medicine committed to dignified care, the production of knowledge, and the preservation of the human essence of the profession.
Análise crítico-reflexiva de seis anos em um curso de graduação único, desafiador e compensador
(Universidade Federal de São Carlos, 2026-10-29)
Benedini, Victor Daciole
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Santos, Valter Fausto dos
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http://lattes.cnpq.br/9536458664875589
;
https://lattes.cnpq.br/8739110544559917
This study presents a critical-reflective narrative of the medical training journey of a student from the sixteenth cohort of the Medicine program at the Federal University of São Carlos (UFSCar), spanning the period prior to university admission through the final year of undergraduate education. The narrative is organized chronologically according to the years of the medical program, highlighting the main challenges experienced during this period, particularly anxiety and structural limitations of the curriculum, including the lack of adequate practice settings in certain learning environments. It also explores the strengths of the program, notably the quality of its teaching staff and the diverse learning opportunities offered in each stage of training, especially during the final three years. The reflection suggests that the strengths of the program substantially outweigh its limitations and emphasizes the importance of a strong support network during medical education.
Eficácia e segurança das intervenções terapêuticas para síndrome dolorosa miofascial em adultos: revisão de revisões sistemáticas
(Universidade Federal de São Carlos, 2026-10-29)
Barros, Ian Carlos de
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Santos, Valter Fausto dos
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http://lattes.cnpq.br/9536458664875589
;
http://lattes.cnpq.br/6350739393719759
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https://orcid.org/0000-0002-0978-381X
Variation in diagnostic criteria and treatments for myofascial pain syndrome complicates the comparison of evidence and its application to clinical practice. Objective: To synthesize the efficacy and safety of therapeutic interventions for adults with myofascial pain syndrome or symptomatic active trigger points. Methods: An overview of systematic reviews was conducted, with searches in PubMed/MEDLINE, Embase, the Cochrane Database of Systematic Reviews, and Epistemonikos in September 2026. Methodological quality was assessed using AMSTAR 2. The descriptive synthesis considered population, intervention, comparator, outcome, and follow-up, accounting for overlap among primary studies. Selection, data extraction, and appraisal were assisted by generative models, with author review and approval within a “human-in-the-loop” framework. Published certainty ratings were used; no new GRADE assessment or meta-analysis was performed. Results: A total of 231 reviews were included: 150 contributed 317 clinical findings, 61 provided contextual information, and no usable findings were located in the extracted data for 20. Methodological confidence was critically low in 221 and indeterminate in 10. For neck pain, lidocaine provided greater pain relief than dry needling across pooled assessments at two to four weeks (mean difference −2.13 points on a scale from 0 to 10; 95% CI −3.22 to −1.03), with low-certainty evidence and no clear advantage for disability or other outcomes. One trial of low-level laser therapy showed a benefit for pain at treatment completion, without demonstrated persistence at six months. For temporomandibular myofascial pain, one trial favored dry needling over botulinum toxin for pain during chewing at six weeks, without a clear benefit for pain at rest or mouth opening. Adverse events were incompletely reported. Conclusion: The findings suggest pain relief in specific comparisons but do not establish an overall treatment ranking. Methodological limitations, imprecision, and study overlap restrict confidence in the conclusions. Clinical application requires consideration of diagnosis, comparator, functional goals, and duration of benefit, alongside uncertainty about safety.
Entre ciclos: uma narrativa crítico-reflexiva sobre a formação médica
(Universidade Federal de São Carlos, 2026-10-30)
Ferro, Leonardo Furlan
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Nasser, Michel
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http://lattes.cnpq.br/1629054550833348
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https://orcid.org/0000-0003-3087-9784
;
http://lattes.cnpq.br/2890612052207352
This undergraduate thesis is foreseen in the Pedagogical Project of the Medicine course at the Federal University of São Carlos (UFSCar) and consists of a critical-reflexive narrative built from the experience of a student throughout the six years of graduation, between 2021 and 2026. The text goes through the three cycles that compose the course's curricular structure — the basic cycle, the clinical cycle and the internship — relating them to the author's personal experiences: entering university amid the COVID-19 pandemic, adapting to the problem-based learning method, moving to a new city and living alone for the first time, involvement in academic leagues and in the university's sports association, experiences in primary care and home care, and the growing interest in the surgical field over the course of the internship. Throughout the narrative, particular emphasis is given to reencountering a patient followed early in the course, during a home-visit activity, and seen again years later in the surgical center — an episode that illustrates, in practice, the concept of longitudinality of care. The work also addresses the author's experience as an undergraduate research student in the field of cardiology, in the final year of the course, under the supervision of Profa. Dra. Meliza Goi Roscani, along with the challenges of balancing internship duties, residency-exam preparation and the writing of this thesis. It is concluded that the sum of these experiences — academic, clinical and extracurricular — was decisive in shaping a more confident, more communicative professional, more aware of comprehensive patient care.
