Browsing TCC by Title
Now showing items 4-23 of 75
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Análise filogeográfica do segmento genômico da proteína neuraminidase do H1N1 no Brasil
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 18/04/2022)Seasonal flu, caused by Influenza viruses, is one of the most prevalent viral infections in the world, causing 290-650 thousand deaths annually. Such viruses, whose genome is composed of negatively oriented single-stranded ... -
Análise in silico de um novo composto possível inibidor de ciclooxigenase 2 utilizando docking molecular
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 04/01/2021)This work describes the study of the formation of complexes between the enzyme cyclooxygenase (COX-2) and some of its inhibitors. For this purpose, the known inhibitors celecoxib (CEL), rofecoxib (RCX) and Korean 21 and ... -
Aplicabilidade clínica da técnica CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats) no tratamento da anemia falciforme: uma revisão integrativa
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 18/12/2020)Introduction and objective: Sickle cell disease is the most common hemoglobinopathy in humans and has a high morbidity and mortality rates. It is caused by a point mutation, an A-T substitution (GAG→GTG) in the first exon ... -
Aplicações biotecnológicas da taumatina
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 03/04/2023)Thaumatin is a protein present in the leaves of the plant Thaumatococcus daniellii, native to West Africa. This protein is known for its intensely sweet taste and for being about 2000 times sweeter than sugar. For this ... -
Aprendizado de Máquina para classificação das linhagens de Copia e Gypsy de angiospermas
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 17/12/2021)This study used machine learning algorithms (neural network, decision tree and close neighbors algorithm) to create classification models of 11 lineages of the Copia and Gypsy superfamilies, using angiosperm DNA sequences ... -
Aumento da produção de fenazina-1-ácido carboxílico em E. coli: efeito da superexpressão dos genes tktA e ppsA
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 11/11/2021)Secondary metabolites known as phenazines are nitrogenated aromatic compounds produced particularly by the bacterium genera Pseudomonas and Streptomyces, with applications in fields like biological pest control and biosensors ... -
A autofagia é necessária para a segregação de DNA mitocondrial no Fígado
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 24/06/2021)Mutations in the mitochondrial genome (mtDNA) are ubiquitous in humans and can lead to a broad spectrum of disorders. However, due to the presence of multiple mtDNA molecules in the cell, coexistence of mutant and wild-type ... -
Avaliação de vetores de expressão para Xantomonas ssp. aplicados à produção de goma xantana
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 24/02/2022)Xanthomonas sp. are proteobacteria widely known for its pathogenic association with varied species of plants, such as Xanthomonas campestris, which causes black rot that affects crucifers. Its pathogenicity is partially ... -
Avaliação do co-cultivo de bactérias e microalga Chlorella sorokiniana no tratamento de efluentes
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 03/09/2021)Pollution is a social and health problem, the lack of sewer treatment together with its incorrect disposal are one of the leading sources of aquatic pollution. Microalgae are microorganisms which have the potential for ... -
Avaliação do desenvolvimento do inseto Diaphorina Citri através da alimentação em dieta artificial contendo Cistatinas de citros
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 21/03/2023)Brazil is an essentially agricultural country, being highlighted in citriculture worldwide, especially in the production and export of citrus in natura and concentrated juice. Despite its economic relevance, the crops ... -
Avaliação do domínio ATPásico da proteína não estrutural 3 (NS3) do vírus da Zika e investigação de derivados de hidantoínas e oxadiazol como agentes antivirais baseados na estrutura da proteína
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 20/09/2022)One of the great challenges in the field of public health in Brazil has been related to the existence of flaviviruses that cause diseases with high rates of contamination, such as to Dengue, Zika and Chikungunya. The ... -
Avaliação do potencial antimicrobiano de nanoemulsões à base de compostos de óleos essenciais no controle de espécies de Xanthomonas causadoras do cancro cítrico
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 27/11/2020)Citrus canker is one of the most relevant diseases that affect citrus crops, being responsible for serious economic losses to citrus fruit producers and traders. This disease is caused by Gram-negative bacteria of the genus ... -
Avaliação do potencial biotecnológico de Streptomyces sp. para biocontrole de fungos fitopatogênicos de espécies agrícolas de importância econômica: biocontrole de fitopatógenos por Streptomyces sp.
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 07/02/2024)Fungi are the phytopathogens that most substantially affect global agricultural productivity. The development of sustainable strategies and approaches for the control of phytopathogenic fungi and their respective diseases ... -
Bases bioquímicas e funcionais dos mecanismos de resistência do ensitrelvir e nirmatrelvir contra polimorfismos naturais protease principal de SARS-CoV-2.
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 05/02/2024)The pandemic caused by SARS-CoV-2 has brought various challenges to society, affecting the world socially and economically. After the first cases of COVID-19 were recorded in China, the virus spread rapidly, leading millions ... -
Bioprospecção da atividade antimicrobiana do caldo de fermentação produzido pelo endofítico Paenibacillus terrae isolado de Tabebuia spp. do Cerrado em co-cultivo com Bacillus thuringiensis e Bacillus megaterium
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 18/08/2023)As the second largest Brazilian biome, the Cerrado is classified as a “hot spot” for its several endemic species and the great threat of territorial loss, but its biodiversity is still little known. In this biodiversity ... -
Biossensor eletroquímico para detecção de vesículas extracelulares pequenas provenientes de câncer de mama
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 04/02/2022)Cancer is a group of diseases characterized by the disordered proliferation of cells, which can invade other organs and tissues. Breast cancer (BC) is the most common disease in women worldwide, with more than 2 million ... -
Caracterização da cianobactéria Rhabdoderma lineare: uma abordagem fisiológica, bioquímica e metabólica
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 12/09/2022)Cyanobacteria are a group of single-celled, prokaryote and photosynthetic organisms. It has an enormous morphological, physiological and metabolic diversity and this allows the application of these organisms in several ... -
Caracterização da diversidade filogenética e o legado de paisagens em comunidades de peixes de riacho
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 24/03/2023)Freshwater fish constitute the most diverse group of continental vertebrates recorded, in which the aquatic ecosystems they inhabit are in constant and complex connection with the vegetative area around them. Furthermore, ... -
Caracterização das alterações transcricionais e morfológica da mitocôndria da prole de fêmeas obesas com deficiência da mitofusina 2 no oócito
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 26/01/2024)Heart disease is one of the main causes of death worldwide and research has shown an intrinsic relationship between cardiac effects in offspring and maternal obesity. In addition, there is increasing evidence of the possible ... -
Caracterização de células estromais mesenquimais multipotentes cultivadas na presença de uma molécula moduladora da expressão de ciclo-oxigenase-2
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 28/03/2019)Mesenchymal stromal cells (MSC) are stem cells used in therapeutic applications due to their regenerative and immunomodulatory potential. These cells exhibit paracrine activity, which releases soluble factors that allow ...