Três vezes doutora: reflexões de uma médica veterinária em formação médica na UFSCar
(Universidade Federal de São Carlos, 2026-10-30)
Guedes, Débora Stefany Fernandes
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Monti, José Fernando Casquel
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https://lattes.cnpq.br/1641654071358324
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https://orcid.org/0000-0003-0131-7926
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http://lattes.cnpq.br/1796483233407421
This Final Course Paper was prepared in accordance with the guidelines of the Pedagogical Project of the Medical Program at the Federal University of São Carlos (UFSCar), in the form of a critical-reflexive narrative about my experience throughout medical school. The text is organized around a particular feature of my trajectory: I came to medicine already holding a degree in Veterinary Medicine and, during the program, I combined medical training with a PhD in Biotechnology. From this perspective, I discuss the differences and similarities between the two health degrees, with attention to teaching methodologies, clinical reasoning and the relationship with the other in care. I go through the cycles of medical training in chronological order, from the basic cycle to the internship, taking as my main source the reflective portfolios I produced in each educational unit, from which I retrieve records and reflections written in the heat of each moment. I seek to record not only the competencies acquired, but also the subjectivities and transformations that ran through these years.
Produção de mudas cítricas e perspectivas para citricultura brasileira
(Universidade Federal de São Carlos, 2026-12-01)
Oliveira, Mateus Borges de
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Conceição, Patrícia Marluci da
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https://lattes.cnpq.br/6623193710607120
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https://orcid.org/0000-0002-9966-3191
The citrus industry is one of the main activities of Brazilian agribusiness, playing an essential role in generating income, employment, and foreign exchange for the country. This study aimed to analyze the technical and legal aspects involved in the production of citrus nursery plants, as well as to discuss the perspectives and challenges of the Brazilian citrus sector, in order to inform production practices that ensure phytosanitary quality and sector sustainability. Through an integrative literature review, information was gathered from scientific publications, legislation, and technical reports issued by institutions such as MAPA, Embrapa, and Fundecitrus. It was observed that the mandatory use of screened nurseries for citrus seedling production initially established in the state of São Paulo and later extended Nationwide represented a milestone in the modernization of the sector, reducing the spread of diseases such as Citrus Variegated Chlorosis (CVC) and huanglongbing (HLB). The importance of using certified mother plants, implementing sanitary indexing, and applying improved grafting techniques and protected-environment management was also verified. The adoption of rootstocks such as citrandarins and Swingle citrumelo has contributed to greater disease resistance and better adaptation to different edaphoclimatic conditions. Furthermore, the expansion of citrus cultivation into new regions such as Goiás, Mato Grosso do Sul, Bahia, and Paraná reflects not only the search for areas with lower HLB incidence but also economic and structural factors that influence the productive reorganization of the sector. It is concluded that the integration of technology, legislation, and sustainable management is fundamental to ensuring seedling health, competitiveness, and the long-term sustainability of the Brazilian citrus industry.
Análise genética de vacas em relação à sua idade no último parto através de modelos de sobrevivência
(Universidade Federal de São Carlos, 2026-12-03)
Afonso, Eduarda Godoy
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Caetano, Sabrina Luzia
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https://lattes.cnpq.br/2340330162391128
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Zuanetti, Daiane Aparecida
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https://lattes.cnpq.br/8352484284929824
In Brazil, the study of bovine longevity is extremely important due to the country’s position in the export and production of this sector and, for this reason, there is a strong interest in achieving maximum profitability in this activity. The economic longevity of cows is totally related to reproductive performance, with the trait known as the age of the cow at last calving (ACLC) being a very important variable in this context. Since this variable cannot always be perfectly measured in some scenarios, a censoring criterion is generally applied to this characteristic, which is based on the difference between the date of the cow’s last observed calving and the date of the last calving on the farm. If this difference is greater than or equal to 36 months, the cow failed, as she has gone too long without calving and will be discarded. Otherwise, the cow is still considered reproductive and her age at last calving is censored, since there is still a possibility of her having another pregnancy. Therefore, one of the objectives of this study is to genetically analyze the IVUP variable using frailty models applied to survival analysis. The use of this type of model is justified by the inclusion of random effects, allowing the prediction of genetic factors associated with each animal and also considering associations between them. Another objective of the study is to identify genetic variables that influence bovine longevity, and this will be done through a Genome-Wide Association Study (GWAS). The analysis is done using a sample of 862 cows, daughters of 47 different bulls. For confidentiality reasons, the origin of the data is kept secret.